Superior Preference Ultra Long-Lasting Color and Shine System, Level 3 Permanent, Intense Dark Red RRO4 || Skin Deep: Cosmetic Safety Reviews

SUPERIOR PREFERENCE ULTRA LONG-LASTING COLOR AND SHINE SYSTEM, LEVEL 3 PERMANENT, INTENSE DARK RED RRO4

last updated: 02/01/08 brand: Superior Preference by L'Oréal

SCORE

high hazard (out of 10)

77%

data gap

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98% of lipsticks have lower concerns

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company conducts animal tests.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes

Ingredients from packaging: Color Gel: Water, Trideceth-2 Carboxamide MEA, Propylene Glycol, Hexylene Glycol, PEG-2 Oleamine, Polyglyceryl-4 Oleyl Ether, Oleyl Alcohol, Alcohol Denat., Ammonium Hydroxide, Polyglyceryl-2 Oleyl Ether, Oleic Acid, Sodium Diethylaminopropyl Cocoaspartamide, Pentasodium Pentetate, Ammonium Acetate, Fragrance, 2-Methyl-5-Hydroxyethylaminophenol, 4-Amino-2-Hydroxytoluene, P-Phenylenediamine, Sodium Metabisulfite, P-Aminophenol, Erythorbic Acid, Resorcinol, Phenyl Methyl Pyrazolone, P-Methylaminophenol Sulfate, 6-Hydroxyindole. Color Optimizing Creme: Water, Hydrogen Peroxide, Cetearyl Alcohol, Trideceth-2 Carboxamide MEA, Ceteareth-30, Glycerin, Pentasodium Pentetate, Sodium Stannate, Tetrasodium Pyrophosphate. Care Supreme Conditioner: Water, Cetearyl Alcohol, Glycerin, Behentrimonium Chloride, Euphorbia Cerifera (Candelilla) Wax, Amodimethicone, Cetyl Esters, Isopropyl Alcohol, Fragrance, Methylparaben, Camphor Benzalkonium Methosulfate, Trideceth-12, Chlorhexidine Dihydrochloride, Cetrimonium Chloride, PPG-5 Ceteth-20, Oleth-10, Disodium Cocoamphodipropionate, Lecithin, Phosphoric Acid, Tocopherol, Ethylhexyl Salicylate, Phenoxyethanol, Ethylparaben.

Directions from packaging: Follow the instructions. Store between 50 and 80 degrees F.

Warnings from packaging: Haircolor products can cause an allergic reaction which, in certain rare cases, can be serious. Therefore, before you use this product it is necessary to follow these precautions: Do not use if you have already had a reaction to a haircolor product; if you have a sensitive, itchy or damaged scalp. Perform an allergy test with a portion of this product 48 hours before full application (see the instruction sheet). Avoid contact with eyes and skin (other than areas of application). If product gets into eyes, rinse with lukewarm water immediately. Wear gloves provided in kit. Thoroughly rinse hair after application. Do not use for anything other than coloring your hair. Wait at least 14 days after bleaching, perming, or relaxing before coloring. Do not use over compound henna or progressive color. Do not inhale or ingest. Keep product out of the reach of children. This product contains ingredients which may cause skin irritation on certain individuals and a preliminary test according to accompanying directions should first be made. This product must not be used for dyeing the eyelashes or eyebrows; to do so may cause blindness.

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ingredients

	score	data gap	concerns
METHYLPARABEN	10	63%	Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes
P-PHENYLENEDIAMINE	10	52%	Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
RESORCINOL	10	52%	Cancer, Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
P-AMINOPHENOL	8	57%	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards
FRAGRANCE	8	100%	Neurotoxicity, Allergies/immunotoxicity, Miscellaneous
CETEARETH-30	5	71%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
PEG-2 OLEAMINE	4	75%	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
LECITHIN	3	70%	Multiple, additive exposure sources, Enhanced skin absorption, Contamination concerns (NITROSAMINES)
SODIUM METABISULFITE	6	70%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
HYDROGEN PEROXIDE	6	65%	Violations, restrictions & warnings, Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
P-METHYLAMINOPHENOL SULFATE	6	60%	Cancer, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards
ETHYLPARABEN	5	80%	Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
CHLORHEXIDINE DIHYDROCHLORIDE	4	73%	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
ALCOHOL DENATURED	5	71%	Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards
PHENYL METHYL PYRAZOLONE	5	68%	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity
4-AMINO-2-HYDROXYTOLUENE	5	67%	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity
HEXYLENE GLYCOL	5	67%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
DISODIUM COCOAMPHODIPROPIONATE	5	63%	Allergies/immunotoxicity, Contamination concerns (NITROSAMINES)
OLETH-10	4	87%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
ISOPROPYL ALCOHOL	4	72%	Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
OCTISALATE ETHYLHEXYL SALICYLATE (Active Ingredient)	3	68%	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Enhanced skin absorption
6-HYDROXYINDOLE	2	67%	Cancer, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
PHENOXYETHANOL	4	67%	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
PROPYLENE GLYCOL	4	60%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
PPG-5-CETETH-20	3	93%	Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
2-METHYL-5-HYDROXYETHYLAMINOPHENOL	3	73%	Cancer, Allergies/immunotoxicity
CETRIMONIUM CHLORIDE	3	71%	Allergies/immunotoxicity
TOCOPHEROL	2	87%	Contamination concerns (HYDROQUINONE)
AMMONIUM ACETATE	2	82%	none identified
OLEIC ACID	1	82%	Irritation (skin, eyes, or lungs)
TETRASODIUM PYROPHOSPHATE	2	82%	Neurotoxicity, Organ system toxicity (non-reproductive), Occupational hazards
AMMONIUM HYDROXIDE	2	81%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
PHOSPHORIC ACID	2	79%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
GLYCERIN	2	74%	Organ system toxicity (non-reproductive), Occupational hazards
BEHENTRIMONIUM CHLORIDE	0	94%	none identified
CETEARYL ALCOHOL	0	93%	none identified
SODIUM STANNATE	1	88%	Occupational hazards
TRIDECETH-12	1	88%	Organ system toxicity (non-reproductive)
ERYTHORBIC ACID	1	87%	none identified
OLEYL ALCOHOL	1	87%	Irritation (skin, eyes, or lungs)
PENTASODIUM PENTETATE	0	74%	none identified
CAMPHOR BENZALKONIUM METHOSULFATE	0	100%	none identified
POLYGLYCERYL-2 OLEYL ETHER	0	100%	none identified
POLYGLYCERYL-4 OLEYL ETHER	0	100%	none identified
SODIUM DIETHYLAMINOPROPYL COCOASPARTAMIDE	0	100%	none identified
TRIDECETH-2 CARBOXAMIDE MEA	0	100%	none identified
AMODIMETHICONE	0	99%	none identified
EUPHORBIA CERIFERA (CANDELILLA) WAX	0	93%	none identified
CETYL ESTERS	0	93%	none identified
WATER	0	0%	innocuous

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more in vitro tests on mammalian cells show positive mutation results		GLYCERIN, METHYLPARABEN, OLEIC ACID, PROPYLENE GLYCOL, SODIUM METABISULFITE, TOCOPHEROL
One or more in vitro tests non-mammalian cells show positive mutation results		AMMONIUM HYDROXIDE, PHENOXYETHANOL
One or more in vitro tests on mammalian cells show positive mutation results		ETHYLPARABEN, ERYTHORBIC ACID, CETRIMONIUM CHLORIDE
Cancer - not classifiable/not likely to be human carcinogen		AMMONIUM ACETATE
Cancer - limited evidence		PHENYL METHYL PYRAZOLONE, P-METHYLAMINOPHENOL SULFATE, ALCOHOL DENATURED, 6-HYDROXYINDOLE, 4-AMINO-2-HYDROXYTOLUENE, 2-METHYL-5-HYDROXYETHYLAMINOPHENOL
Mutagen - limited evidence		P-AMINOPHENOL
Cancer - not classifiable/not likely to be human carcinogen		RESORCINOL, P-PHENYLENEDIAMINE, ISOPROPYL ALCOHOL, HYDROGEN PEROXIDE

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive effects at high doses		SODIUM METABISULFITE, PHENYL METHYL PYRAZOLONE, ETHYLPARABEN
One or more animal studies show reproductive effects at moderate doses		PROPYLENE GLYCOL, P-AMINOPHENOL, GLYCERIN
Limited evidence of developmental toxicity		ISOPROPYL ALCOHOL, ALCOHOL DENATURED
Human nervous system toxicant - moderate evidence		P-PHENYLENEDIAMINE

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		PROPYLENE GLYCOL, PEG-2 OLEAMINE, DISODIUM COCOAMPHODIPROPIONATE, CHLORHEXIDINE DIHYDROCHLORIDE, CETRIMONIUM CHLORIDE, P-PHENYLENEDIAMINE, PHENYL METHYL PYRAZOLONE, RESORCINOL, LECITHIN, 2-METHYL-5-HYDROXYETHYLAMINOPHENOL, 4-AMINO-2-HYDROXYTOLUENE, 6-HYDROXYINDOLE, P-AMINOPHENOL, P-METHYLAMINOPHENOL SULFATE, CETEARETH-30
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel		P-PHENYLENEDIAMINE, PHENYL METHYL PYRAZOLONE, P-AMINOPHENOL, 4-AMINO-2-HYDROXYTOLUENE
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		P-PHENYLENEDIAMINE
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics	products for use on the lips	HYDROGEN PEROXIDE
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		CHLORHEXIDINE DIHYDROCHLORIDE, OCTISALATE, CHLORHEXIDINE DIHYDROCHLORIDE, RESORCINOL, PHENOXYETHANOL
Violation of government restrictions - Banned or found unsafe for use in cosmetics	product not intended as hair dye/bleach	HYDROGEN PEROXIDE
Violation of government restrictions - Banned or found unsafe for use in cosmetics		METHYLPARABEN

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show brain and nervous system effects at high doses		PHENYL METHYL PYRAZOLONE, PROPYLENE GLYCOL
nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study		HEXYLENE GLYCOL
One or more animal studies show brain and nervous system effects at high doses		GLYCERIN, 4-AMINO-2-HYDROXYTOLUENE
One or more animal studies show brain and nervous system effects at moderate doses		SODIUM METABISULFITE, RESORCINOL, PHOSPHORIC ACID, PHENOXYETHANOL, P-AMINOPHENOL, OLEIC ACID, METHYLPARABEN, LECITHIN, AMMONIUM ACETATE, CETEARETH-30
One or more animal studies show brain and nervous system effects at low doses		TETRASODIUM PYROPHOSPHATE
Moderate evidence of human neurotoxicity		FRAGRANCE
One or more animal studies show brain and nervous system effects at very low doses		HYDROGEN PEROXIDE
Strong evidence of human neurotoxicity		ISOPROPYL ALCOHOL, P-PHENYLENEDIAMINE

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show endocrine system disruption at high doses		HYDROGEN PEROXIDE, P-PHENYLENEDIAMINE, HEXYLENE GLYCOL, ALCOHOL DENATURED, GLYCERIN, 4-AMINO-2-HYDROXYTOLUENE
One or more animal studies show endocrine disruption at moderate doses		AMMONIUM ACETATE
Human any disruptor - strong evidence		METHYLPARABEN, RESORCINOL, ETHYLPARABEN

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Limited evidence of skin and immune system toxicity		PHENOXYETHANOL
One or more human case studies show possible immune effects		OCTISALATE
Human immune system toxicant - moderate evidence		CHLORHEXIDINE DIHYDROCHLORIDE
Limited evidence of skin and immune system toxicity		PROPYLENE GLYCOL
Human skin toxicant - strong evidence		PHENYL METHYL PYRAZOLONE, METHYLPARABEN, ETHYLPARABEN, CETRIMONIUM CHLORIDE, 4-AMINO-2-HYDROXYTOLUENE, 2-METHYL-5-HYDROXYETHYLAMINOPHENOL
Known human immune system toxicant		SODIUM METABISULFITE, RESORCINOL, P-PHENYLENEDIAMINE, P-METHYLAMINOPHENOL SULFATE, P-AMINOPHENOL, HEXYLENE GLYCOL, FRAGRANCE, DISODIUM COCOAMPHODIPROPIONATE

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not suspected to be bioaccumulative		SODIUM METABISULFITE, PHOSPHORIC ACID, ISOPROPYL ALCOHOL, AMMONIUM HYDROXIDE
Not suspected to be persistent		TRIDECETH-12
Not suspected to be bioaccumulative		ALCOHOL DENATURED

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient)		TRIDECETH-12
One or more animal studies show sense organ effects at moderate doses (low dose studies may be unavailable for this ingredient)	products for use around the eyes, mouth, or lips	OLEYL ALCOHOL, PHENYL METHYL PYRAZOLONE, PROPYLENE GLYCOL
One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient)		ERYTHORBIC ACID
One or more animal studies show sense organ effects at moderate doses (low dose studies may be unavailable for this ingredient)	products for use around the eyes, mouth, or lips	OLEIC ACID
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		CETRIMONIUM CHLORIDE, OCTISALATE, AMMONIUM ACETATE, 2-METHYL-5-HYDROXYETHYLAMINOPHENOL, 4-AMINO-2-HYDROXYTOLUENE
Limited evidence of sense organ toxicity		PEG-2 OLEAMINE, ETHYLPARABEN
Classified as toxic or harmful	products for use around the mouth; products for use on the lips	P-METHYLAMINOPHENOL SULFATE, 6-HYDROXYINDOLE
One or more animal studies show sense organ effects at low doses	products for use around the eyes, mouth, or lips	OLETH-10, CETEARETH-30
One or more animal studies show metabolic effects at low doses		TETRASODIUM PYROPHOSPHATE
One or more animal studies show sense organ effects at very low doses	products for use around the eyes, mouth, or lips	RESORCINOL, PHOSPHORIC ACID, PHENOXYETHANOL, ISOPROPYL ALCOHOL, AMMONIUM HYDROXIDE, HEXYLENE GLYCOL, HYDROGEN PEROXIDE, ALCOHOL DENATURED
One or more animal studies show kidney or renal system effects at very low doses		GLYCERIN
Possible human immune system toxicant		SODIUM METABISULFITE, CHLORHEXIDINE DIHYDROCHLORIDE, P-AMINOPHENOL
Known human respiratory toxicant		P-PHENYLENEDIAMINE, METHYLPARABEN

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Occupational hazards related to handling		SODIUM METABISULFITE, PHOSPHORIC ACID, HYDROGEN PEROXIDE, ISOPROPYL ALCOHOL, ALCOHOL DENATURED, AMMONIUM HYDROXIDE
Ingredient not fully labeled - identity unknown		FRAGRANCE

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Designated as safe for general or specific, limited use in food		TOCOPHEROL, TETRASODIUM PYROPHOSPHATE, RESORCINOL, PROPYLENE GLYCOL, PHOSPHORIC ACID, METHYLPARABEN, PEG-2 OLEAMINE, OLEIC ACID, LECITHIN, ISOPROPYL ALCOHOL, HYDROGEN PEROXIDE, GLYCERIN, ERYTHORBIC ACID, CHLORHEXIDINE DIHYDROCHLORIDE, EUPHORBIA CERIFERA (CANDELILLA) WAX, AMMONIUM HYDROXIDE, SODIUM METABISULFITE, AMMONIUM ACETATE, ALCOHOL DENATURED
Used in food or as an additive with limited or no toxicity information available		LECITHIN, ALCOHOL DENATURED

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Suspected to be an environmental toxin		TRIDECETH-12
Not suspected to be an environmental toxin		SODIUM METABISULFITE, PHOSPHORIC ACID, ISOPROPYL ALCOHOL, ALCOHOL DENATURED
Wildlife and environmental toxicity		P-PHENYLENEDIAMINE, RESORCINOL, P-METHYLAMINOPHENOL SULFATE, P-AMINOPHENOL, AMMONIUM HYDROXIDE, 6-HYDROXYINDOLE

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show skin irritation at moderate doses		TRIDECETH-12
One or more animal studies show skin irritation at high doses		4-AMINO-2-HYDROXYTOLUENE, P-METHYLAMINOPHENOL SULFATE
One or more animal studies show skin irritation at moderate doses		P-AMINOPHENOL, GLYCERIN
One or more animal studies show skin irritation at low doses		OLETH-10, OLEIC ACID, OCTISALATE, METHYLPARABEN, CETEARETH-30, ALCOHOL DENATURED
One or more animal studies show skin irritation at very low doses		OLEYL ALCOHOL
Human skin irritant - moderate evidence		PHOSPHORIC ACID, CHLORHEXIDINE DIHYDROCHLORIDE, HYDROGEN PEROXIDE
Classified as skin irritant		PROPYLENE GLYCOL
Human skin irritant - moderate evidence		AMMONIUM HYDROXIDE
Classified as irritant		RESORCINOL, SODIUM METABISULFITE, PHENOXYETHANOL, ISOPROPYL ALCOHOL, P-PHENYLENEDIAMINE, 6-HYDROXYINDOLE, HEXYLENE GLYCOL

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Safety assessment was based on related chemical		AMODIMETHICONE, PROPYLENE GLYCOL
Insufficient data to determine safety		P-PHENYLENEDIAMINE, PHENYL METHYL PYRAZOLONE
Safety assessment was based on related chemical		OLETH-10, CETYL ESTERS, PPG-5-CETETH-20, PENTASODIUM PENTETATE
Missing safety data noted by cosmetic industry review		PHENYL METHYL PYRAZOLONE
Insufficient data to determine safety		AMMONIUM ACETATE, 4-AMINO-2-HYDROXYTOLUENE, ALCOHOL DENATURED, P-AMINOPHENOL
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		PHENYL METHYL PYRAZOLONE, RESORCINOL
Missing safety data noted by cosmetic industry review		PENTASODIUM PENTETATE, P-PHENYLENEDIAMINE, 4-AMINO-2-HYDROXYTOLUENE, P-AMINOPHENOL
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		TOCOPHEROL
Considered safe based on assumption of low absorption		4-AMINO-2-HYDROXYTOLUENE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		SODIUM METABISULFITE, PHENOXYETHANOL, PENTASODIUM PENTETATE, P-PHENYLENEDIAMINE, P-AMINOPHENOL, P-METHYLAMINOPHENOL SULFATE, OLEYL ALCOHOL, METHYLPARABEN, OLEIC ACID, OLETH-10, HEXYLENE GLYCOL, ETHYLPARABEN, ERYTHORBIC ACID, CETYL ESTERS, DISODIUM COCOAMPHODIPROPIONATE, CETEARYL ALCOHOL, EUPHORBIA CERIFERA (CANDELILLA) WAX, AMODIMETHICONE, 4-AMINO-2-HYDROXYTOLUENE
Not assessed for safety in cosmetics by industry panel		TRIDECETH-12, TRIDECETH-2 CARBOXAMIDE MEA, TETRASODIUM PYROPHOSPHATE, SODIUM STANNATE, SODIUM DIETHYLAMINOPROPYL COCOASPARTAMIDE, PPG-5-CETETH-20, POLYGLYCERYL-4 OLEYL ETHER, POLYGLYCERYL-2 OLEYL ETHER, PHOSPHORIC ACID, PEG-2 OLEAMINE, OCTISALATE, ISOPROPYL ALCOHOL, HYDROGEN PEROXIDE, GLYCERIN, FRAGRANCE, CAMPHOR BENZALKONIUM METHOSULFATE, AMMONIUM HYDROXIDE, BEHENTRIMONIUM CHLORIDE, 6-HYDROXYINDOLE, AMMONIUM ACETATE

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to low doses		PHENOXYETHANOL, RESORCINOL, SODIUM METABISULFITE
Allowed workplace exposures restricted to low doses		PHOSPHORIC ACID, SODIUM STANNATE
Allowed workplace exposures restricted to moderate doses		GLYCERIN, TETRASODIUM PYROPHOSPHATE
Allowed workplace exposures restricted to high doses		ISOPROPYL ALCOHOL,
Allowed workplace exposures restricted to high doses		ALCOHOL DENATURED
Allowed workplace exposures restricted to very low doses		P-PHENYLENEDIAMINE
Allowed workplace exposures restricted to low doses		6-HYDROXYINDOLE, HYDROGEN PEROXIDE, P-AMINOPHENOL, P-METHYLAMINOPHENOL SULFATE

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood		P-AMINOPHENOL, SODIUM METABISULFITE
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		ALCOHOL DENATURED, GLYCERIN, HYDROGEN PEROXIDE, PROPYLENE GLYCOL
Interferes with gene expresion		METHYLPARABEN
Does not produces excess reactive oxygen species or other harmful biochemical changes.		OCTISALATE