BUMBLE AND BUMBLE DEHYDRATION THERAPY COMPLEX (2007 formulation) || Skin Deep: Cosmetic Safety Reviews

BUMBLE AND BUMBLE DEHYDRATION THERAPY COMPLEX (2007 FORMULATION)

last updated: 12/01/07 brand: Bumble and Bumble by Estée Lauder

SCORE

high hazard (out of 10)

84%

data gap

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100% of conditioners have lower concerns

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company does not test on animals.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes

Ingredients from packaging: WATER, HYDROLYZED WHEAT PROTEIN, HYDROGENATED LECITHIN, SIMMONDSIA CHINENSIS (JOJOBA) SEED OIL, PANTETHINE, POLYGONUM CUSPIDATUM ROOT EXTRACT, TETRAHEXYLDECYL ASCORBATE, ROSMARINUS OFFICINALIS (ROSEMARY) LEAF EXTRACT, GLYCERIN, CREATINE, CAFFEINE, CYCLOPENTASILOXANE, SACCHAROMYCES LYSATE EXTRACT, ACETYL GLUCOSAMINE, SODIUM MANNOSE PHOSPHATE, DIMETHICONOL, AMODIMETHICONE, CETEARYL ALCOHOL, SODIUM STEAROYL GLUTAMATE, ISOSTEARAMIDOPROPYL DIMETHYLAMINE, CETRIMONIUM METHOSULFATE, PEG-7M, CETYL ALCOHOL, C12-20 ALKYL GLUCOSIDE, C14-22 ALCOHOLS, C11-15 PARETH-7, C12-16 PARETH-9, PPG-1 TRIDECETH-6, METHYL GLUCETH-10, OLETH-10, OLETH-20, GLYCERYL STEARATE, PEG-100 STEARATE, CERAMIDE 3, TRIDECETH-12, POLYQUATERNIUM-11, POLYQUATERNIUM-37, QUATERNIUM-91, PROPYLENE GLYCOL DICAPRYLATE/DICAPRATE, ALCOHOL DENAT., HYDROXYETHYLCELLULOSE, ETHYLHEXYL METHOXYCINNAMATE, CITRIC ACID, BHT, LINOLEIC ACID, DISODIUM EDTA, PHENOXYETHANOL, METHYLPARABEN, BUTYLPARABEN, ISOBUTYLPARABEN, GERANIOL, HYDROXYISOHEXYL 3-CYCLOHEXENE CARBOXALDEHYDE, LIMONENE, BUTYLPHENYL METHYLPROPIONAL, CITRONELLOL, CHOLESTEROL, LINALOOL, FRAGRANCE, PHYTANTRIOL, PANTHENYL ETHYL ETHER, PANTHENOL

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ingredients

	score	data gap	concerns
METHYLPARABEN	10	63%	Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes
FRAGRANCE	8	100%	Neurotoxicity, Allergies/immunotoxicity, Miscellaneous
OCTINOXATE (OCTYL METHOXYCINNAMATE) ETHYLHEXYL METHOXYCINNAMATE (Active Ingredient)	6	65%	Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Enhanced skin absorption, Biochemical or cellular level changes
PEG-100 STEARATE	4	69%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
BUTYLPARABEN	6	79%	Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
PEG-7M	4	76%	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
LILIAL BUTYLPHENYL METHYLPROPIONAL	5	64%	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
LYRAL HYDROXYISOHEXYL 3-CYCLOHEXENE CARBOXALDEHYDE	5	62%	Violations, restrictions & warnings, Allergies/immunotoxicity
BHT	6	61%	Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards, Biochemical or cellular level changes
GERANIOL	6	61%	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
LIMONENE	6	56%	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
ALCOHOL DENATURED	5	71%	Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards
CITRONELLOL	4	65%	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
LINALOOL	5	65%	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
OLETH-10	3	87%	Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
OLETH-20	3	87%	Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
CAFFEINE	4	75%	Developmental/reproductive toxicity, Neurotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
PHENOXYETHANOL	4	67%	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Occupational hazards
PHYTANTRIOL	3	88%	Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
ISOBUTYLPARABEN	3	83%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
CYCLOPENTASILOXANE	2	79%	Persistence and bioaccumulation
DISODIUM EDTA	3	78%	Neurotoxicity, Organ system toxicity (non-reproductive), Enhanced skin absorption
CITRIC ACID	2	72%	Violations, restrictions & warnings
PANTHENOL	2	88%	Multiple, additive exposure sources
CHOLESTEROL	2	74%	Persistence and bioaccumulation
GLYCERIN	2	74%	Organ system toxicity (non-reproductive), Occupational hazards
HYDROGENATED LECITHIN	2	74%	Enhanced skin absorption, Contamination concerns (NITROSAMINES)
HYDROLYZED WHEAT PROTEIN	1	95%	Allergies/immunotoxicity
ISOSTEARAMIDOPROPYL DIMETHYLAMINE	0	94%	none identified
POLYQUATERNIUM-37	0	94%	none identified
CETRIMONIUM METHOSULFATE	0	94%	none identified
CETEARYL ALCOHOL	0	93%	none identified
LINOLEIC ACID	1	93%	Irritation (skin, eyes, or lungs)
PROPYLENE GLYCOL DICAPRYLATE/DICAPRATE	0	90%	Enhanced skin absorption
ACETYL GLUCOSAMINE	1	89%	none identified
C11-15 PARETH-7	1	88%	none identified
GLYCERYL MONOSTEARATE GLYCERYL STEARATE	1	88%	none identified
SIMMONDSIA CHINENSIS (JOJOBA) SEED WAX SIMMONDSIA CHINENSIS (JOJOBA) SEED OIL	1	88%	none identified
TRIDECETH-12	1	88%	Organ system toxicity (non-reproductive)
CETYL ALCOHOL	1	87%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
PANTETHINE	1	87%	none identified
HYDROXYETHYLCELLULOSE	1	82%	none identified
C12-16 PARETH-9	0	100%	none identified
CERAMIDE 3	0	100%	none identified
DIMETHICONOL	0	100%	none identified
PANTHENYL ETHYL ETHER	0	100%	none identified
POLYGONUM CUSPIDATUM (JAPANESE KNOTWEED) ROOT EXTRACT POLYGONUM CUSPIDATUM ROOT EXTRACT	0	100%	none identified
PPG-1 TRIDECETH-6	0	100%	none identified
ROSMARINUS OFFICINALIS (ROSEMARY) LEAF EXTRACT	0	100%	none identified
SODIUM MANNOSE PHOSPHATE	0	100%	none identified
SODIUM STEAROYL GLUTAMATE	0	100%	none identified
TETRAHEXYLDECYL ASCORBATE	0	100%	none identified
C12-20 ALKYL GLUCOSIDE	0	100%	none identified
C14-22 ALCOHOLS	0	100%	none identified
QUATERNIUM-91	0	100%	none identified
AMODIMETHICONE	0	99%	none identified
CREATINE	0	94%	none identified
METHYL GLUCETH-10	0	94%	none identified
POLYQUATERNIUM-11	0	93%	none identified
SACCHAROMYCES LYSATE EXTRACT	0	93%	none identified
WATER	0	0%	innocuous

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more in vitro tests non-mammalian cells show positive mutation results		PHENOXYETHANOL, LINALOOL
One or more animal studies show tumor formation at moderate doses		PEG-100 STEARATE,
One or more animal studies show tumor formation at moderate doses		CYCLOPENTASILOXANE
One or more in vitro tests on mammalian cells show positive mutation results		METHYLPARABEN, GLYCERIN, GERANIOL, DISODIUM EDTA, BUTYLPARABEN
Cancer - limited evidence		ALCOHOL DENATURED
Cancer - not classifiable/not likely to be human carcinogen		LIMONENE, CHOLESTEROL, CAFFEINE, BHT

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive effects at high doses		HYDROXYETHYLCELLULOSE, PEG-100 STEARATE, LILIAL, DISODIUM EDTA, BHT,
One or more animal studies show developmental effects at high doses		LIMONENE
One or more animal studies show reproductive effects at moderate doses		OCTINOXATE (OCTYL METHOXYCINNAMATE)
One or more animal studies show reproductive effects at moderate doses		PANTETHINE, GLYCERIN, CHOLESTEROL
One or more animal studies show reproductive effects at low doses		CAFFEINE
Limited evidence of reproductive toxicity		ALCOHOL DENATURED
One or more animal studies show any effects at very low doses		BUTYLPARABEN

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		PEG-100 STEARATE, PEG-7M, HYDROGENATED LECITHIN
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Fragrance subject to restrictions: safe only within recommended use or concentration limitsn)		LYRAL, GERANIOL, CITRONELLOL, LILIAL, LINALOOL, LIMONENE
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		CITRIC ACID, PHENOXYETHANOL
Violation of government restrictions - Banned or found unsafe for use in cosmetics		METHYLPARABEN

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show brain and nervous system effects at high doses		HYDROXYETHYLCELLULOSE, GLYCERIN, CHOLESTEROL
One or more animal studies show brain and nervous system effects at moderate doses		PHENOXYETHANOL, METHYLPARABEN, LINALOOL, GERANIOL, CITRONELLOL, LILIAL,
One or more animal studies show any effects at moderate doses		CYCLOPENTASILOXANE
One or more animal studies show brain and nervous system effects at low doses		DISODIUM EDTA, BHT
One or more animal studies show brain and nervous system effects at very low doses		CAFFEINE
Moderate evidence of human neurotoxicity		FRAGRANCE

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show endocrine system disruption at high doses		DISODIUM EDTA, GLYCERIN
Associated with endocrine disruption		LILIAL
One or more animal studies show endocrine system disruption at high doses		CAFFEINE, CHOLESTEROL, BHT, ALCOHOL DENATURED
One or more animal studies show endocrine disruption at moderate doses		ISOBUTYLPARABEN,
One or more animal studies show endocrine disruption at moderate doses		CYCLOPENTASILOXANE
Human any disruptor - strong evidence		OCTINOXATE (OCTYL METHOXYCINNAMATE), METHYLPARABEN, BUTYLPARABEN

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Possible human immune system toxicant		LINALOOL
Limited evidence of skin and immune system toxicity		PHENOXYETHANOL
One or more human case studies show possible skin allergy effects		HYDROLYZED WHEAT PROTEIN, OCTINOXATE (OCTYL METHOXYCINNAMATE)
Human skin toxicant - strong evidence		PHYTANTRIOL, METHYLPARABEN, ISOBUTYLPARABEN, BUTYLPARABEN
Possible human immune system toxicant		CITRONELLOL, LILIAL
Known human immune system toxicant		LYRAL, GERANIOL, FRAGRANCE, LIMONENE, BHT

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not suspected to be bioaccumulative		ALCOHOL DENATURED
Not suspected to be persistent		TRIDECETH-12, CETYL ALCOHOL
Persistent, bioaccumulative in wildlife		CHOLESTEROL
Ingredient is suspected or measured to accumulate in people		OCTINOXATE (OCTYL METHOXYCINNAMATE)
Persistent, bioaccumulative in wildlife		CYCLOPENTASILOXANE, CAFFEINE

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient)		OCTINOXATE (OCTYL METHOXYCINNAMATE)
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient)		TRIDECETH-12, CYCLOPENTASILOXANE, ACETYL GLUCOSAMINE, SIMMONDSIA CHINENSIS (JOJOBA) SEED WAX, HYDROXYETHYLCELLULOSE, CETYL ALCOHOL, PANTHENOL, PANTETHINE, LINALOOL, LIMONENE, CITRONELLOL, C11-15 PARETH-7, CHOLESTEROL
One or more animal studies show gastrointestinal effects at moderate doses (low dose studies may be unavailable for this ingredient)		PHENOXYETHANOL, OLETH-20, OLETH-10, LINOLEIC ACID, GLYCERYL MONOSTEARATE, CITRIC ACID
Limited evidence of sense organ toxicity		PEG-100 STEARATE, PEG-7M, ISOBUTYLPARABEN, BUTYLPARABEN, ALCOHOL DENATURED
One or more animal studies show broad systemic effects at low doses		GERANIOL, DISODIUM EDTA, BHT
One or more animal studies show kidney or renal system effects at very low doses		GLYCERIN, CAFFEINE
Known human any toxicant		METHYLPARABEN

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Occupational hazards related to handling		LIMONENE
Ingredient not fully labeled - identity unknown		FRAGRANCE
Occupational hazards related to handling		ALCOHOL DENATURED

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Designated as safe for general or specific, limited use in food		LINOLEIC ACID, METHYLPARABEN, LINALOOL, LIMONENE, PEG-7M, PEG-100 STEARATE, ROSMARINUS OFFICINALIS (ROSEMARY) LEAF EXTRACT, DISODIUM EDTA, GERANIOL, GLYCERIN, GLYCERYL MONOSTEARATE, BHT, BUTYLPARABEN, CAFFEINE, CETYL ALCOHOL, CITRIC ACID, CITRONELLOL
Used in food or as an additive with limited or no toxicity information available		ALCOHOL DENATURED
Designated as safe for general or specific, limited use in food		ALCOHOL DENATURED
Used in food or as an additive with limited or no toxicity information available		PANTHENOL

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Suspected to be an environmental toxin		TRIDECETH-12
Wildlife and environmental toxicity		LIMONENE
Wildlife and environmental toxicity		OCTINOXATE (OCTYL METHOXYCINNAMATE)
Suspected to be an environmental toxin		CETYL ALCOHOL
Not suspected to be an environmental toxin		ALCOHOL DENATURED

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show skin irritation at high doses		CHOLESTEROL
One or more animal studies show skin irritation at moderate doses		TRIDECETH-12, LYRAL, GLYCERIN, CYCLOPENTASILOXANE, CITRIC ACID, CAFFEINE, C11-15 PARETH-7
One or more animal studies show skin irritation at low doses		LILIAL, LINOLEIC ACID, METHYLPARABEN, OLETH-10
One or more animal studies show skin irritation at moderate doses		BUTYLPARABEN
One or more animal studies show skin irritation at very low doses		LINALOOL, PEG-100 STEARATE
One or more animal studies show skin irritation at low doses		ALCOHOL DENATURED
Classified as irritant		LIMONENE, PHENOXYETHANOL
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	PHYTANTRIOL
One or more animal studies show skin irritation at low doses		BHT, OLETH-20
One or more animal studies show skin irritation at very low doses		CETYL ALCOHOL, CITRONELLOL, GERANIOL

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not assessed for safety in cosmetics by industry panel		ACETYL GLUCOSAMINE
Safety assessment was based on related chemical		OLETH-20, PROPYLENE GLYCOL DICAPRYLATE/DICAPRATE, OLETH-10
Missing safety data noted by cosmetic industry review		PHYTANTRIOL
Insufficient data to determine safety		ALCOHOL DENATURED
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		PROPYLENE GLYCOL DICAPRYLATE/DICAPRATE
Safety assessment was based on related chemical		AMODIMETHICONE, ISOBUTYLPARABEN, PEG-100 STEARATE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		PEG-100 STEARATE, BUTYLPARABEN, OLETH-20, POLYQUATERNIUM-11, PHYTANTRIOL, PHENOXYETHANOL, PANTHENOL, OLETH-10, METHYLPARABEN, HYDROXYETHYLCELLULOSE, GLYCERYL MONOSTEARATE, DISODIUM EDTA, CHOLESTEROL, CETYL ALCOHOL, CETEARYL ALCOHOL, BHT
Not assessed for safety in cosmetics by industry panel		TRIDECETH-12
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		AMODIMETHICONE
Not assessed for safety in cosmetics by industry panel		SIMMONDSIA CHINENSIS (JOJOBA) SEED WAX, SACCHAROMYCES LYSATE EXTRACT, QUATERNIUM-91, CETRIMONIUM METHOSULFATE, C14-22 ALCOHOLS, C12-20 ALKYL GLUCOSIDE, SODIUM STEAROYL GLUTAMATE, PPG-1 TRIDECETH-6, TETRAHEXYLDECYL ASCORBATE, SODIUM MANNOSE PHOSPHATE, ROSMARINUS OFFICINALIS (ROSEMARY) LEAF EXTRACT, POLYGONUM CUSPIDATUM (JAPANESE KNOTWEED) ROOT EXTRACT, POLYQUATERNIUM-37, PANTHENYL ETHYL ETHER, PEG-7M, METHYL GLUCETH-10, PANTETHINE, LINOLEIC ACID, LYRAL, ISOSTEARAMIDOPROPYL DIMETHYLAMINE, LINALOOL, HYDROLYZED WHEAT PROTEIN, GLYCERIN, GERANIOL, FRAGRANCE, LIMONENE, DIMETHICONOL, CITRONELLOL, CYCLOPENTASILOXANE, CREATINE, CITRIC ACID, CERAMIDE 3, CAFFEINE, C12-16 PARETH-9, C11-15 PARETH-7, LILIAL

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to low doses		PHENOXYETHANOL
Allowed workplace exposures restricted to low doses		BHT
Allowed workplace exposures restricted to moderate doses		GLYCERIN
Allowed workplace exposures restricted to high doses		ALCOHOL DENATURED

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Produces excess reactive oxygen species that can interfere with cellular signaling, cause mutations, lead to cell death and may be implicated in cardiovascular disease.		OCTINOXATE (OCTYL METHOXYCINNAMATE)
Interferes with gene expresion		BUTYLPARABEN, METHYLPARABEN
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		ALCOHOL DENATURED, SIMMONDSIA CHINENSIS (JOJOBA) SEED WAX, GLYCERIN, CHOLESTEROL, CITRIC ACID, CYCLOPENTASILOXANE
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood		CAFFEINE
One or more animal studies show biochemical changes at low doses where the human health implications are not yet well understood		BHT