

Compact for Safe Cosmetics
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Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: Neurotoxicity, Organ system toxicity (non-reproductive), Miscellaneous, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards |
Ingredients from packaging: Water, Coco Glucoside, Aminomethyl Propanol, Isopropyl Alcohol, Carbomer, Isopropyl Acetate, Fragrance, 2-Methyl-Hydroxyethylaminophenol, 1,2,4-Trihydroxybenzene, p-Phenylenediamine, Trisodium EDTA, Erythorbic Acid, Sodium Sulfite, p-Aminophenol, Sulfuric Acid, N,N-Bis(2-Hydroxyethyl-p-Phenylenediamine Sulfate, Cinnamidopropyl Trimethyl Ammonium Chloride
| score | data gap | concerns | |
| P-PHENYLENEDIAMINE | 10 | 52% | Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| P-AMINOPHENOL | 8 | 57% | Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards |
| FRAGRANCE | 8 | 100% | Neurotoxicity, Allergies/immunotoxicity, Miscellaneous |
| SULFURIC ACID | 5 | 65% | Cancer, Organ system toxicity (non-reproductive), Occupational hazards |
| ISOPROPYL ALCOHOL | 4 | 72% | Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| SODIUM SULFITE | 3 | 87% | Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive) |
| 2-METHYL-5-HYDROXYETHYLAMINOPHENOL 2-METHYL-HYDROXYETHYLAMINOPHENOL | 3 | 73% | Cancer, Allergies/immunotoxicity |
| 1,2,4-TRIHYDROXYBENZENE | 3 | 73% | Cancer, Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE | 3 | 69% | Cancer, Allergies/immunotoxicity |
| AMINOMETHYL PROPANOL | 2 | 71% | Irritation (skin, eyes, or lungs), Contamination concerns (NITROSAMINES, OXAZOLIDINE) |
| ERYTHORBIC ACID | 1 | 87% | none identified |
| TRISODIUM EDTA | 1 | 86% | Enhanced skin absorption |
| ISOPROPYL ACETATE | 1 | 79% | Irritation (skin, eyes, or lungs), Occupational hazards |
| CINNAMIDOPROPYLTRIMONIUM CHLORIDE CINNAMIDOPROPYL TRIMETHYL AMMONIUM CHLORIDE | 0 | 100% | none identified |
| COCO-GLUCOSIDE | 0 | 100% | none identified |
| CARBOMER | 0 | 93% | none identified |
| WATER | 0 | 0% | innocuous |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more in vitro tests on mammalian cells show positive mutation results | SODIUM SULFITE, ERYTHORBIC ACID | |
| Cancer - limited evidence | 1,2,4-TRIHYDROXYBENZENE, N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE, 2-METHYL-5-HYDROXYETHYLAMINOPHENOL | |
| Mutagen - limited evidence | P-AMINOPHENOL | |
| Cancer - not classifiable/not likely to be human carcinogen | P-PHENYLENEDIAMINE, ISOPROPYL ALCOHOL | |
| Known human carcinogen | SULFURIC ACID |
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show reproductive effects at moderate doses | P-AMINOPHENOL | |
| Limited evidence of developmental toxicity | ISOPROPYL ALCOHOL | |
| Human nervous system toxicant - moderate evidence | P-PHENYLENEDIAMINE |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | AMINOMETHYL PROPANOL, 1,2,4-TRIHYDROXYBENZENE, P-PHENYLENEDIAMINE, P-AMINOPHENOL, N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE | |
| Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel | P-AMINOPHENOL, P-PHENYLENEDIAMINE | |
| Determined safe for use in cosmetics, subject to concentration or use limitations - any | 2-METHYL-5-HYDROXYETHYLAMINOPHENOL | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | P-PHENYLENEDIAMINE |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study | ISOPROPYL ACETATE | |
| One or more animal studies show brain and nervous system effects at moderate doses | P-AMINOPHENOL, AMINOMETHYL PROPANOL | |
| One or more animal studies show brain and nervous system effects at low doses | SODIUM SULFITE | |
| Moderate evidence of human neurotoxicity | FRAGRANCE | |
| One or more animal studies show brain and nervous system effects at very low doses | 1,2,4-TRIHYDROXYBENZENE | |
| Strong evidence of human neurotoxicity | P-PHENYLENEDIAMINE, ISOPROPYL ALCOHOL |
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show endocrine system disruption at high doses | P-PHENYLENEDIAMINE, N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE |
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Human immune system toxicant - moderate evidence | SODIUM SULFITE | |
| Human skin toxicant - strong evidence | N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE, 2-METHYL-5-HYDROXYETHYLAMINOPHENOL | |
| Known human immune system toxicant | P-PHENYLENEDIAMINE, P-AMINOPHENOL, FRAGRANCE |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient) | ERYTHORBIC ACID, AMINOMETHYL PROPANOL | |
| One or more animal studies show kidney or renal system effects at moderate doses (low dose studies may be unavailable for this ingredient) | TRISODIUM EDTA, | |
| One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient) | SULFURIC ACID | |
| One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient) | N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE | |
| Possible human immune system toxicant | SODIUM SULFITE | |
| Limited evidence of sense organ toxicity | ISOPROPYL ALCOHOL | |
| One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient) | 2-METHYL-5-HYDROXYETHYLAMINOPHENOL | |
| One or more animal studies show broad systemic effects at low doses | 1,2,4-TRIHYDROXYBENZENE | |
| Possible human immune system toxicant | P-AMINOPHENOL | |
| Known human respiratory toxicant | P-PHENYLENEDIAMINE |
*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Occupational hazards related to handling | SULFURIC ACID, ISOPROPYL ALCOHOL, ISOPROPYL ACETATE | |
| Ingredient not fully labeled - identity unknown | FRAGRANCE |
*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not suspected to be an environmental toxin | SULFURIC ACID, ISOPROPYL ALCOHOL | |
| Wildlife and environmental toxicity | P-PHENYLENEDIAMINE, P-AMINOPHENOL, AMINOMETHYL PROPANOL |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show skin irritation at high doses | SODIUM SULFITE | |
| One or more animal studies show skin irritation at moderate doses | P-AMINOPHENOL | |
| One or more animal studies show skin irritation at very low doses | 1,2,4-TRIHYDROXYBENZENE | |
| Classified as irritant | P-PHENYLENEDIAMINE, ISOPROPYL ALCOHOL, ISOPROPYL ACETATE, AMINOMETHYL PROPANOL |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Missing safety data noted by cosmetic industry review | P-PHENYLENEDIAMINE | |
| Insufficient data to determine safety | P-AMINOPHENOL, P-PHENYLENEDIAMINE | |
| Missing safety data noted by cosmetic industry review | P-AMINOPHENOL | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | TRISODIUM EDTA, SODIUM SULFITE, N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE, P-PHENYLENEDIAMINE, P-AMINOPHENOL, CARBOMER, ERYTHORBIC ACID | |
| Not assessed for safety in cosmetics by industry panel | SULFURIC ACID, 1,2,4-TRIHYDROXYBENZENE, ISOPROPYL ALCOHOL, ISOPROPYL ACETATE, FRAGRANCE, COCO-GLUCOSIDE, CINNAMIDOPROPYLTRIMONIUM CHLORIDE |
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to high doses | ISOPROPYL ALCOHOL, ISOPROPYL ACETATE | |
| Allowed workplace exposures restricted to low doses | P-AMINOPHENOL | |
| Allowed workplace exposures restricted to very low doses | SULFURIC ACID, P-PHENYLENEDIAMINE |
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood | P-AMINOPHENOL |
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