

Compact for Safe Cosmetics
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Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns, Occupational hazards, Biochemical or cellular level changes |
Ingredients from packaging: Butyl Acetate, Toluene, Nitrocellulose, Ethyl Acetate, Toluene Sulfonamide/Formaldehyde Resin, Dibutyl Phthalate, Isopropyl Alcohol, Stearalkonium Hectorite, Benzophenone-1, Camellia Oleifera Extract, Biotin, [+/-] (May Contain) Mica, Bismuth Oxychloride, Titanium Dioxide, Red Iron Oxide, Black Iron Oxide, Ferric Ammonium Ferrocyanide, FD&C Yellow 5 Aluminum Lake, D&C Red 6 Barium Lake, D&C Red 7 Calcium Lake, D&C Red 34 Calcium Lake, Polyethylene Teraphthalate
Directions from packaging: Shake well before use.
Warnings from packaging: Warnings:Avoid heat or flame.
| score | data gap | concerns | |
| TOLUENE | 10 | 54% | Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Neurotoxicity, Allergies/immunotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (BENZENE), Occupational hazards |
| DIBUTYL PHTHALATE | 10 | 49% | Developmental/reproductive toxicity, Violations, restrictions & warnings, Neurotoxicity, Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Occupational hazards |
| FERRIC AMMONIUM FERROCYANIDE | 5 | 75% | Developmental/reproductive toxicity, Neurotoxicity, Endocrine disruption, Organ system toxicity (non-reproductive), Occupational hazards |
| BENZOPHENONE-1 | 5 | 79% | Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive) |
| ETHYL ACETATE | 4 | 78% | Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| FD&C YELLOW 5 ALUMINUM LAKE | 4 | 91% | Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive) |
| D&C RED 6 BARIUM LAKE | 4 | 90% | Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive) |
| TITANIUM DIOXIDE (NON-NANO) | 1 | 81% | Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards, Biochemical or cellular level changes |
| D&C RED 34 CALCIUM LAKE | 0 | 75% | none identified |
| D&C RED 7 LAKE D&C RED 7 CALCIUM LAKE | 4 | 73% | Developmental/reproductive toxicity, Neurotoxicity |
| ISOPROPYL ALCOHOL | 4 | 72% | Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| TOSYLAMIDE/ FORMALDEHYDE RESIN TOLUENE SULFONAMIDE/FORMALDEHYDE RESIN | 4 | 72% | Allergies/immunotoxicity |
| MICA | 3 | 75% | Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Occupational hazards |
| IRON OXIDES RED IRON OXIDE | 2 | 85% | Persistence and bioaccumulation, Enhanced skin absorption |
| BIOTIN | 2 | 82% | Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive) |
| D&C RED 7 ZIRCONIUM LAKE D&C RED 7 CALCIUM LAKE | 2 | 76% | Violations, restrictions & warnings |
| NITROCELLULOSE | 1 | 94% | Organ system toxicity (non-reproductive) |
| POLYETHYLENE TEREPHTHALATE POLYETHYLENE TERAPHTHALATE | 1 | 93% | Organ system toxicity (non-reproductive) |
| STEARALKONIUM HECTORITE | 1 | 93% | Contamination concerns (NITROSAMINES, FREE AMINES) |
| BISMUTH OXYCHLORIDE | 1 | 89% | none identified |
| BUTYL ACETATE | 1 | 78% | Irritation (skin, eyes, or lungs), Occupational hazards |
| CAMELLIA OLEIFERA (TEA-OIL CAMELLIA) LEAF EXTRACT CAMELLIA OLEIFERA EXTRACT | 0 | 100% | none identified |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show tumor formation at moderate doses | POLYETHYLENE TEREPHTHALATE | |
| One or more in vitro tests on mammalian cells show positive mutation results | TITANIUM DIOXIDE (NON-NANO), ETHYL ACETATE | |
| Cancer - not classifiable/not likely to be human carcinogen | TOLUENE | |
| Cancer - not classifiable/not likely to be human carcinogen | DIBUTYL PHTHALATE | |
| Cancer - not classifiable/not likely to be human carcinogen | ISOPROPYL ALCOHOL |
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Human nervous system toxicant - moderate evidence | FD&C YELLOW 5 ALUMINUM LAKE, FERRIC AMMONIUM FERROCYANIDE | |
| One or more animal studies show reproductive effects at low doses | BIOTIN | |
| Limited evidence of developmental toxicity | ISOPROPYL ALCOHOL | |
| Human nervous system toxicant - moderate evidence | ETHYL ACETATE, D&C RED 7 LAKE, D&C RED 6 BARIUM LAKE | |
| Possible human developmental toxicant | DIBUTYL PHTHALATE, TOLUENE |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Determined safe for use in cosmetics, subject to concentration or use limitations - any | D&C RED 7 LAKE, TOLUENE | |
| Violation of government restrictions - Banned or found unsafe for use in cosmetics | DIBUTYL PHTHALATE | |
| Violation of industry recommendations - Unsafe for use in cosmetics | TOLUENE | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Restricted in EU cosmetics (mandatory manufacturing or structural specifications) | D&C RED 7 ZIRCONIUM LAKE |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study | BUTYL ACETATE | |
| One or more animal studies show brain and nervous system effects at high doses | BENZOPHENONE-1 | |
| One or more animal studies show brain and nervous system effects at low doses | BIOTIN | |
| Strong evidence of human neurotoxicity | TOLUENE, FERRIC AMMONIUM FERROCYANIDE, FD&C YELLOW 5 ALUMINUM LAKE, ETHYL ACETATE, D&C RED 7 LAKE, DIBUTYL PHTHALATE, D&C RED 6 BARIUM LAKE, ISOPROPYL ALCOHOL |
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Human any disruptor - strong evidence | DIBUTYL PHTHALATE | |
| Limited evidence of endocrine disruption | FERRIC AMMONIUM FERROCYANIDE | |
| Human any disruptor - strong evidence | BENZOPHENONE-1 |
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Human skin toxicant - strong evidence | BENZOPHENONE-1 | |
| One or more animal studies show gastrointestinal effects at moderate doses | MICA | |
| One or more animal studies show immune effects at low doses | TITANIUM DIOXIDE (NON-NANO) | |
| Limited evidence of immune system toxicity | TOLUENE | |
| Known human immune system toxicant | TOSYLAMIDE/ FORMALDEHYDE RESIN, DIBUTYL PHTHALATE |
*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not suspected to be bioaccumulative | TOLUENE, TITANIUM DIOXIDE (NON-NANO), POLYETHYLENE TEREPHTHALATE, ISOPROPYL ALCOHOL | |
| Persistent, bioaccumulative in wildlife | DIBUTYL PHTHALATE | |
| Persistent, bioaccumulative in wildlife and humans | MICA, IRON OXIDES |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Classified as expected to be toxic or harmful | POLYETHYLENE TEREPHTHALATE, NITROCELLULOSE | |
| One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient) | BISMUTH OXYCHLORIDE | |
| Limited evidence of sense organ toxicity | ETHYL ACETATE, ISOPROPYL ALCOHOL, D&C RED 6 BARIUM LAKE, FERRIC AMMONIUM FERROCYANIDE | |
| One or more animal studies show broad systemic effects at low doses | BENZOPHENONE-1 | |
| Limited evidence of any toxicity | FD&C YELLOW 5 ALUMINUM LAKE | |
| One or more animal studies show cardiovascular effects at very low doses | TITANIUM DIOXIDE (NON-NANO) | |
| One or more animal studies show blood effects at low doses | BIOTIN | |
| Possible human respiratory toxicant | MICA | |
| Known human respiratory toxicant | DIBUTYL PHTHALATE, TOLUENE |
*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not suspected to be an environmental toxin | TITANIUM DIOXIDE (NON-NANO), POLYETHYLENE TEREPHTHALATE, ISOPROPYL ALCOHOL, NITROCELLULOSE | |
| Wildlife and environmental toxicity | TOLUENE, DIBUTYL PHTHALATE |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show skin irritation at moderate doses | TITANIUM DIOXIDE (NON-NANO) | |
| Classified as skin irritant | products for use on skin | TOLUENE, BUTYL ACETATE |
| Classified as irritant | ISOPROPYL ALCOHOL, ETHYL ACETATE |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Insufficient data to determine safety | TOLUENE | |
| Considered safe based on assumption of low absorption | TOLUENE | |
| Insufficient data to determine safety | DIBUTYL PHTHALATE | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | TOLUENE, STEARALKONIUM HECTORITE, ETHYL ACETATE, DIBUTYL PHTHALATE, BUTYL ACETATE, BIOTIN | |
| Not assessed for safety in cosmetics by industry panel | ISOPROPYL ALCOHOL, NITROCELLULOSE, POLYETHYLENE TEREPHTHALATE, TITANIUM DIOXIDE (NON-NANO) | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | BENZOPHENONE-1 | |
| Not assessed for safety in cosmetics by industry panel | FERRIC AMMONIUM FERROCYANIDE, CAMELLIA OLEIFERA (TEA-OIL CAMELLIA) LEAF EXTRACT |
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to high doses | TOLUENE, ISOPROPYL ALCOHOL, ETHYL ACETATE, BUTYL ACETATE | |
| Allowed workplace exposures restricted to moderate doses | DIBUTYL PHTHALATE | |
| Allowed workplace exposures restricted to low doses | MICA, FERRIC AMMONIUM FERROCYANIDE, | |
| Allowed workplace exposures restricted to low doses | TITANIUM DIOXIDE (NON-NANO) |
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | DIBUTYL PHTHALATE | |
| One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood | TITANIUM DIOXIDE (NON-NANO) |
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