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70% of dandruff/scalp treatments have lower concerns
66% of shampoos have lower concerns




Compact for Safe Cosmetics
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Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: Neurotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards |
Ingredients from packaging: ACTIVE INGREDIENTS: SALICYLIC ACID 2, WATER, SODIUM LAURETH SULFATE, LAURAMIDE DEA, TEA-LAURYL SULFATE, LAURETH-23, HYDROGENATED TALLOWETH-60 MYRISTYL GLYCOL, GLYCOL DISTEARATE, QUATERNIUM-22, LAURETH-4, POTASSIUM COCOYL HYDROLYZED COLLAGEN, DMDM HYDANTOIN, TETRASODIUM EDTA, SODIUM HYDROXIDE, FRAGRANCE, FD&C BLUE NO.1.
Directions from packaging: Massage Ionil PLUS Shampoo into wet hair. Rinse, then apply Ionil PLUS again and massage into a lather. Allow to remain in hair for about 5 minutes before rinsing. For best results, use at least twice a week or as directed by a physician. Do not use soap, detergent or other shampoo on hair before or after using Ionil PLUS .A compatible after-shampoo conditioner is Ionil Rinse.
| score | data gap | concerns | |
| DMDM HYDANTOIN | 7 | 71% | Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Contamination concerns (FORMALDEHYDE) |
| FRAGRANCE | 8 | 100% | Neurotoxicity, Allergies/immunotoxicity, Miscellaneous |
| SALICYLIC ACID (Active Ingredient) | 7 | 66% | Violations, restrictions & warnings, Neurotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Enhanced skin absorption |
| LAURETH-23 | 5 | 83% | Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE) |
| SODIUM LAURETH SULFATE | 4 | 88% | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE) |
| LAURETH-4 | 3 | 96% | Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE) |
| SODIUM HYDROXIDE | 3 | 77% | Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| LAURAMIDE DEA | 3 | 70% | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (NITROSAMINES) |
| POTASSIUM COCOYL HYDROLYZED COLLAGEN | 2 | 88% | Allergies/immunotoxicity |
| FD&C BLUE 1 FD&C BLUE NO.1 | 1 | 83% | none identified |
| TETRASODIUM EDTA | 2 | 81% | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards |
| TRIETHANOLAMINE LAURYL SULFATE TEA-LAURYL SULFATE | 2 | 72% | Organ system toxicity (non-reproductive), Enhanced skin absorption, Contamination concerns (NITROSAMINES) |
| GLYCOL DISTEARATE | 1 | 93% | Multiple, additive exposure sources |
| QUATERNIUM-22 | 1 | 93% | Contamination concerns (3-DIMETHYLAMINOPROPYLAMINE, ETHYLENE CHLOROHYDRIN) |
| HYDROGENATED TALLOWETH-60 MYRISTYL GLYCOL | 0 | 100% | none identified |
| WATER | 0 | 0% | innocuous |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more in vitro tests non-mammalian cells show positive mutation results | LAURETH-23 | |
| One or more animal studies show tumor formation at high doses | LAURAMIDE DEA | |
| One or more in vitro tests on mammalian cells show positive mutation results | SODIUM HYDROXIDE | |
| Cancer - not classifiable/not likely to be human carcinogen | SALICYLIC ACID | |
| Cancer - not classifiable/not likely to be human carcinogen | FD&C BLUE 1 |
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show reproductive effects at moderate doses | SALICYLIC ACID |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | TRIETHANOLAMINE LAURYL SULFATE, SALICYLIC ACID, LAURAMIDE DEA | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in cosmetics (concentration limit) | SALICYLIC ACID, DMDM HYDANTOIN, SALICYLIC ACID, DMDM HYDANTOIN |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show brain and nervous system effects at high doses | FD&C BLUE 1 | |
| One or more animal studies show brain and nervous system effects at low doses | SALICYLIC ACID, LAURETH-23 | |
| One or more animal studies show brain and nervous system effects at very low doses | SODIUM HYDROXIDE | |
| Moderate evidence of human neurotoxicity | FRAGRANCE |
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Human skin toxicant - strong evidence | POTASSIUM COCOYL HYDROLYZED COLLAGEN | |
| Known human immune system toxicant | FRAGRANCE, DMDM HYDANTOIN |
*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not suspected to be bioaccumulative | SODIUM HYDROXIDE | |
| Not suspected to be persistent | LAURETH-23 | |
| Persistent, bioaccumulative in wildlife | SALICYLIC ACID |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Classified as expected to be toxic or harmful | TRIETHANOLAMINE LAURYL SULFATE | |
| One or more animal studies show kidney or renal system effects at moderate doses (low dose studies may be unavailable for this ingredient) | TETRASODIUM EDTA, | |
| One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient) | FD&C BLUE 1 | |
| One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient) | SODIUM LAURETH SULFATE, DMDM HYDANTOIN, LAURAMIDE DEA | |
| One or more animal studies show metabolic effects at low doses | SALICYLIC ACID, LAURETH-23 | |
| One or more animal studies show metabolic effects at very low doses | SODIUM HYDROXIDE |
*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Occupational hazards related to handling | SODIUM HYDROXIDE | |
| Ingredient not fully labeled - identity unknown | FRAGRANCE |
*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Designated as safe for general or specific, limited use in food | TETRASODIUM EDTA, SODIUM HYDROXIDE, SALICYLIC ACID, LAURETH-23, LAURAMIDE DEA, FD&C BLUE 1 | |
| Used in food or as an additive with limited or no toxicity information available | SALICYLIC ACID, GLYCOL DISTEARATE |
*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Suspected to be an environmental toxin | LAURETH-23 | |
| Not suspected to be an environmental toxin | SODIUM HYDROXIDE |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show skin irritation at high doses | TRIETHANOLAMINE LAURYL SULFATE | |
| One or more animal studies show skin irritation at moderate doses | SALICYLIC ACID | |
| One or more animal studies show skin irritation at low doses | TETRASODIUM EDTA | |
| One or more animal studies show skin irritation at very low doses | SODIUM HYDROXIDE, LAURAMIDE DEA | |
| Human any irritant - strong evidence | products for use around the eyes, on the skin, or may be aerosolized (airborne) | SODIUM LAURETH SULFATE, LAURETH-4, LAURETH-23, DMDM HYDANTOIN |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Safety assessment was based on related chemical | LAURETH-4, LAURETH-23 | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | TETRASODIUM EDTA, QUATERNIUM-22, LAURETH-4, SODIUM LAURETH SULFATE, LAURAMIDE DEA, LAURETH-23, GLYCOL DISTEARATE | |
| Not assessed for safety in cosmetics by industry panel | FRAGRANCE, SODIUM HYDROXIDE, HYDROGENATED TALLOWETH-60 MYRISTYL GLYCOL | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | DMDM HYDANTOIN |
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| No workplace limits set | SODIUM HYDROXIDE | |
| Allowed workplace exposures restricted to low doses | TETRASODIUM EDTA |
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood | LAURETH-23, LAURAMIDE DEA |
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