Oral-B Rembrandt Premium Mouth Rinse Stain Therapy (2006 formulation) || Skin Deep: Cosmetic Safety Reviews

ORAL-B REMBRANDT PREMIUM MOUTH RINSE STAIN THERAPY (2006 FORMULATION)

last updated: 05/01/06 brand: Oral-B by Procter & Gamble

SCORE

moderate hazard (out of 10)

72%

data gap

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61% of breath fresheners have lower concerns
72% of mouthwashs have lower concerns
49% of tooth whitenings have lower concerns

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company conducts animal tests.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Organ system toxicity (non-reproductive), Miscellaneous, Irritation (skin, eyes, or lungs), Contamination concerns, Occupational hazards

Ingredients from packaging: ACTIVE INGREDIENTS: PURIFIED WATER, GLYCERIN, HYDROGEN PEROXIDE SOLUTION, SODIUM CITRATE, CREMOPHOR RH 40, FLAVOR, COCAMIDOPROPYL BETAINE, CITRIC ACID, SODIUM BENZOATE, SODIUM SACCHARIN, SODIUM HYDROXIDE.

Directions from packaging: Use once a day after brushing your teeth with any Rembrandt Whitening Toothpaste. Rinse mouth for 1 minute and then spit out. Do not swallow. For maximum benefit, do not eat or drink for 30 minutes after rinsing.

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ingredients

	score	data gap	concerns
HYDROGEN PEROXIDE	6	65%	Violations, restrictions & warnings, Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
COCAMIDOPROPYL BETAINE	5	63%	Allergies/immunotoxicity, Contamination concerns (NITROSAMINES)
FLAVOR	4	100%	Miscellaneous
SODIUM HYDROXIDE	3	77%	Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
CITRIC ACID	3	72%	Violations, restrictions & warnings, Organ system toxicity (non-reproductive)
SODIUM SACCHARIN	2	80%	Neurotoxicity
GLYCERIN	2	74%	Organ system toxicity (non-reproductive), Occupational hazards
SODIUM BENZOATE	2	69%	Organ system toxicity (non-reproductive)
CREMOPHOR RH 40	0	100%	none identified
SODIUM CITRATE	0	94%	none identified
WATER (PURIFIED)	0	0%	innocuous

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more in vitro tests on mammalian cells show positive mutation results		SODIUM SACCHARIN, SODIUM HYDROXIDE, SODIUM BENZOATE, GLYCERIN
Cancer - not classifiable/not likely to be human carcinogen		HYDROGEN PEROXIDE

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive effects at high doses		SODIUM SACCHARIN, SODIUM BENZOATE
One or more animal studies show reproductive effects at moderate doses		GLYCERIN

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		SODIUM BENZOATE
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		CITRIC ACID
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		COCAMIDOPROPYL BETAINE
Violation of government restrictions - Banned or found unsafe for use in cosmetics	product not intended as hair dye/bleach	HYDROGEN PEROXIDE

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show brain and nervous system effects at high doses		GLYCERIN
One or more animal studies show brain and nervous system effects at moderate doses		SODIUM BENZOATE
One or more animal studies show brain and nervous system effects at very low doses		SODIUM SACCHARIN, SODIUM HYDROXIDE, HYDROGEN PEROXIDE

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show endocrine system disruption at high doses		HYDROGEN PEROXIDE, GLYCERIN

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Known human immune system toxicant		COCAMIDOPROPYL BETAINE

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show metabolic effects at very low doses		SODIUM HYDROXIDE,
One or more animal studies show sense organ effects at very low doses	products for use around the eyes, mouth, or lips	CITRIC ACID, HYDROGEN PEROXIDE
One or more animal studies show broad systemic effects at low doses		SODIUM BENZOATE
One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient)		SODIUM SACCHARIN
One or more animal studies show kidney or renal system effects at very low doses		GLYCERIN

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Occupational hazards related to handling		SODIUM HYDROXIDE, HYDROGEN PEROXIDE
Ingredient not fully labeled - identity unknown		FLAVOR

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show skin irritation at high doses		SODIUM BENZOATE
One or more animal studies show skin irritation at moderate doses		GLYCERIN, CITRIC ACID
One or more animal studies show skin irritation at very low doses		SODIUM HYDROXIDE
Human skin irritant - moderate evidence		HYDROGEN PEROXIDE

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not assessed for safety in cosmetics by industry panel		CREMOPHOR RH 40, FLAVOR, SODIUM SACCHARIN, SODIUM HYDROXIDE, SODIUM CITRATE, HYDROGEN PEROXIDE, GLYCERIN, CITRIC ACID

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
No workplace limits set		SODIUM HYDROXIDE
Allowed workplace exposures restricted to moderate doses		GLYCERIN
Allowed workplace exposures restricted to low doses		HYDROGEN PEROXIDE

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		SODIUM BENZOATE, HYDROGEN PEROXIDE, GLYCERIN, CITRIC ACID