OPI Avojuice Hydrating Body Splash Grapefruit (2007 formulation) || Skin Deep: Cosmetic Safety Reviews

OPI AVOJUICE HYDRATING BODY SPLASH GRAPEFRUIT (2007 FORMULATION)

last updated: 12/01/07 brand: OPI by OPI Products

SCORE

high hazard (out of 10)

76%

data gap

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98% of body sprays have lower concerns
99% of fragrance for womens have lower concerns
99% of moisturizers have lower concerns

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company does not test on animals.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes

Note: This product formulation was confirmed with the FDA VCRD.

Ingredients from packaging: ALCOHOL, PEG-8 DIMETHICONE, LIMONENE, ETHYLHEXYL METHOXYCINNAMATE, ALLANTOIN, PANTHENOL, ALOE BARBADENSIS LEAF EXTRACT, BUTYL METHOXYDIBENZOYLMETHANE, SODIUM HYALURONATE, SILOXANETRIOL ALGINATE, ETHYLHEXYL SALICYLATE, WATER, PEG-40 HYDROGENATED CASTOR OIL, PPG-26-BUTETH-26, GLYCYRRHIZA GLABRA (LICORICE) ROOT EXTRACT, BUTYLENE GLYCOL, MENTHA PIPERITA (PEPPERMINT) LEAF EXTRACT, CAFFEINE, LINALOOL, BUTYLPHENYL METHYLPROPIONAL, BENZYL SALICYLATE, AMYL CINNAMAL, HYDROXYETHYL UREA, HEXYL CINNAMAL, ALPHA-ISOMETHYL IONONE, PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES, RETINYL PALMITATE, TETRAHEXYLDECYL ASCORBATE, TOCOPHERYL ACETATE, DC RED #33, FDC BLUE #1, FRAGRANCE, PROPYLENE GLYCOL, ETHYLHEXYLGLYCERIN, PEG/PPG-8/3 LAURATE, DIMETHICONE PEG-7 COCOATE, ISOPENTYLDIOL

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ingredients

	score	data gap	concerns
FRAGRANCE	8	100%	Neurotoxicity, Allergies/immunotoxicity, Miscellaneous
OCTINOXATE (OCTYL METHOXYCINNAMATE) ETHYLHEXYL METHOXYCINNAMATE (Active Ingredient)	6	65%	Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Enhanced skin absorption, Biochemical or cellular level changes
DIMETHICONE PEG-7 COCOATE	4	76%	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
PEG/ PPG 8/ 3 LAURATE	4	76%	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
PEG-40 HYDROGENATED CASTOR OIL	4	75%	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
PEG-8 DIMETHICONE	4	74%	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
LILIAL BUTYLPHENYL METHYLPROPIONAL	6	64%	Violations, restrictions & warnings, Allergies/immunotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
BENZYL SALICYLATE	6	62%	Violations, restrictions & warnings, Allergies/immunotoxicity
AMYLCINNAMALDEHYDE	6	61%	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
LIMONENE	6	56%	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
ETHANOL ALCOHOL	5	74%	Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards
RETINYL PALMITATE	5	68%	Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
LINALOOL	5	65%	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
TOCOPHERYL ACETATE	4	81%	Allergies/immunotoxicity, Contamination concerns (HYDROQUINONE)
CAFFEINE	4	75%	Developmental/reproductive toxicity, Neurotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
D&C RED 33	1	75%	none identified
ALPHA-ISOMETHYL IONONE	4	68%	Violations, restrictions & warnings, Allergies/immunotoxicity
OCTISALATE ETHYLHEXYL SALICYLATE (Active Ingredient)	3	68%	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Enhanced skin absorption
HEXYL CINNAMAL	4	65%	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
PROPYLENE GLYCOL	4	60%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
PANTHENOL	2	88%	Multiple, additive exposure sources
PPG-26-BUTETH-26	2	88%	Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Contamination concerns (BUTYL ALCOHOL)
FD&C BLUE 1	1	83%	none identified
AVOBENZONE (PARSOL 1789 \| BUTYL METHOXYDIBENZOYLMETHANE) (Active Ingredient)	2	73%	Violations, restrictions & warnings, Contamination concerns (BENZOIC ACID, 4-T-BUTYLBENZOIC ACID, BENZALDEHYDE, P-ANISIC ACID, ACETOPHENONE, DIBENZOYLMETHANE)
ETHYLHEXYLGLYCERIN	1	90%	Irritation (skin, eyes, or lungs)
GLYCYRRHIZA URALENSIS (LICORICE) ROOT EXTRACT GLYCYRRHIZA GLABRA (LICORICE) ROOT EXTRACT	1	85%	none identified
SODIUM HYALURONATE	1	83%	none identified
BUTYLENE GLYCOL	1	79%	Irritation (skin, eyes, or lungs)
ALOE BARBADENSIS (ALOE VERA) LEAF EXTRACT ALOE BARBADENSIS LEAF EXTRACT	1	75%	none identified
MENTHA PIPERITA (PEPPERMINT) LEAF EXTRACT	1	75%	Enhanced skin absorption
HYDROXYETHYL UREA	0	100%	none identified
ISOPENTYLDIOL	0	100%	none identified
SILOXANETRIOL ALGINATE	0	100%	none identified
TETRAHEXYLDECYL ASCORBATE	0	100%	none identified
ALLANTOIN	0	94%	none identified
PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES	0	94%	none identified
WATER	0	0%	innocuous

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more in vitro tests non-mammalian cells show positive mutation results		GLYCYRRHIZA URALENSIS (LICORICE) ROOT EXTRACT, LINALOOL
Cancer - limited evidence		ETHANOL, RETINYL PALMITATE
One or more in vitro tests on mammalian cells show positive mutation results		AVOBENZONE (PARSOL 1789 \| BUTYL METHOXYDIBENZOYLMETHANE)
One or more in vitro tests on mammalian cells show positive mutation results		PROPYLENE GLYCOL, TOCOPHERYL ACETATE
One or more in vitro tests non-mammalian cells show positive mutation results		D&C RED 33
Cancer - not classifiable/not likely to be human carcinogen		FD&C BLUE 1, LIMONENE, CAFFEINE

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Limited evidence of reproductive toxicity		ETHANOL
One or more animal studies show reproductive effects at low doses		CAFFEINE, RETINYL PALMITATE
One or more animal studies show reproductive effects at moderate doses		PROPYLENE GLYCOL, SODIUM HYALURONATE,
One or more animal studies show reproductive effects at moderate doses		OCTINOXATE (OCTYL METHOXYCINNAMATE)
One or more animal studies show developmental effects at high doses		LIMONENE
One or more animal studies show reproductive effects at high doses		BUTYLENE GLYCOL, LILIAL

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		PROPYLENE GLYCOL
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in cosmetics (concentration limit)		AVOBENZONE (PARSOL 1789 \| BUTYL METHOXYDIBENZOYLMETHANE), OCTISALATE, RETINYL PALMITATE
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Fragrance subject to restrictions: safe only if satisfies manufacturing specifications or purity limits, according to industry safety panel (International Fragrance Association)		LIMONENE, LINALOOL, ALPHA-ISOMETHYL IONONE, AMYLCINNAMALDEHYDE, BENZYL SALICYLATE
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		PEG/ PPG 8/ 3 LAURATE, PEG-8 DIMETHICONE, PEG-40 HYDROGENATED CASTOR OIL, MENTHA PIPERITA (PEPPERMINT) LEAF EXTRACT, DIMETHICONE PEG-7 COCOATE, ALOE BARBADENSIS (ALOE VERA) LEAF EXTRACT, D&C RED 33
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Fragrance subject to restrictions: safe only within recommended use or concentration limitsn)		HEXYL CINNAMAL, LILIAL

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show brain and nervous system effects at moderate doses		LINALOOL, SODIUM HYALURONATE, GLYCYRRHIZA URALENSIS (LICORICE) ROOT EXTRACT
One or more animal studies show brain and nervous system effects at high doses		AMYLCINNAMALDEHYDE, BUTYLENE GLYCOL, FD&C BLUE 1, PROPYLENE GLYCOL, RETINYL PALMITATE
nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study		ETHANOL
One or more animal studies show brain and nervous system effects at high doses		HEXYL CINNAMAL
Moderate evidence of human neurotoxicity		FRAGRANCE
One or more animal studies show brain and nervous system effects at very low doses		CAFFEINE
One or more animal studies show brain and nervous system effects at moderate doses		LILIAL

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Associated with endocrine disruption		LILIAL
One or more animal studies show endocrine system disruption at high doses		CAFFEINE
Associated with endocrine disruption		BENZYL SALICYLATE
One or more animal studies show endocrine disruption at moderate doses		GLYCYRRHIZA URALENSIS (LICORICE) ROOT EXTRACT
One or more animal studies show endocrine system disruption at high doses		BUTYLENE GLYCOL
Human any disruptor - strong evidence		OCTINOXATE (OCTYL METHOXYCINNAMATE)

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Possible human immune system toxicant		HEXYL CINNAMAL, LINALOOL
Human skin toxicant - strong evidence		TOCOPHERYL ACETATE
Limited evidence of skin and immune system toxicity		PROPYLENE GLYCOL
One or more human case studies show possible immune effects		OCTISALATE, OCTINOXATE (OCTYL METHOXYCINNAMATE)
Associated with immunotoxicity		AVOBENZONE (PARSOL 1789 \| BUTYL METHOXYDIBENZOYLMETHANE)
Possible human immune system toxicant		ALPHA-ISOMETHYL IONONE, LILIAL
Known human immune system toxicant		FRAGRANCE, BENZYL SALICYLATE, LIMONENE, AMYLCINNAMALDEHYDE

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Persistent, bioaccumulative in wildlife		CAFFEINE
Ingredient is suspected or measured to accumulate in people		OCTINOXATE (OCTYL METHOXYCINNAMATE)
Not suspected to be bioaccumulative		ETHANOL

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient)		OCTINOXATE (OCTYL METHOXYCINNAMATE)
One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient)		PPG-26-BUTETH-26, PANTHENOL, LINALOOL, HEXYL CINNAMAL, LIMONENE, BUTYLENE GLYCOL, BENZYL SALICYLATE
One or more animal studies show respiratory effects at moderate doses (low dose studies may be unavailable for this ingredient)	products that may be aerosolized (airborne)	LILIAL
One or more animal studies show gastrointestinal effects at moderate doses (low dose studies may be unavailable for this ingredient)		GLYCYRRHIZA URALENSIS (LICORICE) ROOT EXTRACT,
One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient)		FD&C BLUE 1
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		TOCOPHERYL ACETATE, OCTISALATE, SODIUM HYALURONATE
Limited evidence of skin toxicity		RETINYL PALMITATE, PEG/ PPG 8/ 3 LAURATE, PEG-8 DIMETHICONE, PEG-40 HYDROGENATED CASTOR OIL, DIMETHICONE PEG-7 COCOATE, ETHANOL
Limited evidence of respiratory toxicity	products that may be aerosolized (airborne)	PROPYLENE GLYCOL
One or more animal studies show cardiovascular effects at very low doses		CAFFEINE

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Occupational hazards related to handling		LIMONENE, ETHANOL
Ingredient not fully labeled - identity unknown		FRAGRANCE

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Designated as safe for general or specific, limited use in food		GLYCYRRHIZA URALENSIS (LICORICE) ROOT EXTRACT, TOCOPHERYL ACETATE, RETINYL PALMITATE, PEG/ PPG 8/ 3 LAURATE, PROPYLENE GLYCOL, PEG-8 DIMETHICONE, PEG-40 HYDROGENATED CASTOR OIL, LINALOOL, HEXYL CINNAMAL, FD&C BLUE 1, ETHANOL, LIMONENE, DIMETHICONE PEG-7 COCOATE, CAFFEINE, BUTYLENE GLYCOL, BENZYL SALICYLATE, AMYLCINNAMALDEHYDE, ALPHA-ISOMETHYL IONONE
Used in food or as an additive with limited or no toxicity information available		PPG-26-BUTETH-26, PANTHENOL, ETHANOL

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not suspected to be an environmental toxin		ETHANOL
Wildlife and environmental toxicity		OCTINOXATE (OCTYL METHOXYCINNAMATE)
Wildlife and environmental toxicity		LIMONENE

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show skin irritation at moderate doses		SODIUM HYALURONATE, PPG-26-BUTETH-26, CAFFEINE
One or more animal studies show skin irritation at low doses		OCTISALATE, ETHANOL
One or more animal studies show skin irritation at very low doses		LINALOOL
One or more animal studies show skin irritation at low doses		LILIAL
One or more animal studies show skin irritation at very low doses		HEXYL CINNAMAL, AMYLCINNAMALDEHYDE
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	BUTYLENE GLYCOL
Classified as skin irritant		PROPYLENE GLYCOL, ETHYLHEXYLGLYCERIN, LIMONENE

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Safety assessment was based on related chemical		PROPYLENE GLYCOL
Missing safety data noted by cosmetic industry review		ALOE BARBADENSIS (ALOE VERA) LEAF EXTRACT
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		TOCOPHERYL ACETATE, RETINYL PALMITATE, PPG-26-BUTETH-26, PEG-8 DIMETHICONE, PANTHENOL, BUTYLENE GLYCOL
Not assessed for safety in cosmetics by industry panel		PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES, GLYCYRRHIZA URALENSIS (LICORICE) ROOT EXTRACT, TETRAHEXYLDECYL ASCORBATE, SILOXANETRIOL ALGINATE, PEG/ PPG 8/ 3 LAURATE, OCTISALATE, LINALOOL, ISOPENTYLDIOL, HYDROXYETHYL UREA, HEXYL CINNAMAL, FRAGRANCE, ETHYLHEXYLGLYCERIN, ETHANOL, LIMONENE, DIMETHICONE PEG-7 COCOATE, CAFFEINE, LILIAL, BENZYL SALICYLATE, AVOBENZONE (PARSOL 1789 \| BUTYL METHOXYDIBENZOYLMETHANE), AMYLCINNAMALDEHYDE, ALPHA-ISOMETHYL IONONE, ALLANTOIN

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to high doses		ETHANOL

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Does not produces excess reactive oxygen species or other harmful biochemical changes.		OCTISALATE
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood		CAFFEINE
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		ETHANOL, PROPYLENE GLYCOL
Produces excess reactive oxygen species that can interfere with cellular signaling, cause mutations, lead to cell death and may be implicated in cardiovascular disease.		RETINYL PALMITATE, OCTINOXATE (OCTYL METHOXYCINNAMATE)