Clairol Herbal Essences True Intense Permanent Color, Extra Light Cool Blonde XL4 Kit (2006 formulation) || Skin Deep: Cosmetic Safety Reviews

CLAIROL HERBAL ESSENCES TRUE INTENSE PERMANENT COLOR, EXTRA LIGHT COOL BLONDE XL4 KIT (2006 FORMULATION)

last updated: 05/01/06 brand: Clairol by Procter & Gamble

SCORE

high hazard (out of 10)

81%

data gap

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98% of hair color and bleachings have lower concerns

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company conducts animal tests.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards

Ingredients from packaging: WATER, PROPYLENE GLYCOL, ETHANOLAMINE, SOYTRIMONIUM CHLORIDE, C12-15 PARETH-3, OLEIC ACID, AMMONIUM HYDROXIDE, ETHOXYDIGLYCOL, STEARETH-21, FRAGRANCE, OLEAMIDE MIPA, COCAMIDOPROPYL BETAINE, C11-15 PARETH-9, ANTHEMIS NOBILIS BETAINE, C11-15 PARETH-9, ANTHEMIS NOBILIS FLOWER EXTRACT, SPIRAEA ULMARIA FLOWER EXTRACT, MAGNOLIA ACUMINATA BARK EXTRACT, CRATAEGUS MONOGINA FRUIT EXTRACT, TOCOPHERYL ACETATE, HYDROLYZED VEGETABLE PROTEIN, PEG-150, STEARYL, SMDI COPOLYMER, POLYSORBATE 20, SODIUM METASILICATE, SODIUM SULFITE, ERYTHORBIC ACID, EDTA, P-AMINOPHENOL, RESORCINOL, M-AMINOPHENOL, 1-NAPHTHOL, 2-METHYLRESORCINOL, P-PHENYLENEDIAMINE, WATER, HYDROGEN PEROXIDE, GLYCERYL, CETEARYL ALCOHOL, EMULSIFYING WAX, STEARAMIDOPROPYL DIMETHYLAMINE, PEG-75 LANOLIN, CETEARETH-20, OLETH-10, OLETH-2, ETIDRONIC ACID, SIMETHICONE, WATER, CETEARYL ALCOHOL, BEHENTRIMONIUM CHLORIDE, CYCLOMETHICONE, TRIMETHYLSILYLAMODIMETHICONE, OLEYL ALCOHOL, SODIUM COCOAMPHOPROPIONATE, PANTHENOL, THYMUS VULGARIS EXTRACT THYME, TRITICUM VULGARE GERM OIL WHEAT, TOCOPHEROL, FRAGRANCE, CITRIC ACID, DISODIUM EDTA, PROPYLENE GLYCOL, DMDM HYDANTOIN, IODOPROPYNYL BUTYLCARBAMATE .

Directions from packaging: Easy to follow instructions included.

Warnings from packaging: This product contains ingredients which may cause skin irritation on certain individuals and a preliminary test according to accompanying directions should first be made. This product must not be used for dyeing the eyelashes or eyebrows; to do so may cause blindness.

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ingredients

	score	data gap	concerns
P-PHENYLENEDIAMINE	10	52%	Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
RESORCINOL	10	52%	Cancer, Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
DMDM HYDANTOIN	7	71%	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Contamination concerns (FORMALDEHYDE)
P-AMINOPHENOL	8	57%	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards
FRAGRANCE	8	100%	Neurotoxicity, Allergies/immunotoxicity, Miscellaneous
CETEARETH-20	5	71%	Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
PEG-150	5	69%	Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
1-NAPHTHOL	8	60%	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
ETHANOLAMINE	5	66%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
PEG-75 LANOLIN	4	75%	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
HYDROGEN PEROXIDE	3	65%	Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
IODOPROPYNYL BUTYLCARBAMATE	4	65%	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
M-AMINOPHENOL	6	65%	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Occupational hazards
COCAMIDOPROPYL BETAINE	5	63%	Allergies/immunotoxicity, Contamination concerns (NITROSAMINES)
OLETH-10	3	87%	Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
OLETH-2	3	87%	Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
TOCOPHERYL ACETATE	4	81%	Allergies/immunotoxicity, Contamination concerns (HYDROQUINONE)
SODIUM METASILICATE	4	64%	Developmental/reproductive toxicity, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
PROPYLENE GLYCOL	4	60%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
SODIUM SULFITE	3	87%	Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
DISODIUM EDTA	3	78%	Neurotoxicity, Organ system toxicity (non-reproductive), Enhanced skin absorption
EDTA	3	78%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
CITRIC ACID	2	72%	Violations, restrictions & warnings
PANTHENOL	2	88%	Multiple, additive exposure sources
TOCOPHEROL	2	87%	Contamination concerns (HYDROQUINONE)
2-METHYLRESORCINOL	2	84%	Allergies/immunotoxicity
CYCLOMETHICONE	2	83%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive)
ETHOXYDIGLYCOL	2	82%	Organ system toxicity (non-reproductive)
OLEIC ACID	1	82%	Irritation (skin, eyes, or lungs)
AMMONIUM HYDROXIDE	2	81%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
ETIDRONIC ACID	2	79%	Endocrine disruption, Organ system toxicity (non-reproductive)
GLYCERIN GLYCERYL	2	74%	Organ system toxicity (non-reproductive), Occupational hazards
THYMUS VULGARIS (COMMON THYME) EXTRACT THYMUS VULGARIS EXTRACT THYME	1	100%	Multiple, additive exposure sources
BEHENTRIMONIUM CHLORIDE	0	94%	none identified
OLEAMIDE MIPA	0	94%	none identified
STEARAMIDOPROPYL DIMETHYLAMINE	0	94%	none identified
SOYTRIMONIUM CHLORIDE	0	94%	none identified
CETEARYL ALCOHOL	0	93%	none identified
TRITICUM VULGARE (WHEAT) GERM OIL TRITICUM VULGARE GERM OIL WHEAT	1	90%	none identified
STEARETH-21	1	89%	none identified
C11-15 PARETH-9	1	88%	none identified
ERYTHORBIC ACID	1	87%	none identified
OLEYL ALCOHOL	1	87%	Irritation (skin, eyes, or lungs)
C12-15 PARETH-3	1	86%	Organ system toxicity (non-reproductive)
POLYSORBATE-20	1	84%	none identified
ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT ANTHEMIS NOBILIS FLOWER EXTRACT	1	80%	Enhanced skin absorption
CRATAEGUS MONOGINA FRUIT EXTRACT	0	100%	none identified
EMULSIFYING WAX	0	100%	none identified
HYDROLYZED VEGETABLE PROTEIN	0	100%	none identified
SIMETHICONE	0	100%	none identified
SPIRAEA ULMARIA (MEADOWSWEET) FLOWER EXTRACT SPIRAEA ULMARIA FLOWER EXTRACT	0	100%	none identified
STEAROYL STEARYL	0	100%	none identified
TRIMETHYLSILYLAMODIMETHICONE	0	100%	none identified
MAGNOLIA ACUMINATA BARK EXTRACT	0	100%	none identified
SODIUM COCOAMPHOPROPIONATE	0	99%	none identified
PPG-12/ SMDI COPOLYMER	0	94%	none identified
WATER	0	0%	innocuous

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more in vitro tests non-mammalian cells show positive mutation results		TRITICUM VULGARE (WHEAT) GERM OIL, ETHOXYDIGLYCOL, AMMONIUM HYDROXIDE
One or more in vitro tests on mammalian cells show positive mutation results		PEG-150, TOCOPHERYL ACETATE, SODIUM SULFITE, TOCOPHEROL, PROPYLENE GLYCOL, OLEIC ACID, GLYCERIN, ETHANOLAMINE, ERYTHORBIC ACID, EDTA, DISODIUM EDTA
Cancer - limited evidence		M-AMINOPHENOL, 1-NAPHTHOL
Mutagen - limited evidence		P-AMINOPHENOL
Cancer - not classifiable/not likely to be human carcinogen		RESORCINOL, P-PHENYLENEDIAMINE, HYDROGEN PEROXIDE

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive effects at high doses		POLYSORBATE-20, M-AMINOPHENOL, ETHOXYDIGLYCOL, ETHANOLAMINE, DISODIUM EDTA, EDTA
One or more animal studies show reproductive effects at moderate doses		PROPYLENE GLYCOL, P-AMINOPHENOL, GLYCERIN, ETIDRONIC ACID, 1-NAPHTHOL
One or more animal studies show reproductive effects at low doses		SODIUM METASILICATE
One or more animal studies show reproductive effects at very low doses		PEG-150
Human nervous system toxicant - moderate evidence		P-PHENYLENEDIAMINE

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		PEG-75 LANOLIN, PEG-150, SODIUM METASILICATE, PROPYLENE GLYCOL, IODOPROPYNYL BUTYLCARBAMATE, COCAMIDOPROPYL BETAINE, ETHANOLAMINE, CETEARETH-20, RESORCINOL, P-PHENYLENEDIAMINE, P-AMINOPHENOL, M-AMINOPHENOL, 1-NAPHTHOL
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel		P-PHENYLENEDIAMINE
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		P-PHENYLENEDIAMINE
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel		1-NAPHTHOL, M-AMINOPHENOL, P-AMINOPHENOL
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		CITRIC ACID, IODOPROPYNYL BUTYLCARBAMATE, DMDM HYDANTOIN, RESORCINOL, DMDM HYDANTOIN, IODOPROPYNYL BUTYLCARBAMATE

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show brain and nervous system effects at high doses		C12-15 PARETH-3, PROPYLENE GLYCOL, GLYCERIN, ETHOXYDIGLYCOL, 1-NAPHTHOL
One or more animal studies show brain and nervous system effects at moderate doses		RESORCINOL, P-AMINOPHENOL, OLEIC ACID, M-AMINOPHENOL, ETIDRONIC ACID, ETHANOLAMINE, EDTA, CETEARETH-20, ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT
One or more animal studies show brain and nervous system effects at low doses		SODIUM SULFITE, DISODIUM EDTA
One or more animal studies show brain and nervous system effects at very low doses		HYDROGEN PEROXIDE
Moderate evidence of human neurotoxicity		FRAGRANCE
Strong evidence of human neurotoxicity		P-PHENYLENEDIAMINE

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show endocrine system disruption at high doses		P-PHENYLENEDIAMINE, HYDROGEN PEROXIDE, GLYCERIN, DISODIUM EDTA, ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT
One or more animal studies show endocrine disruption at moderate doses		1-NAPHTHOL
One or more studies show endocrine system disruption at low doses		ETIDRONIC ACID
Human any disruptor - strong evidence		RESORCINOL

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Human immune system toxicant - moderate evidence		SODIUM SULFITE
Limited evidence of skin and immune system toxicity		PROPYLENE GLYCOL
Human skin toxicant - strong evidence		TOCOPHERYL ACETATE, SODIUM METASILICATE, 1-NAPHTHOL, ETHANOLAMINE, M-AMINOPHENOL, 2-METHYLRESORCINOL, IODOPROPYNYL BUTYLCARBAMATE
Known human immune system toxicant		RESORCINOL, P-PHENYLENEDIAMINE, P-AMINOPHENOL, FRAGRANCE, DMDM HYDANTOIN, COCAMIDOPROPYL BETAINE

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not suspected to be persistent		C12-15 PARETH-3
Not suspected to be bioaccumulative		PEG-150, AMMONIUM HYDROXIDE, EDTA
Persistent, bioaccumulative in wildlife		CYCLOMETHICONE

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient)		CYCLOMETHICONE, PROPYLENE GLYCOL
Classified as expected to be toxic or harmful		C12-15 PARETH-3
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient)		ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT, POLYSORBATE-20, C11-15 PARETH-9, PANTHENOL, ERYTHORBIC ACID
One or more animal studies show liver effects at moderate doses (low dose studies may be unavailable for this ingredient)		CETEARETH-20, SODIUM METASILICATE, STEARETH-21, TOCOPHERYL ACETATE, OLETH-2, OLEIC ACID, OLETH-10, DMDM HYDANTOIN, CITRIC ACID, 2-METHYLRESORCINOL
Limited evidence of sense organ toxicity		PEG-75 LANOLIN, IODOPROPYNYL BUTYLCARBAMATE, ETHOXYDIGLYCOL
One or more animal studies show broad systemic effects at low doses		DISODIUM EDTA, EDTA, RESORCINOL, AMMONIUM HYDROXIDE
One or more animal studies show gastrointestinal effects at very low doses		HYDROGEN PEROXIDE
One or more animal studies show blood effects at low doses		ETIDRONIC ACID
Possible human immune system toxicant		P-AMINOPHENOL
One or more animal studies show kidney or renal system effects at very low doses		GLYCERIN
Possible human immune system toxicant		SODIUM SULFITE, ETHANOLAMINE
One or more animal studies show broad systemic effects at very low doses		PEG-150
Known human respiratory toxicant		P-PHENYLENEDIAMINE
Known human lung and skin toxicant	products that may be aerosolized (airborne); products for use on skin	1-NAPHTHOL

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Occupational hazards related to handling		ETHANOLAMINE, HYDROGEN PEROXIDE, SODIUM METASILICATE
Ingredient not fully labeled - identity unknown		FRAGRANCE
Occupational hazards related to handling		AMMONIUM HYDROXIDE

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Designated as safe for general or specific, limited use in food		PEG-75 LANOLIN, PEG-150, TOCOPHERYL ACETATE, TOCOPHEROL, THYMUS VULGARIS (COMMON THYME) EXTRACT, SODIUM SULFITE, SODIUM METASILICATE, RESORCINOL, PROPYLENE GLYCOL, POLYSORBATE-20, OLEIC ACID, HYDROLYZED VEGETABLE PROTEIN, HYDROGEN PEROXIDE, ETHANOLAMINE, ETHOXYDIGLYCOL, ETIDRONIC ACID, GLYCERIN, DISODIUM EDTA, ERYTHORBIC ACID, CITRIC ACID, AMMONIUM HYDROXIDE, ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT
Used in food or as an additive with limited or no toxicity information available		PANTHENOL, THYMUS VULGARIS (COMMON THYME) EXTRACT

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not suspected to be an environmental toxin		PEG-150
Suspected to be an environmental toxin		CYCLOMETHICONE, C12-15 PARETH-3
Not suspected to be an environmental toxin		EDTA
Wildlife and environmental toxicity		RESORCINOL, P-PHENYLENEDIAMINE, P-AMINOPHENOL, M-AMINOPHENOL, AMMONIUM HYDROXIDE

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show skin irritation at high doses		C12-15 PARETH-3, SODIUM SULFITE, IODOPROPYNYL BUTYLCARBAMATE
One or more animal studies show skin irritation at moderate doses		PEG-150, C11-15 PARETH-9, TRITICUM VULGARE (WHEAT) GERM OIL, POLYSORBATE-20, P-AMINOPHENOL, M-AMINOPHENOL, GLYCERIN, CYCLOMETHICONE, ETHOXYDIGLYCOL, CITRIC ACID
One or more animal studies show skin irritation at low doses		OLETH-10
One or more animal studies show skin irritation at moderate doses		ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT
One or more animal studies show skin irritation at low doses		OLETH-2, CETEARETH-20, OLEIC ACID
Human skin irritant - moderate evidence		HYDROGEN PEROXIDE, ETHANOLAMINE, AMMONIUM HYDROXIDE
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	OLEYL ALCOHOL, DMDM HYDANTOIN
Classified as skin irritant		PROPYLENE GLYCOL, SODIUM METASILICATE, RESORCINOL, P-PHENYLENEDIAMINE, EDTA, 1-NAPHTHOL

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Safety assessment was based on related chemical		PEG-75 LANOLIN, PROPYLENE GLYCOL, OLETH-2
Insufficient data to determine safety		M-AMINOPHENOL, P-AMINOPHENOL, P-PHENYLENEDIAMINE
Safety assessment was based on related chemical		IODOPROPYNYL BUTYLCARBAMATE, OLETH-10, SODIUM METASILICATE, SODIUM COCOAMPHOPROPIONATE
Missing safety data noted by cosmetic industry review		P-AMINOPHENOL, P-PHENYLENEDIAMINE, M-AMINOPHENOL
Insufficient data to determine safety		1-NAPHTHOL
Considered safe based on assumption of low absorption		SODIUM METASILICATE
Missing safety data noted by cosmetic industry review		1-NAPHTHOL
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		PEG-75 LANOLIN, TOCOPHEROL, TOCOPHERYL ACETATE, TRITICUM VULGARE (WHEAT) GERM OIL, SODIUM METASILICATE, SODIUM SULFITE, RESORCINOL, POLYSORBATE-20, PANTHENOL, P-PHENYLENEDIAMINE, P-AMINOPHENOL, OLEYL ALCOHOL, OLETH-10, OLETH-2, M-AMINOPHENOL, OLEIC ACID, ETHOXYDIGLYCOL, ERYTHORBIC ACID, EDTA, DMDM HYDANTOIN, DISODIUM EDTA, CYCLOMETHICONE
Not assessed for safety in cosmetics by industry panel		HYDROLYZED VEGETABLE PROTEIN, OLEAMIDE MIPA, PPG-12/ SMDI COPOLYMER, SIMETHICONE, SPIRAEA ULMARIA (MEADOWSWEET) FLOWER EXTRACT, STEARAMIDOPROPYL DIMETHYLAMINE, STEAROYL, THYMUS VULGARIS (COMMON THYME) EXTRACT, TRIMETHYLSILYLAMODIMETHICONE, C11-15 PARETH-9, C12-15 PARETH-3, MAGNOLIA ACUMINATA BARK EXTRACT, SOYTRIMONIUM CHLORIDE, STEARETH-21
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		1-NAPHTHOL, 2-METHYLRESORCINOL, CETEARYL ALCOHOL, ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT
Not assessed for safety in cosmetics by industry panel		HYDROGEN PEROXIDE, GLYCERIN, FRAGRANCE, ETIDRONIC ACID, EMULSIFYING WAX, CRATAEGUS MONOGINA FRUIT EXTRACT, CITRIC ACID, BEHENTRIMONIUM CHLORIDE, ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT, AMMONIUM HYDROXIDE

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to low doses		HYDROGEN PEROXIDE, M-AMINOPHENOL, P-AMINOPHENOL, RESORCINOL
Allowed workplace exposures restricted to moderate doses		GLYCERIN
Allowed workplace exposures restricted to very low doses		P-PHENYLENEDIAMINE
Allowed workplace exposures restricted to low doses		1-NAPHTHOL, ETHANOLAMINE

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood		ETIDRONIC ACID, P-AMINOPHENOL
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		CITRIC ACID, CYCLOMETHICONE, GLYCERIN, HYDROGEN PEROXIDE, PROPYLENE GLYCOL