

Compact for Safe Cosmetics
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Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: Neurotoxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Contamination concerns, Occupational hazards, Biochemical or cellular level changes |
Ingredients from packaging: Ethyl Acetate; Propyl Acetate; Nitrocellulose; Toluene; Tosylamide/Formaldehyde Resin; Isopropyl Alcohol; MEK; Formaldehyde; Panthenol; Camphor; Polyvinyl Butyral; Hydrolyzed Soy Protein; Acetyl Tributyl Citrate; n-Butyl Alcohol; Sucrose Benzoate; Etocrylene; Heptane; Green 6 (Cl 61565)
Warnings from packaging: EXTREMELY FLAMMABLE! Keep away from heat or flame. Use only as directed. If redness or other signs of adverse reaction occur, discontinue use immediately. Avoid inhalation. Keep out of reach of children.
| score | data gap | concerns | |
| TOLUENE | 10 | 54% | Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Neurotoxicity, Allergies/immunotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (BENZENE), Occupational hazards |
| FORMALDEHYDE | 10 | 47% | Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards, Biochemical or cellular level changes |
| METHYL ETHYL KETONE MEK | 6 | 65% | Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| ETHYL ACETATE | 4 | 78% | Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| BUTYL ALCOHOL | 5 | 61% | Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| D&C GREEN 6 GREEN 6 (CL 61565) | 1 | 73% | none identified |
| ISOPROPYL ALCOHOL | 4 | 72% | Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| TOSYLAMIDE/ FORMALDEHYDE RESIN | 4 | 72% | Allergies/immunotoxicity |
| CAMPHOR | 4 | 69% | Violations, restrictions & warnings, Neurotoxicity, Organ system toxicity (non-reproductive), Occupational hazards |
| ACETYL TRIBUTYL CITRATE | 2 | 88% | Multiple, additive exposure sources |
| PANTHENOL | 2 | 88% | Multiple, additive exposure sources |
| PROPYL ACETATE | 1 | 79% | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| HEPTANE | 2 | 75% | Irritation (skin, eyes, or lungs), Occupational hazards |
| NITROCELLULOSE | 1 | 94% | Organ system toxicity (non-reproductive) |
| ETOCRYLENE | 1 | 89% | Organ system toxicity (non-reproductive) |
| POLYVINYL BUTYRAL | 0 | 89% | none identified |
| HYDROLYZED GLYCINE SOJA (SOY) PROTEIN HYDROLYZED SOY PROTEIN | 0 | 94% | none identified |
| SUCROSE BENZOATE | 0 | 94% | none identified |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more in vitro tests on mammalian cells show positive mutation results | ETHYL ACETATE, CAMPHOR | |
| Cancer - not classifiable/not likely to be human carcinogen | HEPTANE, BUTYL ALCOHOL | |
| Not likely to be carcinogenic in humans | METHYL ETHYL KETONE | |
| Cancer - not classifiable/not likely to be human carcinogen | TOLUENE, ISOPROPYL ALCOHOL | |
| Known human carcinogen | FORMALDEHYDE |
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show reproductive effects at high doses | BUTYL ALCOHOL | |
| Limited evidence of developmental toxicity | ISOPROPYL ALCOHOL | |
| Human nervous system toxicant - moderate evidence | METHYL ETHYL KETONE, ETHYL ACETATE, FORMALDEHYDE | |
| Possible human developmental toxicant | TOLUENE |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Recommendation to minimize use in cosmetics - Keep concentration to minimum: warning from industry safety panel | FORMALDEHYDE | |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | FORMALDEHYDE, TOLUENE | |
| Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel | BUTYL ALCOHOL | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | FORMALDEHYDE, CAMPHOR | |
| Violation of industry recommendations - Unsafe for use in cosmetics | TOLUENE |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study | PROPYL ACETATE | |
| One or more animal studies show brain and nervous system effects at high doses | FORMALDEHYDE, BUTYL ALCOHOL | |
| One or more animal studies show brain and nervous system effects at low doses | CAMPHOR | |
| Strong evidence of human neurotoxicity | TOLUENE, METHYL ETHYL KETONE, ETHYL ACETATE, ISOPROPYL ALCOHOL |
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show endocrine system disruption at high doses | HEPTANE |
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Limited evidence of immune system toxicity | TOLUENE | |
| Known human immune system toxicant | TOSYLAMIDE/ FORMALDEHYDE RESIN, FORMALDEHYDE |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient) | HEPTANE, PANTHENOL, ACETYL TRIBUTYL CITRATE | |
| One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient) | D&C GREEN 6 | |
| Limited evidence of sense organ toxicity | ISOPROPYL ALCOHOL, ETHYL ACETATE | |
| One or more animal studies show gastrointestinal effects at low doses | CAMPHOR, ETOCRYLENE | |
| Known human respiratory toxicant | TOLUENE, METHYL ETHYL KETONE, FORMALDEHYDE | |
| Known human lung and skin toxicant | products that may be aerosolized (airborne); products for use on skin | BUTYL ALCOHOL |
*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Designated as safe for general or specific, limited use in food | PROPYL ACETATE, METHYL ETHYL KETONE, ISOPROPYL ALCOHOL, FORMALDEHYDE, ETHYL ACETATE, CAMPHOR, BUTYL ALCOHOL | |
| Used in food or as an additive with limited or no toxicity information available | PANTHENOL, ACETYL TRIBUTYL CITRATE |
*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Wildlife and environmental toxicity | HEPTANE, TOLUENE |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Human skin irritant - moderate evidence | FORMALDEHYDE | |
| Classified as skin irritant | products for use on skin | TOLUENE |
| Classified as lung and skin irritant | products that may be aerosolized (airborne); products for use on skin | BUTYL ALCOHOL |
| Classified as irritant | HEPTANE, PROPYL ACETATE, METHYL ETHYL KETONE, ISOPROPYL ALCOHOL, ETHYL ACETATE |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Insufficient data to determine safety | HEPTANE, TOLUENE, BUTYL ALCOHOL | |
| Considered safe based on assumption of low absorption | TOLUENE | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | TOLUENE, PANTHENOL, ETHYL ACETATE, BUTYL ALCOHOL, ACETYL TRIBUTYL CITRATE | |
| Not assessed for safety in cosmetics by industry panel | POLYVINYL BUTYRAL, HEPTANE, SUCROSE BENZOATE, PROPYL ACETATE, NITROCELLULOSE, METHYL ETHYL KETONE, ISOPROPYL ALCOHOL, HYDROLYZED GLYCINE SOJA (SOY) PROTEIN, ETOCRYLENE, CAMPHOR |
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to low doses | FORMALDEHYDE, BUTYL ALCOHOL, HEPTANE | |
| Allowed workplace exposures restricted to moderate doses | CAMPHOR | |
| Allowed workplace exposures restricted to high doses | ETHYL ACETATE, ISOPROPYL ALCOHOL, METHYL ETHYL KETONE, PROPYL ACETATE, TOLUENE |
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | FORMALDEHYDE |
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