GUERLAIN KIT FRENCH MANUCURE-KIT OF 2 NAIL ENAMELS & 1 TOP COAT, WHITE (2007 formulation) || Skin Deep: Cosmetic Safety Reviews

GUERLAIN KIT FRENCH MANUCURE-KIT OF 2 NAIL ENAMELS & 1 TOP COAT, WHITE (2007 FORMULATION)

last updated: 12/01/07 brand: Guerlain by Guerlain SA

SCORE

moderate hazard (out of 10)

84%

data gap

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COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company's animal testing policy is unknown.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Contamination concerns, Occupational hazards, Biochemical or cellular level changes

Note: This product formulation was obtained from the FDA VCRD.

Ingredients from packaging: BUTYL ACETATE, METHICONE, MINERAL OIL, HEAVY, CITRIC ACID, TITANIUM DIOXIDE, ACRYLATES COPOLYMER, ADIPIC ACID/FUMARIC ACID/PHTHALIC ACID/TRICYCLODECANE DIMETHANOL COPOLYMER, STEARALKONIUM BENTONITE, ETHYL ACETATE, NITROCELLULOSE, ACETYL TRIBUTYL CITRATE, ISOPROPYL ALCOHOL, ADIPIC ACID/NEOPENTYL GLYCOL/TRIMELLITIC ANHYDRIDE COPOLYMER, SUCROSE ACETATE ISOBUTYRATE, POLYETHYLENE

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ingredients

	score	data gap	concerns
POLYETHYLENE	6	69%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
ETHYL ACETATE	4	78%	Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
TITANIUM DIOXIDE (NON-NANO)	1	81%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards, Biochemical or cellular level changes
MINERAL OIL	2	73%	Organ system toxicity (non-reproductive), Occupational hazards
ISOPROPYL ALCOHOL	4	72%	Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
ACRYLATES COPOLYMER	3	75%	Contamination concerns (METHACRYLIC ACID, ACRYLIC ACID, 2-ETHYLHEXYL ACRYLATE)
CITRIC ACID	2	72%	Violations, restrictions & warnings
ACETYL TRIBUTYL CITRATE	2	88%	Multiple, additive exposure sources
SUCROSE ACETATE ISOBUTYRATE	1	86%	none identified
NITROCELLULOSE	1	94%	Organ system toxicity (non-reproductive)
BUTYL ACETATE	1	78%	Irritation (skin, eyes, or lungs), Occupational hazards
STEARALKONIUM BENTONITE	0	100%	none identified
ADIPIC ACID/FUMARIC ACID/PHTHALIC ACID/TRICYCLODECANE DIMETHANOL COPOLYMER	0	100%	none identified
METHICONE	0	99%	none identified
ADIPIC ACID/ NEOPENTYL GLYCOL/ TRIMELLITIC ANHYDRIDE COPOLYMER	0	94%	none identified

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show tumor formation at high doses		POLYETHYLENE, MINERAL OIL
One or more in vitro tests non-mammalian cells show positive mutation results		ETHYL ACETATE
One or more in vitro tests on mammalian cells show positive mutation results		TITANIUM DIOXIDE (NON-NANO), ISOPROPYL ALCOHOL

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Limited evidence of developmental toxicity		ISOPROPYL ALCOHOL
Human nervous system toxicant - moderate evidence		ETHYL ACETATE

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		POLYETHYLENE, ACRYLATES COPOLYMER
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		CITRIC ACID

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study		ETHYL ACETATE, BUTYL ACETATE
One or more animal studies show brain and nervous system effects at high doses		SUCROSE ACETATE ISOBUTYRATE, POLYETHYLENE, ISOPROPYL ALCOHOL

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show immune effects at low doses		TITANIUM DIOXIDE (NON-NANO)
Human immune system toxicant - moderate evidence		POLYETHYLENE

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show musculoskeletal effects at high doses (low dose studies may be unavailable for this ingredient)		CITRIC ACID, ACETYL TRIBUTYL CITRATE, POLYETHYLENE, SUCROSE ACETATE ISOBUTYRATE, ISOPROPYL ALCOHOL, MINERAL OIL
Limited evidence of sense organ toxicity		ETHYL ACETATE
One or more animal studies show cardiovascular effects at very low doses		TITANIUM DIOXIDE (NON-NANO)

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Designated as safe for general or specific, limited use in food		SUCROSE ACETATE ISOBUTYRATE, TITANIUM DIOXIDE (NON-NANO), MINERAL OIL, POLYETHYLENE, CITRIC ACID, ETHYL ACETATE, ISOPROPYL ALCOHOL, METHICONE
Used in food or as an additive with limited or no toxicity information available		ACETYL TRIBUTYL CITRATE
Designated as safe for general or specific, limited use in food		BUTYL ACETATE

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show skin irritation at high doses		SUCROSE ACETATE ISOBUTYRATE
One or more animal studies show skin irritation at moderate doses		TITANIUM DIOXIDE (NON-NANO), MINERAL OIL, ISOPROPYL ALCOHOL, CITRIC ACID
One or more animal studies show skin irritation at low doses		BUTYL ACETATE
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	POLYETHYLENE
Classified as irritant		ETHYL ACETATE

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not assessed for safety in cosmetics by industry panel		ADIPIC ACID/FUMARIC ACID/PHTHALIC ACID/TRICYCLODECANE DIMETHANOL COPOLYMER
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		ACETYL TRIBUTYL CITRATE
Not assessed for safety in cosmetics by industry panel		NITROCELLULOSE, STEARALKONIUM BENTONITE, SUCROSE ACETATE ISOBUTYRATE, TITANIUM DIOXIDE (NON-NANO), ADIPIC ACID/ NEOPENTYL GLYCOL/ TRIMELLITIC ANHYDRIDE COPOLYMER, CITRIC ACID, ISOPROPYL ALCOHOL, MINERAL OIL
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		BUTYL ACETATE, ETHYL ACETATE, METHICONE, POLYETHYLENE
Considered safe based on assumption of low absorption		ACRYLATES COPOLYMER, POLYETHYLENE
Missing safety data noted by cosmetic industry review		POLYETHYLENE

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to moderate doses		MINERAL OIL, TITANIUM DIOXIDE (NON-NANO)
Allowed workplace exposures restricted to high doses		BUTYL ACETATE, ETHYL ACETATE, ISOPROPYL ALCOHOL

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood		TITANIUM DIOXIDE (NON-NANO)
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		CITRIC ACID, POLYETHYLENE