Avon ADVANCE TECHNIQUES KEEP CLEAR DANDRUFF 2 IN 1 SHAMPOO (2007 formulation) || Skin Deep: Cosmetic Safety Reviews

AVON ADVANCE TECHNIQUES KEEP CLEAR DANDRUFF 2 IN 1 SHAMPOO (2007 FORMULATION)

last updated: 12/01/07 brand: Avon by Avon Products, Inc.

SCORE

moderate hazard (out of 10)

78%

data gap

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70% of dandruff/scalp treatments have lower concerns
65% of shampoos have lower concerns

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company does not test on animals.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns

Ingredients from packaging: WATER, GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE, SODIUM CHLORIDE, SODIUM LAUROYL SARCOSINATE, ACRYLATES COPOLYMER, FRAGRANCE, POLYGLYCERYL-3 LAURATE, GLYCOL DISTEARATE, SODIUM HYDROXYMETHYLGLYCINATE, DISODIUM EDTA, PEG-12 DIMETHICONE, SODIUM LAURETH SULFATE, QUATERNIUM-80, CITRIC ACID, SODIUM HYDROXIDE, DIMETHYLPABAMIDOPROPYL LAURDIMONIUM TOSYLATE, PROPYLENE GLYCOL STEARATE, DC GREEN #5, DC RED #33, COCAMIDE MEA, SODIUM LAURYL SULFATE, COCAMIDOPROPYL BETAINE, ZINC PYRITHIONE, CREATINE, LAMINARIA DIGITATA EXTRACT, PELVETIA CANALICULATA EXTRACT

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ingredients

	score	data gap	concerns
FRAGRANCE	8	100%	Neurotoxicity, Allergies/immunotoxicity, Miscellaneous
PEG-12 DIMETHICONE	6	75%	Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
ZINC PYRITHIONE	5	66%	Violations, restrictions & warnings, Allergies/immunotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive)
COCAMIDOPROPYL BETAINE	5	63%	Allergies/immunotoxicity, Contamination concerns (NITROSAMINES)
SODIUM LAURETH-5 SULFATE SODIUM LAURETH SULFATE	4	88%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
COCAMIDE MEA	2	75%	Contamination concerns (NITROSAMINES)
D&C RED 33	1	75%	none identified
SODIUM LAUROYL SARCOSINATE	4	73%	Violations, restrictions & warnings, Enhanced skin absorption, Contamination concerns (NITROSAMINES)
DISODIUM EDTA	3	78%	Neurotoxicity, Organ system toxicity (non-reproductive), Enhanced skin absorption
SODIUM HYDROXIDE	3	77%	Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
ACRYLATES COPOLYMER	3	75%	Contamination concerns (METHACRYLIC ACID, ACRYLIC ACID, 2-ETHYLHEXYL ACRYLATE)
CITRIC ACID	2	72%	Violations, restrictions & warnings
SODIUM LAURYL SULFATE	3	68%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
SODIUM HYDROXYMETHYLGLYCINATE	2	100%	Contamination concerns (FORMALDEHYDE)
DIMETHYLPABAMIDOPROPYL LAURDIMONIUM TOSYLATE	2	83%	Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
GLYCOL DISTEARATE	1	93%	Multiple, additive exposure sources
PROPYLENE GLYCOL STEARATE	1	88%	none identified
GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE	1	87%	none identified
MIDORI201 DC GREEN #5	1	87%	none identified
LAMINARIA DIGITATA (HORSETAIL KELP) EXTRACT LAMINARIA DIGITATA EXTRACT	0	100%	none identified
PELVETIA CANALICULATA (CHANNELLED WRACK) EXTRACT PELVETIA CANALICULATA EXTRACT	0	100%	none identified
POLYGLYCERYL-3 LAURATE	0	100%	none identified
QUATERNIUM-80	0	100%	none identified
CREATINE	0	94%	none identified
SODIUM CHLORIDE	0	0%	innocuous
WATER	0	0%	innocuous

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more in vitro tests non-mammalian cells show positive mutation results		D&C RED 33
One or more in vitro tests on mammalian cells show positive mutation results		SODIUM LAURYL SULFATE, SODIUM HYDROXIDE, SODIUM CHLORIDE, DISODIUM EDTA

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive effects at high doses		SODIUM LAURYL SULFATE
One or more animal studies show reproductive effects at moderate doses		ZINC PYRITHIONE
One or more animal studies show reproductive effects at high doses		DISODIUM EDTA

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		SODIUM LAURYL SULFATE, SODIUM LAUROYL SARCOSINATE, COCAMIDOPROPYL BETAINE, PEG-12 DIMETHICONE, ACRYLATES COPOLYMER, COCAMIDE MEA, D&C RED 33
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit)		ZINC PYRITHIONE, CITRIC ACID, SODIUM LAUROYL SARCOSINATE, SODIUM LAUROYL SARCOSINATE
Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Not safe for use on injured or damaged skin	products for use on damaged skin	PEG-12 DIMETHICONE

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show brain and nervous system effects at moderate doses		ZINC PYRITHIONE
One or more animal studies show brain and nervous system effects at high doses		GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE
One or more animal studies show brain and nervous system effects at very low doses		SODIUM HYDROXIDE
One or more animal studies show brain and nervous system effects at low doses		DISODIUM EDTA
One or more animal studies show brain and nervous system effects at moderate doses		SODIUM LAURYL SULFATE
Moderate evidence of human neurotoxicity		FRAGRANCE

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show endocrine system disruption at high doses		SODIUM LAURYL SULFATE, DISODIUM EDTA

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Limited evidence of immune system toxicity	products for use on skin	DIMETHYLPABAMIDOPROPYL LAURDIMONIUM TOSYLATE
Known human immune system toxicant		FRAGRANCE
Limited evidence of immune system toxicity		ZINC PYRITHIONE
Known human immune system toxicant		COCAMIDOPROPYL BETAINE

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not suspected to be bioaccumulative		SODIUM HYDROXIDE
Not suspected to be persistent		SODIUM LAURYL SULFATE
Persistent, bioaccumulative in wildlife		ZINC PYRITHIONE

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient)		MIDORI201
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		SODIUM LAURETH-5 SULFATE, PROPYLENE GLYCOL STEARATE, CITRIC ACID
Limited evidence of sense organ toxicity		PEG-12 DIMETHICONE
One or more animal studies show metabolic effects at very low doses		SODIUM HYDROXIDE
One or more animal studies show broad systemic effects at low doses		DISODIUM EDTA, SODIUM LAURYL SULFATE, ZINC PYRITHIONE

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Occupational hazards related to handling		SODIUM HYDROXIDE
Ingredient not fully labeled - identity unknown		FRAGRANCE

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Designated as safe for general or specific, limited use in food		SODIUM LAURYL SULFATE, SODIUM HYDROXIDE, SODIUM CHLORIDE, PROPYLENE GLYCOL STEARATE, PEG-12 DIMETHICONE, DISODIUM EDTA, CITRIC ACID
Used in food or as an additive with limited or no toxicity information available		GLYCOL DISTEARATE

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Suspected to be an environmental toxin		ZINC PYRITHIONE, SODIUM LAURYL SULFATE
Not suspected to be an environmental toxin		SODIUM HYDROXIDE
Wildlife and environmental toxicity		DIMETHYLPABAMIDOPROPYL LAURDIMONIUM TOSYLATE

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show skin irritation at moderate doses		MIDORI201, SODIUM CHLORIDE, CITRIC ACID
One or more animal studies show skin irritation at very low doses		SODIUM HYDROXIDE
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	SODIUM LAURETH-5 SULFATE, SODIUM LAURYL SULFATE
Classified as irritant		DIMETHYLPABAMIDOPROPYL LAURDIMONIUM TOSYLATE

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Considered safe based on assumption of low absorption		ACRYLATES COPOLYMER
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		SODIUM LAURETH-5 SULFATE, PROPYLENE GLYCOL STEARATE, GLYCOL DISTEARATE, PEG-12 DIMETHICONE, DISODIUM EDTA
Not assessed for safety in cosmetics by industry panel		MIDORI201, ZINC PYRITHIONE, SODIUM HYDROXYMETHYLGLYCINATE, SODIUM HYDROXIDE, QUATERNIUM-80, POLYGLYCERYL-3 LAURATE, PELVETIA CANALICULATA (CHANNELLED WRACK) EXTRACT, LAMINARIA DIGITATA (HORSETAIL KELP) EXTRACT, GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE, FRAGRANCE, DIMETHYLPABAMIDOPROPYL LAURDIMONIUM TOSYLATE, CREATINE, CITRIC ACID

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
No workplace limits set		SODIUM HYDROXIDE

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood		SODIUM LAURYL SULFATE
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		CITRIC ACID, MIDORI201