Pro-Line Comb-Thru Texturizer, Regular Relaxer Kit (2006 formulation) || Skin Deep: Cosmetic Safety Reviews

PRO-LINE COMB-THRU TEXTURIZER, REGULAR RELAXER KIT (2006 FORMULATION)

last updated: 05/01/06 brand: Pro-Line by Pro-Line International

SCORE

high hazard (out of 10)

81%

data gap

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63% of hair relaxers have lower concerns

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company's animal testing policy is unknown.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes

Ingredients from packaging: WATER AQUA, PETROLATUM, POLYSORBATE 60, CETEARYL ALCOHOL, LANETH-15, LITHIUM HYDROXIDE, CETYL ALCOHOL, PEG-75 LANOLIN, HYDROLYZED COLLAGEN, SODIUM LAURETH SULFATE, PROPYLENE GLYCOL, PEG-150 DISTEARATE, TEA-LAURYL SULFATE, DECYL GLUCOSIDE, COCAMIDOPROPYL BETAINE, PANTHENOL, POLYSORBATE 20, POLYQUATERNIUM-39, TETRASODIUM EDTA, CITRIC ACID, ISOSTEARAMIDOPROPYL MORPHOLINE LACTATE, METHYLPARABEN, DIAZOLIDINYL UREA, FRAGRANCE PARFUM, YELLOW 5 CI 19140, MINERAL OIL PARAFFINUM LIQUIDUM, ACETAMIDE MEA, HYDROLYZED KERATIN, HYDROLYZED GLYCOSAMINOGLYCANS SODIUM COCOYL COLLAG, HYDROXYETHYLCELLULOSE, SORBITAN STEARATE, POLYQUATERNIUM-22, OLETH-3 PHOSPHATE, METHYLCHLOROISOTHIAZOLINONE, METHYLISOTHIAZOLINONE, CERESIN .

Directions from packaging: Instruction sheet included.

Warnings from packaging: + Read instructions inside kit carton carefully before using. Keep out of reach of children. Use only as directed. If accidentally swallowed, consult a physician immediately. Wear gloves when applying. This product contains Lithium Hydroxide. You must follow directions carefully to avoid skin and scalp burns, hair loss and eye injury. Keep this product and others away from eyes and mouth. If product gets into eye, rinse immediately and consult a physician. Do not use if scalp is irritated or injured. If hair has been previously texturized or relaxed, treat only the new growth as described in the instructions. If texturizer causes skin or scalp irritation, rinse out immediately and wash with an acid-balanced shampoo. If irritation persists or if hair loss occurs, consult a physician. Do not use on bleached hair. Do not use on permanently colored hair that is breaking, splitting or otherwise damaged. Do not use on curly permed or permanently waved hair until it has grown out. Contains Alkali agent. + Avoid contact with eyes. Can cause blindness. + Can cause hair breakage and/or loss. SEARCH TERMS: proline,Proline,Comb-Thru,Texturizer, Regular,Relaxer,Proline, Comb Thru Texturizer, Regular Relaxer,hair care,proline products,pro-line

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ingredients

	score	data gap	concerns
METHYLPARABEN	10	63%	Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes
FRAGRANCE	8	100%	Neurotoxicity, Allergies/immunotoxicity, Miscellaneous
PEG-75 LANOLIN	4	75%	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
PEG-150 DISTEARATE	4	73%	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
METHYLCHLOROISOTHIAZOLINONE	6	63%	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
METHYLISOTHIAZOLINONE	6	63%	Violations, restrictions & warnings, Allergies/immunotoxicity
DIAZOLIDINYL UREA	6	59%	Allergies/immunotoxicity, Contamination concerns (FORMALDEHYDE)
COCAMIDOPROPYL BETAINE	5	63%	Allergies/immunotoxicity, Contamination concerns (NITROSAMINES)
LITHIUM HYDROXIDE	4	86%	Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive)
SODIUM LAURETH SULFATE	4	86%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
MINERAL OIL	2	73%	Organ system toxicity (non-reproductive), Occupational hazards
PROPYLENE GLYCOL	4	60%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
OLETH-3 PHOSPHATE	3	94%	Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
CITRIC ACID	2	72%	Violations, restrictions & warnings
PETROLATUM	2	94%	Organ system toxicity (non-reproductive), Contamination concerns (PAHS)
PANTHENOL	2	88%	Multiple, additive exposure sources
TETRASODIUM EDTA	2	81%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards
HYDROLYZED KERATIN	2	75%	Violations, restrictions & warnings
ACETAMIDE MEA	1	73%	Contamination concerns (ACETAMIDE MEA)
TRIETHANOLAMINE LAURYL SULFATE TEA-LAURYL SULFATE	2	72%	Organ system toxicity (non-reproductive), Enhanced skin absorption, Contamination concerns (NITROSAMINES)
CERESIN	0	93%	none identified
CETEARYL ALCOHOL	0	93%	none identified
SORBITAN STEARATE	1	92%	none identified
HYDROLYZED COLLAGEN	0	88%	none identified
CETYL ALCOHOL	1	87%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
POLYSORBATE-20	1	84%	none identified
HYDROXYETHYLCELLULOSE	1	82%	none identified
POLYSORBATE-60	1	81%	none identified
DECYL GLUCOSIDE	0	100%	none identified
HYDROLYZED GLYCOSAMINOGLYCANS	0	100%	none identified
ISOSTEARAMIDOPROPYL MORPHOLINE LACTATE	0	100%	none identified
POLYQUATERNIUM-22	0	100%	none identified
POLYQUATERNIUM-39	0	100%	none identified
SODIUM COCOYL COLLAGEN AMINO ACID HYDROLYZED GLYCOSAMINOGLYCANS SODIUM COCOYL COLLAG	0	100%	none identified
LANETH-15	0	94%	none identified
WATER	0	0%	innocuous

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show tumor formation at high doses		POLYSORBATE-60, MINERAL OIL
One or more in vitro tests non-mammalian cells show positive mutation results		METHYLCHLOROISOTHIAZOLINONE
One or more in vitro tests on mammalian cells show positive mutation results		PROPYLENE GLYCOL, METHYLPARABEN, DIAZOLIDINYL UREA

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive effects at high doses		POLYSORBATE-60, HYDROXYETHYLCELLULOSE
One or more animal studies show reproductive effects at moderate doses		PROPYLENE GLYCOL
One or more animal studies show reproductive effects at high doses		POLYSORBATE-20
Human nervous system toxicant - moderate evidence		LITHIUM HYDROXIDE

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		CITRIC ACID
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		PEG-75 LANOLIN, TRIETHANOLAMINE LAURYL SULFATE, PROPYLENE GLYCOL, METHYLISOTHIAZOLINONE, PEG-150 DISTEARATE, DIAZOLIDINYL UREA, METHYLCHLOROISOTHIAZOLINONE, ACETAMIDE MEA, COCAMIDOPROPYL BETAINE
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		HYDROLYZED KERATIN, METHYLISOTHIAZOLINONE, METHYLCHLOROISOTHIAZOLINONE, METHYLCHLOROISOTHIAZOLINONE, METHYLCHLOROISOTHIAZOLINONE, METHYLISOTHIAZOLINONE
Violation of government restrictions - Banned or found unsafe for use in cosmetics		METHYLPARABEN

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more in vitro tests on mammalian cells demonstrate neurotoxicity		METHYLISOTHIAZOLINONE
One or more animal studies show brain and nervous system effects at high doses		PROPYLENE GLYCOL, DIAZOLIDINYL UREA, HYDROXYETHYLCELLULOSE
One or more animal studies show brain and nervous system effects at moderate doses		METHYLPARABEN
Strong evidence of human neurotoxicity		LITHIUM HYDROXIDE
Moderate evidence of human neurotoxicity		FRAGRANCE

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show endocrine system disruption at high doses		DIAZOLIDINYL UREA
Human any disruptor - strong evidence		METHYLPARABEN

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Limited evidence of skin and immune system toxicity		PROPYLENE GLYCOL
Known human immune system toxicant		METHYLISOTHIAZOLINONE
Human skin toxicant - strong evidence		METHYLPARABEN
Known human immune system toxicant		METHYLCHLOROISOTHIAZOLINONE, COCAMIDOPROPYL BETAINE, FRAGRANCE, DIAZOLIDINYL UREA

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Classified as expected to be toxic or harmful		TRIETHANOLAMINE LAURYL SULFATE, PETROLATUM
One or more animal studies show cardiovascular effects at high doses (low dose studies may be unavailable for this ingredient)		CETYL ALCOHOL, POLYSORBATE-20, PROPYLENE GLYCOL, HYDROXYETHYLCELLULOSE, PANTHENOL, MINERAL OIL, DIAZOLIDINYL UREA, ACETAMIDE MEA
One or more animal studies show kidney or renal system effects at moderate doses (low dose studies may be unavailable for this ingredient)		TETRASODIUM EDTA, SODIUM LAURETH SULFATE, POLYSORBATE-60, CITRIC ACID
Limited evidence of sense organ toxicity		PEG-75 LANOLIN, PEG-150 DISTEARATE
One or more animal studies show liver effects at low doses		LITHIUM HYDROXIDE
Possible human immune system toxicant		METHYLCHLOROISOTHIAZOLINONE
Known human any toxicant		METHYLPARABEN

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Ingredient not fully labeled - identity unknown		FRAGRANCE

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Designated as safe for general or specific, limited use in food		PEG-75 LANOLIN, TETRASODIUM EDTA, SORBITAN STEARATE, PROPYLENE GLYCOL, POLYSORBATE-60, POLYSORBATE-20, PETROLATUM, PEG-150 DISTEARATE, MINERAL OIL, METHYLPARABEN, CITRIC ACID, CETYL ALCOHOL
Used in food or as an additive with limited or no toxicity information available		PANTHENOL

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Suspected to be an environmental toxin		CETYL ALCOHOL
Not suspected to be an environmental toxin		PETROLATUM

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show skin irritation at high doses		TRIETHANOLAMINE LAURYL SULFATE
One or more animal studies show skin irritation at moderate doses		SORBITAN STEARATE, POLYSORBATE-20, MINERAL OIL, CITRIC ACID, ACETAMIDE MEA
One or more animal studies show skin irritation at low doses		METHYLPARABEN, TETRASODIUM EDTA
One or more animal studies show skin irritation at very low doses		CETYL ALCOHOL
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	SODIUM LAURETH SULFATE
Classified as skin irritant		PROPYLENE GLYCOL

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Safety assessment was based on related chemical		PEG-150 DISTEARATE, PEG-75 LANOLIN, PROPYLENE GLYCOL
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		PEG-75 LANOLIN, HYDROLYZED COLLAGEN, PEG-150 DISTEARATE, TETRASODIUM EDTA, SODIUM LAURETH SULFATE, METHYLPARABEN, POLYSORBATE-20, POLYSORBATE-60, SORBITAN STEARATE, PANTHENOL, HYDROXYETHYLCELLULOSE, CETEARYL ALCOHOL, CETYL ALCOHOL, CERESIN
Not assessed for safety in cosmetics by industry panel		SODIUM COCOYL COLLAGEN AMINO ACID, POLYQUATERNIUM-39, POLYQUATERNIUM-22, PETROLATUM, OLETH-3 PHOSPHATE, MINERAL OIL, LITHIUM HYDROXIDE, LANETH-15, ISOSTEARAMIDOPROPYL MORPHOLINE LACTATE, HYDROLYZED KERATIN, HYDROLYZED GLYCOSAMINOGLYCANS, CITRIC ACID, DECYL GLUCOSIDE, FRAGRANCE

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
No workplace limits set		LITHIUM HYDROXIDE
Allowed workplace exposures restricted to low doses		TETRASODIUM EDTA
Allowed workplace exposures restricted to moderate doses		MINERAL OIL

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		CITRIC ACID, PROPYLENE GLYCOL
Interferes with gene expresion		METHYLPARABEN