COOL MINT LISTERINE POCKETMIST (2007 formulation) || Skin Deep: Cosmetic Safety Reviews

COOL MINT LISTERINE POCKETMIST (2007 FORMULATION)

last updated: 12/01/07 brand: Listerine by Pfizer

SCORE

moderate hazard (out of 10)

75%

data gap

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COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company conducts animal tests.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards

Note: This product formulation was obtained from the FDA VCRD.

Ingredients from packaging: ALCOHOL, THYMOL, WATER, GLYCERIN, POLOXAMER 407, FLAVOR, MENTHOL, POTASSIUM ACESULFAME, SUCRALOSE, EUCALYPTOL

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ingredients

	score	data gap	concerns
THYMOL	6	63%	Violations, restrictions & warnings, Neurotoxicity, Organ system toxicity (non-reproductive), Enhanced skin absorption, Occupational hazards
ETHANOL ALCOHOL	5	74%	Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards
FLAVOR	4	100%	Miscellaneous
POLOXAMER 407	2	82%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive)
MENTHOL	3	85%	Organ system toxicity (non-reproductive), Multiple, additive exposure sources
EUCALYPTOL	2	79%	none identified
GLYCERIN	2	74%	Organ system toxicity (non-reproductive), Occupational hazards
SUCRALOSE	1	95%	none identified
POTASSIUM ACESULFAME	0	94%	none identified
WATER	0	0%	innocuous

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more in vitro tests on mammalian cells show positive mutation results		THYMOL, SUCRALOSE, MENTHOL, GLYCERIN, EUCALYPTOL, ETHANOL

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive effects at high doses		GLYCERIN, EUCALYPTOL, ETHANOL
One or more animal studies show reproductive effects at moderate doses		THYMOL

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit)		THYMOL
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		THYMOL

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study		ETHANOL
One or more animal studies show brain and nervous system effects at high doses		POLOXAMER 407, EUCALYPTOL, GLYCERIN, MENTHOL
One or more animal studies show brain and nervous system effects at moderate doses		THYMOL

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show endocrine system disruption at high doses		THYMOL, GLYCERIN, EUCALYPTOL

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show kidney or renal system effects at high doses (low dose studies may be unavailable for this ingredient)		POLOXAMER 407
Limited evidence of gastrointestinal or liver toxicity		ETHANOL
One or more animal studies show gastrointestinal effects at moderate doses (low dose studies may be unavailable for this ingredient)		THYMOL, EUCALYPTOL
One or more animal studies show kidney or renal system effects at high doses (low dose studies may be unavailable for this ingredient)		GLYCERIN
One or more animal studies show sense organ effects at very low doses	products for use around the eyes, mouth, or lips	MENTHOL

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Occupational hazards related to handling		THYMOL, ETHANOL
Ingredient not fully labeled - identity unknown		FLAVOR

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Designated as safe for general or specific, limited use in food		POLOXAMER 407, THYMOL, SUCRALOSE, POTASSIUM ACESULFAME, MENTHOL, GLYCERIN, EUCALYPTOL, ETHANOL
Used in food or as an additive with limited or no toxicity information available		MENTHOL, ETHANOL

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not suspected to be an environmental toxin		ETHANOL
Wildlife and environmental toxicity		THYMOL

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show skin irritation at moderate doses		THYMOL, MENTHOL, GLYCERIN
One or more animal studies show skin irritation at low doses		ETHANOL

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Missing safety data noted by cosmetic industry review		THYMOL
Safety assessment was based on related chemical		POLOXAMER 407
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		POLOXAMER 407
Missing safety data noted by cosmetic industry review		POLOXAMER 407
Not assessed for safety in cosmetics by industry panel		FLAVOR, SUCRALOSE, POTASSIUM ACESULFAME, MENTHOL, GLYCERIN, EUCALYPTOL, ETHANOL

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to high doses		ETHANOL
Allowed workplace exposures restricted to low doses		THYMOL
Allowed workplace exposures restricted to moderate doses		GLYCERIN

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood		EUCALYPTOL
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		ETHANOL, GLYCERIN