

Compact for Safe Cosmetics
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Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Occupational hazards, Biochemical or cellular level changes |
Ingredients from packaging: Water, Glycerin, Hamamelis Virginiana (Witch Hazel) Water, Glycyrrhiza Uralensis (Licorice) Root Extract (1), Camellia Sinensis (Green Tea) Leaf Extract (1), Ficus Carica (Fig) Fruit Extract (1), Stevia Rebaudiana Extract, Polysorbate 80, Benzoic Acid, Sodium Phosphate, Disodium Phosphate, Sodium Fluoride, Flavor.
Directions from packaging: Use once daily after brushing your teeth with toothpaste. Vigorously swish 10 ml of rinse between your teeth for 1 minute and then spit out. Do not swallow the rinse.
| score | data gap | concerns | |
| SODIUM FLUORIDE | 9 | 63% | Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Neurotoxicity, Endocrine disruption, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Occupational hazards, Biochemical or cellular level changes |
| FICUS CARICA (FIG) EXTRACT FICUS CARICA EXTRACT | 8 | 59% | Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive) |
| FLAVOR | 4 | 100% | Miscellaneous |
| TITANIUM DIOXIDE (NON-NANO) | 1 | 81% | Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards, Biochemical or cellular level changes |
| BENZOIC ACID | 4 | 65% | Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| CARRAGEENAN CHONDRUS CRISPUS | 2 | 75% | Organ system toxicity (non-reproductive), Contamination concerns (DEGRADED CARRAGEENAN), Biochemical or cellular level changes |
| CYCLODEXTRIN | 2 | 84% | Multiple, additive exposure sources |
| SODIUM BICARBONATE | 2 | 80% | none identified |
| HYDRATED SILICA | 2 | 79% | Persistence and bioaccumulation |
| CAMELLIA SINENSIS (GREEN TEA) LEAF EXTRACT CAMELLIA SINENSIS LEAF EXTRACT | 2 | 76% | Violations, restrictions & warnings |
| GLYCERIN | 2 | 74% | Organ system toxicity (non-reproductive), Occupational hazards |
| MELALEUCA ALTERNIFOLIA (TEA TREE) LEAF OIL MELALEUCA ALTERNIFOLIA LEAF OIL | 1 | 93% | Endocrine disruption, Allergies/immunotoxicity |
| TRISODIUM PHOSPHATE | 1 | 88% | none identified |
| GLYCYRRHIZA URALENSIS (LICORICE) ROOT EXTRACT GLYCYRRHIZA URALENSIS ROOT EXTRACT | 1 | 85% | none identified |
| CELLULOSE GUM | 1 | 80% | none identified |
| BAMBUSA ARUNDINACEA (BAMBOO) STEM EXTRACT BAMBUSA ARUNDINACEA STEM EXTRACT | 0 | 100% | none identified |
| CITRUS PARADISI (GRAPEFRUIT) FRUIT EXTRACT CITRUS GRANDIS FRUIT EXTRACT | 0 | 100% | none identified |
| SODIUM METHYL COCOYL TAURATE | 0 | 100% | none identified |
| STEVIA REBAUDIANA (SWEETLEAF) EXTRACT STEVIA REBAUDIANA EXTRACT | 0 | 100% | none identified |
| CALCIUM GLYCEROPHOSPHATE | 0 | 94% | none identified |
| CALCIUM ASCORBATE | 0 | 93% | none identified |
| WATER | 0 | 0% | innocuous |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show tumor formation at high doses | CELLULOSE GUM | |
| One or more in vitro tests non-mammalian cells show positive mutation results | GLYCYRRHIZA URALENSIS (LICORICE) ROOT EXTRACT, TRISODIUM PHOSPHATE | |
| One or more in vitro tests on mammalian cells show positive mutation results | TITANIUM DIOXIDE (NON-NANO), SODIUM BICARBONATE, GLYCERIN | |
| One or more animal studies show tumor formation at low doses | SODIUM FLUORIDE | |
| Not likely to be carcinogenic in humans | CARRAGEENAN, BENZOIC ACID | |
| Cancer - not classifiable/not likely to be human carcinogen | HYDRATED SILICA |
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show reproductive effects at high doses | CYCLODEXTRIN | |
| One or more animal studies show reproductive effects at moderate doses | SODIUM BICARBONATE | |
| Human nervous system toxicant - moderate evidence | SODIUM FLUORIDE | |
| One or more animal studies show reproductive effects at moderate doses | GLYCERIN, CELLULOSE GUM |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | BENZOIC ACID | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | SODIUM FLUORIDE | |
| Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Fragrance subject to restrictions: safe only within recommended use or concentration limitsn) | CAMELLIA SINENSIS (GREEN TEA) LEAF EXTRACT | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in cosmetics (concentration limit) | BENZOIC ACID | |
| Violation of government restrictions - Banned or found unsafe for use in cosmetics | FICUS CARICA (FIG) EXTRACT |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show brain and nervous system effects at high doses | GLYCERIN, SODIUM BICARBONATE | |
| One or more animal studies show brain and nervous system effects at moderate doses | GLYCYRRHIZA URALENSIS (LICORICE) ROOT EXTRACT, BENZOIC ACID, CARRAGEENAN | |
| Strong evidence of human neurotoxicity | SODIUM FLUORIDE |
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show endocrine system disruption at high doses | GLYCERIN | |
| One or more animal studies show endocrine disruption at moderate doses | GLYCYRRHIZA URALENSIS (LICORICE) ROOT EXTRACT | |
| Limited evidence of any disruption | MELALEUCA ALTERNIFOLIA (TEA TREE) LEAF OIL | |
| One or more studies show endocrine system disruption at low doses | SODIUM FLUORIDE |
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Limited evidence of any toxicity | MELALEUCA ALTERNIFOLIA (TEA TREE) LEAF OIL | |
| One or more animal studies show immune effects at low doses | TITANIUM DIOXIDE (NON-NANO) | |
| Known human immune system toxicant | FICUS CARICA (FIG) EXTRACT |
*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not suspected to be bioaccumulative | TITANIUM DIOXIDE (NON-NANO) | |
| Persistent, bioaccumulative in wildlife and humans | HYDRATED SILICA |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient) | CELLULOSE GUM | |
| One or more animal studies show gastrointestinal effects at moderate doses (low dose studies may be unavailable for this ingredient) | GLYCYRRHIZA URALENSIS (LICORICE) ROOT EXTRACT, SODIUM BICARBONATE, TRISODIUM PHOSPHATE | |
| One or more animal studies show sense organ effects at very low doses | products for use around the eyes, mouth, or lips | BENZOIC ACID |
| One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient) | CYCLODEXTRIN | |
| One or more animal studies show gastrointestinal effects at very low doses | SODIUM FLUORIDE, GLYCERIN, CARRAGEENAN, TITANIUM DIOXIDE (NON-NANO) | |
| Known human immune system toxicant | FICUS CARICA (FIG) EXTRACT |
*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Occupational hazards related to handling | SODIUM FLUORIDE | |
| Ingredient not fully labeled - identity unknown | FLAVOR |
*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Designated as safe for general or specific, limited use in food | GLYCYRRHIZA URALENSIS (LICORICE) ROOT EXTRACT, TRISODIUM PHOSPHATE, TITANIUM DIOXIDE (NON-NANO), SODIUM FLUORIDE, SODIUM BICARBONATE, MELALEUCA ALTERNIFOLIA (TEA TREE) LEAF OIL, GLYCERIN, CELLULOSE GUM, CARRAGEENAN, CAMELLIA SINENSIS (GREEN TEA) LEAF EXTRACT, CALCIUM GLYCEROPHOSPHATE, CALCIUM ASCORBATE, BENZOIC ACID | |
| Used in food or as an additive with limited or no toxicity information available | SODIUM FLUORIDE, CYCLODEXTRIN |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show skin irritation at high doses | CYCLODEXTRIN | |
| One or more animal studies show skin irritation at moderate doses | TITANIUM DIOXIDE (NON-NANO), SODIUM BICARBONATE, GLYCERIN | |
| One or more animal studies show skin irritation at low doses | BENZOIC ACID |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | SODIUM BICARBONATE | |
| Safety assessment was based on related chemical | CALCIUM ASCORBATE | |
| Insufficient data to determine safety | BENZOIC ACID | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | CELLULOSE GUM | |
| Not assessed for safety in cosmetics by industry panel | HYDRATED SILICA, GLYCYRRHIZA URALENSIS (LICORICE) ROOT EXTRACT, FLAVOR, TRISODIUM PHOSPHATE, TITANIUM DIOXIDE (NON-NANO), STEVIA REBAUDIANA (SWEETLEAF) EXTRACT, SODIUM METHYL COCOYL TAURATE, MELALEUCA ALTERNIFOLIA (TEA TREE) LEAF OIL, GLYCERIN, FICUS CARICA (FIG) EXTRACT, CYCLODEXTRIN, CITRUS PARADISI (GRAPEFRUIT) FRUIT EXTRACT, CARRAGEENAN, CAMELLIA SINENSIS (GREEN TEA) LEAF EXTRACT, CALCIUM GLYCEROPHOSPHATE, BAMBUSA ARUNDINACEA (BAMBOO) STEM EXTRACT |
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to very low doses | SODIUM FLUORIDE | |
| Allowed workplace exposures restricted to low doses | TITANIUM DIOXIDE (NON-NANO) | |
| Allowed workplace exposures restricted to moderate doses | GLYCERIN |
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | SODIUM BICARBONATE, GLYCERIN | |
| One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood | TITANIUM DIOXIDE (NON-NANO) | |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | CELLULOSE GUM | |
| One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood | SODIUM FLUORIDE, CARRAGEENAN |
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