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Compact for Safe Cosmetics
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Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards |
Ingredients from packaging: Water; Ethoxydiglycol; C11-15 Pareth-3; Vegetable Fatty Acid; Ethanolamine; Oleyl Alcohol; Fragrance; Sodium Sulfite; Erythorbic Acid; Trisodium EDTA; Polyquaternium-22; Panthenol; Tocopheryl Acetate; Aloe Vera Extract; Chamomile Extract; P-Phenylenediamine; P-Aminophenol; M-Aminophenol; N,N-Bis(2-Hydroxyethyl)-P-Phenylenediamine Sulfate; Resorcinol; 1-Naphthol; 4-Chlororesorcinol; M-Phenylenediamine. Color Developer: Water; Hydrogen Peroxide
Warnings from packaging: THIS PRODUCT CONTAINS INGREDIENTS WHICH MAY CAUSE SKIN IRRITATION ON CERTAIN INDIVIDUALS AND A PRELIMINARY TEST ACCORDING TO ACCOMPANYING DIRECTIONS SHOULD FIRST BE MADE. THIS PRODUCT MUST NOT BE USED FOR DYEING THE EYELASHES OR EYEBROWS - TO DO SO MAY CAUSE BLINDNESS. DO NOT USE IF YOU HAVE SKIN DEPIGMENTATION PROBLEMS SUCH AS WHITE PATCHES ON YOUR SKIN (A CONDITION CALLED VITILIGO), OR IF YOU HAVE A FAMILY HISTORY OF SKIN DEPIGMENTATION PROBLEMS, AS AN ALLERGIC REACTION OR SKIN IRRITATION MAY CAUSE LOSS OF SKIN PIGMENT.
| score | data gap | concerns | |
| P-PHENYLENEDIAMINE | 10 | 52% | Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| RESORCINOL | 10 | 52% | Cancer, Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| P-AMINOPHENOL | 8 | 57% | Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards |
| FRAGRANCE | 8 | 100% | Neurotoxicity, Allergies/immunotoxicity, Miscellaneous |
| M-PHENYLENEDIAMINE | 7 | 63% | Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (NITROSAMINES), Occupational hazards |
| 1-NAPHTHOL | 8 | 60% | Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| ETHANOLAMINE | 5 | 66% | Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| 4-CHLORORESORCINOL | 5 | 68% | Cancer, Violations, restrictions & warnings, Neurotoxicity, Allergies/immunotoxicity |
| HYDROGEN PEROXIDE | 3 | 65% | Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| M-AMINOPHENOL | 6 | 65% | Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Occupational hazards |
| TOCOPHERYL ACETATE | 4 | 81% | Allergies/immunotoxicity, Contamination concerns (HYDROQUINONE) |
| VEGETABLE FATTY ACID | 4 | 72% | Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards |
| SODIUM SULFITE | 3 | 87% | Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive) |
| N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE | 3 | 69% | Cancer, Allergies/immunotoxicity |
| PANTHENOL | 2 | 88% | Multiple, additive exposure sources |
| ETHOXYDIGLYCOL | 2 | 82% | Organ system toxicity (non-reproductive) |
| C11-15 PARETH-3 | 1 | 88% | none identified |
| ERYTHORBIC ACID | 1 | 87% | none identified |
| OLEYL ALCOHOL | 1 | 87% | Irritation (skin, eyes, or lungs) |
| TRISODIUM EDTA | 1 | 86% | Enhanced skin absorption |
| ANTHEMIS NOBILIS (CHAMOMILE) EXTRACT | 1 | 80% | Enhanced skin absorption |
| ALOE BARBADENSIS (ALOE VERA) LEAF EXTRACT ALOE VERA EXTRACT | 1 | 75% | none identified |
| POLYQUATERNIUM-22 | 0 | 100% | none identified |
| WATER | 0 | 0% | innocuous |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more in vitro tests on mammalian cells show positive mutation results | TOCOPHERYL ACETATE | |
| One or more in vitro tests non-mammalian cells show positive mutation results | ETHOXYDIGLYCOL | |
| One or more in vitro tests on mammalian cells show positive mutation results | SODIUM SULFITE, ETHANOLAMINE, ERYTHORBIC ACID | |
| Cancer - limited evidence | N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE, M-AMINOPHENOL, 4-CHLORORESORCINOL, 1-NAPHTHOL | |
| Mutagen - limited evidence | P-AMINOPHENOL, M-PHENYLENEDIAMINE | |
| Cancer - not classifiable/not likely to be human carcinogen | RESORCINOL, P-PHENYLENEDIAMINE, HYDROGEN PEROXIDE |
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Human nervous system toxicant - moderate evidence | P-PHENYLENEDIAMINE | |
| One or more animal studies show reproductive effects at moderate doses | 1-NAPHTHOL, P-AMINOPHENOL | |
| One or more animal studies show reproductive effects at high doses | 4-CHLORORESORCINOL, ETHANOLAMINE, ETHOXYDIGLYCOL, M-AMINOPHENOL, M-PHENYLENEDIAMINE |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in cosmetics (concentration limit) | RESORCINOL, P-PHENYLENEDIAMINE, VEGETABLE FATTY ACID | |
| Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel | 1-NAPHTHOL, 4-CHLORORESORCINOL, M-AMINOPHENOL, M-PHENYLENEDIAMINE, P-AMINOPHENOL, P-PHENYLENEDIAMINE | |
| Determined safe for use in cosmetics, subject to concentration or use limitations - any | 1-NAPHTHOL, 4-CHLORORESORCINOL, M-AMINOPHENOL, M-PHENYLENEDIAMINE, N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE, P-AMINOPHENOL, P-PHENYLENEDIAMINE, RESORCINOL, ALOE BARBADENSIS (ALOE VERA) LEAF EXTRACT, ETHANOLAMINE, M-PHENYLENEDIAMINE |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Strong evidence of human neurotoxicity | P-PHENYLENEDIAMINE | |
| Moderate evidence of human neurotoxicity | FRAGRANCE | |
| One or more animal studies show brain and nervous system effects at very low doses | HYDROGEN PEROXIDE | |
| One or more animal studies show brain and nervous system effects at high doses | ETHOXYDIGLYCOL, 1-NAPHTHOL | |
| One or more animal studies show brain and nervous system effects at moderate doses | ANTHEMIS NOBILIS (CHAMOMILE) EXTRACT, RESORCINOL, P-AMINOPHENOL, M-PHENYLENEDIAMINE, M-AMINOPHENOL, ETHANOLAMINE | |
| One or more animal studies show brain and nervous system effects at low doses | SODIUM SULFITE, 4-CHLORORESORCINOL |
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show endocrine system disruption at high doses | HYDROGEN PEROXIDE, N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE, P-PHENYLENEDIAMINE, ANTHEMIS NOBILIS (CHAMOMILE) EXTRACT | |
| One or more animal studies show endocrine disruption at moderate doses | 1-NAPHTHOL | |
| Human any disruptor - strong evidence | RESORCINOL |
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Human immune system toxicant - moderate evidence | VEGETABLE FATTY ACID | |
| Human skin toxicant - strong evidence | ETHANOLAMINE, M-AMINOPHENOL, M-PHENYLENEDIAMINE, N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE, TOCOPHERYL ACETATE | |
| Human immune system toxicant - moderate evidence | SODIUM SULFITE | |
| Human skin toxicant - strong evidence | 1-NAPHTHOL, 4-CHLORORESORCINOL | |
| Known human immune system toxicant | FRAGRANCE, P-AMINOPHENOL, P-PHENYLENEDIAMINE, RESORCINOL |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient) | ANTHEMIS NOBILIS (CHAMOMILE) EXTRACT, C11-15 PARETH-3, PANTHENOL, ERYTHORBIC ACID | |
| One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient) | TOCOPHERYL ACETATE, TRISODIUM EDTA, N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE | |
| Limited evidence of cardiovascular or blood toxicity | ETHOXYDIGLYCOL | |
| One or more animal studies show broad systemic effects at low doses | RESORCINOL, M-PHENYLENEDIAMINE | |
| Possible human immune system toxicant | VEGETABLE FATTY ACID | |
| One or more animal studies show gastrointestinal effects at very low doses | HYDROGEN PEROXIDE | |
| Possible human immune system toxicant | P-AMINOPHENOL, SODIUM SULFITE, ETHANOLAMINE | |
| Known human respiratory toxicant | P-PHENYLENEDIAMINE | |
| Known human lung and skin toxicant | products that may be aerosolized (airborne); products for use on skin | 1-NAPHTHOL |
*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Occupational hazards related to handling | HYDROGEN PEROXIDE, ETHANOLAMINE | |
| Ingredient not fully labeled - identity unknown | FRAGRANCE |
*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Designated as safe for general or specific, limited use in food | TOCOPHERYL ACETATE, ETHOXYDIGLYCOL, HYDROGEN PEROXIDE, RESORCINOL, SODIUM SULFITE | |
| Used in food or as an additive with limited or no toxicity information available | PANTHENOL | |
| Designated as safe for general or specific, limited use in food | ERYTHORBIC ACID, ETHANOLAMINE |
*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Wildlife and environmental toxicity | RESORCINOL, P-AMINOPHENOL, P-PHENYLENEDIAMINE, M-PHENYLENEDIAMINE, M-AMINOPHENOL |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show skin irritation at moderate doses | ETHOXYDIGLYCOL | |
| One or more animal studies show skin irritation at high doses | SODIUM SULFITE | |
| One or more animal studies show skin irritation at moderate doses | C11-15 PARETH-3, ANTHEMIS NOBILIS (CHAMOMILE) EXTRACT, P-AMINOPHENOL, M-AMINOPHENOL, 4-CHLORORESORCINOL | |
| Human skin irritant - moderate evidence | HYDROGEN PEROXIDE, ETHANOLAMINE | |
| Classified as irritant | P-PHENYLENEDIAMINE | |
| Human any irritant - strong evidence | products for use around the eyes, on the skin, or may be aerosolized (airborne) | OLEYL ALCOHOL |
| Classified as irritant | RESORCINOL, M-PHENYLENEDIAMINE, 1-NAPHTHOL |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to low doses | HYDROGEN PEROXIDE, M-AMINOPHENOL, P-AMINOPHENOL, RESORCINOL | |
| Allowed workplace exposures restricted to moderate doses | VEGETABLE FATTY ACID | |
| Allowed workplace exposures restricted to very low doses | M-PHENYLENEDIAMINE, P-PHENYLENEDIAMINE | |
| Allowed workplace exposures restricted to low doses | 1-NAPHTHOL, ETHANOLAMINE |
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | HYDROGEN PEROXIDE | |
| One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood | P-AMINOPHENOL |
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