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Compact for Safe Cosmetics
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Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: Neurotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes |
Ingredients from packaging: WATER, DIMETHICONE, MENTHOL, DIISOBUTYL ADIPATE, PEG/PPG-14/7 DIMETHYL ETHER, SODIUM CHLORIDE, SODIUM CITRATE, CAFFEINE, GLYCERYL OLEATE, ISOSTEARYL ALCOHOL, ETHYLHEXYL METHOXYCINNAMATE, ALCOHOL DENAT., PEG-40 SORBITAN PEROLEATE, BUTYLENE GLYCOL, CITRIC ACID, ALCOHOL, PROPYLENE GLYCOL, TRISODIUM EDTA, ALGAE EXTRACT, HOUTTUYNIA CORDATA EXTRACT, PHENOXYETHANOL, DC RED #17, FRAGRANCE, SWEET CLOVER (MELILOTUS OFFICINALIS) EXTRACT, BHT, TOCOPHEROL, PHOSPHORIC ACID, MINERAL OIL, GLYCERIN, NEOPENTYL GLYCOL DICAPRATE, MENTHYL LACTATE, XYLITOL, DIETHYLHEXYL SUCCINATE
| score | data gap | concerns | |
| FRAGRANCE | 8 | 100% | Neurotoxicity, Allergies/immunotoxicity, Miscellaneous |
| OCTINOXATE (OCTYL METHOXYCINNAMATE) ETHYLHEXYL METHOXYCINNAMATE (Active Ingredient) | 6 | 65% | Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Enhanced skin absorption, Biochemical or cellular level changes |
| PEG-40 SORBITAN PEROLEATE | 4 | 76% | Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE) |
| PEG/PPG-14/7 DIMETHYL ETHER | 4 | 76% | Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE) |
| BHT | 6 | 61% | Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards, Biochemical or cellular level changes |
| ETHANOL ALCOHOL | 5 | 74% | Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards |
| ALCOHOL DENATURED | 5 | 71% | Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards |
| SOLVENT RED 23 DC RED #17 | 5 | 70% | Violations, restrictions & warnings, Persistence and bioaccumulation, Biochemical or cellular level changes |
| CAFFEINE | 4 | 75% | Developmental/reproductive toxicity, Neurotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Biochemical or cellular level changes |
| MINERAL OIL | 4 | 73% | Cancer, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards |
| PHENOXYETHANOL | 4 | 67% | Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Occupational hazards |
| PROPYLENE GLYCOL | 4 | 60% | Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption |
| MENTHOL | 2 | 85% | Multiple, additive exposure sources |
| DIMETHICONE | 2 | 74% | Violations, restrictions & warnings |
| CITRIC ACID | 2 | 72% | Violations, restrictions & warnings |
| TOCOPHEROL | 2 | 87% | Contamination concerns (HYDROQUINONE) |
| PHOSPHORIC ACID | 2 | 79% | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| GLYCERIN | 2 | 74% | Organ system toxicity (non-reproductive), Occupational hazards |
| DIOCTYL SUCCINATE, ISO (BIS(2-ETHYLHEXYL) SUCCINATE) DIETHYLHEXYL SUCCINATE | 0 | 94% | none identified |
| ISOSTEARYL ALCOHOL | 0 | 93% | none identified |
| GLYCERYL OLEATE | 1 | 90% | Irritation (skin, eyes, or lungs) |
| DIISOBUTYL ADIPATE | 1 | 88% | none identified |
| XYLITOL | 1 | 88% | none identified |
| TRISODIUM EDTA | 1 | 86% | Enhanced skin absorption |
| BUTYLENE GLYCOL | 1 | 79% | Irritation (skin, eyes, or lungs) |
| HOUTTUYNIA CORDATA (TSI) EXTRACT HOUTTUYNIA CORDATA EXTRACT | 0 | 100% | none identified |
| MELILOTUS OFFICINALIS (SWEET CLOVER) EXTRACT SWEET CLOVER (MELILOTUS OFFICINALIS) EXTRACT | 0 | 100% | none identified |
| NEOPENTYL GLYCOL DICAPRATE | 0 | 100% | none identified |
| ALGAE EXTRACT | 0 | 94% | none identified |
| MENTHYL LACTATE | 0 | 94% | none identified |
| SODIUM CITRATE | 0 | 94% | none identified |
| SODIUM CHLORIDE | 0 | 0% | innocuous |
| WATER | 0 | 0% | innocuous |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show tumor formation at high doses | MINERAL OIL, | |
| One or more animal studies show tumor formation at high doses | TOCOPHEROL | |
| One or more in vitro tests non-mammalian cells show positive mutation results | SOLVENT RED 23, PHENOXYETHANOL | |
| One or more in vitro tests on mammalian cells show positive mutation results | SODIUM CHLORIDE, PROPYLENE GLYCOL, MENTHOL, GLYCERIN, ETHANOL, CAFFEINE, BHT, ALCOHOL DENATURED |
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show reproductive effects at high doses | GLYCERIN, ETHANOL, DIISOBUTYL ADIPATE, CAFFEINE, BUTYLENE GLYCOL, BHT, ALCOHOL DENATURED, | |
| One or more animal studies show developmental effects at high doses | OCTINOXATE (OCTYL METHOXYCINNAMATE) | |
| One or more animal studies show reproductive effects at moderate doses | PROPYLENE GLYCOL |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | PEG/PPG-14/7 DIMETHYL ETHER, PROPYLENE GLYCOL, PEG-40 SORBITAN PEROLEATE | |
| Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel | DIMETHICONE | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | CITRIC ACID, PHENOXYETHANOL | |
| Violation of government restrictions - Banned or found unsafe for use in cosmetics | SOLVENT RED 23 |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show brain and nervous system effects at high doses | XYLITOL | |
| nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study | ETHANOL | |
| One or more animal studies show brain and nervous system effects at high doses | MENTHOL, PROPYLENE GLYCOL, GLYCERIN | |
| One or more animal studies show brain and nervous system effects at moderate doses | PHOSPHORIC ACID | |
| One or more animal studies show brain and nervous system effects at high doses | BUTYLENE GLYCOL | |
| One or more animal studies show brain and nervous system effects at moderate doses | CAFFEINE, PHENOXYETHANOL, BHT | |
| Moderate evidence of human neurotoxicity | FRAGRANCE |
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Associated with endocrine disruption | OCTINOXATE (OCTYL METHOXYCINNAMATE) | |
| One or more animal studies show endocrine system disruption at high doses | CAFFEINE, GLYCERIN, BHT, BUTYLENE GLYCOL, ALCOHOL DENATURED |
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more human case studies show possible photoallergic effects | OCTINOXATE (OCTYL METHOXYCINNAMATE) | |
| Limited evidence of skin and immune system toxicity | PHENOXYETHANOL | |
| Known human immune system toxicant | FRAGRANCE | |
| Possible human immune system toxicant | products that may be aerosolized (airborne) | MINERAL OIL |
| Human skin toxicant - strong evidence | BHT | |
| Limited evidence of skin and immune system toxicity | PROPYLENE GLYCOL |
*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Persistent, bioaccumulative in wildlife | CAFFEINE, SOLVENT RED 23 | |
| Ingredient is suspected or measured to accumulate in people | OCTINOXATE (OCTYL METHOXYCINNAMATE) | |
| Not suspected to be bioaccumulative | ETHANOL |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient) | TRISODIUM EDTA, | |
| One or more animal studies show respiratory effects at high doses (low dose studies may be unavailable for this ingredient) | products that may be aerosolized (airborne) | PROPYLENE GLYCOL, PHENOXYETHANOL |
| One or more animal studies show musculoskeletal effects at high doses (low dose studies may be unavailable for this ingredient) | CITRIC ACID, ALCOHOL DENATURED, XYLITOL, GLYCERIN, | |
| One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient) | OCTINOXATE (OCTYL METHOXYCINNAMATE) | |
| One or more animal studies show liver effects at moderate doses (low dose studies may be unavailable for this ingredient) | SOLVENT RED 23, | |
| One or more animal studies show respiratory effects at moderate doses (low dose studies may be unavailable for this ingredient) | products that may be aerosolized (airborne) | PHOSPHORIC ACID |
| One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient) | BUTYLENE GLYCOL, MENTHOL, MINERAL OIL | |
| One or more animal studies show blood effects at low doses | BHT, CAFFEINE | |
| Limited evidence of gastrointestinal or liver toxicity | ETHANOL, PEG-40 SORBITAN PEROLEATE, PEG/PPG-14/7 DIMETHYL ETHER |
*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Occupational hazards related to handling | PHOSPHORIC ACID, ETHANOL, ALCOHOL DENATURED | |
| Ingredient not fully labeled - identity unknown | FRAGRANCE |
*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Designated as safe for general or specific, limited use in food | PEG/PPG-14/7 DIMETHYL ETHER, TOCOPHEROL, XYLITOL, SODIUM CITRATE, PEG-40 SORBITAN PEROLEATE, PHOSPHORIC ACID, PROPYLENE GLYCOL, GLYCERYL OLEATE, MENTHOL, SODIUM CHLORIDE, MENTHYL LACTATE, MINERAL OIL, CAFFEINE, CITRIC ACID, DIMETHICONE, ETHANOL, GLYCERIN, BUTYLENE GLYCOL, BHT, ALCOHOL DENATURED | |
| Used in food or as an additive with limited or no toxicity information available | MENTHOL, ETHANOL, ALCOHOL DENATURED |
*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not suspected to be an environmental toxin | ETHANOL | |
| Wildlife and environmental toxicity | OCTINOXATE (OCTYL METHOXYCINNAMATE) |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show skin irritation at moderate doses | MINERAL OIL, PHENOXYETHANOL, PHOSPHORIC ACID, PROPYLENE GLYCOL, SODIUM CHLORIDE, MENTHOL, GLYCERYL OLEATE, GLYCERIN, CITRIC ACID, CAFFEINE, BUTYLENE GLYCOL, BHT | |
| One or more animal studies show skin irritation at low doses | ETHANOL, ALCOHOL DENATURED |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Safety assessment was based on related chemical | PROPYLENE GLYCOL | |
| Insufficient data to determine safety | ALCOHOL DENATURED | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | TRISODIUM EDTA, TOCOPHEROL, PHENOXYETHANOL, ISOSTEARYL ALCOHOL, GLYCERYL OLEATE, DIMETHICONE, BUTYLENE GLYCOL, BHT | |
| Not assessed for safety in cosmetics by industry panel | DIOCTYL SUCCINATE, ISO (BIS(2-ETHYLHEXYL) SUCCINATE), SOLVENT RED 23, PEG/PPG-14/7 DIMETHYL ETHER, XYLITOL, SODIUM CITRATE, PHOSPHORIC ACID, PEG-40 SORBITAN PEROLEATE, MINERAL OIL, NEOPENTYL GLYCOL DICAPRATE, MENTHYL LACTATE, MENTHOL, HOUTTUYNIA CORDATA (TSI) EXTRACT, MELILOTUS OFFICINALIS (SWEET CLOVER) EXTRACT, DIISOBUTYL ADIPATE, ETHANOL, FRAGRANCE, GLYCERIN, CITRIC ACID, CAFFEINE, ALGAE EXTRACT |
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to high doses | ALCOHOL DENATURED | |
| Allowed workplace exposures restricted to moderate doses | MINERAL OIL, GLYCERIN | |
| Allowed workplace exposures restricted to low doses | PHOSPHORIC ACID, BHT, | |
| Allowed workplace exposures restricted to low doses | PHENOXYETHANOL | |
| Allowed workplace exposures restricted to high doses | ETHANOL |
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood | CAFFEINE | |
| One or more animal studies show biochemical changes at low doses where the human health implications are not yet well understood | SOLVENT RED 23 | |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | ALCOHOL DENATURED, BHT, CITRIC ACID, ETHANOL, GLYCERIN, PROPYLENE GLYCOL, XYLITOL | |
| Produces excess reactive oxygen species that can interfere with cellular signaling, cause mutations, lead to cell death and may be implicated in cardiovascular disease. | OCTINOXATE (OCTYL METHOXYCINNAMATE) |
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