Ion Color Brilliance Permanent Creme Hair Color (red 7rr) (2007 formulation) || Skin Deep: Cosmetic Safety Reviews

ION COLOR BRILLIANCE PERMANENT CREME HAIR COLOR (RED 7RR) (2007 FORMULATION)

last updated: 12/01/07 brand: Ion Color Brilliance by Ion Professional Products, Inc.

SCORE

moderate hazard (out of 10)

77%

data gap

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11% of hair color and bleachings have lower concerns

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company's animal testing policy is unknown.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards

Note: This product formulation was obtained from the FDA VCRD.

Ingredients from packaging: WATER, AMMONIA, MYRISTYL ALCOHOL, FRAGRANCE, COCAMIDOPROPYL BETAINE, DIMETHICONE PEG-8 MEADOWFOAMATE, BISAMINO PEG/PPG-41/3 AMINOETHYL PG-PROPYL DIMETHICONE, SODIUM SULFITE, POLYQUATERNIUM-22, EDTA, ERYTHORBIC ACID, STEARYL ALCOHOL, SIMETHICONE, GLYCERIN, TRITICUM VULGARE (WHEAT) GERM PROTEIN, 5-AMINO-6-CHLORO-O-CRESOL, P-AMINOPHENOL, 4-AMINO-2-HYDROXYTOLUENE, 2-AMINO-6-CHLORO-4-NITROPHENOL, BASIC RED 2, PROPYLENE GLYCOL, CETYL ALCOHOL, CETEARYL ALCOHOL, ETHOXYDIGLYCOL, PEG-40 HYDROGENATED CASTOR OIL, CETEARETH-50, LAURYL ALCOHOL

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ingredients

	score	data gap	concerns
P-AMINOPHENOL	8	57%	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards
FRAGRANCE	8	100%	Neurotoxicity, Allergies/immunotoxicity, Miscellaneous
CETEARETH-50	5	71%	Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
BISAMINO PEG/ PPG-41/ 3 AMINOETHYL PG-PROPYL DIMETHICONE	4	76%	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
DIMETHICONE PEG-8 MEADOWFOAMATE	4	76%	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
PEG-40 HYDROGENATED CASTOR OIL	4	75%	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
5-AMINO-6-CHLORO-O-CRESOL	5	73%	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity
2-AMINO-6-CHLORO-4-NITROPHENOL	5	71%	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity
4-AMINO-2-HYDROXYTOLUENE	5	67%	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity
COCAMIDOPROPYL BETAINE	5	63%	Allergies/immunotoxicity, Contamination concerns (NITROSAMINES)
PROPYLENE GLYCOL	4	60%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
SODIUM SULFITE	3	87%	Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
AMMONIA	3	79%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
EDTA	3	78%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
BASIC RED 2	2	72%	Cancer, Neurotoxicity
ETHOXYDIGLYCOL	2	82%	Organ system toxicity (non-reproductive)
GLYCERIN	2	74%	Organ system toxicity (non-reproductive), Occupational hazards
CETEARYL ALCOHOL	0	93%	none identified
CETYL ALCOHOL	1	87%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
ERYTHORBIC ACID	1	87%	none identified
1-DODECANOL LAURYL ALCOHOL	1	84%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
MYRISTYL ALCOHOL	1	84%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
STEARYL ALCOHOL	1	84%	Irritation (skin, eyes, or lungs)
POLYQUATERNIUM-22	0	100%	none identified
SIMETHICONE	0	100%	none identified
WHEAT GERM PROTEIN	0	100%	none identified
WATER	0	0%	innocuous

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show tumor formation at high doses		STEARYL ALCOHOL, MYRISTYL ALCOHOL, 1-DODECANOL
One or more in vitro tests non-mammalian cells show positive mutation results		ETHOXYDIGLYCOL
One or more in vitro tests on mammalian cells show positive mutation results		SODIUM SULFITE, PROPYLENE GLYCOL, GLYCERIN, ERYTHORBIC ACID, EDTA, AMMONIA
Cancer - limited evidence		BASIC RED 2, 5-AMINO-6-CHLORO-O-CRESOL, 4-AMINO-2-HYDROXYTOLUENE, 2-AMINO-6-CHLORO-4-NITROPHENOL
Mutagen - limited evidence		P-AMINOPHENOL

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive effects at high doses		ETHOXYDIGLYCOL, EDTA
One or more animal studies show reproductive effects at moderate doses		P-AMINOPHENOL, PROPYLENE GLYCOL, GLYCERIN

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		PEG-40 HYDROGENATED CASTOR OIL, PROPYLENE GLYCOL, CETEARETH-50, DIMETHICONE PEG-8 MEADOWFOAMATE, COCAMIDOPROPYL BETAINE, BISAMINO PEG/ PPG-41/ 3 AMINOETHYL PG-PROPYL DIMETHICONE, 2-AMINO-6-CHLORO-4-NITROPHENOL, BASIC RED 2, 5-AMINO-6-CHLORO-O-CRESOL, 2-AMINO-6-CHLORO-4-NITROPHENOL, 4-AMINO-2-HYDROXYTOLUENE
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel		4-AMINO-2-HYDROXYTOLUENE, 5-AMINO-6-CHLORO-O-CRESOL
Determined safe for use in cosmetics, subject to concentration or use limitations - any		P-AMINOPHENOL
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel		P-AMINOPHENOL, 2-AMINO-6-CHLORO-4-NITROPHENOL

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show brain and nervous system effects at high doses		PROPYLENE GLYCOL, GLYCERIN, ETHOXYDIGLYCOL, 4-AMINO-2-HYDROXYTOLUENE
One or more animal studies show brain and nervous system effects at moderate doses		CETEARETH-50, P-AMINOPHENOL, EDTA
One or more animal studies show brain and nervous system effects at low doses		SODIUM SULFITE
One or more animal studies show brain and nervous system effects at very low doses		BASIC RED 2
Moderate evidence of human neurotoxicity		FRAGRANCE

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show endocrine system disruption at high doses		GLYCERIN, 4-AMINO-2-HYDROXYTOLUENE

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Human immune system toxicant - moderate evidence		SODIUM SULFITE
Limited evidence of skin and immune system toxicity		PROPYLENE GLYCOL
Human skin toxicant - strong evidence		5-AMINO-6-CHLORO-O-CRESOL, 2-AMINO-6-CHLORO-4-NITROPHENOL, 4-AMINO-2-HYDROXYTOLUENE
Known human immune system toxicant		P-AMINOPHENOL, FRAGRANCE, COCAMIDOPROPYL BETAINE

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not suspected to be bioaccumulative		EDTA, AMMONIA
Not suspected to be persistent		MYRISTYL ALCOHOL, CETYL ALCOHOL, 1-DODECANOL

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Classified as expected to be toxic or harmful		MYRISTYL ALCOHOL
One or more animal studies show metabolic effects at high doses (low dose studies may be unavailable for this ingredient)		PROPYLENE GLYCOL, 2-AMINO-6-CHLORO-4-NITROPHENOL, CETYL ALCOHOL, STEARYL ALCOHOL, ERYTHORBIC ACID
One or more animal studies show liver effects at moderate doses (low dose studies may be unavailable for this ingredient)		CETEARETH-50, BASIC RED 2, 4-AMINO-2-HYDROXYTOLUENE, 1-DODECANOL
Limited evidence of sense organ toxicity		PEG-40 HYDROGENATED CASTOR OIL, BISAMINO PEG/ PPG-41/ 3 AMINOETHYL PG-PROPYL DIMETHICONE, DIMETHICONE PEG-8 MEADOWFOAMATE, ETHOXYDIGLYCOL
One or more animal studies show broad systemic effects at low doses		EDTA
Possible human immune system toxicant		SODIUM SULFITE
One or more animal studies show kidney or renal system effects at very low doses		GLYCERIN
Possible human immune system toxicant		P-AMINOPHENOL
Known human sense organ toxicant		AMMONIA

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Ingredient not fully labeled - identity unknown		FRAGRANCE
Occupational hazards related to handling		AMMONIA

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Suspected to be an environmental toxin		MYRISTYL ALCOHOL
Not suspected to be an environmental toxin		EDTA
Suspected to be an environmental toxin		CETYL ALCOHOL, 1-DODECANOL
Wildlife and environmental toxicity		P-AMINOPHENOL, AMMONIA

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show skin irritation at high doses		SODIUM SULFITE, 4-AMINO-2-HYDROXYTOLUENE
One or more animal studies show skin irritation at moderate doses		P-AMINOPHENOL, GLYCERIN, ETHOXYDIGLYCOL
One or more animal studies show skin irritation at low doses		CETEARETH-50, MYRISTYL ALCOHOL
One or more animal studies show skin irritation at very low doses		1-DODECANOL, CETYL ALCOHOL
Human skin irritant - moderate evidence		AMMONIA
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	STEARYL ALCOHOL
Classified as skin irritant		PROPYLENE GLYCOL, EDTA

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Insufficient data to determine safety		5-AMINO-6-CHLORO-O-CRESOL
Missing safety data noted by cosmetic industry review		P-AMINOPHENOL
Safety assessment was based on related chemical		PROPYLENE GLYCOL
Insufficient data to determine safety		4-AMINO-2-HYDROXYTOLUENE, P-AMINOPHENOL, 2-AMINO-6-CHLORO-4-NITROPHENOL
Missing safety data noted by cosmetic industry review		5-AMINO-6-CHLORO-O-CRESOL
Considered safe based on assumption of low absorption		4-AMINO-2-HYDROXYTOLUENE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		STEARYL ALCOHOL
Missing safety data noted by cosmetic industry review		5-AMINO-6-CHLORO-O-CRESOL, 2-AMINO-6-CHLORO-4-NITROPHENOL, 4-AMINO-2-HYDROXYTOLUENE
Considered safe based on assumption of low absorption		5-AMINO-6-CHLORO-O-CRESOL
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		5-AMINO-6-CHLORO-O-CRESOL, ERYTHORBIC ACID, ETHOXYDIGLYCOL, P-AMINOPHENOL
Considered safe based on assumption of low absorption		2-AMINO-6-CHLORO-4-NITROPHENOL
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		MYRISTYL ALCOHOL, EDTA, SODIUM SULFITE, CETEARYL ALCOHOL, CETYL ALCOHOL, 4-AMINO-2-HYDROXYTOLUENE
Not assessed for safety in cosmetics by industry panel		BASIC RED 2, WHEAT GERM PROTEIN, SIMETHICONE, POLYQUATERNIUM-22, GLYCERIN, BISAMINO PEG/ PPG-41/ 3 AMINOETHYL PG-PROPYL DIMETHICONE, DIMETHICONE PEG-8 MEADOWFOAMATE, FRAGRANCE, AMMONIA, 1-DODECANOL

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to moderate doses		GLYCERIN
Allowed workplace exposures restricted to low doses		P-AMINOPHENOL, AMMONIA

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood		P-AMINOPHENOL
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		GLYCERIN, PROPYLENE GLYCOL