OPI AVOPLEX EXFOLIATING CUTICLE TREATMENT (2007 FORMULATION)
last updated: 12/01/07 brand: OPI by OPI Products
COMPANY POLICIES
Compact for Safe Cosmetics
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Animal Testing Policy |
Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
 | Cancer |
| Developmental/reproductive toxicity |
| Violations, restrictions & warnings |
| Allergies/immunotoxicity |
| Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes |
Ingredients from packaging: WATER, SALICYLIC ACID, SALIX ALBA (WILLOW) BARK EXTRACT, PPG-1 TRIDECETH-6, ISOBUTYLPARABEN, BUTYLPARABEN, TOCOPHEROL, BUTYLPHENYL METHYLPROPIONAL, PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES, ETHYLHEXYL PALMITATE, LECITHIN, POLYQUATERNIUM-37, HYDROXYCITRONELLAL, CAPRYLIC/CAPRIC TRIGLYCERIDE, ALCOHOL, ASCORBYL PALMITATE, GLYCERYL STEARATE, OLEIC ACID, METHYLPARABEN, CAMELLIA SINENSIS LEAF EXTRACT, CITRUS AURANTIUM DULCIS (ORANGE) FRUIT EXTRACT, ISOPROPYL PALMITATE, CITRUS MEDICA LIMONUM (LEMON) FRUIT EXTRACT, PYRUS MALUS (APPLE) FRUIT EXTRACT, SACCHARUM OFFICINARUM (SUGAR CANE) EXTRACT, PROPYLENE GLYCOL, BIS-PEG-18 METHYL ETHER DIMETHYL SILANE, PROPYLENE GLYCOL DICAPRYLATE/DICAPRATE, FRAGRANCE, ISOPROPYLPARABEN
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ingredients
| score | data gap | concerns | |
| METHYLPARABEN | 10 | 63% | Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes |
| FRAGRANCE | 8 | 100% | Neurotoxicity, Allergies/immunotoxicity, Miscellaneous |
| SALICYLIC ACID | 7 | 66% | Violations, restrictions & warnings, Neurotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Enhanced skin absorption |
| BUTYLPARABEN | 6 | 79% | Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Biochemical or cellular level changes |
| BIS-PEG-18 METHYL ETHER DIMETHYL SILANE | 4 | 76% | Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE) |
| LECITHIN | 3 | 70% | Multiple, additive exposure sources, Enhanced skin absorption, Contamination concerns (NITROSAMINES) |
| LILIAL BUTYLPHENYL METHYLPROPIONAL | 5 | 64% | Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs) |
| HYDROXYCITRONELLAL | 5 | 62% | Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs) |
| ETHANOL ALCOHOL | 5 | 74% | Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards |
| PROPYLENE GLYCOL | 4 | 60% | Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption |
| ISOPROPYLPARABEN | 3 | 84% | Allergies/immunotoxicity, Organ system toxicity (non-reproductive) |
| ISOBUTYLPARABEN | 3 | 83% | Allergies/immunotoxicity, Organ system toxicity (non-reproductive) |
| TOCOPHEROL | 2 | 87% | Contamination concerns (HYDROQUINONE) |
| OLEIC ACID | 1 | 82% | Irritation (skin, eyes, or lungs) |
| CAMELLIA SINENSIS (GREEN TEA) LEAF EXTRACT CAMELLIA SINENSIS LEAF EXTRACT | 2 | 76% | Violations, restrictions & warnings |
| CAPRYLIC/ CAPRIC TRIGLYCERIDE | 0 | 94% | none identified |
| CITRUS AURANTIUM DULCIS (ORANGE) FRUIT EXTRACT | 1 | 94% | Multiple, additive exposure sources |
| POLYQUATERNIUM-37 | 0 | 94% | none identified |
| SALIX ALBA (WHITE WILLOW) BARK EXTRACT SALIX ALBA (WILLOW) BARK EXTRACT | 1 | 93% | Organ system toxicity (non-reproductive) |
| ETHYLHEXYL PALMITATE | 1 | 92% | Irritation (skin, eyes, or lungs) |
| PROPYLENE GLYCOL DICAPRYLATE/DICAPRATE | 0 | 90% | Enhanced skin absorption |
| ASCORBYL PALMITATE (VITAMIN C PALMITATE) | 1 | 88% | none identified |
| GLYCERYL MONOSTEARATE GLYCERYL STEARATE | 1 | 88% | none identified |
| ISOPROPYL PALMITATE | 1 | 87% | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| CITRUS MEDICA LIMONUM (LEMON) EXTRACT CITRUS MEDICA LIMONUM (LEMON) FRUIT EXTRACT | 0 | 100% | none identified |
| PPG-1 TRIDECETH-6 | 0 | 100% | none identified |
| SACCHARUM OFFICINARUM (SUGAR CANE) EXTRACT | 0 | 100% | none identified |
| PYRUS MALUS (APPLE) LEAF EXTRACT PYRUS MALUS (APPLE) FRUIT EXTRACT | 0 | 100% | none identified |
| PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES | 0 | 94% | none identified |
| WATER | 0 | 0% | innocuous |
Cancer*
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more in vitro tests on mammalian cells show positive mutation results | TOCOPHEROL, PROPYLENE GLYCOL, METHYLPARABEN, OLEIC ACID, BUTYLPARABEN | |
| Cancer - not classifiable/not likely to be human carcinogen | SALICYLIC ACID | |
| Cancer - limited evidence | ETHANOL |
Developmental/reproductive toxicity*
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show any effects at very low doses | BUTYLPARABEN | |
| One or more animal studies show reproductive effects at moderate doses | PROPYLENE GLYCOL, SALICYLIC ACID | |
| One or more animal studies show reproductive effects at high doses | LILIAL | |
| Limited evidence of reproductive toxicity | ETHANOL |
Violations, restrictions & warnings*
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Fragrance subject to restrictions: safe only within recommended use or concentration limitsn) | LILIAL, CAMELLIA SINENSIS (GREEN TEA) LEAF EXTRACT | |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | BIS-PEG-18 METHYL ETHER DIMETHYL SILANE, SALICYLIC ACID, PROPYLENE GLYCOL, LECITHIN | |
| Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Fragrance subject to restrictions: safe only within recommended use or concentration limitsn) | HYDROXYCITRONELLAL | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | SALICYLIC ACID, SALICYLIC ACID | |
| Violation of government restrictions - Banned or found unsafe for use in cosmetics | METHYLPARABEN |
Neurotoxicity*
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study | ETHANOL | |
| One or more animal studies show brain and nervous system effects at high doses | PROPYLENE GLYCOL | |
| One or more animal studies show brain and nervous system effects at moderate doses | OLEIC ACID, METHYLPARABEN, LECITHIN, LILIAL | |
| Moderate evidence of human neurotoxicity | FRAGRANCE | |
| One or more animal studies show brain and nervous system effects at low doses | SALICYLIC ACID |
Endocrine disruption*
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Associated with endocrine disruption | LILIAL | |
| One or more studies show weak endocrine disruption | ISOPROPYLPARABEN | |
| One or more animal studies show endocrine disruption at moderate doses | ISOBUTYLPARABEN | |
| Human any disruptor - strong evidence | METHYLPARABEN, BUTYLPARABEN |
Allergies/immunotoxicity*
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Limited evidence of skin and immune system toxicity | PROPYLENE GLYCOL | |
| Human skin toxicant - strong evidence | METHYLPARABEN, ISOPROPYLPARABEN, ISOBUTYLPARABEN, BUTYLPARABEN | |
| Possible human immune system toxicant | LILIAL | |
| Known human immune system toxicant | HYDROXYCITRONELLAL, FRAGRANCE |
Persistence and bioaccumulation*
*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not suspected to be bioaccumulative | ETHANOL | |
| Persistent, bioaccumulative in wildlife | SALICYLIC ACID |
Organ system toxicity (non-reproductive)*
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show metabolic effects at high doses (low dose studies may be unavailable for this ingredient) | PROPYLENE GLYCOL, ASCORBYL PALMITATE (VITAMIN C PALMITATE) | |
| One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient) | OLEIC ACID, GLYCERYL MONOSTEARATE | |
| Limited evidence of sense organ toxicity | BIS-PEG-18 METHYL ETHER DIMETHYL SILANE, ISOPROPYLPARABEN, ISOBUTYLPARABEN, BUTYLPARABEN, ETHANOL | |
| One or more animal studies show metabolic effects at low doses | SALICYLIC ACID, ISOPROPYL PALMITATE | |
| Limited evidence of any toxicity | SALIX ALBA (WHITE WILLOW) BARK EXTRACT | |
| Known human any toxicant | METHYLPARABEN |
Miscellaneous*
*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Occupational hazards related to handling | ETHANOL | |
| Ingredient not fully labeled - identity unknown | FRAGRANCE |
Multiple, additive exposure sources*
*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Designated as safe for general or specific, limited use in food | BIS-PEG-18 METHYL ETHER DIMETHYL SILANE, TOCOPHEROL, SALICYLIC ACID, PROPYLENE GLYCOL, CITRUS AURANTIUM DULCIS (ORANGE) FRUIT EXTRACT, OLEIC ACID, METHYLPARABEN, LECITHIN, ISOPROPYL PALMITATE, HYDROXYCITRONELLAL, GLYCERYL MONOSTEARATE, ETHANOL, CITRUS MEDICA LIMONUM (LEMON) EXTRACT, CAMELLIA SINENSIS (GREEN TEA) LEAF EXTRACT, BUTYLPARABEN, ASCORBYL PALMITATE (VITAMIN C PALMITATE) | |
| Used in food or as an additive with limited or no toxicity information available | SALICYLIC ACID, CITRUS AURANTIUM DULCIS (ORANGE) FRUIT EXTRACT, LECITHIN, ETHANOL |
Irritation (skin, eyes, or lungs)*
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show skin irritation at moderate doses | SALICYLIC ACID, BUTYLPARABEN | |
| One or more animal studies show skin irritation at low doses | OLEIC ACID, METHYLPARABEN, ISOPROPYL PALMITATE, HYDROXYCITRONELLAL, ETHANOL, LILIAL | |
| Human any irritant - strong evidence | products for use around the eyes, on the skin, or may be aerosolized (airborne) | ETHYLHEXYL PALMITATE |
| Classified as skin irritant | PROPYLENE GLYCOL |
Data gaps*
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Safety assessment was based on related chemical | ISOBUTYLPARABEN, PROPYLENE GLYCOL DICAPRYLATE/DICAPRATE, PROPYLENE GLYCOL, ISOPROPYLPARABEN | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | TOCOPHEROL, PROPYLENE GLYCOL DICAPRYLATE/DICAPRATE, METHYLPARABEN, OLEIC ACID, ISOPROPYL PALMITATE, BUTYLPARABEN, ETHYLHEXYL PALMITATE, GLYCERYL MONOSTEARATE | |
| Not assessed for safety in cosmetics by industry panel | PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES, PYRUS MALUS (APPLE) LEAF EXTRACT | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | ASCORBYL PALMITATE (VITAMIN C PALMITATE) | |
| Not assessed for safety in cosmetics by industry panel | BIS-PEG-18 METHYL ETHER DIMETHYL SILANE, SALIX ALBA (WHITE WILLOW) BARK EXTRACT, SACCHARUM OFFICINARUM (SUGAR CANE) EXTRACT, PPG-1 TRIDECETH-6, POLYQUATERNIUM-37, CITRUS AURANTIUM DULCIS (ORANGE) FRUIT EXTRACT, HYDROXYCITRONELLAL, FRAGRANCE, ETHANOL, CITRUS MEDICA LIMONUM (LEMON) EXTRACT, CAPRYLIC/ CAPRIC TRIGLYCERIDE, CAMELLIA SINENSIS (GREEN TEA) LEAF EXTRACT, LILIAL |
Occupational hazards*
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to high doses | ETHANOL |
Biochemical or cellular level changes*
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | ETHANOL, PROPYLENE GLYCOL | |
| Interferes with gene expresion | BUTYLPARABEN, METHYLPARABEN |
Copyright © 2010 by Environmental Working Group
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