

Compact for Safe Cosmetics
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Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: Neurotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards |
Ingredients from packaging: RELAXER CREME: WATER (AQUA); PETROLATUM; MINERAL OIL (PARAFFINUM LIQUIDUM); CETEARYL ALCOHOL; BEHENTRIMONIUM METHOSULFATE; PEG-75 LANOLIN; GUANIDINE CARBONATE; POLYQUATERNIUM-6; COCAMIDOPROPYL BETAINE; PROPYLENE GLYCOL; FRAGRANCE (PARFUM); D&C ORANGE NO. 4 (CI 15510); SUCCINIC ACID; DENATONIUM BENZOATE. CREME ACTIVATOR: MINERAL OIL (PARAFFINUM LIQUIDUM); CALCIUM HYDROXIDE; HYDROGENATED BUTYLENE; ETHYLENE; STYRENE COPOLYMER; HYDROGENATED ETHYLENE; PROPYLENE. NEUTRALIZING SHAMPOO: WATER (AQUA); COCAMIDOPROPYL BETAINE; SODIUM LAURETH SULFATE; LAURAMIDE DEA; PROPYLENE GLYCOL; POLYQUATERNIUM-7; FRAGRANCE (PARFUM); CITRIC ACID; METHYLISOTHIAZOLINONE; METHYLCHLOROISOTHIAZOLINONE; PHENOLSULFONPHTHALEIN. CONDITIONING TREATMENT: WATER (AQUA); CETEARYL ALCOHOL; MINERAL OIL (PARAFFINUM LIQUIDUM); DICETYLDIMONIUM CHLORIDE; PEG-40 HYDROGENATED CASTOR OIL; POLYQUATERNIUM-32; CHOLESTEROL; PANTHENOL; TOCOPHERYL ACETATE; ALOE BARBADENSIS; FRAGRANCE (PARFUM); D&C NO. 33 (CI 17200); METHYLISOTHIAZOLINONE; METHYLCHLOROISOTHIAZOLINONE. LEAVE-IN CONDITIONER: WATER (AQUA); POLYQUATERNIUM-22; POLYQUATERNIUM-11; DIMETHICONE COPOLYOL LAURATE; DIMETHICONE COPOLYOL; DMDM HYDANTOIN; PANTHENOL; OLETH-20; SILK AMINO ACIDS; FRAGRANCE (PARFUM); TOCOPHERYL ACETATE; ALOE BARBADENSIS; EXTERNAL D&C VIOLET NO. 2 (CI 60730.
Directions from packaging: Read enclosed directions carefully before use.
Warnings from packaging: Contains alkali. Follow directions carefully to avoid skin and scalp irritation, hair loss, or eye injury. Do not use on bleached hair or hair that has been permed with any products containing Ammonium Thioglycolate or 'natural relaxers' containing metallic salts or Ammonium Bisulfite. Do not use on hair which is breaking, splitting or otherwise damaged. Do not apply to scalp. Do not use if scalp is irritated or injured. If hair has been previously relaxed, apply only to new growth, as described in the directions. If the relaxer causes skin or scalp irritation, rinse out immediately and wash with the shampoo in the kit. If irritation persists or if hair loss occurs, consult a physician. Avoid contact with eyes. Can cause blindness. If relaxer gets into eyes, rinse out immediately and consult a physician. Hair is flammable. Keep away from sparks and open flames at all times. Keep out of reach of children.
| score | data gap | concerns | |
| DMDM HYDANTOIN | 7 | 71% | Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Contamination concerns (FORMALDEHYDE) |
| FRAGRANCE | 8 | 100% | Neurotoxicity, Allergies/immunotoxicity, Miscellaneous |
| PEG-40 HYDROGENATED CASTOR OIL | 4 | 75% | Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE) |
| PEG-75 LANOLIN | 4 | 75% | Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE) |
| EXT D&C VIOLET 2 EXTERNAL D&C VIOLET NO. 2 (CI 60730 | 5 | 73% | Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity |
| METHYLCHLOROISOTHIAZOLINONE | 6 | 63% | Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive) |
| METHYLISOTHIAZOLINONE | 6 | 63% | Violations, restrictions & warnings, Allergies/immunotoxicity |
| D&C ORANGE 4 D&C ORANGE NO. 4 | 2 | 72% | Developmental/reproductive toxicity |
| COCAMIDOPROPYL BETAINE | 5 | 63% | Allergies/immunotoxicity, Contamination concerns (NITROSAMINES) |
| SODIUM LAURETH SULFATE | 4 | 88% | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE) |
| OLETH-20 | 3 | 87% | Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE) |
| TOCOPHERYL ACETATE | 4 | 81% | Allergies/immunotoxicity, Contamination concerns (HYDROQUINONE) |
| D&C RED 33 D&C NO. 33 | 1 | 75% | none identified |
| MINERAL OIL | 2 | 73% | Organ system toxicity (non-reproductive), Occupational hazards |
| PROPYLENE GLYCOL | 4 | 60% | Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption |
| DIMETHICONE | 2 | 74% | Violations, restrictions & warnings |
| CITRIC ACID | 2 | 72% | Violations, restrictions & warnings |
| LAURAMIDE DEA | 3 | 70% | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (NITROSAMINES) |
| PETROLATUM | 2 | 94% | Organ system toxicity (non-reproductive), Contamination concerns (PAHS) |
| POLYQUATERNIUM-32 | 2 | 94% | Persistence and bioaccumulation, Organ system toxicity (non-reproductive) |
| POLYQUATERNIUM-7 | 2 | 93% | Contamination concerns (ACRYLAMIDE) |
| PANTHENOL | 2 | 88% | Multiple, additive exposure sources |
| POLYQUATERNIUM-6 | 2 | 87% | Persistence and bioaccumulation, Organ system toxicity (non-reproductive) |
| CALCIUM HYDROXIDE | 1 | 83% | Occupational hazards |
| SUCCINIC ACID | 2 | 82% | Neurotoxicity, Organ system toxicity (non-reproductive) |
| CHOLESTEROL | 2 | 74% | Persistence and bioaccumulation |
| CETEARYL ALCOHOL | 0 | 93% | none identified |
| DENATONIUM BENZOATE | 1 | 90% | none identified |
| DICETYLDIMONIUM CHLORIDE | 1 | 90% | none identified |
| GUANIDINE CARBONATE | 1 | 89% | none identified |
| PHENOLSULFONPHTHALEIN | 1 | 88% | Organ system toxicity (non-reproductive) |
| ALOE BARBADENSIS (ALOE VERA) | 1 | 72% | none identified |
| BEHENTRIMONIUM METHOSULFATE | 0 | 100% | none identified |
| DIMETHICONE COPOLYOL LAURATE | 0 | 100% | none identified |
| HYDROGENATED BUTYLENE/ ETHYLENE/ STYRENE COPOLYMER | 0 | 100% | none identified |
| HYDROGENATED ETHYLENE/ PROPYLENE/ STYRENE COPOLYMER | 0 | 100% | none identified |
| POLYQUATERNIUM-22 | 0 | 100% | none identified |
| SILK AMINO ACIDS | 0 | 100% | none identified |
| POLYQUATERNIUM-11 | 0 | 93% | none identified |
| WATER | 0 | 0% | innocuous |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show tumor formation at high doses | MINERAL OIL, LAURAMIDE DEA | |
| One or more in vitro tests non-mammalian cells show positive mutation results | PHENOLSULFONPHTHALEIN, METHYLCHLOROISOTHIAZOLINONE, ALOE BARBADENSIS (ALOE VERA), D&C RED 33 | |
| One or more in vitro tests on mammalian cells show positive mutation results | TOCOPHERYL ACETATE, SUCCINIC ACID, PROPYLENE GLYCOL, D&C ORANGE 4, CALCIUM HYDROXIDE | |
| Cancer - limited evidence | EXT D&C VIOLET 2 | |
| Cancer - not classifiable/not likely to be human carcinogen | CHOLESTEROL |
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show reproductive effects at moderate doses | ALOE BARBADENSIS (ALOE VERA) | |
| One or more animal studies show reproductive effects at moderate doses | PROPYLENE GLYCOL, DICETYLDIMONIUM CHLORIDE, CHOLESTEROL | |
| One or more animal studies show reproductive effects at low doses | D&C ORANGE 4 |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | CITRIC ACID | |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | PROPYLENE GLYCOL, PEG-75 LANOLIN, PEG-40 HYDROGENATED CASTOR OIL, METHYLISOTHIAZOLINONE, LAURAMIDE DEA, ALOE BARBADENSIS (ALOE VERA), METHYLCHLOROISOTHIAZOLINONE, EXT D&C VIOLET 2, COCAMIDOPROPYL BETAINE | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | METHYLISOTHIAZOLINONE | |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Color additive approved by FDA for limited uses in cosmetics | D&C RED 33 | |
| Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel | EXT D&C VIOLET 2, DIMETHICONE | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | METHYLCHLOROISOTHIAZOLINONE, DMDM HYDANTOIN, METHYLCHLOROISOTHIAZOLINONE, METHYLISOTHIAZOLINONE, DMDM HYDANTOIN, METHYLCHLOROISOTHIAZOLINONE |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more in vitro tests on mammalian cells demonstrate neurotoxicity | METHYLISOTHIAZOLINONE | |
| One or more animal studies show brain and nervous system effects at high doses | PROPYLENE GLYCOL, CHOLESTEROL | |
| One or more animal studies show brain and nervous system effects at moderate doses | POLYQUATERNIUM-6 | |
| Moderate evidence of human neurotoxicity | FRAGRANCE | |
| One or more animal studies show brain and nervous system effects at moderate doses | DENATONIUM BENZOATE | |
| One or more animal studies show brain and nervous system effects at very low doses | SUCCINIC ACID |
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show endocrine system disruption at high doses | SUCCINIC ACID, CHOLESTEROL |
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Limited evidence of skin and immune system toxicity | PROPYLENE GLYCOL | |
| Human skin toxicant - strong evidence | EXT D&C VIOLET 2, TOCOPHERYL ACETATE | |
| Known human immune system toxicant | METHYLISOTHIAZOLINONE, METHYLCHLOROISOTHIAZOLINONE, FRAGRANCE, DMDM HYDANTOIN, COCAMIDOPROPYL BETAINE |
*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not suspected to be bioaccumulative | POLYQUATERNIUM-6, POLYQUATERNIUM-32, PETROLATUM | |
| Persistent, bioaccumulative in wildlife | CHOLESTEROL |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show metabolic effects at high doses (low dose studies may be unavailable for this ingredient) | PROPYLENE GLYCOL | |
| Classified as expected to be toxic or harmful | PETROLATUM, POLYQUATERNIUM-32 | |
| One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient) | POLYQUATERNIUM-6, D&C ORANGE 4, PANTHENOL, MINERAL OIL, CALCIUM HYDROXIDE, CHOLESTEROL | |
| One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient) | OLETH-20, TOCOPHERYL ACETATE, SODIUM LAURETH SULFATE, GUANIDINE CARBONATE, DMDM HYDANTOIN, CITRIC ACID, LAURAMIDE DEA | |
| Limited evidence of sense organ toxicity | PEG-75 LANOLIN | |
| One or more animal studies show metabolic effects at very low doses | SUCCINIC ACID | |
| Limited evidence of sense organ toxicity | PEG-40 HYDROGENATED CASTOR OIL | |
| One or more animal studies show kidney or renal system effects at very low doses | PHENOLSULFONPHTHALEIN | |
| Possible human immune system toxicant | METHYLCHLOROISOTHIAZOLINONE |
*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Ingredient not fully labeled - identity unknown | FRAGRANCE |
*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Designated as safe for general or specific, limited use in food | PEG-75 LANOLIN, TOCOPHERYL ACETATE, SUCCINIC ACID, PROPYLENE GLYCOL, PETROLATUM, PEG-40 HYDROGENATED CASTOR OIL, DIMETHICONE, MINERAL OIL, LAURAMIDE DEA, CITRIC ACID, CALCIUM HYDROXIDE, ALOE BARBADENSIS (ALOE VERA) | |
| Used in food or as an additive with limited or no toxicity information available | PANTHENOL |
*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Suspected to be an environmental toxin | POLYQUATERNIUM-6 | |
| Not suspected to be an environmental toxin | PETROLATUM | |
| Suspected to be an environmental toxin | POLYQUATERNIUM-32 |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show skin irritation at high doses | CHOLESTEROL | |
| One or more animal studies show skin irritation at moderate doses | MINERAL OIL, CITRIC ACID | |
| One or more animal studies show skin irritation at low doses | OLETH-20 | |
| One or more animal studies show skin irritation at very low doses | LAURAMIDE DEA | |
| Human any irritant - strong evidence | products for use around the eyes, on the skin, or may be aerosolized (airborne) | SODIUM LAURETH SULFATE, DMDM HYDANTOIN |
| Classified as skin irritant | PROPYLENE GLYCOL |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Safety assessment was based on related chemical | PEG-75 LANOLIN | |
| Missing safety data noted by cosmetic industry review | ALOE BARBADENSIS (ALOE VERA) | |
| Safety assessment was based on related chemical | PROPYLENE GLYCOL, OLETH-20 | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | TOCOPHERYL ACETATE, OLETH-20, PEG-75 LANOLIN, SODIUM LAURETH SULFATE, POLYQUATERNIUM-7, POLYQUATERNIUM-11, PANTHENOL, LAURAMIDE DEA, DMDM HYDANTOIN | |
| Not assessed for safety in cosmetics by industry panel | POLYQUATERNIUM-32, POLYQUATERNIUM-6, SUCCINIC ACID, SILK AMINO ACIDS | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | CETEARYL ALCOHOL, CHOLESTEROL, DIMETHICONE | |
| Not assessed for safety in cosmetics by industry panel | POLYQUATERNIUM-22, PHENOLSULFONPHTHALEIN, PETROLATUM, MINERAL OIL, HYDROGENATED ETHYLENE/ PROPYLENE/ STYRENE COPOLYMER, HYDROGENATED BUTYLENE/ ETHYLENE/ STYRENE COPOLYMER, GUANIDINE CARBONATE, FRAGRANCE, DIMETHICONE COPOLYOL LAURATE, DICETYLDIMONIUM CHLORIDE, DENATONIUM BENZOATE, CITRIC ACID, CALCIUM HYDROXIDE, BEHENTRIMONIUM METHOSULFATE |
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to moderate doses | MINERAL OIL, CALCIUM HYDROXIDE |
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | CITRIC ACID | |
| One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood | LAURAMIDE DEA | |
| One or more animal studies show blood sugar changes at high doses where the human health implications are not yet well understood | PROPYLENE GLYCOL, D&C ORANGE 4, CHOLESTEROL |
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