PRESCRIPTIVES BEYOND LONG MAXIMUM LENGTH MASCARA (2007 formulation) || Skin Deep: Cosmetic Safety Reviews

PRESCRIPTIVES BEYOND LONG MAXIMUM LENGTH MASCARA (2007 FORMULATION)

last updated: 12/01/07 brand: Prescriptives by Estée Lauder

SCORE

high hazard (out of 10)

79%

data gap

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COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company does not test on animals.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes

Note: This product formulation was confirmed with the FDA VCRD.

Ingredients from packaging: WATER, PANTETHINE, SODIUM HYALURONATE, PANTHENOL, ACACIA SENEGAL GUM, UREA, PROPYLENE GLYCOL, DIMETHICONE PEG-8 POLYACRYLATE, PVP, SIMETHICONE, ISOSTEARIC ACID, COPERNICIA CERIFERA (CARNAUBA) WAX, HYDROXYETHYLCELLULOSE, ACRYLATES/OCTYLACRYLAMIDE COPOLYMER, POLYVINYL ACETATE, DISODIUM EDTA, BHT, BENZYL ALCOHOL, PHENOXYETHANOL, METHYLPARABEN, ETHYLPARABEN, PROPYLPARABEN, STEARIC ACID, BUTYLPARABEN, ISOBUTYLPARABEN, MICA, IRON OXIDES, TITANIUM DIOXIDE, FERRIC FERROCYANIDE, ULTRAMARINES, BLUE 1 LAKE (LABEL ABBREVIATION), BRONZE POWDER, ALUMINUM POWDER, GLYCERYL STEARATE, BISMUTH OXYCHLORIDE, CARMINE, CHROMIUM HYDROXIDE GREEN, CHROMIUM OXIDE GREENS, YELLOW 5 LAKE (LABEL ABBREVIATION), POLYISOBUTENE, SILICA, ACRYLATES COPOLYMER, AMINOMETHYL PROPANEDIOL, VP/EICOSENE COPOLYMER

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ingredients

	score	data gap	concerns
METHYLPARABEN	10	63%	Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes
ALUMINUM POWDER	7	82%	Cancer, Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive), Enhanced skin absorption, Occupational hazards
SILICA	1	69%	Biochemical or cellular level changes
BUTYLPARABEN	6	79%	Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
DIMETHICONE PEG-8 POLYACRYLATE	4	76%	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
BENZYL ALCOHOL	6	64%	Violations, restrictions & warnings, Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
BHT	6	61%	Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards, Biochemical or cellular level changes
POLYVINYL ACETATE	5	91%	Organ system toxicity (non-reproductive), Contamination concerns (ARSENIC, HEAVY METALS)
ETHYLPARABEN	5	80%	Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
PROPYLPARABEN	5	71%	Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
FD&C BLUE 1 ALUMINUM LAKE BLUE 1 LAKE (LABEL ABBREVIATION)	4	91%	Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive)
FD&C YELLOW 5 ALUMINUM LAKE YELLOW 5 LAKE (LABEL ABBREVIATION)	4	91%	Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive)
TITANIUM DIOXIDE (NON-NANO)	1	81%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards, Biochemical or cellular level changes
BRONZE POWDER	4	79%	Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Occupational hazards, Biochemical or cellular level changes
ACACIA SENEGAL GUM	4	69%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
PHENOXYETHANOL	4	67%	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
UREA	4	67%	Violations, restrictions & warnings, Irritation (skin, eyes, or lungs), Enhanced skin absorption
PROPYLENE GLYCOL	4	60%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
CHROMIUM OXIDE GREENS	3	86%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Enhanced skin absorption, Occupational hazards
ISOBUTYLPARABEN	3	83%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
DISODIUM EDTA	3	78%	Neurotoxicity, Organ system toxicity (non-reproductive), Enhanced skin absorption
FERRIC FERROCYANIDE	3	76%	Organ system toxicity (non-reproductive), Occupational hazards
ACRYLATES COPOLYMER	3	75%	Contamination concerns (METHACRYLIC ACID, ACRYLIC ACID, 2-ETHYLHEXYL ACRYLATE)
MICA	3	75%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Occupational hazards
ULTRAMARINES	2	90%	Multiple, additive exposure sources
PANTHENOL	2	88%	Multiple, additive exposure sources
IRON OXIDES	2	85%	Persistence and bioaccumulation, Enhanced skin absorption
CHROMIUM HYDROXIDE GREEN	1	84%	Persistence and bioaccumulation
STEARIC ACID	2	74%	Neurotoxicity, Irritation (skin, eyes, or lungs)
AMINOMETHYL PROPANEDIOL	2	72%	Organ system toxicity (non-reproductive), Contamination concerns (NITROSAMINES, OXAZOLIDINE)
CARMINE	0	94%	none identified
POLYISOBUTENE	1	94%	Organ system toxicity (non-reproductive)
ISOSTEARIC ACID	0	93%	none identified
BISMUTH OXYCHLORIDE	1	89%	none identified
GLYCERYL MONOSTEARATE GLYCERYL STEARATE	1	88%	none identified
PANTETHINE	1	87%	none identified
SODIUM HYALURONATE	1	83%	none identified
HYDROXYETHYLCELLULOSE	1	82%	none identified
PVP	1	81%	Organ system toxicity (non-reproductive)
ACRYLATES/ OCTYLACRYLAMIDE COPOLYMER	0	100%	none identified
SIMETHICONE	0	100%	none identified
VP/ EICOSENE COPOLYMER	0	94%	none identified
COPERNICIA CERIFERA (CARNAUBA) WAX	0	93%	none identified
WATER	0	0%	innocuous

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more in vitro tests non-mammalian cells show positive mutation results		PHENOXYETHANOL
One or more in vitro tests on mammalian cells show positive mutation results		ACACIA SENEGAL GUM, UREA, TITANIUM DIOXIDE (NON-NANO), PROPYLPARABEN, PROPYLENE GLYCOL, METHYLPARABEN, ETHYLPARABEN, DISODIUM EDTA, BUTYLPARABEN, BENZYL ALCOHOL
Cancer - moderate evidence - cardiovascular and cancer		BRONZE POWDER
Cancer - strong evidence		ALUMINUM POWDER
Not likely to be carcinogenic in humans		STEARIC ACID
Cancer - not classifiable/not likely to be human carcinogen		CHROMIUM HYDROXIDE GREEN, PVP, POLYVINYL ACETATE, CHROMIUM OXIDE GREENS, BHT

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive effects at high doses		ACACIA SENEGAL GUM, UREA, HYDROXYETHYLCELLULOSE, ETHYLPARABEN, DISODIUM EDTA, BHT, BENZYL ALCOHOL
One or more animal studies show reproductive effects at moderate doses		SODIUM HYALURONATE, PROPYLENE GLYCOL, PANTETHINE
One or more animal studies show any effects at low doses		PROPYLPARABEN
One or more animal studies show reproductive effects at very low doses		BRONZE POWDER,
One or more animal studies show any effects at very low doses		BUTYLPARABEN
Human nervous system toxicant - moderate evidence		FD&C YELLOW 5 ALUMINUM LAKE, FD&C BLUE 1 ALUMINUM LAKE, ALUMINUM POWDER

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		PROPYLENE GLYCOL, DIMETHICONE PEG-8 POLYACRYLATE, BENZYL ALCOHOL, AMINOMETHYL PROPANEDIOL, ACRYLATES COPOLYMER
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel		BENZYL ALCOHOL
Determined safe for use in cosmetics, subject to concentration or use limitations - Restrictions on impurities recommended by industry safety panel		ACACIA SENEGAL GUM
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		UREA
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Fragrance subject to restrictions: safe only within recommended use or concentration limitsn)		BENZYL ALCOHOL
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in cosmetics (concentration limit)		PHENOXYETHANOL
Violation of government restrictions - Banned or found unsafe for use in cosmetics		METHYLPARABEN

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show brain and nervous system effects at high doses		ULTRAMARINES, PROPYLENE GLYCOL, HYDROXYETHYLCELLULOSE
One or more animal studies show brain and nervous system effects at moderate doses		UREA, SODIUM HYALURONATE
One or more animal studies show brain and nervous system effects at low doses		DISODIUM EDTA
One or more animal studies show brain and nervous system effects at moderate doses		PHENOXYETHANOL, METHYLPARABEN, FERRIC FERROCYANIDE, AMINOMETHYL PROPANEDIOL
One or more animal studies show brain and nervous system effects at low doses		BHT
One or more animal studies show brain and nervous system effects at very low doses		STEARIC ACID
Strong evidence of human neurotoxicity		FD&C YELLOW 5 ALUMINUM LAKE, FD&C BLUE 1 ALUMINUM LAKE, BENZYL ALCOHOL, ALUMINUM POWDER

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Human any disruptor - strong evidence		PROPYLPARABEN
One or more animal studies show endocrine disruption at moderate doses		ISOBUTYLPARABEN
One or more animal studies show endocrine system disruption at high doses		BHT, DISODIUM EDTA, PVP
Human any disruptor - strong evidence		METHYLPARABEN, BUTYLPARABEN, ETHYLPARABEN

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show gastrointestinal effects at moderate doses		MICA
One or more human case studies show possible allergenic effects		BENZYL ALCOHOL
Limited evidence of skin and immune system toxicity		PHENOXYETHANOL
Human skin toxicant - strong evidence		ACACIA SENEGAL GUM
One or more animal studies show immune effects at low doses		TITANIUM DIOXIDE (NON-NANO)
Limited evidence of skin and immune system toxicity		PROPYLENE GLYCOL
Human skin toxicant - strong evidence		PROPYLPARABEN, METHYLPARABEN, ISOBUTYLPARABEN, ETHYLPARABEN, BUTYLPARABEN
Known human immune system toxicant		BHT

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not suspected to be bioaccumulative		TITANIUM DIOXIDE (NON-NANO), PVP, POLYVINYL ACETATE, POLYISOBUTENE, CHROMIUM OXIDE GREENS, BRONZE POWDER
Persistent, bioaccumulative in wildlife		CHROMIUM HYDROXIDE GREEN
Persistent, bioaccumulative in wildlife and humans		IRON OXIDES, MICA

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Classified as expected to be toxic or harmful		POLYVINYL ACETATE, POLYISOBUTENE
One or more animal studies show no adverse any effects at high doses		CHROMIUM HYDROXIDE GREEN
One or more animal studies show metabolic effects at high doses (low dose studies may be unavailable for this ingredient)		BENZYL ALCOHOL, ULTRAMARINES, HYDROXYETHYLCELLULOSE, STEARIC ACID, PANTHENOL, PANTETHINE
One or more animal studies show sense organ effects at moderate doses (low dose studies may be unavailable for this ingredient)	products for use around the eyes, mouth, or lips	SODIUM HYALURONATE
One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient)		BISMUTH OXYCHLORIDE
One or more animal studies show sense organ effects at moderate doses (low dose studies may be unavailable for this ingredient)	products for use around the eyes, mouth, or lips	SILICA, PROPYLENE GLYCOL
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		GLYCERYL MONOSTEARATE, PVP, UREA, CHROMIUM OXIDE GREENS
Limited evidence of sense organ toxicity		PROPYLPARABEN, ISOBUTYLPARABEN, ETHYLPARABEN, DIMETHICONE PEG-8 POLYACRYLATE, BUTYLPARABEN, FD&C YELLOW 5 ALUMINUM LAKE, FD&C BLUE 1 ALUMINUM LAKE
One or more animal studies show broad systemic effects at low doses		DISODIUM EDTA, AMINOMETHYL PROPANEDIOL, BHT
One or more animal studies show sense organ effects at very low doses	products for use around the eyes, mouth, or lips	ACACIA SENEGAL GUM
One or more animal studies show cardiovascular effects at very low doses		TITANIUM DIOXIDE (NON-NANO),
One or more animal studies show sense organ effects at very low doses	products for use around the eyes, mouth, or lips	PHENOXYETHANOL
Possible human respiratory toxicant		MICA, ALUMINUM POWDER
Known human hematologic toxicant		BRONZE POWDER
Known human respiratory toxicant		FERRIC FERROCYANIDE, METHYLPARABEN

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Designated as safe for general or specific, limited use in food		ACACIA SENEGAL GUM, UREA, TITANIUM DIOXIDE (NON-NANO), IRON OXIDES, STEARIC ACID, PVP, PROPYLPARABEN, PROPYLENE GLYCOL, POLYVINYL ACETATE, POLYISOBUTENE, METHYLPARABEN, GLYCERYL MONOSTEARATE, FD&C BLUE 1 ALUMINUM LAKE, DISODIUM EDTA, DIMETHICONE PEG-8 POLYACRYLATE, COPERNICIA CERIFERA (CARNAUBA) WAX, CARMINE, BUTYLPARABEN, BRONZE POWDER, BHT, BENZYL ALCOHOL
Used in food or as an additive with limited or no toxicity information available		ULTRAMARINES, PANTHENOL

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Suspected to be an environmental toxin		CHROMIUM OXIDE GREENS
Not suspected to be an environmental toxin		TITANIUM DIOXIDE (NON-NANO), PVP, POLYVINYL ACETATE, POLYISOBUTENE
Wildlife and environmental toxicity		BRONZE POWDER, PROPYLPARABEN

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show skin irritation at moderate doses		TITANIUM DIOXIDE (NON-NANO), SODIUM HYALURONATE, BUTYLPARABEN
One or more animal studies show skin irritation at low doses		UREA, STEARIC ACID, METHYLPARABEN, BHT, BENZYL ALCOHOL
Classified as skin irritant		PROPYLENE GLYCOL, PHENOXYETHANOL

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Safety assessment was based on related chemical		ISOBUTYLPARABEN
Insufficient data to determine safety		BRONZE POWDER
Safety assessment was based on related chemical		PROPYLENE GLYCOL
Missing safety data noted by cosmetic industry review		ISOSTEARIC ACID
Considered safe based on assumption of low absorption		ACRYLATES COPOLYMER, ACACIA SENEGAL GUM
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		ACACIA SENEGAL GUM, STEARIC ACID, UREA, PVP, PROPYLPARABEN, PHENOXYETHANOL, PANTHENOL, ISOSTEARIC ACID, METHYLPARABEN, GLYCERYL MONOSTEARATE, HYDROXYETHYLCELLULOSE, ETHYLPARABEN, DISODIUM EDTA, COPERNICIA CERIFERA (CARNAUBA) WAX, BHT
Not assessed for safety in cosmetics by industry panel		TITANIUM DIOXIDE (NON-NANO)
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		BUTYLPARABEN
Not assessed for safety in cosmetics by industry panel		SIMETHICONE, VP/ EICOSENE COPOLYMER, POLYISOBUTENE, PANTETHINE, DIMETHICONE PEG-8 POLYACRYLATE, CHROMIUM OXIDE GREENS, CHROMIUM HYDROXIDE GREEN, ALUMINUM POWDER, ACRYLATES/ OCTYLACRYLAMIDE COPOLYMER

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to low doses		PHENOXYETHANOL
Allowed workplace exposures restricted to low doses		CHROMIUM OXIDE GREENS, FERRIC FERROCYANIDE, MICA
Allowed workplace exposures restricted to moderate doses		ALUMINUM POWDER
Allowed workplace exposures restricted to low doses		BHT
Allowed workplace exposures restricted to very low doses		BRONZE POWDER
Allowed workplace exposures restricted to low doses		TITANIUM DIOXIDE (NON-NANO), BENZYL ALCOHOL

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Cancer - limited evidence - immune system		BRONZE POWDER
Interferes with gene expresion		METHYLPARABEN, BUTYLPARABEN
One or more animal studies show blood sugar changes at high doses where the human health implications are not yet well understood		PROPYLENE GLYCOL
One or more animal studies show biochemical changes at low doses where the human health implications are not yet well understood		BHT
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood		TITANIUM DIOXIDE (NON-NANO), SILICA