Avon ANEW RETINOL EYELINER (2007 formulation) || Skin Deep: Cosmetic Safety Reviews

AVON ANEW RETINOL EYELINER (2007 FORMULATION)

last updated: 12/01/07 brand: Avon by Avon Products, Inc.

SCORE

moderate hazard (out of 10)

89%

data gap

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37% of eye liners have lower concerns

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company does not test on animals.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Contamination concerns, Occupational hazards, Biochemical or cellular level changes

Ingredients from packaging: CYCLOPENTASILOXANE, TOCOPHEROL, CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL, ASCORBYL PALMITATE, ALOE BARBADENSIS LEAF EXTRACT, COCOS NUCIFERA (COCONUT) FRUIT JUICE, RETINYL PALMITATE, OLEA EUROPAEA (OLIVE) LEAF EXTRACT, HYDROLYZED WHEAT PROTEIN, MANNITOL, GLYCOGEN, PARAFFIN, DAUCUS CAROTA SATIVA (CARROT) ROOT EXTRACT, AESCULUS HIPPOCASTANUM (HORSE CHESTNUT) SEED EXTRACT, BIOTIN, CALCIUM PANTOTHENATE, FOENICULUM VULGARE (FENNEL) SEED EXTRACT, MEDICAGO SATIVA (ALFALFA) EXTRACT, PADINA PAVONICA EXTRACT, PANAX GINSENG ROOT EXTRACT, PEG-40 HYDROGENATED CASTOR OIL, PUNICA GRANATUM EXTRACT, C11-12 ISOPARAFFIN, TILIA CORDATA WOOD EXTRACT, YEAST EXTRACT, CHROMIUM OXIDE GREENS, IRON OXIDES, CHROMIUM HYDROXIDE GREEN, FERRIC FERROCYANIDE, TITANIUM DIOXIDE, MICA, CARMINE, ULTRAMARINES, POLYBUTENE, HYDROGENATED COTTONSEED OIL, SIMMONDSIA CHINENSIS (JOJOBA) SEED OIL, CERESIN, OZOKERITE, MICROCRYSTALLINE WAX

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ingredients

	score	data gap	concerns
HYDROGENATED COTTONSEED OIL	8	75%	Contamination concerns (MERCURY, ARSENIC, LEAD, GOSSYPOL, PESTICIDES, PCBS)
PEG-40 HYDROGENATED CASTOR OIL	4	75%	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
RETINYL PALMITATE	5	68%	Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
TITANIUM DIOXIDE (NON-NANO)	1	81%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards, Biochemical or cellular level changes
CHROMIUM OXIDE GREENS	3	86%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Enhanced skin absorption, Occupational hazards
CYCLOPENTASILOXANE	2	79%	Persistence and bioaccumulation
FERRIC FERROCYANIDE	3	76%	Organ system toxicity (non-reproductive), Occupational hazards
MICA	3	75%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Occupational hazards
ULTRAMARINES	2	90%	Multiple, additive exposure sources
AESCULUS HIPPOCASTANUM (HORSE CHESTNUT) SEED EXTRACT	2	88%	Neurotoxicity, Organ system toxicity (non-reproductive)
TOCOPHEROL	2	87%	Contamination concerns (HYDROQUINONE)
IRON OXIDES	2	85%	Persistence and bioaccumulation, Enhanced skin absorption
CHROMIUM HYDROXIDE GREEN	1	84%	Persistence and bioaccumulation
BIOTIN	2	82%	Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive)
PARAFFIN	2	80%	Organ system toxicity (non-reproductive), Occupational hazards
HYDROLYZED WHEAT PROTEIN	1	95%	Allergies/immunotoxicity
CARMINE	0	94%	none identified
CERESIN	0	93%	none identified
MICROCRYSTALLINE WAX (CERA MICROCRISTALLINA)	1	93%	Organ system toxicity (non-reproductive)
MANNITOL	1	92%	none identified
POLYBUTENE	1	92%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
OZOKERITE	1	91%	none identified
PANAX GINSENG (GINSENG) ROOT EXTRACT PANAX GINSENG ROOT EXTRACT	1	91%	none identified
YEAST EXTRACT	1	90%	none identified
ASCORBYL PALMITATE (VITAMIN C PALMITATE)	1	88%	none identified
GLYCOGEN	1	88%	none identified
SIMMONDSIA CHINENSIS (JOJOBA) SEED WAX SIMMONDSIA CHINENSIS (JOJOBA) SEED OIL	1	88%	none identified
CALCIUM PANTOTHENATE	1	87%	none identified
CARTHAMNUS TINCTORIUS (SAFFLOWER) OIL CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL	1	84%	none identified
ALOE BARBADENSIS (ALOE VERA) LEAF EXTRACT ALOE BARBADENSIS LEAF EXTRACT	1	75%	none identified
C11-12 ISOPARAFFIN	0	100%	none identified
DAUCUS CAROTA SATIVA (CARROT) ROOT EXTRACT	0	100%	none identified
FOENICULUM VULGARE (FENNEL) FRUIT EXTRACT FOENICULUM VULGARE (FENNEL) SEED EXTRACT	0	100%	none identified
MEDICAGO SATIVA (ALFALFA) EXTRACT	0	100%	none identified
OLEA EUROPAEA (OLIVE) LEAF EXTRACT	0	100%	none identified
PADINA PAVONICA (PEACOCKS TAIL) EXTRACT PADINA PAVONICA EXTRACT	0	100%	none identified
TILIA CORDATA (LINDEN) WOOD EXTRACT TILIA CORDATA WOOD EXTRACT	0	100%	none identified
PUNICA GRANATUM (POMEGRANATE) EXTRACT PUNICA GRANATUM EXTRACT	0	100%	none identified
COCOS NUCIFERA (COCONUT) FRUIT JUICE	0	100%	none identified

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show tumor formation at moderate doses		PARAFFIN,
One or more animal studies show tumor formation at moderate doses		CYCLOPENTASILOXANE
One or more animal studies show tumor formation at high doses		CARTHAMNUS TINCTORIUS (SAFFLOWER) OIL
One or more in vitro tests on mammalian cells show positive mutation results		TOCOPHEROL, TITANIUM DIOXIDE (NON-NANO), MANNITOL
Cancer - limited evidence		RETINYL PALMITATE
Cancer - not classifiable/not likely to be human carcinogen		CHROMIUM HYDROXIDE GREEN, CHROMIUM OXIDE GREENS

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive effects at moderate doses		GLYCOGEN
One or more animal studies show reproductive effects at low doses		RETINYL PALMITATE, BIOTIN

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		RETINYL PALMITATE
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		ALOE BARBADENSIS (ALOE VERA) LEAF EXTRACT, PEG-40 HYDROGENATED CASTOR OIL, HYDROGENATED COTTONSEED OIL

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show brain and nervous system effects at high doses		YEAST EXTRACT, ULTRAMARINES, RETINYL PALMITATE
One or more animal studies show brain and nervous system effects at moderate doses		FERRIC FERROCYANIDE, CALCIUM PANTOTHENATE,
One or more animal studies show any effects at moderate doses		CYCLOPENTASILOXANE
One or more animal studies show brain and nervous system effects at low doses		BIOTIN, AESCULUS HIPPOCASTANUM (HORSE CHESTNUT) SEED EXTRACT

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show endocrine disruption at moderate doses		CYCLOPENTASILOXANE

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show gastrointestinal effects at moderate doses		MICA
One or more human case studies show possible skin allergy effects		HYDROLYZED WHEAT PROTEIN
One or more animal studies show immune effects at low doses		TITANIUM DIOXIDE (NON-NANO)

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not suspected to be bioaccumulative		TITANIUM DIOXIDE (NON-NANO), POLYBUTENE, MICROCRYSTALLINE WAX (CERA MICROCRISTALLINA), CHROMIUM OXIDE GREENS
Persistent, bioaccumulative in wildlife		CYCLOPENTASILOXANE, CHROMIUM HYDROXIDE GREEN
Persistent, bioaccumulative in wildlife and humans		IRON OXIDES, MICA

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Limited evidence of skin toxicity		RETINYL PALMITATE
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		CALCIUM PANTOTHENATE
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient)		PANAX GINSENG (GINSENG) ROOT EXTRACT,
One or more animal studies show sense organ effects at high doses (low dose studies may be unavailable for this ingredient)	products for use around the eyes, mouth, or lips	YEAST EXTRACT
One or more animal studies show kidney or renal system effects at high doses (low dose studies may be unavailable for this ingredient)		SIMMONDSIA CHINENSIS (JOJOBA) SEED WAX, ULTRAMARINES, ASCORBYL PALMITATE (VITAMIN C PALMITATE)
One or more animal studies show sense organ effects at moderate doses (low dose studies may be unavailable for this ingredient)	products for use around the eyes, mouth, or lips	PARAFFIN, CYCLOPENTASILOXANE, OZOKERITE
One or more animal studies show no adverse any effects at high doses		CHROMIUM HYDROXIDE GREEN
Classified as expected to be toxic or harmful		MICROCRYSTALLINE WAX (CERA MICROCRISTALLINA), POLYBUTENE
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		CHROMIUM OXIDE GREENS,
One or more animal studies show sense organ effects at moderate doses (low dose studies may be unavailable for this ingredient)	products for use around the eyes, mouth, or lips	CARTHAMNUS TINCTORIUS (SAFFLOWER) OIL
One or more animal studies show blood effects at low doses		BIOTIN
Limited evidence of sense organ toxicity		PEG-40 HYDROGENATED CASTOR OIL
One or more animal studies show broad systemic effects at very low doses		AESCULUS HIPPOCASTANUM (HORSE CHESTNUT) SEED EXTRACT, TITANIUM DIOXIDE (NON-NANO)
Known human respiratory toxicant		FERRIC FERROCYANIDE
Possible human respiratory toxicant		MICA

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Designated as safe for general or specific, limited use in food		TOCOPHEROL, YEAST EXTRACT, TITANIUM DIOXIDE (NON-NANO), TILIA CORDATA (LINDEN) WOOD EXTRACT, IRON OXIDES, RETINYL PALMITATE, PEG-40 HYDROGENATED CASTOR OIL, PARAFFIN, MEDICAGO SATIVA (ALFALFA) EXTRACT, MANNITOL, FOENICULUM VULGARE (FENNEL) FRUIT EXTRACT, CARMINE, CALCIUM PANTOTHENATE, BIOTIN, ASCORBYL PALMITATE (VITAMIN C PALMITATE)
Used in food or as an additive with limited or no toxicity information available		ULTRAMARINES

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Suspected to be an environmental toxin		CHROMIUM OXIDE GREENS
Not suspected to be an environmental toxin		POLYBUTENE, TITANIUM DIOXIDE (NON-NANO), MICROCRYSTALLINE WAX (CERA MICROCRISTALLINA)

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show skin irritation at moderate doses		TITANIUM DIOXIDE (NON-NANO), PARAFFIN, OZOKERITE, CYCLOPENTASILOXANE, CARTHAMNUS TINCTORIUS (SAFFLOWER) OIL
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	POLYBUTENE

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Missing safety data noted by cosmetic industry review		ALOE BARBADENSIS (ALOE VERA) LEAF EXTRACT
Pesticide inert of potential toxicological concern		POLYBUTENE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		POLYBUTENE, TOCOPHEROL, RETINYL PALMITATE, PARAFFIN, OZOKERITE, MICROCRYSTALLINE WAX (CERA MICROCRISTALLINA), CERESIN, CARTHAMNUS TINCTORIUS (SAFFLOWER) OIL, BIOTIN, ASCORBYL PALMITATE (VITAMIN C PALMITATE)
Not assessed for safety in cosmetics by industry panel		SIMMONDSIA CHINENSIS (JOJOBA) SEED WAX, COCOS NUCIFERA (COCONUT) FRUIT JUICE, PUNICA GRANATUM (POMEGRANATE) EXTRACT, TITANIUM DIOXIDE (NON-NANO), YEAST EXTRACT, TILIA CORDATA (LINDEN) WOOD EXTRACT, PANAX GINSENG (GINSENG) ROOT EXTRACT, PADINA PAVONICA (PEACOCKS TAIL) EXTRACT, OLEA EUROPAEA (OLIVE) LEAF EXTRACT, MEDICAGO SATIVA (ALFALFA) EXTRACT, MANNITOL, HYDROLYZED WHEAT PROTEIN, GLYCOGEN, FOENICULUM VULGARE (FENNEL) FRUIT EXTRACT, DAUCUS CAROTA SATIVA (CARROT) ROOT EXTRACT, CYCLOPENTASILOXANE, CHROMIUM OXIDE GREENS, CHROMIUM HYDROXIDE GREEN, CALCIUM PANTOTHENATE, C11-12 ISOPARAFFIN, AESCULUS HIPPOCASTANUM (HORSE CHESTNUT) SEED EXTRACT

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to low doses		PARAFFIN, MICA, FERRIC FERROCYANIDE, CHROMIUM OXIDE GREENS,
Allowed workplace exposures restricted to low doses		TITANIUM DIOXIDE (NON-NANO)

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Produces excess reactive oxygen species that can interfere with cellular signaling, cause mutations, lead to cell death and may be implicated in cardiovascular disease.		RETINYL PALMITATE
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		SIMMONDSIA CHINENSIS (JOJOBA) SEED WAX, PANAX GINSENG (GINSENG) ROOT EXTRACT, CYCLOPENTASILOXANE, AESCULUS HIPPOCASTANUM (HORSE CHESTNUT) SEED EXTRACT
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood		TITANIUM DIOXIDE (NON-NANO)