Ion Color Brilliance Permanent Creme Hair Color (ash 10a Blonde) (2007 formulation) || Skin Deep: Cosmetic Safety Reviews

ION COLOR BRILLIANCE PERMANENT CREME HAIR COLOR (ASH 10A BLONDE) (2007 FORMULATION)

last updated: 12/01/07 brand: Ion Color Brilliance by Ion Professional Products, Inc.

SCORE

high hazard (out of 10)

77%

data gap

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24% of hair color and bleachings have lower concerns

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company's animal testing policy is unknown.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Organ system toxicity (non-reproductive), Miscellaneous, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards

Note: This product formulation was obtained from the FDA VCRD.

Ingredients from packaging: WATER, AMMONIA, MYRISTYL ALCOHOL, FRAGRANCE, COCAMIDOPROPYL BETAINE, DIMETHICONE PEG-8 MEADOWFOAMATE, BISAMINO PEG/PPG-41/3 AMINOETHYL PG-PROPYL DIMETHICONE, SODIUM SULFITE, POLYQUATERNIUM-22, EDTA, ERYTHORBIC ACID, STEARYL ALCOHOL, SIMETHICONE, GLYCERIN, TRITICUM VULGARE (WHEAT) GERM PROTEIN, P-PHENYLENEDIAMINE, 2-METHYLRESORCINOL, 2,4-DIAMINOPHENOXYETHANOL HYDROCHLORIDE, P-AMINOPHENOL, PROPYLENE GLYCOL, CETYL ALCOHOL, CETEARYL ALCOHOL, ETHOXYDIGLYCOL, PEG-40 HYDROGENATED CASTOR OIL, CETEARETH-50, LAURYL ALCOHOL

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ingredients

	score	data gap	concerns
P-PHENYLENEDIAMINE	10	52%	Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
P-AMINOPHENOL	8	57%	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards
FRAGRANCE	8	100%	Neurotoxicity, Allergies/immunotoxicity, Miscellaneous
CETEARETH-50	5	71%	Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
BISAMINO PEG/ PPG-41/ 3 AMINOETHYL PG-PROPYL DIMETHICONE	4	76%	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
DIMETHICONE PEG-8 MEADOWFOAMATE	4	76%	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
PEG-40 HYDROGENATED CASTOR OIL	4	75%	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
COCAMIDOPROPYL BETAINE	5	63%	Allergies/immunotoxicity, Contamination concerns (NITROSAMINES)
PROPYLENE GLYCOL	4	60%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
SODIUM SULFITE	3	87%	Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
AMMONIA	3	79%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
EDTA	3	78%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
2-METHYLRESORCINOL	2	84%	Allergies/immunotoxicity
ETHOXYDIGLYCOL	2	82%	Organ system toxicity (non-reproductive)
GLYCERIN	2	74%	Organ system toxicity (non-reproductive), Occupational hazards
CETEARYL ALCOHOL	0	93%	none identified
CETYL ALCOHOL	1	87%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
ERYTHORBIC ACID	1	87%	none identified
1-DODECANOL LAURYL ALCOHOL	1	84%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
MYRISTYL ALCOHOL	1	84%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
STEARYL ALCOHOL	1	83%	Irritation (skin, eyes, or lungs)
2,4-DIAMINOPHENOXYETHANOL HCL 2,4-DIAMINOPHENOXYETHANOL HYDROCHLORIDE	1	75%	Cancer
POLYQUATERNIUM-22	0	100%	none identified
SIMETHICONE	0	100%	none identified
WHEAT GERM PROTEIN	0	100%	none identified
WATER	0	0%	innocuous

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show tumor formation at high doses		MYRISTYL ALCOHOL, STEARYL ALCOHOL, 1-DODECANOL
One or more in vitro tests non-mammalian cells show positive mutation results		ETHOXYDIGLYCOL, ERYTHORBIC ACID, 2,4-DIAMINOPHENOXYETHANOL HCL
One or more in vitro tests on mammalian cells show positive mutation results		SODIUM SULFITE, PROPYLENE GLYCOL, P-PHENYLENEDIAMINE, P-AMINOPHENOL, GLYCERIN, EDTA, AMMONIA

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive effects at high doses		GLYCERIN, ETHOXYDIGLYCOL, EDTA, P-AMINOPHENOL
One or more animal studies show reproductive effects at moderate doses		PROPYLENE GLYCOL
Human nervous system toxicant - moderate evidence		P-PHENYLENEDIAMINE

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		CETEARETH-50, PEG-40 HYDROGENATED CASTOR OIL, PROPYLENE GLYCOL, DIMETHICONE PEG-8 MEADOWFOAMATE, COCAMIDOPROPYL BETAINE, 2,4-DIAMINOPHENOXYETHANOL HCL, P-AMINOPHENOL, P-PHENYLENEDIAMINE, BISAMINO PEG/ PPG-41/ 3 AMINOETHYL PG-PROPYL DIMETHICONE
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel		P-PHENYLENEDIAMINE, P-AMINOPHENOL
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		P-PHENYLENEDIAMINE

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show brain and nervous system effects at high doses		PROPYLENE GLYCOL, P-PHENYLENEDIAMINE, GLYCERIN
Moderate evidence of human neurotoxicity		FRAGRANCE
One or more animal studies show brain and nervous system effects at moderate doses		CETEARETH-50
One or more animal studies show brain and nervous system effects at high doses		ETHOXYDIGLYCOL
One or more animal studies show brain and nervous system effects at moderate doses		P-AMINOPHENOL
One or more animal studies show brain and nervous system effects at low doses		SODIUM SULFITE
One or more animal studies show brain and nervous system effects at moderate doses		EDTA

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show endocrine system disruption at high doses		P-PHENYLENEDIAMINE, GLYCERIN

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Limited evidence of immune system toxicity		SODIUM SULFITE
Limited evidence of skin and immune system toxicity		PROPYLENE GLYCOL, P-PHENYLENEDIAMINE
Human skin toxicant - strong evidence		P-AMINOPHENOL, 2-METHYLRESORCINOL
Known human immune system toxicant		FRAGRANCE, COCAMIDOPROPYL BETAINE

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show metabolic effects at high doses (low dose studies may be unavailable for this ingredient)		P-PHENYLENEDIAMINE, 2-METHYLRESORCINOL, P-AMINOPHENOL, GLYCERIN, ETHOXYDIGLYCOL, PROPYLENE GLYCOL, CETYL ALCOHOL, STEARYL ALCOHOL, PEG-40 HYDROGENATED CASTOR OIL, ERYTHORBIC ACID
One or more animal studies show liver effects at moderate doses (low dose studies may be unavailable for this ingredient)		CETEARETH-50
One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient)		1-DODECANOL
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		EDTA, SODIUM SULFITE
Limited evidence of sense organ toxicity		DIMETHICONE PEG-8 MEADOWFOAMATE, BISAMINO PEG/ PPG-41/ 3 AMINOETHYL PG-PROPYL DIMETHICONE
Known human sense organ toxicant		AMMONIA

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Occupational hazards related to handling		AMMONIA
Ingredient not fully labeled - identity unknown		FRAGRANCE

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Wildlife and environmental toxicity		P-PHENYLENEDIAMINE, P-AMINOPHENOL, AMMONIA

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show skin irritation at moderate doses		P-AMINOPHENOL
One or more animal studies show skin irritation at high doses		SODIUM SULFITE
One or more animal studies show skin irritation at moderate doses		STEARYL ALCOHOL, PROPYLENE GLYCOL, GLYCERIN, ETHOXYDIGLYCOL, CETYL ALCOHOL
One or more animal studies show skin irritation at low doses		CETEARETH-50, P-PHENYLENEDIAMINE, MYRISTYL ALCOHOL
One or more animal studies show skin irritation at very low doses		1-DODECANOL
Human skin irritant - moderate evidence		AMMONIA
Classified as irritant		EDTA

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Safety assessment was based on related chemical		PROPYLENE GLYCOL
Insufficient data to determine safety		P-AMINOPHENOL, P-PHENYLENEDIAMINE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		STEARYL ALCOHOL
Missing safety data noted by cosmetic industry review		P-AMINOPHENOL, P-PHENYLENEDIAMINE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		P-PHENYLENEDIAMINE, P-AMINOPHENOL, SODIUM SULFITE, MYRISTYL ALCOHOL, ERYTHORBIC ACID, ETHOXYDIGLYCOL, EDTA, CETYL ALCOHOL, CETEARYL ALCOHOL, 2-METHYLRESORCINOL
Not assessed for safety in cosmetics by industry panel		WHEAT GERM PROTEIN, SIMETHICONE, POLYQUATERNIUM-22, GLYCERIN, FRAGRANCE, DIMETHICONE PEG-8 MEADOWFOAMATE, BISAMINO PEG/ PPG-41/ 3 AMINOETHYL PG-PROPYL DIMETHICONE, AMMONIA, 2,4-DIAMINOPHENOXYETHANOL HCL, 1-DODECANOL

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to moderate doses		GLYCERIN
Allowed workplace exposures restricted to high doses		AMMONIA
Allowed workplace exposures restricted to low doses		P-AMINOPHENOL
Allowed workplace exposures restricted to very low doses		P-PHENYLENEDIAMINE

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		PROPYLENE GLYCOL, GLYCERIN, P-AMINOPHENOL