

Compact for Safe Cosmetics
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Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: Neurotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes |
Ingredients from packaging: CATIONIC CELLULOSE DERIVATIVE POLYMER, CELLULOSIC VISCOSIFIER, POLYVINYL ALCOHOL, DERIVATIZED POLYETHYLENE GLYCOL, CHLORHEXIDINE GLUCONATE (0.003%), POLYAMINOPROPYL BIGUANIDE, EDETATE DISODIUM (0.05%), ALKYL ETHER SULFATE, ETHOXYLATED ALKYL PHENOL, TRIQUATERNARY COCA-BASED PHOSPHOLIPID, SILICA GEL, TITANIUM DIOXIDE.
Directions from packaging: Store solutions at room temperature.
Warnings from packaging: To avoid contamination, never touch dropper tips of the containers with your hands or to any surface. Keep bottles tightly closed when not in use. Contraindications :Do not use any solutions if you are allergic to any ingredient in these products. Not for use with soft (hydrophilic) Contact Lenses.Discard the conditioning solution ninety (90) days after opening. Record date opened in the space provided on bottle label.Avoid Freezing. Important : All gas permeable lens solutions are not the same.Use only the solutions recommended by your doctor.
| score | data gap | concerns | |
| POLYETHYLENE GLYCOL | 5 | 69% | Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE) |
| CHLORHEXIDINE DIGLUCONATE CHLORHEXIDINE GLUCONATE | 5 | 72% | Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| TITANIUM DIOXIDE (NON-NANO) | 1 | 81% | Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards, Biochemical or cellular level changes |
| DISODIUM EDTA EDETATE DISODIUM | 3 | 78% | Neurotoxicity, Organ system toxicity (non-reproductive), Enhanced skin absorption |
| HYDRATED SILICA SILICA GEL | 2 | 79% | Persistence and bioaccumulation |
| POLYAMINOPROPYL BIGUANIDE | 2 | 76% | Violations, restrictions & warnings |
| POLYVINYL ALCOHOL | 1 | 79% | none identified |
| PHOSPHOLIPIDS TRIQUATERNARY COCA-BASED PHOSPHOLIPID | 0 | 100% | none identified |
| SODIUM C12-13 PARETH SULFATE ALKYL ETHER SULFATE | 0 | 100% | none identified |
| ETHOXYLATED ALKYL PHENOL | 0 | 100% | none identified |
| CELLULOSE | 0 | 0% | innocuous |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more in vitro tests non-mammalian cells show positive mutation results | POLYETHYLENE GLYCOL, CHLORHEXIDINE DIGLUCONATE | |
| One or more in vitro tests on mammalian cells show positive mutation results | TITANIUM DIOXIDE (NON-NANO), POLYVINYL ALCOHOL, DISODIUM EDTA | |
| Cancer - not classifiable/not likely to be human carcinogen | HYDRATED SILICA |
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show reproductive effects at high doses | POLYVINYL ALCOHOL, DISODIUM EDTA | |
| One or more animal studies show reproductive effects at moderate doses | POLYETHYLENE GLYCOL |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | POLYETHYLENE GLYCOL, CHLORHEXIDINE DIGLUCONATE | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | CHLORHEXIDINE DIGLUCONATE, CHLORHEXIDINE DIGLUCONATE, POLYAMINOPROPYL BIGUANIDE |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show brain and nervous system effects at high doses | DISODIUM EDTA, CHLORHEXIDINE DIGLUCONATE | |
| One or more animal studies show brain and nervous system effects at moderate doses | POLYVINYL ALCOHOL |
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show endocrine system disruption at high doses | DISODIUM EDTA |
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show immune effects at low doses | TITANIUM DIOXIDE (NON-NANO) | |
| Human immune system toxicant - moderate evidence | CHLORHEXIDINE DIGLUCONATE |
*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not suspected to be bioaccumulative | TITANIUM DIOXIDE (NON-NANO), POLYETHYLENE GLYCOL | |
| Persistent, bioaccumulative in wildlife and humans | HYDRATED SILICA |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient) | POLYVINYL ALCOHOL, POLYETHYLENE GLYCOL, CHLORHEXIDINE DIGLUCONATE | |
| One or more animal studies show broad systemic effects at low doses | DISODIUM EDTA | |
| One or more animal studies show cardiovascular effects at very low doses | TITANIUM DIOXIDE (NON-NANO) |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show skin irritation at moderate doses | TITANIUM DIOXIDE (NON-NANO), POLYETHYLENE GLYCOL | |
| Human skin irritant - moderate evidence | CHLORHEXIDINE DIGLUCONATE |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | POLYVINYL ALCOHOL, DISODIUM EDTA | |
| Not assessed for safety in cosmetics by industry panel | SODIUM C12-13 PARETH SULFATE, ETHOXYLATED ALKYL PHENOL, TITANIUM DIOXIDE (NON-NANO), HYDRATED SILICA, POLYETHYLENE GLYCOL, POLYAMINOPROPYL BIGUANIDE, PHOSPHOLIPIDS |
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to moderate doses | CELLULOSE, TITANIUM DIOXIDE (NON-NANO) |
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | POLYVINYL ALCOHOL | |
| One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood | TITANIUM DIOXIDE (NON-NANO) |
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