

Compact for Safe Cosmetics
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Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Organ system toxicity (non-reproductive), Miscellaneous, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes |
Ingredients from packaging: Active Ingredients:Permethrin 280mg (1%). Inactive Ingredients:Balsam Canada, Cetyl Alcohol, Citric Acid, FD&C Yellow 6, Fragrance, Hydrolyzed Animal Protein, Hydroxyethylcellulose, Isopropyl Alcohol 5.6g (20%), Methylparaben 56mg (0.2%), Polyoxyethylene 10 Cetyl Ether, Propylene Glycol, Propylparaben 22mg (0.8%), Stearalkonium Chloride, Water.
Directions from packaging: Read all directions in the Consumer Information Insert and warnings before use. Keep the carton. If contains important information. Inspect All household members should be checked by another person for lice and/or nits (eggs). Use a magnifying glass in bright light to help you see the lice and nits (eggs). Use a tool, such as a comb or two unsharpened pencils to lift and part the hair. Look for tiny nits near the scalp, beginning at the back of the neck and behind the ears. Small sections of hair (1-2 inches wide) should be examined at a time. Unlike dandruff, nits stick to the hair. Dandruff should move when lightly touched. If either lice or nits (eggs) are found, treat with Creme Rinse. Treat Wash hair with a shampoo without conditioner. Do not use a shampoo that contain a conditioner or a conditioner alone since this may decrease the activity of Nix. Rinse with water. Towel dry hair so it is damp but not wet. Shake the bottle of Nix well. Completely saturate the hair and scalp with Nix. Begin to apply NIX behind the ears and at the back of the neck. Keep Nix out of the eyes. Protect the eyes with a washcloth or towel. Leave NIX on the hair for 10 minutes, but no longer. Rinse with warm water. Towel dry hair and comb out tangles. If live lice are seen seven days or more after the first treatment, a second treatment should be given. Remove Lice/Nits Remove nits by combing the hair with the special small tooth comb provided. Remaining nits may be removed by hand (using a throw-away glove), or cutting the nits out. Use the nit comb provided and make sure the hair remains slightly damp while removing nits. If the hair dries during combing, dampen it slightly with water. Part the hair into 4 sections. Work on one section at a time. Longer hair may take more time (1-2 hours). Start at the top of the head on the section you have picked. With one hand, lift a 1-2 inch wide strand of hair. Get the teeth of the comb as close to the scalp as possible and comb with a firm, even motion away from the scalp to the end of the hair. Use clips to pin back each strand of hair after you have combed out the nits. Clean the comb completely as you go. Wipe the nits from the comb with a tissue and throw away the tissue in a sealed plastic bag to prevent the lice from coming back. After combing, recheck the entire head for nits and repeat combing if necessary. Check the affected head daily to remove any nits that you might have missed.
Warnings from packaging: Important: Read all the directions in the Consumer Information Sheet and warnings before use. For external use only. Do not use: On children under 2 months of age Near the eyes Inside the nose, ear, mouth or vagina On lice in eyebrows or eyelashes. See your doctor.Ask a doctor before use if you are allergic to ragweed. May cause breathing difficulty or an asthmatic episode. When using this product: Keep eyes tightly closed and protect eyes with a washcloth or towel. If product gets into the eyes, immediately flush with large amounts of water. Scalp itching or redness may occur. It pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
| score | data gap | concerns | |
| METHYLPARABEN | 10 | 63% | Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes |
| FRAGRANCE | 8 | 100% | Neurotoxicity, Allergies/immunotoxicity, Miscellaneous |
| PROPYLPARABEN | 5 | 71% | Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive) |
| PERMETHRIN (Active Ingredient) | 4 | 75% | Cancer, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards |
| ISOPROPYL ALCOHOL | 4 | 72% | Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| FD&C YELLOW 6 | 1 | 70% | none identified |
| PROPYLENE GLYCOL | 4 | 60% | Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption |
| CETETH-10 POLYOXYETHYLENE 10 CETYL ETHER | 3 | 99% | Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE) |
| CITRIC ACID | 2 | 72% | Violations, restrictions & warnings |
| HYDROLYZED COLLAGEN HYDROLYZED ANIMAL PROTEIN | 0 | 88% | none identified |
| CETYL ALCOHOL | 1 | 87% | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| STEARALKONIUM CHLORIDE | 1 | 85% | none identified |
| HYDROXYETHYLCELLULOSE | 1 | 82% | none identified |
| ABIES BALSAMEA (BALSAM) BALSAM CANADA | 0 | 94% | none identified |
| WATER | 0 | 0% | innocuous |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more in vitro tests on mammalian cells show positive mutation results | PROPYLPARABEN, PROPYLENE GLYCOL, METHYLPARABEN | |
| Cancer - not classifiable/not likely to be human carcinogen | FD&C YELLOW 6, ISOPROPYL ALCOHOL, PERMETHRIN |
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show reproductive system effects at high doses | FD&C YELLOW 6, HYDROXYETHYLCELLULOSE, PERMETHRIN | |
| One or more animal studies show reproductive effects at moderate doses | PROPYLENE GLYCOL | |
| Limited evidence of developmental toxicity | ISOPROPYL ALCOHOL | |
| One or more animal studies show any effects at low doses | PROPYLPARABEN |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | PROPYLENE GLYCOL | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | CITRIC ACID | |
| Violation of government restrictions - Banned or found unsafe for use in cosmetics | METHYLPARABEN |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show brain and nervous system effects at high doses | PERMETHRIN, PROPYLENE GLYCOL, FD&C YELLOW 6 | |
| One or more animal studies show brain and nervous system effects at moderate doses | STEARALKONIUM CHLORIDE | |
| One or more animal studies show brain and nervous system effects at high doses | HYDROXYETHYLCELLULOSE | |
| One or more animal studies show brain and nervous system effects at moderate doses | METHYLPARABEN | |
| Moderate evidence of human neurotoxicity | FRAGRANCE | |
| Strong evidence of human neurotoxicity | ISOPROPYL ALCOHOL |
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Human any disruptor - moderate evidence | PERMETHRIN | |
| Human any disruptor - strong evidence | PROPYLPARABEN, METHYLPARABEN |
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Limited evidence of skin and immune system toxicity | PROPYLENE GLYCOL | |
| Limited evidence of immune system toxicity | products for use on skin | PERMETHRIN |
| Human skin toxicant - strong evidence | PROPYLPARABEN, METHYLPARABEN | |
| Known human immune system toxicant | FRAGRANCE |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show metabolic effects at high doses (low dose studies may be unavailable for this ingredient) | PROPYLENE GLYCOL, FD&C YELLOW 6, HYDROXYETHYLCELLULOSE, CETYL ALCOHOL | |
| One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient) | CITRIC ACID, STEARALKONIUM CHLORIDE | |
| Limited evidence of sense organ toxicity | ISOPROPYL ALCOHOL, PROPYLPARABEN, PERMETHRIN | |
| Known human any toxicant | METHYLPARABEN |
*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Occupational hazards related to handling | ISOPROPYL ALCOHOL | |
| Ingredient not fully labeled - identity unknown | FRAGRANCE |
*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not suspected to be an environmental toxin | ISOPROPYL ALCOHOL | |
| Suspected to be an environmental toxin | CETYL ALCOHOL | |
| Wildlife and environmental toxicity | PERMETHRIN, PROPYLPARABEN |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show skin irritation at moderate doses | PERMETHRIN, STEARALKONIUM CHLORIDE, CITRIC ACID | |
| One or more animal studies show skin irritation at low doses | METHYLPARABEN | |
| One or more animal studies show skin irritation at very low doses | CETYL ALCOHOL | |
| Classified as skin irritant | PROPYLENE GLYCOL, ISOPROPYL ALCOHOL |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Safety assessment was based on related chemical | PROPYLENE GLYCOL | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | STEARALKONIUM CHLORIDE | |
| Safety assessment was based on related chemical | CETETH-10, CETETH-10 | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | PROPYLPARABEN, METHYLPARABEN, HYDROLYZED COLLAGEN, HYDROXYETHYLCELLULOSE, CETETH-10, CETYL ALCOHOL | |
| Not assessed for safety in cosmetics by industry panel | PERMETHRIN, ISOPROPYL ALCOHOL, FRAGRANCE, CITRIC ACID, ABIES BALSAMEA (BALSAM) |
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to high doses | ISOPROPYL ALCOHOL | |
| Allowed workplace exposures restricted to low doses | PERMETHRIN |
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | PERMETHRIN, PROPYLENE GLYCOL | |
| Interferes with gene expresion | METHYLPARABEN | |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | CITRIC ACID |
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