Clairol Ultress Level 3, Custom Hair Color, Medium Ash Blonde 7A Kit (2006 formulation) || Skin Deep: Cosmetic Safety Reviews

CLAIROL ULTRESS LEVEL 3, CUSTOM HAIR COLOR, MEDIUM ASH BLONDE 7A KIT (2006 FORMULATION)

last updated: 05/01/06 brand: Clairol by Procter & Gamble

SCORE

high hazard (out of 10)

78%

data gap

BUY ONLINE/BETTER PRODUCTS

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68% of hair color and bleachings have lower concerns

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company conducts animal tests.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes

Ingredients from packaging: COLOUR CONCENTRATE GEL: WATER, OLEIC ACID, C12-15 PARETH-3, AMMONIUM HYDROXIDE, BEHENTRIMONIUM CHLORIDE, C11-15 PARETH-9, PROPYLENE GLYCOL, FRAGRANCE, STEARETH-21, CETYL ALCOHOL, POLYQUATERNIUM-47, PEG-150/STEARYL/SMDI COPOLYMER, STEARYL ALCOHOL, ERYTHORBIC ACID, EDTA, SODIUM SULFITE, SODIUM METASILICATE, MICA, TITANIUM DIOXIDE, P-AMINOPHENOL, P-PHENYLENEDIAMINE, RESORCINOL, M-AMINOPHENOL, IRON OXIDES, 1-NAPHTHOL, N,N-BIS (2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE. COLOUR CUSTOMIZER: WATER, OLEIC ACID, C12-15 PARETH-3, AMMONIUM HYDROXIDE, BEHENTRIMONIUM CHLORIDE, C11-15 PARETH-9, PROPYLENE GLYCOL, FRAGRANCE, STEARETH-21, CETYL ALCOHOL, POLYQUATERNIUM-47, PEG-150/STEARYL/SMDI COPOLYMER, STEARYL ALCOHOL, ERYTHORBIC ACID, EDTA, SODIUM SULFITE, SODIUM METASILICATE, MICA, TITANIUM DIOXIDE, RESORCINOL, IRON OXIDES, P-AMINOPHENOL. COLOUR CATALYST DEVELOPER: WATER, HYDROGEN PEROXIDE, GLYCERYL STEARATE, CETEARYL ALCOHOL, CETEARETH-20, EMULSIFYING WAX, SIMETHICONE, STEARAMIDOPROPYL DIMETHYLAMINE, PEG-75 LANOLIN, OLETH-10, OLETH-2, ETIDRONIC ACID. COLOURSHINE CONDITIONER: WATER, CETEARYL ALCOHOL, BEHENTRIMONIUM CHLORIDE, CYCLOMETHICONE, DISODIUM WHEATGERMAMPHODIACETATE, DIMETHICONE, AMODIMETHICONE, GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE, FRAGRANCE, POLYQUATERNIUM-7, CETRIMONIUM CHLORIDE, CITRIC ACID, TRIDECETH-12, DMDM HYDANTOIN, METHYLPARABEN, PHENOXYETHANOL, PROPYLPARABEN.

Directions from packaging: Important: Follow full directions enclosed.

Warnings from packaging: This product contains ingredients which may cause skin irritation on certain individuals and a preliminary test according to accompanying instructions should first be made. This product must not be used for dyeing the eyelashes or eyebrows; to do so may cause blindness. Keep out of the reach of children.

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ingredients

	score	data gap	concerns
METHYLPARABEN	10	63%	Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes
P-PHENYLENEDIAMINE	10	52%	Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
RESORCINOL	10	52%	Cancer, Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
DMDM HYDANTOIN	7	71%	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Contamination concerns (FORMALDEHYDE)
P-AMINOPHENOL	8	57%	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards
FRAGRANCE	8	100%	Neurotoxicity, Allergies/immunotoxicity, Miscellaneous
CETEARETH-20	5	71%	Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
1-NAPHTHOL	8	60%	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
PEG-150/ STEARYL ALCOHOL/ SMDI COPOLYMER PEG-150/STEARYL/SMDI COPOLYMER	4	76%	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
PEG-75 LANOLIN	4	75%	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
HYDROGEN PEROXIDE	3	65%	Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
M-AMINOPHENOL	6	65%	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Occupational hazards
PROPYLPARABEN	5	71%	Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
OLETH-10	3	87%	Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
OLETH-2	3	87%	Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
TITANIUM DIOXIDE (NON-NANO)	1	81%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards, Biochemical or cellular level changes
PHENOXYETHANOL	4	67%	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Occupational hazards
SODIUM METASILICATE	4	64%	Developmental/reproductive toxicity, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
PROPYLENE GLYCOL	4	60%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
SODIUM SULFITE	3	87%	Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
EDTA	3	78%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
MICA	3	75%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Occupational hazards
DIMETHICONE	2	74%	Violations, restrictions & warnings
CITRIC ACID	2	72%	Violations, restrictions & warnings
CETRIMONIUM CHLORIDE	3	71%	Allergies/immunotoxicity
N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE	3	69%	Cancer, Allergies/immunotoxicity
POLYQUATERNIUM-7	2	93%	Contamination concerns (ACRYLAMIDE)
IRON OXIDES	2	85%	Persistence and bioaccumulation, Enhanced skin absorption
CYCLOMETHICONE	2	83%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive)
OLEIC ACID	1	82%	Irritation (skin, eyes, or lungs)
AMMONIUM HYDROXIDE	2	81%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
ETIDRONIC ACID	2	79%	Endocrine disruption, Organ system toxicity (non-reproductive)
BEHENTRIMONIUM CHLORIDE	0	94%	none identified
STEARAMIDOPROPYL DIMETHYLAMINE	0	94%	none identified
CETEARYL ALCOHOL	0	93%	none identified
STEARETH-21	1	89%	none identified
GLYCERYL MONOSTEARATE GLYCERYL STEARATE	1	88%	none identified
C11-15 PARETH-9	1	88%	none identified
TRIDECETH-12	1	88%	Organ system toxicity (non-reproductive)
CETYL ALCOHOL	1	87%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
ERYTHORBIC ACID	1	87%	none identified
GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE	1	87%	none identified
C12-15 PARETH-3	1	86%	Organ system toxicity (non-reproductive)
STEARYL ALCOHOL	1	84%	Irritation (skin, eyes, or lungs)
DISODIUM WHEAT GERMAMPHODIACETATE	0	100%	none identified
EMULSIFYING WAX	0	100%	none identified
POLYQUATERNIUM-47	0	100%	none identified
SIMETHICONE	0	100%	none identified
AMODIMETHICONE	0	99%	none identified
WATER	0	0%	innocuous

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show tumor formation at high doses		STEARYL ALCOHOL
One or more in vitro tests non-mammalian cells show positive mutation results		PHENOXYETHANOL, AMMONIUM HYDROXIDE
One or more in vitro tests on mammalian cells show positive mutation results		TITANIUM DIOXIDE (NON-NANO), SODIUM SULFITE, PROPYLPARABEN, PROPYLENE GLYCOL, OLEIC ACID, METHYLPARABEN, ERYTHORBIC ACID, EDTA, CETRIMONIUM CHLORIDE
Cancer - limited evidence		N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE, M-AMINOPHENOL, 1-NAPHTHOL
Mutagen - limited evidence		P-AMINOPHENOL
Cancer - not classifiable/not likely to be human carcinogen		RESORCINOL, P-PHENYLENEDIAMINE, HYDROGEN PEROXIDE

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive effects at high doses		M-AMINOPHENOL, EDTA
One or more animal studies show reproductive effects at moderate doses		PROPYLENE GLYCOL, P-AMINOPHENOL
One or more animal studies show reproductive effects at low doses		SODIUM METASILICATE
One or more animal studies show reproductive effects at moderate doses		ETIDRONIC ACID, 1-NAPHTHOL
One or more animal studies show any effects at low doses		PROPYLPARABEN
Human nervous system toxicant - moderate evidence		P-PHENYLENEDIAMINE

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		PEG-75 LANOLIN, PEG-150/ STEARYL ALCOHOL/ SMDI COPOLYMER, SODIUM METASILICATE, PROPYLENE GLYCOL, CETRIMONIUM CHLORIDE, RESORCINOL, CETEARETH-20, P-PHENYLENEDIAMINE, P-AMINOPHENOL, N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE, 1-NAPHTHOL, M-AMINOPHENOL
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel		P-PHENYLENEDIAMINE, P-AMINOPHENOL, 1-NAPHTHOL, M-AMINOPHENOL, DIMETHICONE
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		P-PHENYLENEDIAMINE, CITRIC ACID, RESORCINOL, PHENOXYETHANOL, DMDM HYDANTOIN, DMDM HYDANTOIN
Violation of government restrictions - Banned or found unsafe for use in cosmetics		METHYLPARABEN

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show brain and nervous system effects at high doses		C12-15 PARETH-3, PROPYLENE GLYCOL, GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE, 1-NAPHTHOL
One or more animal studies show brain and nervous system effects at moderate doses		RESORCINOL, PHENOXYETHANOL, P-AMINOPHENOL, OLEIC ACID, METHYLPARABEN, M-AMINOPHENOL, ETIDRONIC ACID, EDTA, CETEARETH-20
One or more animal studies show brain and nervous system effects at low doses		SODIUM SULFITE
One or more animal studies show brain and nervous system effects at very low doses		HYDROGEN PEROXIDE
Moderate evidence of human neurotoxicity		FRAGRANCE
Strong evidence of human neurotoxicity		P-PHENYLENEDIAMINE

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show endocrine system disruption at high doses		P-PHENYLENEDIAMINE, N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE
One or more animal studies show endocrine disruption at moderate doses		1-NAPHTHOL
One or more animal studies show endocrine system disruption at high doses		HYDROGEN PEROXIDE
One or more studies show endocrine system disruption at low doses		ETIDRONIC ACID
Human any disruptor - strong evidence		RESORCINOL, PROPYLPARABEN, METHYLPARABEN

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Limited evidence of skin and immune system toxicity		PHENOXYETHANOL
One or more animal studies show gastrointestinal effects at moderate doses		MICA
One or more animal studies show immune effects at low doses		TITANIUM DIOXIDE (NON-NANO)
Human immune system toxicant - moderate evidence		SODIUM SULFITE
Limited evidence of skin and immune system toxicity		PROPYLENE GLYCOL
Human skin toxicant - strong evidence		SODIUM METASILICATE, PROPYLPARABEN, N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE, METHYLPARABEN, M-AMINOPHENOL, CETRIMONIUM CHLORIDE, 1-NAPHTHOL
Known human immune system toxicant		RESORCINOL, P-PHENYLENEDIAMINE, FRAGRANCE, P-AMINOPHENOL, DMDM HYDANTOIN

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not suspected to be bioaccumulative		TITANIUM DIOXIDE (NON-NANO), EDTA, AMMONIUM HYDROXIDE
Not suspected to be persistent		TRIDECETH-12, C12-15 PARETH-3, CETYL ALCOHOL
Persistent, bioaccumulative in wildlife		CYCLOMETHICONE
Persistent, bioaccumulative in wildlife and humans		IRON OXIDES, MICA

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Classified as expected to be toxic or harmful		C12-15 PARETH-3
One or more animal studies show metabolic effects at high doses (low dose studies may be unavailable for this ingredient)		PROPYLENE GLYCOL, TRIDECETH-12, CYCLOMETHICONE, CETYL ALCOHOL, C11-15 PARETH-9, STEARYL ALCOHOL, ERYTHORBIC ACID
One or more animal studies show liver effects at moderate doses (low dose studies may be unavailable for this ingredient)		CETEARETH-20, SODIUM METASILICATE, PHENOXYETHANOL, STEARETH-21, OLETH-2, OLETH-10, OLEIC ACID, N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE, GLYCERYL MONOSTEARATE, DMDM HYDANTOIN, CITRIC ACID, CETRIMONIUM CHLORIDE
Limited evidence of sense organ toxicity		PEG-75 LANOLIN, PROPYLPARABEN, PEG-150/ STEARYL ALCOHOL/ SMDI COPOLYMER
One or more animal studies show broad systemic effects at low doses		RESORCINOL, EDTA, AMMONIUM HYDROXIDE, ETIDRONIC ACID
One or more animal studies show gastrointestinal effects at very low doses		HYDROGEN PEROXIDE, TITANIUM DIOXIDE (NON-NANO)
Possible human respiratory toxicant		MICA, SODIUM SULFITE, P-AMINOPHENOL
Known human respiratory toxicant		P-PHENYLENEDIAMINE
Known human lung and skin toxicant	products that may be aerosolized (airborne); products for use on skin	1-NAPHTHOL
Known human any toxicant		METHYLPARABEN

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Occupational hazards related to handling		SODIUM METASILICATE, HYDROGEN PEROXIDE, AMMONIUM HYDROXIDE
Ingredient not fully labeled - identity unknown		FRAGRANCE

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Suspected to be an environmental toxin		TRIDECETH-12, C12-15 PARETH-3
Wildlife and environmental toxicity		AMMONIUM HYDROXIDE, M-AMINOPHENOL, P-AMINOPHENOL
Suspected to be an environmental toxin		CYCLOMETHICONE, CETYL ALCOHOL
Not suspected to be an environmental toxin		TITANIUM DIOXIDE (NON-NANO), EDTA
Wildlife and environmental toxicity		RESORCINOL, P-PHENYLENEDIAMINE, PROPYLPARABEN

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show skin irritation at moderate doses		TITANIUM DIOXIDE (NON-NANO), C11-15 PARETH-9, TRIDECETH-12
One or more animal studies show skin irritation at high doses		SODIUM SULFITE, C12-15 PARETH-3
One or more animal studies show skin irritation at moderate doses		P-AMINOPHENOL, M-AMINOPHENOL, CYCLOMETHICONE, CITRIC ACID
One or more animal studies show skin irritation at low doses		OLETH-2, OLETH-10, OLEIC ACID, CETEARETH-20, METHYLPARABEN
One or more animal studies show skin irritation at very low doses		CETYL ALCOHOL
Human skin irritant - moderate evidence		HYDROGEN PEROXIDE, AMMONIUM HYDROXIDE
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	STEARYL ALCOHOL, DMDM HYDANTOIN
Classified as irritant		SODIUM METASILICATE, PROPYLENE GLYCOL, PHENOXYETHANOL, RESORCINOL, P-PHENYLENEDIAMINE, EDTA, 1-NAPHTHOL

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Safety assessment was based on related chemical		PEG-75 LANOLIN, OLETH-10
Insufficient data to determine safety		P-AMINOPHENOL
Safety assessment was based on related chemical		OLETH-2, PROPYLENE GLYCOL, AMODIMETHICONE
Insufficient data to determine safety		1-NAPHTHOL
Safety assessment was based on related chemical		SODIUM METASILICATE
Insufficient data to determine safety		P-PHENYLENEDIAMINE
Missing safety data noted by cosmetic industry review		P-PHENYLENEDIAMINE
Insufficient data to determine safety		M-AMINOPHENOL
Missing safety data noted by cosmetic industry review		P-AMINOPHENOL, 1-NAPHTHOL
Considered safe based on assumption of low absorption		SODIUM METASILICATE
Missing safety data noted by cosmetic industry review		M-AMINOPHENOL
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		STEARYL ALCOHOL, PEG-75 LANOLIN, SODIUM SULFITE, PROPYLPARABEN, RESORCINOL, OLETH-2, PHENOXYETHANOL, SODIUM METASILICATE, POLYQUATERNIUM-7, P-PHENYLENEDIAMINE, P-AMINOPHENOL, OLEIC ACID, OLETH-10, N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE, METHYLPARABEN, M-AMINOPHENOL, GLYCERYL MONOSTEARATE, ERYTHORBIC ACID, EDTA, CETYL ALCOHOL, DMDM HYDANTOIN, DIMETHICONE, CYCLOMETHICONE, CETEARYL ALCOHOL
Not assessed for safety in cosmetics by industry panel		AMMONIUM HYDROXIDE, BEHENTRIMONIUM CHLORIDE, CITRIC ACID, DISODIUM WHEAT GERMAMPHODIACETATE, EMULSIFYING WAX, ETIDRONIC ACID, FRAGRANCE, GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE, HYDROGEN PEROXIDE, PEG-150/ STEARYL ALCOHOL/ SMDI COPOLYMER, POLYQUATERNIUM-47, SIMETHICONE, STEARAMIDOPROPYL DIMETHYLAMINE, TITANIUM DIOXIDE (NON-NANO), C11-15 PARETH-9, C12-15 PARETH-3
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		AMODIMETHICONE
Not assessed for safety in cosmetics by industry panel		STEARETH-21, TRIDECETH-12
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		1-NAPHTHOL

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to low doses		MICA
Allowed workplace exposures restricted to very low doses		P-PHENYLENEDIAMINE
Allowed workplace exposures restricted to low doses		TITANIUM DIOXIDE (NON-NANO), P-AMINOPHENOL, PHENOXYETHANOL, 1-NAPHTHOL, RESORCINOL, HYDROGEN PEROXIDE, M-AMINOPHENOL

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood		P-AMINOPHENOL
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		CITRIC ACID, CYCLOMETHICONE, HYDROGEN PEROXIDE, PROPYLENE GLYCOL
Interferes with gene expresion		METHYLPARABEN
One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood		ETIDRONIC ACID
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood		TITANIUM DIOXIDE (NON-NANO)