L'Oréal Couleur Experte Multi-Tonal Color System, Permanent Color, Light Iridescent Brown/Cooler 6.2 || Skin Deep: Cosmetic Safety Reviews

L'ORéAL COULEUR EXPERTE MULTI-TONAL COLOR SYSTEM, PERMANENT COLOR, LIGHT IRIDESCENT BROWN/COOLER 6.2

last updated: 02/01/08 brand: L'Oréal by L'Oréal

SCORE

high hazard (out of 10)

79%

data gap

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83% of hair color and bleachings have lower concerns

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company conducts animal tests.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes

Ingredients from packaging: Multi-Tonal Gel Creme Color Base: Aqua/Water, Deceth-3, Laureth-12, Oleth-30, Deceth-5, Trideceth-2 Carboxamide MEA, Ammonium Hydroxide, Glycerin, Oleic Acid, Hexadimethrine Chloride, Oleyl Alcohol, Polyquaternium-6, Parfum/Fragrance, Ethanolamine, Resorcinol, Ammonium Thiolactate, Limonene, P-Phenylenediamine, Ascorbic Acid, EDTA, M-Aminophenol, Polyquaternium-24, Linalool, 2-Methylresorcinol, P-Aminophenol, Geraniol, 6-Hydroxyindole, 4-Amino-2-Hydroxytoluene, 2,4-Diaminophenoxyethanol HCl, Citronellol. Micro-Fine Illuminating Powder: Potassium Persulfate, Sodium Silicate, Sodium Persulfate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Urea, Kaolin, Magnesium Stearate, Ammonium Chloride, Diethylhexyl Sodium Sulfosuccinate, VP/VA Copolymer, Polydecene, Sodium Metasilicate, Magnesium Peroxide, EDTA, CI 77891/Titanium Dioxide, Cyamopsis Tetragonoloba/Guar Gum, Sodium Carboxymethyl Starch, Sodium Benzoate. Multi-Tonal/Illuminating Creme Developer: Aqua/Water, Hydrogen Peroxide, Cetearyl Alcohol, Trideceth-2 Carboxamide MEA, Ceteareth-30, Glycerin, Pentasodium Pentetate, Sodium Stannate, Tetrasodium Pyrophosphate. Multi-Moisture Creme Conditioner: Aqua/Water, Cetearyl Alcohol, Glycerin, Behentrimonium Chloride, Candelilla Cera/Candelilla Wax, Amodimethicone, Cetyl Esters, Isopropyl Alcohol, Trideceth-12, Chlorhexidine Dihydrochloride, Methylparaben, Cetrimonium Chloride, Prunus Armeniaca/Apricot Kernel Oil, Parfum/Fragrance.

Directions from packaging: Read and follow the insert. Store between 50 - 80 degrees F.

Warnings from packaging: Haircolor can cause an allergic reaction which, in certain rare cases, can be serious. Therefore, you must follow these precautions: Do not use if you have already had a reaction to a haircolor or hair lightening product; you have a sensitive, itchy or damaged scalp. Perform a skin allergy test 48 hours before each use of this product (see insert). Remember to buy your product 2 days ahead of time. Avoid contact of this product with eyes and skin. If product gets into eyes, rinse immediately. Wear gloves provided in kit. Thoroughly rinse hair after application. Do not use on relaxed hair or after bleaching your hair. Do not use over compound henna or progressive color. Do not inhale or ingest. Keep product out of the reach of children. Do not apply on children. This product contains ingredients which may cause skin irritation on certain individuals and a preliminary test according to accompanying directions should first be made. This product must not be used for dyeing the eyelashes or eyebrows; to do so may cause blindness. This product contains persulfates and other ingredients which may cause serious irritant, respiratory and/or allergic reactions. Prepare and use only in a well-ventilated area. Insert contains important health and safety information.

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ingredients

	score	data gap	concerns
METHYLPARABEN	10	63%	Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes
P-PHENYLENEDIAMINE	10	52%	Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
RESORCINOL	10	52%	Cancer, Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
P-AMINOPHENOL	8	57%	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards
FRAGRANCE	8	100%	Neurotoxicity, Allergies/immunotoxicity, Miscellaneous
CETEARETH-30	5	71%	Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
ETHANOLAMINE	7	66%	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
POTASSIUM PERSULFATE	6	66%	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Occupational hazards
SODIUM PERSULFATE	6	69%	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards
HYDROGEN PEROXIDE	3	65%	Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
M-AMINOPHENOL	6	65%	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Occupational hazards
GERANIOL	6	61%	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
LIMONENE	6	56%	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
CHLORHEXIDINE DIHYDROCHLORIDE	4	73%	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
4-AMINO-2-HYDROXYTOLUENE	5	67%	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity
LINALOOL	5	66%	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
CITRONELLOL	4	65%	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
OLETH-30	3	87%	Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
TITANIUM DIOXIDE (NON-NANO) CI 77891/TITANIUM DIOXIDE	1	81%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards, Biochemical or cellular level changes
ISOPROPYL ALCOHOL	4	72%	Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
6-HYDROXYINDOLE	3	67%	Cancer, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Occupational hazards
UREA	4	67%	Violations, restrictions & warnings, Irritation (skin, eyes, or lungs), Enhanced skin absorption
SODIUM METASILICATE	4	64%	Developmental/reproductive toxicity, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
LAURETH-12	3	100%	Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
CYAMOPSIS TETRAGONOLOBA (GUAR) GUM	1	79%	none identified
EDTA	3	78%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
AMMONIUM CHLORIDE	3	77%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
CETRIMONIUM CHLORIDE	3	71%	Allergies/immunotoxicity
SODIUM SILICATE	3	70%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
POLYQUATERNIUM-6	2	87%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive)
2-METHYLRESORCINOL	2	84%	Allergies/immunotoxicity
OLEIC ACID	1	82%	Irritation (skin, eyes, or lungs)
TETRASODIUM PYROPHOSPHATE	2	82%	Neurotoxicity, Organ system toxicity (non-reproductive), Occupational hazards
AMMONIUM HYDROXIDE	2	81%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
DIOCTYL SODIUM SULFOSUCCINATE DIETHYLHEXYL SODIUM SULFOSUCCINATE	2	81%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
KAOLIN	1	79%	Occupational hazards
MAGNESIUM PEROXIDE	0	76%	none identified
GLYCERIN	2	74%	Organ system toxicity (non-reproductive), Occupational hazards
SODIUM BENZOATE	2	69%	Organ system toxicity (non-reproductive)
BEHENTRIMONIUM CHLORIDE	0	94%	none identified
SODIUM CARBOXYMETHYL STARCH	0	94%	none identified
CETEARYL ALCOHOL	0	93%	none identified
ASCORBIC ACID (VITAMIN C)	1	91%	none identified
VP/ VA COPOLYMER	1	89%	none identified
DECETH-5	1	88%	Irritation (skin, eyes, or lungs)
SODIUM STANNATE	1	88%	Occupational hazards
TRIDECETH-12	1	88%	Organ system toxicity (non-reproductive)
OLEYL ALCOHOL	1	87%	Irritation (skin, eyes, or lungs)
MAGNESIUM STEARATE	1	83%	Occupational hazards
2,4-DIAMINOPHENOXYETHANOL HCL	1	75%	Cancer
PENTASODIUM PENTETATE	0	74%	none identified
ACRYLATES/ C10-30 ALKYL ACRYLATE CROSSPOLYMER	0	100%	none identified
DECETH-3	0	100%	none identified
HEXADIMETHRINE CHLORIDE	0	100%	none identified
POLYDECENE	0	100%	none identified
TRIDECETH-2 CARBOXAMIDE MEA	0	100%	none identified
AMMONIUM THIOLACTATE	0	100%	none identified
KYOUNIN YU PRUNUS ARMENIACA/APRICOT KERNEL OIL	0	100%	none identified
AMODIMETHICONE	0	99%	none identified
POLYQUATERNIUM-24	0	94%	none identified
PRUNUS ARMENIACA (APRICOT) KERNEL OIL	0	94%	none identified
PRUNUS ARMENIACA (APRICOT) OIL PRUNUS ARMENIACA/APRICOT KERNEL OIL	0	94%	none identified
EUPHORBIA CERIFERA (CANDELILLA) WAX CANDELILLA CERA/CANDELILLA WAX	0	93%	none identified
CETYL ESTERS	0	93%	none identified
WATER	0	0%	innocuous

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show tumor formation at high doses		CYAMOPSIS TETRAGONOLOBA (GUAR) GUM
One or more in vitro tests non-mammalian cells show positive mutation results		LINALOOL, AMMONIUM HYDROXIDE
One or more in vitro tests on mammalian cells show positive mutation results		UREA, TITANIUM DIOXIDE (NON-NANO), SODIUM BENZOATE, OLEIC ACID, METHYLPARABEN, GLYCERIN, GERANIOL, ETHANOLAMINE, EDTA, CETRIMONIUM CHLORIDE, ASCORBIC ACID (VITAMIN C), AMMONIUM CHLORIDE
Cancer - limited evidence		M-AMINOPHENOL, 6-HYDROXYINDOLE, 4-AMINO-2-HYDROXYTOLUENE, 2,4-DIAMINOPHENOXYETHANOL HCL
Mutagen - limited evidence		P-AMINOPHENOL
Cancer - not classifiable/not likely to be human carcinogen		RESORCINOL, P-PHENYLENEDIAMINE, ISOPROPYL ALCOHOL, HYDROGEN PEROXIDE, LIMONENE

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive effects at high doses		UREA, SODIUM BENZOATE, M-AMINOPHENOL, KAOLIN, ETHANOLAMINE, EDTA
One or more animal studies show reproductive effects at moderate doses		P-AMINOPHENOL
One or more animal studies show developmental effects at high doses		LIMONENE
One or more animal studies show reproductive effects at high doses		DIOCTYL SODIUM SULFOSUCCINATE
Limited evidence of developmental toxicity		ISOPROPYL ALCOHOL
One or more animal studies show reproductive effects at moderate doses		GLYCERIN
One or more animal studies show reproductive effects at low doses		SODIUM METASILICATE
Human nervous system toxicant - moderate evidence		P-PHENYLENEDIAMINE

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		SODIUM METASILICATE, SODIUM PERSULFATE, SODIUM SILICATE, SODIUM BENZOATE, POTASSIUM PERSULFATE, ETHANOLAMINE, CHLORHEXIDINE DIHYDROCHLORIDE, CETRIMONIUM CHLORIDE, RESORCINOL, CETEARETH-30, P-AMINOPHENOL, P-PHENYLENEDIAMINE, 4-AMINO-2-HYDROXYTOLUENE, 6-HYDROXYINDOLE, M-AMINOPHENOL, 2,4-DIAMINOPHENOXYETHANOL HCL
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel		SODIUM PERSULFATE, POTASSIUM PERSULFATE, P-AMINOPHENOL, P-PHENYLENEDIAMINE, M-AMINOPHENOL, 4-AMINO-2-HYDROXYTOLUENE, GERANIOL, CITRONELLOL, LINALOOL, LIMONENE
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		UREA, P-PHENYLENEDIAMINE, CHLORHEXIDINE DIHYDROCHLORIDE, CHLORHEXIDINE DIHYDROCHLORIDE, RESORCINOL
Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Safe for brief discontinuous use followed by thorough rinsing	products that are intended to be left on the skin	SODIUM PERSULFATE, POTASSIUM PERSULFATE, ETHANOLAMINE
Violation of government restrictions - Banned or found unsafe for use in cosmetics		METHYLPARABEN

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show brain and nervous system effects at high doses		GLYCERIN, 4-AMINO-2-HYDROXYTOLUENE
One or more animal studies show brain and nervous system effects at moderate doses		UREA, SODIUM BENZOATE, RESORCINOL, POLYQUATERNIUM-6, P-AMINOPHENOL, OLEIC ACID, ETHANOLAMINE, METHYLPARABEN, M-AMINOPHENOL, LINALOOL, KAOLIN, GERANIOL, EDTA, DIOCTYL SODIUM SULFOSUCCINATE, CITRONELLOL, CETEARETH-30
One or more animal studies show brain and nervous system effects at low doses		TETRASODIUM PYROPHOSPHATE
One or more animal studies show brain and nervous system effects at moderate doses		AMMONIUM CHLORIDE
Strong evidence of human neurotoxicity		ISOPROPYL ALCOHOL, P-PHENYLENEDIAMINE
Moderate evidence of human neurotoxicity		FRAGRANCE
One or more animal studies show brain and nervous system effects at very low doses		HYDROGEN PEROXIDE

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show endocrine system disruption at high doses		P-PHENYLENEDIAMINE, HYDROGEN PEROXIDE, GLYCERIN, CYAMOPSIS TETRAGONOLOBA (GUAR) GUM, AMMONIUM CHLORIDE, 4-AMINO-2-HYDROXYTOLUENE
Human any disruptor - strong evidence		RESORCINOL, METHYLPARABEN

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show immune effects at low doses		TITANIUM DIOXIDE (NON-NANO)
Human skin toxicant - strong evidence		METHYLPARABEN, POTASSIUM PERSULFATE, SODIUM METASILICATE, SODIUM PERSULFATE, SODIUM SILICATE
Limited evidence of immune system toxicity	products for use on skin	6-HYDROXYINDOLE
Human immune system toxicant - moderate evidence		CHLORHEXIDINE DIHYDROCHLORIDE
Human skin toxicant - strong evidence		M-AMINOPHENOL, ETHANOLAMINE
Known human immune system toxicant		FRAGRANCE
Human skin toxicant - strong evidence		CETRIMONIUM CHLORIDE, 4-AMINO-2-HYDROXYTOLUENE, 2-METHYLRESORCINOL
Possible human immune system toxicant		LINALOOL, CITRONELLOL
Known human immune system toxicant		RESORCINOL, P-PHENYLENEDIAMINE, P-AMINOPHENOL, GERANIOL, LIMONENE

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not suspected to be bioaccumulative		ISOPROPYL ALCOHOL, POLYQUATERNIUM-6, SODIUM SILICATE, TITANIUM DIOXIDE (NON-NANO)
Not suspected to be persistent		TRIDECETH-12
Not suspected to be bioaccumulative		AMMONIUM CHLORIDE, AMMONIUM HYDROXIDE, EDTA

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Classified as expected to be toxic or harmful		SODIUM SILICATE
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient)		MAGNESIUM STEARATE, POLYQUATERNIUM-6, TRIDECETH-12, VP/ VA COPOLYMER, LINALOOL, LIMONENE
One or more animal studies show liver effects at moderate doses (low dose studies may be unavailable for this ingredient)		CETEARETH-30
One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient)		CITRONELLOL, CYAMOPSIS TETRAGONOLOBA (GUAR) GUM
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		OLETH-30, SODIUM METASILICATE, OLEIC ACID, POTASSIUM PERSULFATE, UREA, 2-METHYLRESORCINOL, 4-AMINO-2-HYDROXYTOLUENE, CETRIMONIUM CHLORIDE
One or more animal studies show broad systemic effects at low doses		EDTA, GERANIOL, RESORCINOL, SODIUM BENZOATE, SODIUM PERSULFATE, TETRASODIUM PYROPHOSPHATE
Limited evidence of sense organ toxicity		ISOPROPYL ALCOHOL
One or more animal studies show kidney or renal system effects at very low doses		GLYCERIN
One or more animal studies show broad systemic effects at low doses		AMMONIUM HYDROXIDE, DIOCTYL SODIUM SULFOSUCCINATE
Possible human immune system toxicant		CHLORHEXIDINE DIHYDROCHLORIDE, ETHANOLAMINE, P-AMINOPHENOL
One or more animal studies show broad systemic effects at very low doses		AMMONIUM CHLORIDE, TITANIUM DIOXIDE (NON-NANO), HYDROGEN PEROXIDE
Known human any toxicant		METHYLPARABEN, P-PHENYLENEDIAMINE

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Occupational hazards related to handling		ISOPROPYL ALCOHOL, POTASSIUM PERSULFATE, SODIUM METASILICATE, HYDROGEN PEROXIDE, ETHANOLAMINE, LIMONENE, AMMONIUM HYDROXIDE
Ingredient not fully labeled - identity unknown		FRAGRANCE

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Suspected to be an environmental toxin		POLYQUATERNIUM-6, TRIDECETH-12
Not suspected to be an environmental toxin		SODIUM SILICATE, TITANIUM DIOXIDE (NON-NANO)
Suspected to be an environmental toxin		AMMONIUM CHLORIDE
Not suspected to be an environmental toxin		EDTA, ISOPROPYL ALCOHOL
Wildlife and environmental toxicity		RESORCINOL, P-PHENYLENEDIAMINE, P-AMINOPHENOL, M-AMINOPHENOL, LIMONENE, AMMONIUM HYDROXIDE, 6-HYDROXYINDOLE

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show skin irritation at high doses		SODIUM BENZOATE, 4-AMINO-2-HYDROXYTOLUENE
One or more animal studies show skin irritation at moderate doses		TRIDECETH-12, TITANIUM DIOXIDE (NON-NANO), P-AMINOPHENOL, M-AMINOPHENOL, GLYCERIN
One or more animal studies show skin irritation at low doses		OLETH-30, UREA, OLEIC ACID, METHYLPARABEN, DIOCTYL SODIUM SULFOSUCCINATE, DECETH-5, CETEARETH-30
One or more animal studies show skin irritation at very low doses		LINALOOL, GERANIOL, CITRONELLOL
Human skin irritant - moderate evidence		HYDROGEN PEROXIDE, ETHANOLAMINE, CHLORHEXIDINE DIHYDROCHLORIDE, AMMONIUM HYDROXIDE
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	SODIUM SILICATE
Classified as irritant		SODIUM METASILICATE
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	OLEYL ALCOHOL
Classified as irritant		POTASSIUM PERSULFATE, RESORCINOL, EDTA, ISOPROPYL ALCOHOL, P-PHENYLENEDIAMINE, 6-HYDROXYINDOLE, AMMONIUM CHLORIDE, LIMONENE

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Safety assessment was based on related chemical		OLETH-30, MAGNESIUM STEARATE, ASCORBIC ACID (VITAMIN C), CETYL ESTERS, OLETH-30, AMODIMETHICONE
Insufficient data to determine safety		M-AMINOPHENOL, P-AMINOPHENOL
Missing safety data noted by cosmetic industry review		P-AMINOPHENOL
Safety assessment was based on related chemical		SODIUM METASILICATE
Insufficient data to determine safety		P-PHENYLENEDIAMINE
Safety assessment was based on related chemical		PENTASODIUM PENTETATE
Missing safety data noted by cosmetic industry review		PENTASODIUM PENTETATE
Insufficient data to determine safety		4-AMINO-2-HYDROXYTOLUENE
Missing safety data noted by cosmetic industry review		P-PHENYLENEDIAMINE, M-AMINOPHENOL, 4-AMINO-2-HYDROXYTOLUENE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		UREA
Considered safe based on assumption of low absorption		SODIUM METASILICATE, SODIUM SILICATE, 4-AMINO-2-HYDROXYTOLUENE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		OLETH-30, SODIUM SILICATE, SODIUM METASILICATE, RESORCINOL, PENTASODIUM PENTETATE, P-PHENYLENEDIAMINE, P-AMINOPHENOL, OLEYL ALCOHOL, OLEIC ACID, METHYLPARABEN, MAGNESIUM STEARATE, M-AMINOPHENOL, EDTA, DIOCTYL SODIUM SULFOSUCCINATE, CETYL ESTERS, CETEARYL ALCOHOL, EUPHORBIA CERIFERA (CANDELILLA) WAX, ASCORBIC ACID (VITAMIN C), AMODIMETHICONE, 4-AMINO-2-HYDROXYTOLUENE
Not assessed for safety in cosmetics by industry panel		TRIDECETH-12
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		2-METHYLRESORCINOL
Not assessed for safety in cosmetics by industry panel		AMMONIUM THIOLACTATE, KYOUNIN YU, PRUNUS ARMENIACA (APRICOT) KERNEL OIL, PRUNUS ARMENIACA (APRICOT) OIL, SODIUM CARBOXYMETHYL STARCH, SODIUM STANNATE, TITANIUM DIOXIDE (NON-NANO), TRIDECETH-2 CARBOXAMIDE MEA, VP/ VA COPOLYMER, TETRASODIUM PYROPHOSPHATE, POLYQUATERNIUM-6, POLYDECENE, POLYQUATERNIUM-24, LINALOOL, MAGNESIUM PEROXIDE, ISOPROPYL ALCOHOL, LAURETH-12, HEXADIMETHRINE CHLORIDE, HYDROGEN PEROXIDE, GERANIOL, GLYCERIN, FRAGRANCE, LIMONENE, DECETH-5, DECETH-3, CYAMOPSIS TETRAGONOLOBA (GUAR) GUM, BEHENTRIMONIUM CHLORIDE, CITRONELLOL, AMMONIUM HYDROXIDE, AMMONIUM CHLORIDE, 6-HYDROXYINDOLE, ACRYLATES/ C10-30 ALKYL ACRYLATE CROSSPOLYMER, 2,4-DIAMINOPHENOXYETHANOL HCL

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to very low doses		P-PHENYLENEDIAMINE, POTASSIUM PERSULFATE, SODIUM PERSULFATE
Allowed workplace exposures restricted to low doses		TITANIUM DIOXIDE (NON-NANO), 6-HYDROXYINDOLE, AMMONIUM CHLORIDE, ETHANOLAMINE, HYDROGEN PEROXIDE, M-AMINOPHENOL, P-AMINOPHENOL, RESORCINOL
Allowed workplace exposures restricted to low doses		KAOLIN, SODIUM STANNATE
Allowed workplace exposures restricted to moderate doses		GLYCERIN, MAGNESIUM STEARATE, TETRASODIUM PYROPHOSPHATE
Allowed workplace exposures restricted to high doses		ISOPROPYL ALCOHOL

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood		TITANIUM DIOXIDE (NON-NANO)
One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood		P-AMINOPHENOL
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		DIOCTYL SODIUM SULFOSUCCINATE, GLYCERIN, HYDROGEN PEROXIDE, SODIUM BENZOATE
Interferes with gene expresion		METHYLPARABEN