Top 2 Bottom Basecoat & Topcoat || Skin Deep: Cosmetic Safety Reviews

TOP 2 BOTTOM BASECOAT & TOPCOAT

last updated: 03/15/09 brand: by

SCORE

moderate hazard (out of 10)

75%

data gap

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44% of nail polishs have lower concerns

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company's animal testing policy is unknown.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards

Ingredients from packaging: Butyl Acetate; Ethyl Acetate; Nitrocellulose; Tosylamide/Formaldehyde Resin; Dibutyl Phthalate; Isopropyl Alcohol; Camphor; Benzophenone-1; D&C Yellow No. 11 (CI 47000); FD&C Blue No. 1 (CI 42090)

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ingredients

	score	data gap	concerns
DIBUTYL PHTHALATE	10	49%	Developmental/reproductive toxicity, Violations, restrictions & warnings, Neurotoxicity, Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Occupational hazards
BENZOPHENONE-1	5	79%	Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
ETHYL ACETATE	4	78%	Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
D&C YELLOW 11 D&C YELLOW NO 11 (CI 47000)	0	75%	none identified
ISOPROPYL ALCOHOL	4	72%	Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
TOSYLAMIDE/ FORMALDEHYDE RESIN	4	72%	Allergies/immunotoxicity
CAMPHOR	4	69%	Violations, restrictions & warnings, Neurotoxicity, Organ system toxicity (non-reproductive), Occupational hazards
FD&C BLUE 1 FD&C BLUE NO 1 (CI 42090)	1	83%	none identified
NITROCELLULOSE	1	94%	Organ system toxicity (non-reproductive)
BUTYL ACETATE	1	78%	Irritation (skin, eyes, or lungs), Occupational hazards

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more in vitro tests on mammalian cells show positive mutation results		ETHYL ACETATE, CAMPHOR
Cancer - not classifiable/not likely to be human carcinogen		DIBUTYL PHTHALATE
Cancer - not classifiable/not likely to be human carcinogen		ISOPROPYL ALCOHOL, FD&C BLUE 1

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Limited evidence of developmental toxicity		ISOPROPYL ALCOHOL
Human nervous system toxicant - moderate evidence		ETHYL ACETATE
Possible human developmental toxicant		DIBUTYL PHTHALATE

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		CAMPHOR
Violation of government restrictions - Banned or found unsafe for use in cosmetics		DIBUTYL PHTHALATE

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study		BUTYL ACETATE
One or more animal studies show brain and nervous system effects at high doses		FD&C BLUE 1
Strong evidence of human neurotoxicity		ETHYL ACETATE
One or more animal studies show brain and nervous system effects at low doses		CAMPHOR
One or more animal studies show brain and nervous system effects at high doses		BENZOPHENONE-1
Strong evidence of human neurotoxicity		ISOPROPYL ALCOHOL, DIBUTYL PHTHALATE

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Human any disruptor - strong evidence		DIBUTYL PHTHALATE, BENZOPHENONE-1

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Human skin toxicant - strong evidence		BENZOPHENONE-1
Known human immune system toxicant		TOSYLAMIDE/ FORMALDEHYDE RESIN, DIBUTYL PHTHALATE

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not suspected to be bioaccumulative		ISOPROPYL ALCOHOL
Persistent, bioaccumulative in wildlife		DIBUTYL PHTHALATE

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Classified as expected to be toxic or harmful		NITROCELLULOSE
Limited evidence of sense organ toxicity		ISOPROPYL ALCOHOL
One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient)		FD&C BLUE 1
Limited evidence of sense organ toxicity		ETHYL ACETATE
One or more animal studies show gastrointestinal effects at low doses		CAMPHOR, BENZOPHENONE-1
Known human respiratory toxicant		DIBUTYL PHTHALATE

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Wildlife and environmental toxicity		DIBUTYL PHTHALATE
Not suspected to be an environmental toxin		NITROCELLULOSE, ISOPROPYL ALCOHOL

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Classified as skin irritant	products for use on skin	BUTYL ACETATE
Classified as irritant		ISOPROPYL ALCOHOL, ETHYL ACETATE

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Insufficient data to determine safety		DIBUTYL PHTHALATE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		ETHYL ACETATE, DIBUTYL PHTHALATE, BENZOPHENONE-1, BUTYL ACETATE
Not assessed for safety in cosmetics by industry panel		NITROCELLULOSE, ISOPROPYL ALCOHOL, CAMPHOR

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to high doses		BUTYL ACETATE
Allowed workplace exposures restricted to moderate doses		DIBUTYL PHTHALATE, CAMPHOR
Allowed workplace exposures restricted to high doses		ETHYL ACETATE, ISOPROPYL ALCOHOL

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		DIBUTYL PHTHALATE