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68% of breath fresheners have lower concerns
54% of tooth whitenings have lower concerns
59% of toothpastes have lower concerns




Compact for Safe Cosmetics
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Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes |
Ingredients from packaging: Active Ingredients: Sodium Fluoride (0.24%). Inactive Ingredients: Sodium Bicarbonate (Baking Soda), Water, Sorbitol, Glycerin, Hydrated Silica, Tetrasodium Pyrophosphate, Flavor, Sodium Lauroyl Sarcosinate, Sodium Lauryl Sulfate, Sodium Saccharin, Cellulose Gum, Blue 1, Yellow 5.
Directions from packaging: Do not swallow. Supervise children as necessary until capable of using without supervision. Adults and Children 2 Years and Older: Brush teeth thoroughly after meals or at least twice a day, or use as directed by a dentist or physician. Children Under 6 Years: Instruct in good brushing and rinsing habits (to minimize swallowing). Children Under 2 Years: Ask a dentist or physician.
Warnings from packaging: Keep out of reach of children under 6 years of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away.
| score | data gap | concerns | |
| SODIUM FLUORIDE (Active Ingredient) | 9 | 63% | Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Neurotoxicity, Endocrine disruption, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Occupational hazards, Biochemical or cellular level changes |
| FLAVOR | 4 | 100% | Miscellaneous |
| SODIUM LAUROYL SARCOSINATE | 4 | 73% | Violations, restrictions & warnings, Enhanced skin absorption, Contamination concerns (NITROSAMINES) |
| FD&C YELLOW 5 | 2 | 82% | Neurotoxicity, Organ system toxicity (non-reproductive) |
| SODIUM LAURYL SULFATE | 3 | 68% | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| FD&C BLUE 1 | 1 | 83% | none identified |
| TETRASODIUM PYROPHOSPHATE | 2 | 82% | Neurotoxicity, Organ system toxicity (non-reproductive), Occupational hazards |
| SODIUM BICARBONATE | 2 | 80% | none identified |
| SODIUM SACCHARIN | 2 | 80% | Neurotoxicity |
| HYDRATED SILICA | 2 | 79% | Persistence and bioaccumulation |
| GLYCERIN | 2 | 74% | Organ system toxicity (non-reproductive), Occupational hazards |
| SORBITOL | 1 | 88% | none identified |
| CELLULOSE GUM | 1 | 80% | none identified |
| WATER | 0 | 0% | innocuous |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show tumor formation at high doses | CELLULOSE GUM | |
| One or more in vitro tests on mammalian cells show positive mutation results | SORBITOL, SODIUM SACCHARIN, SODIUM LAURYL SULFATE | |
| One or more animal studies show tumor formation at low doses | SODIUM FLUORIDE | |
| One or more in vitro tests on mammalian cells show positive mutation results | FD&C YELLOW 5, GLYCERIN, SODIUM BICARBONATE | |
| Cancer - not classifiable/not likely to be human carcinogen | HYDRATED SILICA, FD&C BLUE 1 |
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show reproductive effects at high doses | SODIUM SACCHARIN, SODIUM LAURYL SULFATE, FD&C YELLOW 5 | |
| One or more animal studies show reproductive effects at moderate doses | SODIUM BICARBONATE, CELLULOSE GUM, GLYCERIN | |
| Human nervous system toxicant - moderate evidence | SODIUM FLUORIDE |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | SODIUM LAURYL SULFATE | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | SODIUM FLUORIDE | |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | SODIUM LAUROYL SARCOSINATE | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit) | SODIUM LAUROYL SARCOSINATE, SODIUM LAUROYL SARCOSINATE |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show brain and nervous system effects at high doses | SODIUM BICARBONATE, GLYCERIN | |
| One or more animal studies show brain and nervous system effects at low doses | TETRASODIUM PYROPHOSPHATE | |
| One or more animal studies show brain and nervous system effects at high doses | FD&C BLUE 1 | |
| One or more animal studies show brain and nervous system effects at moderate doses | SODIUM LAURYL SULFATE | |
| One or more animal studies show brain and nervous system effects at very low doses | FD&C YELLOW 5, SODIUM SACCHARIN | |
| Strong evidence of human neurotoxicity | SODIUM FLUORIDE |
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show endocrine system disruption at high doses | SODIUM LAURYL SULFATE, GLYCERIN | |
| One or more studies show endocrine system disruption at low doses | SODIUM FLUORIDE |
*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not suspected to be persistent | SODIUM LAURYL SULFATE | |
| Persistent, bioaccumulative in wildlife and humans | HYDRATED SILICA |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show gastrointestinal effects at high doses (low dose studies may be unavailable for this ingredient) | SORBITOL, SODIUM SACCHARIN, CELLULOSE GUM | |
| One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient) | FD&C BLUE 1 | |
| One or more animal studies show broad systemic effects at low doses | SODIUM LAURYL SULFATE, TETRASODIUM PYROPHOSPHATE | |
| One or more animal studies show cardiovascular effects at moderate doses (low dose studies may be unavailable for this ingredient) | SODIUM BICARBONATE | |
| One or more animal studies show musculoskeletal effects at very low doses | FD&C YELLOW 5, GLYCERIN, SODIUM FLUORIDE |
*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Occupational hazards related to handling | SODIUM FLUORIDE | |
| Ingredient not fully labeled - identity unknown | FLAVOR |
*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Designated as safe for general or specific, limited use in food | TETRASODIUM PYROPHOSPHATE, SORBITOL, SODIUM SACCHARIN, SODIUM LAURYL SULFATE, SODIUM FLUORIDE, GLYCERIN, SODIUM BICARBONATE, FD&C YELLOW 5, FD&C BLUE 1, CELLULOSE GUM | |
| Used in food or as an additive with limited or no toxicity information available | SODIUM FLUORIDE |
*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Suspected to be an environmental toxin | SODIUM LAURYL SULFATE |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show skin irritation at moderate doses | SODIUM BICARBONATE, GLYCERIN | |
| One or more animal studies show skin irritation at very low doses | SODIUM LAURYL SULFATE |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | SODIUM BICARBONATE, CELLULOSE GUM | |
| Not assessed for safety in cosmetics by industry panel | HYDRATED SILICA, FLAVOR, TETRASODIUM PYROPHOSPHATE, SORBITOL, SODIUM SACCHARIN, GLYCERIN |
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to very low doses | SODIUM FLUORIDE | |
| Allowed workplace exposures restricted to moderate doses | GLYCERIN, TETRASODIUM PYROPHOSPHATE |
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood | SODIUM FLUORIDE | |
| One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood | SODIUM LAURYL SULFATE | |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | CELLULOSE GUM, GLYCERIN, SODIUM BICARBONATE |
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