Clairol Herbal Essences True Intense Permanent Hair Color, Plush Plum (Radiant Burgundy) 48 Kit (2006 formulation) || Skin Deep: Cosmetic Safety Reviews

CLAIROL HERBAL ESSENCES TRUE INTENSE PERMANENT HAIR COLOR, PLUSH PLUM (RADIANT BURGUNDY) 48 KIT (2006 FORMULATION)

last updated: 05/01/06 brand: Clairol by Procter & Gamble

SCORE

high hazard (out of 10)

83%

data gap

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81% of hair color and bleachings have lower concerns

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company conducts animal tests.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards

Ingredients from packaging: PERMANENT COLOR GEL: WATER; PROPYLENE GLYCOL; ETHANOLAMINE; HEXYLENE GLYCOL; SOYTRIMONIUM CHLORIDE; ETHOXYDIGLYCOL; C11-15 PARETH-9; DILINOLEIC ACID; FRAGRANCE; COCAMIDOPROPYL BETAINE; OLEIC ACID; ASCORBIC ACID; PRUNUS SEROTINA (WILD CHERRY) FRUIT EXTRACT; HIBISCUS SABDARIFFA FLOWER EXTRACT; PASSIFLORA INCARNATA FLOWER EXTRACT; PAPAVER RHOEAS EXTRACT; VIOLA TRICOLOR EXTRACT; ROSA CANINA FRUIT EXTRACT; SIMMONDSIA CHINENSIS (JOJOBA) SEED EXTRACT; HYDROLYZED VEGETABLE PROTEIN; OLEAMIDE MIPA; PEG-150/STEARYL/SMDI COPOLYMER; C12-15 PARETH-3; OLETH-2; OLETH-10; POLYSORBATE 20; SODIUM SULFITE; EDTA; 4-AMINO-2-HYDROXYTOLUENE; P-PHENYLENEDIAMINE SULFATE; P-AMINOPHENOL. COLOR DEVELOPING CREME: WATER; HYDROGEN PEROXIDE; GLYCERYL STEARATE; CETEARYL ALCOHOL; EMULSIFYING WAX; STEARAMIDOPROPYL DIMETHYLAMINE; PEG-75 LANOLIN; CETEARETH-20; OLETH-10; OLETH-2; ETIDRONIC ACID; SIMETHICONE. COLOR SEAL CONDITIONER: WATER; CETEARYL ALCOHOL; BEHENTRIMONIUM CHLORIDE; CYCLOMETHICONE; TRIMETHYLSILYLAMODIMETHICONE; OLEYL ALCOHOL; SODIUM COCOAMPHOPROPIONATE; PANTHENOL; THYMUS VULGARIS (THYME) EXTRACT; TRITICUM VULGARE (WHEAT) GERM OIL; TOCOPHEROL; FRAGRANCE; CITRIC ACID; DISODIUM EDTA; PROPYLENE GLYCOL; DMDM HYDANTOIN; IODOPROPYNYL BUTYLCARBAMATE.

Directions from packaging: Easy to follow instructions inside.

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ingredients

	score	data gap	concerns
P-PHENYLENEDIAMINE	10	52%	Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
DMDM HYDANTOIN	7	71%	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Contamination concerns (FORMALDEHYDE)
P-AMINOPHENOL	8	57%	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards
FRAGRANCE	8	100%	Neurotoxicity, Allergies/immunotoxicity, Miscellaneous
CETEARETH-20	5	71%	Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
ETHANOLAMINE	5	66%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
PEG-150/ STEARYL ALCOHOL/ SMDI COPOLYMER PEG-150/STEARYL/SMDI COPOLYMER	4	76%	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
PEG-75 LANOLIN	4	75%	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
HYDROGEN PEROXIDE	3	65%	Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
IODOPROPYNYL BUTYLCARBAMATE	4	65%	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
4-AMINO-2-HYDROXYTOLUENE	5	67%	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity
HEXYLENE GLYCOL	4	67%	Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
COCAMIDOPROPYL BETAINE	5	63%	Allergies/immunotoxicity, Contamination concerns (NITROSAMINES)
OLETH-10	3	87%	Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
OLETH-2	3	87%	Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
PROPYLENE GLYCOL	4	60%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
SODIUM SULFITE	3	87%	Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
DISODIUM EDTA	3	78%	Neurotoxicity, Organ system toxicity (non-reproductive), Enhanced skin absorption
EDTA	3	78%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
CITRIC ACID	2	72%	Violations, restrictions & warnings
PANTHENOL	2	88%	Multiple, additive exposure sources
TOCOPHEROL	2	87%	Contamination concerns (HYDROQUINONE)
CYCLOMETHICONE	2	83%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive)
ETHOXYDIGLYCOL	2	82%	Organ system toxicity (non-reproductive)
OLEIC ACID	1	82%	Irritation (skin, eyes, or lungs)
ETIDRONIC ACID	2	79%	Endocrine disruption, Organ system toxicity (non-reproductive)
THYMUS VULGARIS (COMMON THYME) EXTRACT THYMUS VULGARIS (THYME) EXTRACT	1	100%	Multiple, additive exposure sources
BEHENTRIMONIUM CHLORIDE	0	94%	none identified
DILINOLEIC ACID	0	94%	none identified
OLEAMIDE MIPA	0	94%	none identified
STEARAMIDOPROPYL DIMETHYLAMINE	0	94%	none identified
SOYTRIMONIUM CHLORIDE	0	94%	none identified
CETEARYL ALCOHOL	0	93%	none identified
ASCORBIC ACID (VITAMIN C)	1	91%	none identified
TRITICUM VULGARE (WHEAT) GERM OIL	1	90%	none identified
GLYCERYL MONOSTEARATE GLYCERYL STEARATE	1	88%	none identified
C11-15 PARETH-9	1	88%	none identified
OLEYL ALCOHOL	1	87%	Irritation (skin, eyes, or lungs)
C12-15 PARETH-3	1	86%	Organ system toxicity (non-reproductive)
POLYSORBATE-20	1	84%	none identified
EMULSIFYING WAX	0	100%	none identified
HIBISCUS SABDARIFFA (ROSELLE) FLOWER EXTRACT HIBISCUS SABDARIFFA FLOWER EXTRACT	0	100%	none identified
HYDROLYZED VEGETABLE PROTEIN	0	100%	none identified
PAPAVER RHOEAS (CORN POPPY) EXTRACT PAPAVER RHOEAS EXTRACT	0	100%	none identified
PASSIFLORA INCARNATA (MAYPOPS) FLOWER EXTRACT PASSIFLORA INCARNATA FLOWER EXTRACT	0	100%	none identified
ROSA CANINA (DOG ROSE) FRUIT EXTRACT ROSA CANINA FRUIT EXTRACT	0	100%	none identified
SIMETHICONE	0	100%	none identified
SIMMONDSIA CHINENSIS (JOJOBA) SEED EXTRACT	0	100%	none identified
TRIMETHYLSILYLAMODIMETHICONE	0	100%	none identified
WILD PANSY EXTRACT VIOLA TRICOLOR EXTRACT	0	100%	none identified
PRUNUS SEROTINA (WILD CHERRY) FRUIT EXTRACT	0	100%	none identified
SODIUM COCOAMPHOPROPIONATE	0	99%	none identified
WATER	0	0%	innocuous

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more in vitro tests non-mammalian cells show positive mutation results		TRITICUM VULGARE (WHEAT) GERM OIL, ETHOXYDIGLYCOL
One or more in vitro tests on mammalian cells show positive mutation results		TOCOPHEROL, SODIUM SULFITE, PROPYLENE GLYCOL, OLEIC ACID, ETHANOLAMINE, EDTA, DISODIUM EDTA, ASCORBIC ACID (VITAMIN C)
Cancer - limited evidence		4-AMINO-2-HYDROXYTOLUENE
Mutagen - limited evidence		P-AMINOPHENOL
Cancer - not classifiable/not likely to be human carcinogen		P-PHENYLENEDIAMINE, HYDROGEN PEROXIDE

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive effects at high doses		POLYSORBATE-20, ETHOXYDIGLYCOL, ETHANOLAMINE, EDTA, DISODIUM EDTA
One or more animal studies show reproductive effects at moderate doses		PROPYLENE GLYCOL, P-AMINOPHENOL, ETIDRONIC ACID
Human nervous system toxicant - moderate evidence		P-PHENYLENEDIAMINE

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Determined safe for use in cosmetics, subject to concentration or use limitations - any		4-AMINO-2-HYDROXYTOLUENE, P-AMINOPHENOL, P-PHENYLENEDIAMINE, CETEARETH-20, COCAMIDOPROPYL BETAINE, ETHANOLAMINE, IODOPROPYNYL BUTYLCARBAMATE, PROPYLENE GLYCOL, PEG-75 LANOLIN
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel		P-PHENYLENEDIAMINE
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		PEG-150/ STEARYL ALCOHOL/ SMDI COPOLYMER
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel		4-AMINO-2-HYDROXYTOLUENE, P-AMINOPHENOL
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		P-PHENYLENEDIAMINE, IODOPROPYNYL BUTYLCARBAMATE, CITRIC ACID, DMDM HYDANTOIN, DMDM HYDANTOIN, IODOPROPYNYL BUTYLCARBAMATE

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study		HEXYLENE GLYCOL
One or more animal studies show brain and nervous system effects at high doses		C12-15 PARETH-3, PROPYLENE GLYCOL, ETHOXYDIGLYCOL
One or more animal studies show brain and nervous system effects at moderate doses		P-AMINOPHENOL
One or more animal studies show brain and nervous system effects at high doses		4-AMINO-2-HYDROXYTOLUENE
One or more animal studies show brain and nervous system effects at moderate doses		ETIDRONIC ACID, OLEIC ACID, ETHANOLAMINE, CETEARETH-20, EDTA
One or more animal studies show brain and nervous system effects at low doses		DISODIUM EDTA, SODIUM SULFITE
Strong evidence of human neurotoxicity		P-PHENYLENEDIAMINE
Moderate evidence of human neurotoxicity		FRAGRANCE
One or more animal studies show brain and nervous system effects at very low doses		HYDROGEN PEROXIDE

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show endocrine system disruption at high doses		HYDROGEN PEROXIDE, P-PHENYLENEDIAMINE, HEXYLENE GLYCOL, DISODIUM EDTA, 4-AMINO-2-HYDROXYTOLUENE
One or more studies show endocrine system disruption at low doses		ETIDRONIC ACID

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Human immune system toxicant - moderate evidence		SODIUM SULFITE
Human skin toxicant - strong evidence		4-AMINO-2-HYDROXYTOLUENE
Limited evidence of skin and immune system toxicity		PROPYLENE GLYCOL
Human skin toxicant - strong evidence		ETHANOLAMINE
Known human immune system toxicant		HEXYLENE GLYCOL, COCAMIDOPROPYL BETAINE
Human any toxicant - strong evidence		IODOPROPYNYL BUTYLCARBAMATE
Known human immune system toxicant		P-PHENYLENEDIAMINE, P-AMINOPHENOL, FRAGRANCE, DMDM HYDANTOIN

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not suspected to be bioaccumulative		EDTA
Not suspected to be persistent		C12-15 PARETH-3
Persistent, bioaccumulative in wildlife		CYCLOMETHICONE

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Classified as expected to be toxic or harmful		C12-15 PARETH-3
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient)		HEXYLENE GLYCOL, PROPYLENE GLYCOL, CYCLOMETHICONE, POLYSORBATE-20, C11-15 PARETH-9
One or more animal studies show liver effects at moderate doses (low dose studies may be unavailable for this ingredient)		CETEARETH-20
One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient)		PANTHENOL
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		OLETH-2, OLETH-10, GLYCERYL MONOSTEARATE, OLEIC ACID, DMDM HYDANTOIN, CITRIC ACID, 4-AMINO-2-HYDROXYTOLUENE
Limited evidence of sense organ toxicity		PEG-75 LANOLIN, PEG-150/ STEARYL ALCOHOL/ SMDI COPOLYMER, IODOPROPYNYL BUTYLCARBAMATE, ETHOXYDIGLYCOL
One or more animal studies show broad systemic effects at low doses		EDTA, DISODIUM EDTA, ETIDRONIC ACID
One or more animal studies show gastrointestinal effects at very low doses		HYDROGEN PEROXIDE
Possible human immune system toxicant		SODIUM SULFITE, P-AMINOPHENOL, ETHANOLAMINE
Known human respiratory toxicant		P-PHENYLENEDIAMINE

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Ingredient not fully labeled - identity unknown		FRAGRANCE
Occupational hazards related to handling		HYDROGEN PEROXIDE, ETHANOLAMINE

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Designated as safe for general or specific, limited use in food		PRUNUS SEROTINA (WILD CHERRY) FRUIT EXTRACT, PEG-75 LANOLIN, THYMUS VULGARIS (COMMON THYME) EXTRACT, TOCOPHEROL, SODIUM SULFITE, PROPYLENE GLYCOL, POLYSORBATE-20, PEG-150/ STEARYL ALCOHOL/ SMDI COPOLYMER, OLEIC ACID, HYDROLYZED VEGETABLE PROTEIN, HYDROGEN PEROXIDE, GLYCERYL MONOSTEARATE, ETIDRONIC ACID
Used in food or as an additive with limited or no toxicity information available		PANTHENOL, THYMUS VULGARIS (COMMON THYME) EXTRACT
Designated as safe for general or specific, limited use in food		ASCORBIC ACID (VITAMIN C), CITRIC ACID, DISODIUM EDTA, ETHANOLAMINE, ETHOXYDIGLYCOL

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Suspected to be an environmental toxin		C12-15 PARETH-3, CYCLOMETHICONE
Not suspected to be an environmental toxin		EDTA
Wildlife and environmental toxicity		P-PHENYLENEDIAMINE, P-AMINOPHENOL

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show skin irritation at high doses		C12-15 PARETH-3, IODOPROPYNYL BUTYLCARBAMATE, SODIUM SULFITE, 4-AMINO-2-HYDROXYTOLUENE
One or more animal studies show skin irritation at moderate doses		TRITICUM VULGARE (WHEAT) GERM OIL, C11-15 PARETH-9, P-AMINOPHENOL, POLYSORBATE-20, ETHOXYDIGLYCOL, CYCLOMETHICONE, CITRIC ACID
One or more animal studies show skin irritation at low doses		OLETH-2, OLETH-10, OLEIC ACID, CETEARETH-20
Human skin irritant - moderate evidence		HYDROGEN PEROXIDE, ETHANOLAMINE
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	OLEYL ALCOHOL, DMDM HYDANTOIN
Classified as skin irritant		PROPYLENE GLYCOL, P-PHENYLENEDIAMINE, HEXYLENE GLYCOL, EDTA

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Safety assessment was based on related chemical		PEG-75 LANOLIN, ASCORBIC ACID (VITAMIN C), OLETH-10, PROPYLENE GLYCOL, OLETH-2, SODIUM COCOAMPHOPROPIONATE
Insufficient data to determine safety		4-AMINO-2-HYDROXYTOLUENE
Safety assessment was based on related chemical		IODOPROPYNYL BUTYLCARBAMATE
Insufficient data to determine safety		P-AMINOPHENOL, P-PHENYLENEDIAMINE
Missing safety data noted by cosmetic industry review		4-AMINO-2-HYDROXYTOLUENE, P-AMINOPHENOL, P-PHENYLENEDIAMINE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		SODIUM SULFITE
Considered safe based on assumption of low absorption		4-AMINO-2-HYDROXYTOLUENE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		TRITICUM VULGARE (WHEAT) GERM OIL, TOCOPHEROL, PEG-75 LANOLIN, P-AMINOPHENOL, P-PHENYLENEDIAMINE, PANTHENOL, OLETH-10, OLETH-2, POLYSORBATE-20, OLEYL ALCOHOL, HEXYLENE GLYCOL, OLEIC ACID, GLYCERYL MONOSTEARATE, ETHOXYDIGLYCOL, EDTA, DISODIUM EDTA, DMDM HYDANTOIN, CYCLOMETHICONE, CETEARYL ALCOHOL, ASCORBIC ACID (VITAMIN C), 4-AMINO-2-HYDROXYTOLUENE
Not assessed for safety in cosmetics by industry panel		SOYTRIMONIUM CHLORIDE, PRUNUS SEROTINA (WILD CHERRY) FRUIT EXTRACT, C12-15 PARETH-3, C11-15 PARETH-9, WILD PANSY EXTRACT, TRIMETHYLSILYLAMODIMETHICONE, THYMUS VULGARIS (COMMON THYME) EXTRACT, STEARAMIDOPROPYL DIMETHYLAMINE, SIMMONDSIA CHINENSIS (JOJOBA) SEED EXTRACT, SIMETHICONE, ROSA CANINA (DOG ROSE) FRUIT EXTRACT, PEG-150/ STEARYL ALCOHOL/ SMDI COPOLYMER, PASSIFLORA INCARNATA (MAYPOPS) FLOWER EXTRACT, PAPAVER RHOEAS (CORN POPPY) EXTRACT, OLEAMIDE MIPA, HYDROLYZED VEGETABLE PROTEIN, HYDROGEN PEROXIDE, HIBISCUS SABDARIFFA (ROSELLE) FLOWER EXTRACT, FRAGRANCE, ETIDRONIC ACID, EMULSIFYING WAX, DILINOLEIC ACID, CITRIC ACID, BEHENTRIMONIUM CHLORIDE

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to very low doses		P-PHENYLENEDIAMINE
Allowed workplace exposures restricted to low doses		ETHANOLAMINE, HYDROGEN PEROXIDE, P-AMINOPHENOL

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood		ETIDRONIC ACID, P-AMINOPHENOL
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		CITRIC ACID, CYCLOMETHICONE, HYDROGEN PEROXIDE, PROPYLENE GLYCOL