CALVIN KLEIN ESCAPE MEN EAU DE TOILETTE (2007 formulation) || Skin Deep: Cosmetic Safety Reviews

CALVIN KLEIN ESCAPE MEN EAU DE TOILETTE (2007 FORMULATION)

last updated: 12/01/07 brand: Calvin Klein by Coty, Inc.

SCORE

high hazard (out of 10)

71%

data gap

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97% of body sprays have lower concerns
99% of fragrance for mens have lower concerns

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company's animal testing policy is unknown.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes

Ingredients from packaging: ALCOHOL DENAT., ACRYLATES/OCTYLACRYLAMIDE COPOLYMER, FDC RED #4, DC YELLOW #10, HYDROLYZED JOJOBA ESTERS, FDC BLUE #1, WATER, FRAGRANCE, ETHYLHEXYL METHOXYCINNAMATE, BENZOPHENONE-3, ETHYLHEXYL SALICYLATE, BUTYL METHOXYDIBENZOYLMETHANE, PROPYLENE GLYCOL, BHT

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ingredients

	score	data gap	concerns
OXYBENZONE (BENZOPHENONE-3) (Active Ingredient)	9	55%	Developmental/reproductive toxicity, Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Enhanced skin absorption, Biochemical or cellular level changes
FRAGRANCE	8	100%	Neurotoxicity, Allergies/immunotoxicity, Miscellaneous
OCTINOXATE (OCTYL METHOXYCINNAMATE) ETHYLHEXYL METHOXYCINNAMATE (Active Ingredient)	6	65%	Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Enhanced skin absorption, Biochemical or cellular level changes
BHT	6	61%	Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards, Biochemical or cellular level changes
ALCOHOL DENATURED	5	71%	Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards
PONCEAU SX FDC RED #4	4	73%	Violations, restrictions & warnings
OCTISALATE ETHYLHEXYL SALICYLATE (Active Ingredient)	3	68%	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Enhanced skin absorption
PROPYLENE GLYCOL	4	60%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
FD&C BLUE 1	1	83%	none identified
AVOBENZONE (PARSOL 1789 \| BUTYL METHOXYDIBENZOYLMETHANE) (Active Ingredient)	2	73%	Violations, restrictions & warnings, Contamination concerns (BENZOIC ACID, 4-T-BUTYLBENZOIC ACID, BENZALDEHYDE, P-ANISIC ACID, ACETOPHENONE, DIBENZOYLMETHANE)
KI203 DC YELLOW #10	1	89%	none identified
ACRYLATES/ OCTYLACRYLAMIDE COPOLYMER	0	100%	none identified
HYDROLYZED JOJOBA ESTERS	0	100%	none identified
WATER	0	0%	innocuous

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more in vitro tests non-mammalian cells show positive mutation results		OXYBENZONE (BENZOPHENONE-3)
One or more in vitro tests on mammalian cells show positive mutation results		PROPYLENE GLYCOL,
One or more in vitro tests on mammalian cells show positive mutation results		AVOBENZONE (PARSOL 1789 \| BUTYL METHOXYDIBENZOYLMETHANE)
Cancer - limited evidence		ALCOHOL DENATURED
Cancer - not classifiable/not likely to be human carcinogen		PONCEAU SX, FD&C BLUE 1, BHT

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive effects at high doses		BHT
One or more animal studies show reproductive effects at moderate doses		PROPYLENE GLYCOL,
One or more animal studies show reproductive effects at moderate doses		OCTINOXATE (OCTYL METHOXYCINNAMATE)
Limited evidence of reproductive toxicity		ALCOHOL DENATURED, OXYBENZONE (BENZOPHENONE-3)

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		PROPYLENE GLYCOL
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit)		OXYBENZONE (BENZOPHENONE-3), OCTISALATE, AVOBENZONE (PARSOL 1789 \| BUTYL METHOXYDIBENZOYLMETHANE)
Violation of government restrictions - Banned or found unsafe for use in cosmetics		PONCEAU SX

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show brain and nervous system effects at high doses		PROPYLENE GLYCOL, OXYBENZONE (BENZOPHENONE-3), FD&C BLUE 1
One or more animal studies show brain and nervous system effects at low doses		BHT
Moderate evidence of human neurotoxicity		FRAGRANCE

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show endocrine system disruption at high doses		BHT, ALCOHOL DENATURED
Human any disruptor - strong evidence		OCTINOXATE (OCTYL METHOXYCINNAMATE)
Human any disruptor - moderate evidence		OXYBENZONE (BENZOPHENONE-3)

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Associated with immunotoxicity		AVOBENZONE (PARSOL 1789 \| BUTYL METHOXYDIBENZOYLMETHANE)
One or more human case studies show possible immune effects		OCTISALATE, OCTINOXATE (OCTYL METHOXYCINNAMATE)
Limited evidence of skin and immune system toxicity		PROPYLENE GLYCOL
Possible human photoallergenic toxicant		OXYBENZONE (BENZOPHENONE-3)
Known human immune system toxicant		FRAGRANCE, BHT

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not suspected to be bioaccumulative		ALCOHOL DENATURED
Ingredient is suspected or measured to accumulate in people		OXYBENZONE (BENZOPHENONE-3), OCTINOXATE (OCTYL METHOXYCINNAMATE)

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient)		OCTINOXATE (OCTYL METHOXYCINNAMATE)
One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient)		KI203
One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient)		FD&C BLUE 1, OXYBENZONE (BENZOPHENONE-3)
Limited evidence of respiratory toxicity	products that may be aerosolized (airborne)	PROPYLENE GLYCOL
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		OCTISALATE
Limited evidence of sense organ toxicity		ALCOHOL DENATURED
One or more animal studies show respiratory effects at low doses	products that may be aerosolized (airborne)	BHT

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Occupational hazards related to handling		ALCOHOL DENATURED
Ingredient not fully labeled - identity unknown		FRAGRANCE

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Designated as safe for general or specific, limited use in food		PROPYLENE GLYCOL, FD&C BLUE 1, BHT, ALCOHOL DENATURED
Used in food or as an additive with limited or no toxicity information available		ALCOHOL DENATURED

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Wildlife and environmental toxicity		OXYBENZONE (BENZOPHENONE-3)
Not suspected to be an environmental toxin		ALCOHOL DENATURED
Wildlife and environmental toxicity		OCTINOXATE (OCTYL METHOXYCINNAMATE)

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not likely to be a skin irritant in humans		OXYBENZONE (BENZOPHENONE-3)
One or more animal studies show skin irritation at low doses		OCTISALATE, BHT
Classified as skin irritant		PROPYLENE GLYCOL
One or more animal studies show skin irritation at low doses		ALCOHOL DENATURED

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Insufficient data to determine safety		ALCOHOL DENATURED
Safety assessment was based on related chemical		PROPYLENE GLYCOL
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		OXYBENZONE (BENZOPHENONE-3), BHT
Not assessed for safety in cosmetics by industry panel		PONCEAU SX, KI203, OCTISALATE, HYDROLYZED JOJOBA ESTERS, AVOBENZONE (PARSOL 1789 \| BUTYL METHOXYDIBENZOYLMETHANE), FRAGRANCE, ACRYLATES/ OCTYLACRYLAMIDE COPOLYMER

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to high doses		ALCOHOL DENATURED
Allowed workplace exposures restricted to low doses		BHT

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Does not produces excess reactive oxygen species or other harmful biochemical changes.		OCTISALATE
Produces excess reactive oxygen species that can interfere with cellular signaling, cause mutations, lead to cell death and may be implicated in cardiovascular disease.		OCTINOXATE (OCTYL METHOXYCINNAMATE), OXYBENZONE (BENZOPHENONE-3)
One or more animal studies show blood sugar changes at high doses where the human health implications are not yet well understood		PROPYLENE GLYCOL, ALCOHOL DENATURED
One or more animal studies show biochemical changes at low doses where the human health implications are not yet well understood		BHT