

Compact for Safe Cosmetics
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Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards |
Ingredients from packaging: No-Lye Conditioning Creme Relaxer: Water (Aqua), Petrolatum, Mineral Oil, Calcium Hydroxide, Lithium Hydroxide, Cetearyl Alcohol, Behentrimonium Methosulfate, PEG-75 Lanolin, Cocamidopropyl Betaine, Propylparaben Glycol, Polyquaternium-6, Quaternium-18 Hectorite, Propylene Carbonate, Aloe Barbadensis Leaf Juice, Fragrance (Parfum). No-Lye Liquid Activator: Water (Aqua), Guanidine Carbonate, Xanthan Gum, Pentasodium Pentetate, Sorbitol, Denatonium, Benzoate. Neutralizing Shampoo with Color Alert: Water (Aqua), Cocamidopropyl Betaine, Ammonium Lauryl Sulfate, Ammonium Laureth Sulfate, Cocamide DEA, Lauramide DEA, Citric Acid, Polysorbate-20, Fragrance (Parfum), Polyquaternium-7, Methylchloroisothiazolinone, Methylisothiazolinone, Phenolsulfonphtalein. Leave In Conditioner & Setting Styling Lotion: Water (Aqua), Polyquaternium-7, Oleth-20, Aloe Barbadensis Leaf Juice, Panthenol (Pro Vitamin B5), Silk Amino Acids (Protein), Rose Extract, Chamomile Extract, Geranium Extract, Rosemary Extract, Clary Extract, Sage Extract, Jasmine Extract, Citric Acid, Fragrance (Parfum), Methylchloroisothiazolinone, Methylisothiazolinone, Red No. 40 (CI 16035).
Warnings from packaging: Follow directions carefully to avoid skin and scalp burns, hair breakage, or eye injury. Do not use if scalp is irritated or injured. Do not apply to scalp. Do not use on bleached hair or hair that has been permed with ammonium thioglycolate (curl perm) or ammonium bisulfite. Do not use on permanently colored hair or hair which is breaking, splitting or otherwise damaged. If hair has been previously relaxed, apply only to new growth as described in the directions. If relaxer causes skin or scalp irritation, rinse out immediately, and wash with the shampoo in the kit. If irritation persists or if hair breakage occurs, consult a physician. If relaxer gets into eyes, rinse immediately, and consult a physician. Hair is flammable. Keep away from sparks and open flame at all times. Keep out of reach of children.
| score | data gap | concerns | |
| FRAGRANCE | 8 | 100% | Neurotoxicity, Allergies/immunotoxicity, Miscellaneous |
| PEG-75 LANOLIN | 4 | 75% | Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE) |
| METHYLCHLOROISOTHIAZOLINONE | 6 | 63% | Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive) |
| METHYLISOTHIAZOLINONE | 6 | 63% | Violations, restrictions & warnings, Allergies/immunotoxicity |
| COCAMIDE DEA | 6 | 61% | Cancer, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (NITROSAMINES) |
| PROPYLPARABEN | 5 | 71% | Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive) |
| COCAMIDOPROPYL BETAINE | 5 | 63% | Allergies/immunotoxicity, Contamination concerns (NITROSAMINES) |
| OLETH-20 | 3 | 87% | Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE) |
| LITHIUM HYDROXIDE | 4 | 86% | Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive) |
| MINERAL OIL | 2 | 73% | Organ system toxicity (non-reproductive), Occupational hazards |
| PROPYLENE GLYCOL PROPYLPARABEN GLYCOL | 4 | 60% | Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption |
| AMMONIUM LAURETH SULFATE | 3 | 87% | Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE) |
| CITRIC ACID | 2 | 72% | Violations, restrictions & warnings |
| LAURAMIDE DEA | 3 | 70% | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (NITROSAMINES) |
| PETROLATUM | 2 | 94% | Organ system toxicity (non-reproductive), Contamination concerns (PAHS) |
| POLYQUATERNIUM-7 | 2 | 93% | Contamination concerns (ACRYLAMIDE) |
| PANTHENOL | 2 | 88% | Multiple, additive exposure sources |
| POLYQUATERNIUM-6 | 2 | 87% | Persistence and bioaccumulation, Organ system toxicity (non-reproductive) |
| CALCIUM HYDROXIDE | 1 | 83% | Occupational hazards |
| JASMINUM OFFICINALE (JASMINE) EXTRACT | 2 | 76% | Violations, restrictions & warnings |
| SALVIA OFFICINALIS (SAGE) LEAF EXTRACT SAGE EXTRACT | 1 | 95% | none identified |
| CETEARYL ALCOHOL | 0 | 93% | none identified |
| DENATONIUM BENZOATE | 1 | 90% | none identified |
| BENZILIC ACID BENZOATE | 1 | 89% | none identified |
| GUANIDINE CARBONATE | 1 | 89% | none identified |
| PHENOLSULFONPHTHALEIN PHENOLSULFONPHTALEIN | 1 | 88% | Organ system toxicity (non-reproductive) |
| SORBITOL | 1 | 88% | none identified |
| PROPYLENE CARBONATE | 1 | 85% | Irritation (skin, eyes, or lungs) |
| FD&C RED 40 RED NO 40 (CI 16035) | 1 | 84% | none identified |
| POLYSORBATE-20 | 1 | 84% | none identified |
| ANTHEMIS NOBILIS (CHAMOMILE) EXTRACT | 1 | 80% | Enhanced skin absorption |
| PENTASODIUM PENTETATE | 0 | 74% | none identified |
| AMMONIUM LAURYL SULFATE | 1 | 73% | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| ALOE BARBADENSIS (ALOE VERA) GEL ALOE BARBADENSIS LEAF JUICE | 1 | 72% | none identified |
| BEHENTRIMONIUM METHOSULFATE | 0 | 100% | none identified |
| PELARGONIUM GRAVEOLENS (GERANIUM) EXTRACT | 0 | 100% | none identified |
| ROSMARINUS OFFICINALIS (ROSEMARY) LEAF EXTRACT ROSEMARY EXTRACT | 0 | 100% | none identified |
| SALVIA SCLAREA (CLARY SAGE) EXTRACT CLARY EXTRACT | 0 | 100% | none identified |
| ROSE EXTRACT | 0 | 100% | none identified |
| SILK AMINO ACIDS | 0 | 100% | none identified |
| QUATERNIUM-18 HECTORITE | 0 | 99% | none identified |
| XANTHAN GUM | 0 | 94% | none identified |
| WATER | 0 | 0% | innocuous |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show tumor formation at high doses | MINERAL OIL, LAURAMIDE DEA | |
| One or more in vitro tests non-mammalian cells show positive mutation results | PHENOLSULFONPHTHALEIN | |
| One or more in vitro tests on mammalian cells show positive mutation results | SALVIA OFFICINALIS (SAGE) LEAF EXTRACT, SORBITOL | |
| One or more in vitro tests non-mammalian cells show positive mutation results | METHYLCHLOROISOTHIAZOLINONE | |
| One or more in vitro tests on mammalian cells show positive mutation results | PROPYLPARABEN, PROPYLENE GLYCOL, FD&C RED 40, CALCIUM HYDROXIDE | |
| Cancer - limited evidence | COCAMIDE DEA |
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show reproductive effects at high doses | POLYSORBATE-20, FD&C RED 40 | |
| One or more animal studies show reproductive effects at moderate doses | PROPYLENE GLYCOL, | |
| One or more animal studies show any effects at moderate doses | ALOE BARBADENSIS (ALOE VERA) GEL | |
| One or more animal studies show any effects at low doses | PROPYLPARABEN | |
| Human nervous system toxicant - moderate evidence | LITHIUM HYDROXIDE |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | METHYLCHLOROISOTHIAZOLINONE, METHYLISOTHIAZOLINONE | |
| Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Fragrance subject to restrictions: safe only within recommended use or concentration limitsn) | JASMINUM OFFICINALE (JASMINE) EXTRACT | |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | METHYLISOTHIAZOLINONE, PROPYLENE GLYCOL, PEG-75 LANOLIN, METHYLCHLOROISOTHIAZOLINONE, LAURAMIDE DEA, COCAMIDOPROPYL BETAINE, COCAMIDE DEA, AMMONIUM LAURYL SULFATE, ALOE BARBADENSIS (ALOE VERA) GEL | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - prohibited for use in some types of cosmetics when combined with certain other ingredients | METHYLCHLOROISOTHIAZOLINONE, CITRIC ACID, METHYLISOTHIAZOLINONE, METHYLCHLOROISOTHIAZOLINONE |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more in vitro tests on mammalian cells demonstrate neurotoxicity | METHYLISOTHIAZOLINONE | |
| One or more animal studies show brain and nervous system effects at moderate doses | ANTHEMIS NOBILIS (CHAMOMILE) EXTRACT | |
| One or more animal studies show brain and nervous system effects at high doses | PROPYLENE GLYCOL | |
| One or more animal studies show brain and nervous system effects at moderate doses | DENATONIUM BENZOATE, POLYQUATERNIUM-6 | |
| Strong evidence of human neurotoxicity | LITHIUM HYDROXIDE | |
| Moderate evidence of human neurotoxicity | FRAGRANCE |
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Human any disruptor - strong evidence | PROPYLPARABEN | |
| One or more animal studies show endocrine system disruption at high doses | ANTHEMIS NOBILIS (CHAMOMILE) EXTRACT |
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Known human immune system toxicant | METHYLISOTHIAZOLINONE | |
| Limited evidence of skin and immune system toxicity | PROPYLENE GLYCOL | |
| Human skin toxicant - strong evidence | PROPYLPARABEN | |
| Known human immune system toxicant | METHYLCHLOROISOTHIAZOLINONE, FRAGRANCE, COCAMIDOPROPYL BETAINE, COCAMIDE DEA |
*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not suspected to be bioaccumulative | POLYQUATERNIUM-6, PETROLATUM |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Classified as expected to be toxic or harmful | PETROLATUM, AMMONIUM LAURYL SULFATE | |
| One or more animal studies show metabolic effects at high doses (low dose studies may be unavailable for this ingredient) | PROPYLENE GLYCOL, FD&C RED 40, ANTHEMIS NOBILIS (CHAMOMILE) EXTRACT, POLYQUATERNIUM-6, COCAMIDE DEA, SORBITOL, POLYSORBATE-20, PANTHENOL, CALCIUM HYDROXIDE, MINERAL OIL | |
| One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient) | OLETH-20, CITRIC ACID, GUANIDINE CARBONATE, BENZILIC ACID, LAURAMIDE DEA, AMMONIUM LAURETH SULFATE, ALOE BARBADENSIS (ALOE VERA) GEL | |
| One or more animal studies show kidney or renal system effects at very low doses | PHENOLSULFONPHTHALEIN | |
| Limited evidence of sense organ toxicity | PEG-75 LANOLIN, PROPYLPARABEN | |
| One or more animal studies show liver effects at low doses | LITHIUM HYDROXIDE | |
| Possible human immune system toxicant | METHYLCHLOROISOTHIAZOLINONE |
*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Ingredient not fully labeled - identity unknown | FRAGRANCE |
*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Designated as safe for general or specific, limited use in food | PEG-75 LANOLIN, XANTHAN GUM, SORBITOL, ROSMARINUS OFFICINALIS (ROSEMARY) LEAF EXTRACT, PROPYLPARABEN, PROPYLENE GLYCOL, POLYSORBATE-20, PETROLATUM, MINERAL OIL, LAURAMIDE DEA, FD&C RED 40, COCAMIDE DEA, CITRIC ACID, CALCIUM HYDROXIDE, ALOE BARBADENSIS (ALOE VERA) GEL | |
| Used in food or as an additive with limited or no toxicity information available | PANTHENOL |
*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Suspected to be an environmental toxin | POLYQUATERNIUM-6 | |
| Not suspected to be an environmental toxin | PETROLATUM | |
| Wildlife and environmental toxicity | PROPYLPARABEN |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show skin irritation at moderate doses | POLYSORBATE-20, ANTHEMIS NOBILIS (CHAMOMILE) EXTRACT, MINERAL OIL, CITRIC ACID | |
| One or more animal studies show skin irritation at low doses | OLETH-20, COCAMIDE DEA | |
| One or more animal studies show skin irritation at very low doses | LAURAMIDE DEA, AMMONIUM LAURYL SULFATE | |
| Human any irritant - strong evidence | products for use around the eyes, on the skin, or may be aerosolized (airborne) | AMMONIUM LAURETH SULFATE |
| Classified as skin irritant | PROPYLENE GLYCOL, PROPYLENE CARBONATE |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Safety assessment was based on related chemical | OLETH-20, PEG-75 LANOLIN | |
| Missing safety data noted by cosmetic industry review | ALOE BARBADENSIS (ALOE VERA) GEL, PENTASODIUM PENTETATE | |
| Safety assessment was based on related chemical | PROPYLENE GLYCOL, PENTASODIUM PENTETATE | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | PEG-75 LANOLIN, ANTHEMIS NOBILIS (CHAMOMILE) EXTRACT, CETEARYL ALCOHOL, LAURAMIDE DEA, PANTHENOL, OLETH-20, QUATERNIUM-18 HECTORITE, PROPYLPARABEN, PROPYLENE CARBONATE, POLYSORBATE-20, POLYQUATERNIUM-7, PENTASODIUM PENTETATE | |
| Not assessed for safety in cosmetics by industry panel | SILK AMINO ACIDS, ANTHEMIS NOBILIS (CHAMOMILE) EXTRACT | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | AMMONIUM LAURETH SULFATE | |
| Not assessed for safety in cosmetics by industry panel | ROSE EXTRACT, XANTHAN GUM, SORBITOL, SALVIA SCLAREA (CLARY SAGE) EXTRACT, SALVIA OFFICINALIS (SAGE) LEAF EXTRACT, ROSMARINUS OFFICINALIS (ROSEMARY) LEAF EXTRACT, POLYQUATERNIUM-6, PHENOLSULFONPHTHALEIN, PETROLATUM, PELARGONIUM GRAVEOLENS (GERANIUM) EXTRACT, MINERAL OIL, LITHIUM HYDROXIDE, JASMINUM OFFICINALE (JASMINE) EXTRACT, GUANIDINE CARBONATE, FRAGRANCE, BENZILIC ACID, DENATONIUM BENZOATE, CITRIC ACID, CALCIUM HYDROXIDE, BEHENTRIMONIUM METHOSULFATE |
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to moderate doses | MINERAL OIL | |
| No workplace limits set | LITHIUM HYDROXIDE | |
| Allowed workplace exposures restricted to moderate doses | CALCIUM HYDROXIDE |
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood | LAURAMIDE DEA | |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | CITRIC ACID, PROPYLENE GLYCOL |
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