LANCOME AQUA FUSION CONTINUOUS INFUSING MOISTURIZER NORMAL/DRY, SPF 15 (2007 FORMULATION)
last updated: 12/01/07 brand: Lancome by L'Oréal
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90% of facial moisturizer/treatments have lower concerns
96% of sunscreen: SPF 15-30s have lower concerns
COMPANY POLICIES
Compact for Safe Cosmetics
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Animal Testing Policy |
Sunscreen effectiveness* breakdown
| 6 | UVB hazard/exposure score |
| 8 | UVA hazard/exposure score |
| 3 | sunscreen instability |
*Note that the same active ingredient combination may score differently in two different products depending on the concentration of the ingredients and the mixture of inactive ingredients.
Active ingredient UV |
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 Product total |
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| OCTINOXATE (OCTYL METHOXYCINNAMATE) ( 6.7? %) |
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| ENSULIZOLE (PHENYLBENZIMIDAZOLE SULFONIC ACID) ( 1.8? %) |
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We have had to assume the percentage of the active ingredients in this product. If you own this product and it has the percentages printed on the package, you can help us fill in this missing information.
Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
 | Cancer |
| Developmental/reproductive toxicity |
| Violations, restrictions & warnings |
| Allergies/immunotoxicity |
| Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes |
Note from EWG: Unlike many other kinds of personal care products, sunscreen can provide health benefits, protecting against the sun's cancer-causing UV radiation. More than one million cases of skin cancer are diagnosed in the U.S. every year. Health officials recommend wearing sunscreen as one of many important steps to minimize skin cancer risk. (more sun safety tips)
Note: This product formulation was obtained from the FDA VCRD.
Ingredients from packaging: WATER, DIMETHICONE, AMMONIUM POLYACRYLOYLDIMETHYL TAURATE, STEARIC ACID, PALMITIC ACID, PHENOXYETHANOL, PEG-100 STEARATE, GLYCERYL STEARATE, CETYL ALCOHOL, TOCOPHERYL ACETATE, FRAGRANCE, ETHYLHEXYL METHOXYCINNAMATE, CHLORPHENESIN, METHYLPARABEN, DIMETHICONOL, PENTAERYTHRITYL TETRAISOSTEARATE, BIOSACCHARIDE GUM-1, DISODIUM EDTA, LACTIC ACID, STEARYL ALCOHOL, MYRISTYL ALCOHOL, CALCIUM GLUCONATE, GLYCERIN, ZINC GLUCONATE, SILICA DIMETHYL SILYLATE, MANNITOL, ARGININE, SERINE, PCA, SUCROSE, CITRULLINE, SODIUM CHONDROITIN SULFATE, GLYCOGEN, ALCOHOL DENAT., HISTIDINE, L-, MONOHYDROCHLORIDE, ALANINE, THREONINE, ATELOCOLLAGEN, FDC BLUE #1, GLUTAMIC ACID, LYSINE HCL, L-, MANGANESE GLUCONATE, SILICA, CYCLOHEXASILOXANE, PROPYLENE GLYCOL, PHENYLBENZIMIDAZOLE SULFONIC ACID, TRIETHANOLAMINE
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ingredients
| score | data gap | concerns | |
| METHYLPARABEN | 10 | 63% | Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes |
| FRAGRANCE | 8 | 100% | Neurotoxicity, Allergies/immunotoxicity, Miscellaneous |
| OCTINOXATE (OCTYL METHOXYCINNAMATE) ETHYLHEXYL METHOXYCINNAMATE (Active Ingredient) | 8 | 65% | Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Enhanced skin absorption, Biochemical or cellular level changes |
| SILICA | 1 | 69% | Biochemical or cellular level changes |
| PEG-100 STEARATE | 4 | 69% | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE) |
| TRIETHANOLAMINE | 6 | 58% | Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (NITROSAMINES), Occupational hazards |
| MANGANESE GLUCONATE | 5 | 84% | Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive) |
| ALCOHOL DENATURED | 5 | 71% | Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards |
| LACTIC ACID | 5 | 70% | Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| TOCOPHERYL ACETATE | 4 | 81% | Allergies/immunotoxicity, Contamination concerns (HYDROQUINONE) |
| PCA | 4 | 68% | Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Contamination concerns (NITROSAMINES) |
| PHENOXYETHANOL | 4 | 67% | Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| PROPYLENE GLYCOL | 4 | 60% | Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption |
| ARGININE | 3 | 79% | Neurotoxicity, Organ system toxicity (non-reproductive) |
| DISODIUM EDTA | 3 | 78% | Neurotoxicity, Organ system toxicity (non-reproductive), Enhanced skin absorption |
| ZINC GLUCONATE | 3 | 78% | Allergies/immunotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive) |
| DIMETHICONE | 2 | 74% | Violations, restrictions & warnings |
| ENSULIZOLE (PHENYLBENZIMIDAZOLE SULFONIC ACID) (Active Ingredient) | 3 | 74% | Violations, restrictions & warnings, Biochemical or cellular level changes |
| GLUTAMIC ACID | 2 | 85% | Organ system toxicity (non-reproductive), Biochemical or cellular level changes |
| FD&C BLUE 1 | 1 | 83% | none identified |
| CYCLOHEXASILOXANE | 1 | 82% | Persistence and bioaccumulation |
| GLYCERIN | 2 | 74% | Organ system toxicity (non-reproductive), Occupational hazards |
| STEARIC ACID | 2 | 74% | Neurotoxicity, Irritation (skin, eyes, or lungs) |
| CHLORPHENESIN | 2 | 72% | Violations, restrictions & warnings |
| MANNITOL | 1 | 92% | none identified |
| GLYCERYL MONOSTEARATE GLYCERYL STEARATE | 1 | 88% | none identified |
| GLYCOGEN | 1 | 88% | none identified |
| CETYL ALCOHOL | 1 | 87% | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| HISTIDINE HCL HISTIDINE, L-, MONOHYDROCHLORIDE | 1 | 87% | none identified |
| LYSINE HYDROCHLORIDE LYSINE HCL, L- | 1 | 87% | none identified |
| CALCIUM GLUCONATE | 1 | 86% | none identified |
| THREONINE | 1 | 86% | none identified |
| MYRISTYL ALCOHOL | 1 | 84% | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| STEARYL ALCOHOL | 1 | 84% | Irritation (skin, eyes, or lungs) |
| SODIUM CHONDROITIN SULFATE | 1 | 80% | none identified |
| PALMITIC ACID | 1 | 76% | Neurotoxicity |
| AMMONIUM POLYACRYLOYLDIMETHYL TAURATE | 0 | 100% | none identified |
| CITRULLINE | 0 | 100% | none identified |
| DIMETHICONOL | 0 | 100% | none identified |
| PENTAERYTHRITYL TETRAISOSTEARATE | 0 | 100% | none identified |
| SILICA DIMETHYL SILYLATE | 0 | 100% | none identified |
| ATELOCOLLAGEN | 0 | 100% | none identified |
| BIOSACCHARIDE GUM-1 | 0 | 100% | none identified |
| ALANINE | 0 | 94% | none identified |
| SERINE | 0 | 94% | none identified |
| SUCROSE | 0 | 0% | innocuous |
| WATER | 0 | 0% | innocuous |
Cancer*
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show tumor formation at high doses | MYRISTYL ALCOHOL, STEARYL ALCOHOL | |
| One or more in vitro tests non-mammalian cells show positive mutation results | PHENOXYETHANOL | |
| One or more animal studies show tumor formation at moderate doses | PEG-100 STEARATE | |
| One or more in vitro tests on mammalian cells show positive mutation results | ENSULIZOLE (PHENYLBENZIMIDAZOLE SULFONIC ACID) | |
| One or more in vitro tests on mammalian cells show positive mutation results | TOCOPHERYL ACETATE, THREONINE, SUCROSE, PROPYLENE GLYCOL, PCA, METHYLPARABEN, GLYCERIN, MANNITOL, GLUTAMIC ACID, DISODIUM EDTA, ARGININE | |
| Cancer - not classifiable/not likely to be human carcinogen | LACTIC ACID | |
| Cancer - limited evidence | ALCOHOL DENATURED | |
| Not likely to be carcinogenic in humans | STEARIC ACID, PALMITIC ACID | |
| Cancer - not classifiable/not likely to be human carcinogen | FD&C BLUE 1, TRIETHANOLAMINE |
Developmental/reproductive toxicity*
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show reproductive effects at high doses | SODIUM CHONDROITIN SULFATE, PEG-100 STEARATE, DISODIUM EDTA | |
| One or more animal studies show reproductive effects at moderate doses | OCTINOXATE (OCTYL METHOXYCINNAMATE) | |
| One or more animal studies show reproductive effects at moderate doses | ZINC GLUCONATE, PROPYLENE GLYCOL, GLYCOGEN, GLYCERIN, ARGININE | |
| Limited evidence of reproductive toxicity | ALCOHOL DENATURED | |
| Human nervous system toxicant - moderate evidence | MANGANESE GLUCONATE |
Violations, restrictions & warnings*
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | LACTIC ACID | |
| Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel | DIMETHICONE | |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | PEG-100 STEARATE, TRIETHANOLAMINE, PCA, PROPYLENE GLYCOL, LACTIC ACID | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit) | ENSULIZOLE (PHENYLBENZIMIDAZOLE SULFONIC ACID), CHLORPHENESIN | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit) | products for use around the eyes; products for use on the lips | OCTINOXATE (OCTYL METHOXYCINNAMATE) |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in cosmetics (concentration limit) | PHENOXYETHANOL, ENSULIZOLE (PHENYLBENZIMIDAZOLE SULFONIC ACID) | |
| Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Allowable pH limits | LACTIC ACID | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - prohibited for use in some types of cosmetics | CHLORPHENESIN | |
| Violation of government restrictions - Banned or found unsafe for use in cosmetics | METHYLPARABEN |
Neurotoxicity*
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show brain and nervous system effects at high doses | SODIUM CHONDROITIN SULFATE, THREONINE, PROPYLENE GLYCOL, PCA, LYSINE HYDROCHLORIDE, LACTIC ACID, CALCIUM GLUCONATE, HISTIDINE HCL, GLYCERIN, FD&C BLUE 1 | |
| One or more animal studies show brain and nervous system effects at moderate doses | PHENOXYETHANOL, METHYLPARABEN, GLUTAMIC ACID, CHLORPHENESIN | |
| One or more animal studies show brain and nervous system effects at low doses | PALMITIC ACID, DISODIUM EDTA | |
| One or more animal studies show brain and nervous system effects at very low doses | ARGININE, STEARIC ACID | |
| Strong evidence of human neurotoxicity | MANGANESE GLUCONATE | |
| Moderate evidence of human neurotoxicity | FRAGRANCE |
Endocrine disruption*
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show endocrine system disruption at high doses | SODIUM CHONDROITIN SULFATE, TRIETHANOLAMINE, PCA, GLYCERIN, DISODIUM EDTA, CYCLOHEXASILOXANE, ALCOHOL DENATURED | |
| Human any disruptor - strong evidence | METHYLPARABEN, OCTINOXATE (OCTYL METHOXYCINNAMATE) | |
| One or more animal studies show endocrine disruption at moderate doses | ARGININE |
Allergies/immunotoxicity*
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Limited evidence of skin and immune system toxicity | PHENOXYETHANOL | |
| One or more human case studies show possible photoallergic effects | OCTINOXATE (OCTYL METHOXYCINNAMATE) | |
| Limited evidence of skin and immune system toxicity | PROPYLENE GLYCOL | |
| Limited evidence of immune system toxicity | products for use on skin | PCA |
| Limited evidence of immune system toxicity | ZINC GLUCONATE | |
| Human skin toxicant - strong evidence | TOCOPHERYL ACETATE, METHYLPARABEN | |
| Known human immune system toxicant | TRIETHANOLAMINE, FRAGRANCE |
Persistence and bioaccumulation*
*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not suspected to be bioaccumulative | TRIETHANOLAMINE, ALCOHOL DENATURED | |
| Not suspected to be persistent | CETYL ALCOHOL, MYRISTYL ALCOHOL | |
| Ingredient is suspected or measured to accumulate in people | OCTINOXATE (OCTYL METHOXYCINNAMATE) | |
| Persistent, bioaccumulative in wildlife | ZINC GLUCONATE, CYCLOHEXASILOXANE |
Organ system toxicity (non-reproductive)*
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show metabolic effects at high doses (low dose studies may be unavailable for this ingredient) | HISTIDINE HCL, LYSINE HYDROCHLORIDE, THREONINE, | |
| One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient) | OCTINOXATE (OCTYL METHOXYCINNAMATE) | |
| One or more animal studies show gastrointestinal effects at high doses (low dose studies may be unavailable for this ingredient) | SODIUM CHONDROITIN SULFATE, CYCLOHEXASILOXANE, STEARIC ACID | |
| One or more animal studies show sense organ effects at moderate doses (low dose studies may be unavailable for this ingredient) | products for use around the eyes, mouth, or lips | SILICA, STEARYL ALCOHOL, PROPYLENE GLYCOL, CETYL ALCOHOL, MYRISTYL ALCOHOL |
| One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient) | FD&C BLUE 1 | |
| One or more animal studies show metabolic effects at moderate doses (low dose studies may be unavailable for this ingredient) | CALCIUM GLUCONATE, GLYCERYL MONOSTEARATE, TOCOPHERYL ACETATE | |
| One or more animal studies show broad systemic effects at low doses | PCA | |
| Limited evidence of sense organ toxicity | PEG-100 STEARATE | |
| One or more animal studies show broad systemic effects at low doses | DISODIUM EDTA | |
| One or more animal studies show sense organ effects at very low doses | products for use around the eyes, mouth, or lips | PHENOXYETHANOL, LACTIC ACID, ALCOHOL DENATURED |
| One or more animal studies show kidney or renal system effects at very low doses | GLYCERIN, GLUTAMIC ACID, ARGININE, ZINC GLUCONATE | |
| Possible human immune system toxicant | TRIETHANOLAMINE | |
| Known human respiratory toxicant | MANGANESE GLUCONATE, METHYLPARABEN |
Miscellaneous*
*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Occupational hazards related to handling | ALCOHOL DENATURED | |
| Ingredient not fully labeled - identity unknown | FRAGRANCE |
Multiple, additive exposure sources*
*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Designated as safe for general or specific, limited use in food | PEG-100 STEARATE, ZINC GLUCONATE, TRIETHANOLAMINE, TOCOPHERYL ACETATE, THREONINE, STEARYL ALCOHOL, STEARIC ACID, PROPYLENE GLYCOL, SERINE, MYRISTYL ALCOHOL, PALMITIC ACID, MANNITOL, METHYLPARABEN, MANGANESE GLUCONATE, LACTIC ACID, GLYCERIN, GLYCERYL MONOSTEARATE, FD&C BLUE 1, GLUTAMIC ACID, DISODIUM EDTA, DIMETHICONE, CETYL ALCOHOL, CALCIUM GLUCONATE, ARGININE, ALCOHOL DENATURED, ALANINE | |
| Used in food or as an additive with limited or no toxicity information available | ALCOHOL DENATURED |
Ecotoxicology*
*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Suspected to be an environmental toxin | MYRISTYL ALCOHOL, CETYL ALCOHOL | |
| Not suspected to be an environmental toxin | TRIETHANOLAMINE | |
| Wildlife and environmental toxicity | OCTINOXATE (OCTYL METHOXYCINNAMATE) | |
| Not suspected to be an environmental toxin | ALCOHOL DENATURED | |
| Wildlife and environmental toxicity | PCA |
Irritation (skin, eyes, or lungs)*
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show skin irritation at moderate doses | PALMITIC ACID, CALCIUM GLUCONATE, GLYCERIN | |
| One or more animal studies show skin irritation at low doses | STEARIC ACID, MYRISTYL ALCOHOL, METHYLPARABEN, ALCOHOL DENATURED | |
| One or more animal studies show skin irritation at very low doses | PEG-100 STEARATE, TRIETHANOLAMINE, LACTIC ACID, CETYL ALCOHOL | |
| Human any irritant - strong evidence | products for use around the eyes, on the skin, or may be aerosolized (airborne) | STEARYL ALCOHOL |
| Classified as skin irritant | PROPYLENE GLYCOL, PHENOXYETHANOL |
Data gaps*
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Safety assessment was based on related chemical | PEG-100 STEARATE, PROPYLENE GLYCOL | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | PALMITIC ACID, PHENOXYETHANOL, STEARIC ACID, TOCOPHERYL ACETATE, PEG-100 STEARATE | |
| Insufficient data to determine safety | ALCOHOL DENATURED | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | STEARYL ALCOHOL, MYRISTYL ALCOHOL, METHYLPARABEN, GLYCERYL MONOSTEARATE, DISODIUM EDTA, DIMETHICONE, CETYL ALCOHOL | |
| Not assessed for safety in cosmetics by industry panel | SODIUM CHONDROITIN SULFATE, BIOSACCHARIDE GUM-1, ATELOCOLLAGEN, ZINC GLUCONATE, THREONINE, SILICA DIMETHYL SILYLATE, SERINE, PENTAERYTHRITYL TETRAISOSTEARATE, MANNITOL, MANGANESE GLUCONATE, LYSINE HYDROCHLORIDE, HISTIDINE HCL, GLYCOGEN, GLYCERIN, GLUTAMIC ACID, FRAGRANCE, ENSULIZOLE (PHENYLBENZIMIDAZOLE SULFONIC ACID), DIMETHICONOL, CYCLOHEXASILOXANE, CITRULLINE, CHLORPHENESIN, AMMONIUM POLYACRYLOYLDIMETHYL TAURATE, ARGININE, CALCIUM GLUCONATE, ALANINE |
Occupational hazards*
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to high doses | ALCOHOL DENATURED | |
| No workplace limits set | LACTIC ACID | |
| Single case study detailing occupational hazards | MANGANESE GLUCONATE | |
| Allowed workplace exposures restricted to low doses | PHENOXYETHANOL | |
| Allowed workplace exposures restricted to moderate doses | GLYCERIN, SUCROSE, TRIETHANOLAMINE |
Biochemical or cellular level changes*
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Interferes with gene expresion | METHYLPARABEN | |
| Produces excess reactive oxygen species that can interfere with cellular signaling, cause mutations, lead to cell death and may be implicated in cardiovascular disease. | OCTINOXATE (OCTYL METHOXYCINNAMATE), ENSULIZOLE (PHENYLBENZIMIDAZOLE SULFONIC ACID) | |
| One or more animal studies show blood sugar changes at high doses where the human health implications are not yet well understood | PROPYLENE GLYCOL, PCA, GLYCERIN | |
| One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood | SILICA | |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | ALCOHOL DENATURED, ARGININE | |
| One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood | GLUTAMIC ACID |
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