

Compact for Safe Cosmetics
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Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: Neurotoxicity, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Contamination concerns, Occupational hazards |
Note: This product formulation was obtained from the FDA VCRD.
Ingredients from packaging: WATER, ALOE BARBADENSIS LEAF JUICE, TOCOPHERYL ACETATE, FDC RED #40, IODOPROPYNYL BUTYLCARBAMATE, DC RED #33, FDC YELLOW #5, CITRIC ACID, AMMONIUM LAURYL SULFATE, ISOBUTANE, COCAMIDOPROPYL BETAINE, FRAGRANCE, PROPANE, AMMONIUM COCOYL ISETHIONATE, DIAZOLIDINYL UREA, PANTHENOL
| score | data gap | concerns | |
| FRAGRANCE | 8 | 100% | Neurotoxicity, Allergies/immunotoxicity, Miscellaneous |
| ISOBUTANE | 6 | 79% | Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Contamination concerns (BUTADIENE), Occupational hazards |
| TARTRAZINE FDC YELLOW #5 | 5 | 70% | Violations, restrictions & warnings, Neurotoxicity, Organ system toxicity (non-reproductive) |
| IODOPROPYNYL BUTYLCARBAMATE | 4 | 65% | Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive) |
| DIAZOLIDINYL UREA | 6 | 59% | Allergies/immunotoxicity, Contamination concerns (FORMALDEHYDE) |
| COCAMIDOPROPYL BETAINE | 5 | 63% | Allergies/immunotoxicity, Contamination concerns (NITROSAMINES) |
| TOCOPHERYL ACETATE | 4 | 81% | Allergies/immunotoxicity, Contamination concerns (HYDROQUINONE) |
| PROPANE | 4 | 77% | Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Occupational hazards |
| D&C RED 33 | 4 | 75% | Violations, restrictions & warnings |
| CITRIC ACID | 3 | 72% | Violations, restrictions & warnings, Organ system toxicity (non-reproductive) |
| PANTHENOL | 2 | 88% | Multiple, additive exposure sources |
| FD&C RED 40 | 1 | 84% | none identified |
| AMMONIUM LAURYL SULFATE | 1 | 73% | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| ALOE BARBADENSIS (ALOE VERA) GEL ALOE BARBADENSIS LEAF JUICE | 1 | 72% | none identified |
| AMMONIUM COCOYL ISETHIONATE | 0 | 100% | none identified |
| WATER | 0 | 0% | innocuous |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more in vitro tests non-mammalian cells show positive mutation results | D&C RED 33 | |
| One or more in vitro tests on mammalian cells show positive mutation results | TOCOPHERYL ACETATE, TARTRAZINE, DIAZOLIDINYL UREA, FD&C RED 40 |
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show reproductive effects at high doses | TARTRAZINE, FD&C RED 40 | |
| One or more animal studies show any effects at moderate doses | ALOE BARBADENSIS (ALOE VERA) GEL |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | DIAZOLIDINYL UREA, IODOPROPYNYL BUTYLCARBAMATE, AMMONIUM LAURYL SULFATE, COCAMIDOPROPYL BETAINE, ALOE BARBADENSIS (ALOE VERA) GEL, D&C RED 33 | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | CITRIC ACID, IODOPROPYNYL BUTYLCARBAMATE, IODOPROPYNYL BUTYLCARBAMATE | |
| Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Color additive not approved by FDA for cosmetics used around eyes | products for use around the eyes | D&C RED 33 |
| Violation of government restrictions - Banned or found unsafe for use in cosmetics | TARTRAZINE |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show brain and nervous system effects at high doses | DIAZOLIDINYL UREA | |
| nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study | PROPANE | |
| Moderate evidence of human neurotoxicity | FRAGRANCE | |
| One or more animal studies show brain and nervous system effects at very low doses | TARTRAZINE |
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show endocrine system disruption at high doses | DIAZOLIDINYL UREA |
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Human skin toxicant - strong evidence | TOCOPHERYL ACETATE, PROPANE, ISOBUTANE | |
| Known human immune system toxicant | COCAMIDOPROPYL BETAINE, DIAZOLIDINYL UREA, FRAGRANCE | |
| Human any toxicant - strong evidence | IODOPROPYNYL BUTYLCARBAMATE |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show metabolic effects at high doses (low dose studies may be unavailable for this ingredient) | FD&C RED 40 | |
| Classified as expected to be toxic or harmful | ISOBUTANE | |
| One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient) | PANTHENOL, DIAZOLIDINYL UREA | |
| One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient) | PROPANE | |
| One or more animal studies show musculoskeletal effects at very low doses | TARTRAZINE, | |
| One or more animal studies show sense organ effects at very low doses | products for use around the eyes, mouth, or lips | CITRIC ACID |
| One or more animal studies show sense organ effects at low doses | products for use around the eyes, mouth, or lips | AMMONIUM LAURYL SULFATE |
| Limited evidence of gastrointestinal or liver toxicity | IODOPROPYNYL BUTYLCARBAMATE | |
| One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient) | ALOE BARBADENSIS (ALOE VERA) GEL, TOCOPHERYL ACETATE |
*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Occupational hazards related to handling | PROPANE, ISOBUTANE | |
| Ingredient not fully labeled - identity unknown | FRAGRANCE |
*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Designated as safe for general or specific, limited use in food | TOCOPHERYL ACETATE, TARTRAZINE, PROPANE, ISOBUTANE, FD&C RED 40, CITRIC ACID, ALOE BARBADENSIS (ALOE VERA) GEL | |
| Used in food or as an additive with limited or no toxicity information available | PROPANE, PANTHENOL, ISOBUTANE |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show skin irritation at high doses | IODOPROPYNYL BUTYLCARBAMATE | |
| One or more animal studies show skin irritation at very low doses | AMMONIUM LAURYL SULFATE | |
| One or more animal studies show skin irritation at moderate doses | CITRIC ACID | |
| Human any irritant - strong evidence | products for use around the eyes, on the skin, or may be aerosolized (airborne) | PROPANE, ISOBUTANE |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Missing safety data noted by cosmetic industry review | ALOE BARBADENSIS (ALOE VERA) GEL | |
| Safety assessment was based on related chemical | IODOPROPYNYL BUTYLCARBAMATE | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | PROPANE, TOCOPHERYL ACETATE, PANTHENOL, ISOBUTANE | |
| Not assessed for safety in cosmetics by industry panel | AMMONIUM COCOYL ISETHIONATE, TARTRAZINE, FRAGRANCE, CITRIC ACID |
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to high doses | ISOBUTANE, PROPANE |
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | CITRIC ACID |
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