Clarins Extra Firming Starter Collection || Skin Deep: Cosmetic Safety Reviews

CLARINS EXTRA FIRMING STARTER COLLECTION

last updated: 04/03/08 brand: Clarins by Clarins of Paris

SCORE

high hazard (out of 10)

82%

data gap

BUY ONLINE/BETTER PRODUCTS

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100% of anti-agings have lower concerns
100% of around-eye creams have lower concerns
100% of exfoliant/scrubs have lower concerns
100% of facial moisturizer/treatments have lower concerns
99% of masks have lower concerns

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company does not test on animals.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes

Ingredients from packaging: Water (Aqua), Caprylic/Capric Triglyceride, Glycerin, Corylus Avellana (Hazel) Seed Oil, Hydrolyzed Hazelnut Protein, Corylus Avellana (Hazel) Leaf Water, Propylene Glycol, Phenoxyethanol, Polyacrylamide, Butylene Glycol, Acrylates/C10-30 Alkyl Acraylate Crosspolymer, C13-14 Isoparaffin, Carbomer, Fragrance (Parfum), Triticum Vulgare (Wheat) Protein, Methylparaben, Sodium Hydroxide, Disodium EDTA, Psidium Guajava Fruit Extract, Triclosan, Laureth-7, Biosaccharide-Gum 1, Tocopherol, Butylparaben, Ethylparaben, Equisetum Arvense Extract, Spiraea Ulmaria Extract, Propylparaben, Isobutylparaben, Sequoiadendron Gigantea Stem Extract, Fomes Officinalis (Mushroom) Extract, Helianthus Annuus (Sunflower) Extract, Steareth-20, PEG-40 Hydrogenated Castor Oil, Potassium Sorbate, Arginine, Glycine, Sodium Dehydroacetate, Methionine, Tocopheryl Acetate, Limonene, Linalool, Yellow 6 (CI 15985)

Directions from packaging: -Apply serum before moisturizing, morning and evening after cleansing face.-Finish regimen by applying eye product to eye contour area.-Apply facial mask morning or evening to neck and face, including eye and lip contour area.-After ten minutes, remove product using a cotton pad soaked in water

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ingredients

	score	data gap	concerns
METHYLPARABEN	10	63%	Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes
ALUMINUM STARCH OCTENYLSUCCINATE ALUMINUM STARCH OCTENYLSUCCIANTE	9	74%	Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive), Contamination concerns (ARSENIC, LEAD, HEAVY METALS)
FRAGRANCE	8	100%	Neurotoxicity, Allergies/immunotoxicity, Miscellaneous
SILICA	1	69%	Biochemical or cellular level changes
PEG-100 STEARATE	4	69%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
TRICLOSAN	7	67%	Violations, restrictions & warnings, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (CHLOROFORM, DIOXIN)
BUTYLPARABEN	6	79%	Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
PEG-8	4	76%	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
PEG-40 HYDROGENATED CASTOR OIL	4	75%	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
LECITHIN	3	70%	Multiple, additive exposure sources, Enhanced skin absorption, Contamination concerns (NITROSAMINES)
LILIAL BUTYLPHENYL METHYLPROPIONAL	5	64%	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
METHYLCHLOROISOTHIAZOLINONE	6	63%	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
METHYLISOTHIAZOLINONE	6	63%	Violations, restrictions & warnings, Allergies/immunotoxicity
BENZYL SALICYLATE	6	62%	Violations, restrictions & warnings, Allergies/immunotoxicity
BHT	6	61%	Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards, Biochemical or cellular level changes
GERANIOL	6	61%	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
LIMONENE	6	56%	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
ETHYLPARABEN	5	80%	Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
PROPYLPARABEN	5	71%	Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
BENZOPHENONE-2	5	67%	Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
CITRONELLOL	5	65%	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
LINALOOL	5	65%	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
COCAMIDOPROPYL BETAINE	5	63%	Allergies/immunotoxicity, Contamination concerns (NITROSAMINES)
SODIUM LAURETH SULFATE	4	86%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
TITANIUM DIOXIDE (NON-NANO)	1	81%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards, Biochemical or cellular level changes
TOCOPHERYL ACETATE	4	81%	Allergies/immunotoxicity, Contamination concerns (HYDROQUINONE)
CAFFEINE	4	75%	Developmental/reproductive toxicity, Neurotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
MINERAL OIL	2	73%	Organ system toxicity (non-reproductive), Occupational hazards
SODIUM POLYACRYLATE	4	73%	Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Contamination concerns (METHACRYLIC ACID, ACRYLIC ACID, 2-ETHYLHEXYL ACRYLATE)
FD&C YELLOW 6 YELLOW 6 (CI 15985)	4	70%	Violations, restrictions & warnings
PHENOXYETHANOL	4	67%	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
PROPYLENE GLYCOL	4	60%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
LAURETH-7	3	100%	Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
ISOBUTYLPARABEN	3	83%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
SORBIC ACID	3	80%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
ARGININE	3	79%	Neurotoxicity, Organ system toxicity (non-reproductive)
DIETHYLHEXYL ADIPATE	3	78%	Cancer, Endocrine disruption, Organ system toxicity (non-reproductive)
DISODIUM EDTA	3	78%	Neurotoxicity, Organ system toxicity (non-reproductive), Enhanced skin absorption
SODIUM HYDROXIDE	3	77%	Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
DIMETHICONE	2	74%	Violations, restrictions & warnings
GLYCERYL MYRISTATE	3	74%	Violations, restrictions & warnings, Irritation (skin, eyes, or lungs), Enhanced skin absorption
POLYACRYLAMIDE	3	71%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Contamination concerns (ACRYLAMIDE)
TOCOPHEROL	2	87%	Contamination concerns (HYDROQUINONE)
CYCLOMETHICONE	2	83%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive)
TETRASODIUM EDTA	2	81%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards
DEXTRAN	2	80%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
SODIUM DEHYDROACETATE	2	78%	Occupational hazards
CAMELLIA SINENSIS (GREEN TEA) LEAF EXTRACT CAMELLIA SINENSIS LEAF EXTRACT	2	76%	Violations, restrictions & warnings
GLYCERIN	2	74%	Organ system toxicity (non-reproductive), Occupational hazards
CHLORPHENESIN	2	72%	Violations, restrictions & warnings
SODIUM PCA	2	71%	Contamination concerns (NITROSAMINES)
ROSA CENTIFOLIA (CABBAGE ROSE) FLOWER EXTRACT ROSA CENTIFOLIA FLOWER EXTRACT	1	97%	Irritation (skin, eyes, or lungs)
HYDROLYZED WHEAT PROTEIN	1	95%	Allergies/immunotoxicity
CAPRYLIC/ CAPRIC TRIGLYCERIDE	0	94%	none identified
C13-14 ISOPARAFFIN	1	93%	none identified
CETEARYL ALCOHOL	0	93%	none identified
GLYCOL DISTEARATE	1	93%	Multiple, additive exposure sources
SQUALANE	1	93%	Irritation (skin, eyes, or lungs)
PANAX GINSENG (GINSENG) ROOT EXTRACT PANAX GINSENG ROOT EXTRACT	1	91%	none identified
ETHYLHEXYLGLYCERIN	1	90%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
TRITICUM VULGARE (WHEAT) GERM OIL	1	90%	none identified
GLYCERYL MONOSTEARATE GLYCERYL STEARATE	1	88%	none identified
PHENOXYISOPROPANOL	1	88%	none identified
STEARETH-20	1	88%	none identified
CETYL ALCOHOL	1	87%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
OCTYLDODECANOL	1	87%	Irritation (skin, eyes, or lungs)
POTASSIUM SORBATE	1	85%	none identified
DIPROPYLENE GLYCOL	1	84%	Irritation (skin, eyes, or lungs)
STEARYL ALCOHOL	1	84%	Irritation (skin, eyes, or lungs)
METHIONINE	1	82%	none identified
BISABOLOL	1	80%	Enhanced skin absorption
CELLULOSE GUM	1	80%	none identified
BUTYLENE GLYCOL	1	79%	Irritation (skin, eyes, or lungs)
GLYCINE	1	79%	none identified
ACRYLATES/ C10-30 ALKYL ACRYLATE CROSSPOLYMER ACRYLATES/C10-30 ALKYL ACRAYLATE CROSSPOLYMER	0	100%	none identified
AGRIMONIA EUPATORIA (AGRIMONY) LEAF EXTRACT AGRIMONIA EUPATORIA LEAF EXTRACT	0	100%	none identified
BIOSACCHARIDE GUM BIOSACCARIDE GUM-4	0	100%	none identified
BUTYROSPERMUM PARKII (SHEA BUTTER) FRUIT	0	100%	none identified
CETEARYL GLUCOSIDE	0	100%	none identified
EQUISETUM ARVENSE (HORSETAIL) EXTRACT EQUISETUM ARVENSE EXTRACT	0	100%	none identified
HYDROGENATED COCO-GLYCERIDES	0	100%	none identified
ISONONYL ISONONANOATE	0	100%	none identified
LINUM USITATISSIMUM (FLAX) SEED EXTRACT LINUM USITATISSIMUM (LINSEED) SEED EXTRACT	0	100%	none identified
MORINGA PTERYGOSPERMA (MORINGA OLEIFERA) SEED EXTRACT MORINGA PTERYGOSPERMA SEED EXTRACT	0	100%	none identified
MUSHROOM EXTRACT	0	100%	none identified
POTASSIUM CETYL PHOSPHATE	0	100%	none identified
PSIDIUM GUAJAVA (GUAVA) FRUIT EXTRACT PSIDIUM GUAJAVA FRUIT EXTRACT	0	100%	none identified
SILOXANETRIOL ALGINATE	0	100%	none identified
SPIRAEA ULMARIA (MEADOWSWEET) EXTRACT SPIRAEA ULMARIA EXTRACT	0	100%	none identified
TEA COCOYL GLUTAMATE	0	100%	none identified
TRITICUM VULGARE (WHEAT) PROTEIN	0	100%	none identified
ACETYL TETRAPEPTIDE-2	0	100%	none identified
BIOSACCHARIDE GUM-1	0	100%	none identified
CITRUS AURANTIUM DULCIS (ORANGE) FRUIT WATER	0	100%	none identified
CORYLUS AVELLANA (HAZEL) LEAF WATER	0	100%	none identified
HELIANTHUS ANNUUS (SUNFLOWER) EXTRACT	0	100%	none identified
HIBISCUS ESCULENTUS SEED EXTRACT	0	100%	none identified
HYDROLYZED HAZELNUT PROTEIN	0	100%	none identified
PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) FRUIT EXTRACT	0	100%	none identified
SEQUOIADENDRON GIGANTEA STEM EXTRACT	0	100%	none identified
GLYCERYL ACRYLATE/ACRYLIC ACID COPOLYMER	0	100%	none identified
LAPSANA COMMUNIS EXTRACT	0	100%	none identified
EUGLENA GRACILIS EXTRACT	0	100%	none identified
CETEARYL ETHYLHEXANOATE	0	99%	none identified
CORYLUS AVELLANA (HAZEL) SEED OIL	0	99%	none identified
CAPRYLYL GLYCOL	0	94%	none identified
HELIANTHUS ANNUUS (SUNFLOWER) OIL HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL	0	94%	none identified
HUMULUS LUPULUS (HOPS) EXTRACT	0	94%	none identified
HYDROLYZED GLYCINE SOJA (SOY) PROTEIN HYDROLYZED SOY PROTEIN	0	94%	none identified
LAURAMIDE MIPA	0	94%	none identified
XANTHAN GUM	0	94%	none identified
ALTHAEA OFFICINALIS ROOT EXTRACT	0	94%	none identified
CARBOMER	0	93%	none identified
CELLULOSE	0	0%	innocuous
SODIUM CHLORIDE	0	0%	innocuous
WATER	0	0%	innocuous

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show tumor formation at high doses		MINERAL OIL, STEARYL ALCOHOL
One or more in vitro tests non-mammalian cells show positive mutation results		TRITICUM VULGARE (WHEAT) GERM OIL
One or more animal studies show tumor formation at high doses		CELLULOSE GUM, DEXTRAN
One or more in vitro tests non-mammalian cells show positive mutation results		METHYLCHLOROISOTHIAZOLINONE, PHENOXYETHANOL, TRICLOSAN
One or more in vitro tests on mammalian cells show positive mutation results		TOCOPHERYL ACETATE
One or more animal studies show tumor formation at moderate doses		PEG-100 STEARATE
One or more in vitro tests non-mammalian cells show positive mutation results		LINALOOL
One or more in vitro tests on mammalian cells show positive mutation results		TOCOPHEROL, TITANIUM DIOXIDE (NON-NANO), SORBIC ACID, SODIUM HYDROXIDE, SODIUM DEHYDROACETATE, SODIUM CHLORIDE, PROPYLPARABEN, PROPYLENE GLYCOL, POTASSIUM SORBATE, METHYLPARABEN, GLYCINE, GLYCERIN, GERANIOL, ETHYLPARABEN, DISODIUM EDTA, BUTYLPARABEN, BENZOPHENONE-2, ARGININE
Cancer - not classifiable/not likely to be human carcinogen		FD&C YELLOW 6, LIMONENE, CAFFEINE, BHT
Limited evidence of carcinogenicity		DIETHYLHEXYL ADIPATE

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive system effects at high doses		FD&C YELLOW 6, ETHYLPARABEN, METHIONINE, PHENOXYISOPROPANOL, SODIUM DEHYDROACETATE, TRICLOSAN, PEG-100 STEARATE, DIETHYLHEXYL ADIPATE, DISODIUM EDTA, BHT, BUTYLENE GLYCOL, LILIAL, DEXTRAN,
One or more animal studies show developmental effects at high doses		LIMONENE
One or more animal studies show reproductive effects at moderate doses		PROPYLENE GLYCOL
One or more animal studies show reproductive effects at low doses		CAFFEINE
One or more animal studies show reproductive effects at moderate doses		ARGININE
Human nervous system toxicant - moderate evidence		ALUMINUM STARCH OCTENYLSUCCINATE
One or more animal studies show reproductive effects at moderate doses		CELLULOSE GUM, GLYCERIN
One or more animal studies show any effects at very low doses		BUTYLPARABEN
One or more animal studies show any effects at low doses		PROPYLPARABEN

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		PEG-100 STEARATE, SODIUM POLYACRYLATE, SODIUM PCA, PROPYLENE GLYCOL, POLYACRYLAMIDE, PEG-8, PEG-40 HYDROGENATED CASTOR OIL, METHYLISOTHIAZOLINONE, METHYLCHLOROISOTHIAZOLINONE, LECITHIN, COCAMIDOPROPYL BETAINE, ALUMINUM STARCH OCTENYLSUCCINATE
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel		GLYCERYL MYRISTATE, DIMETHICONE, GERANIOL, CITRONELLOL, CAMELLIA SINENSIS (GREEN TEA) LEAF EXTRACT, LILIAL, BENZYL SALICYLATE, LINALOOL, LIMONENE
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		TRICLOSAN, METHYLISOTHIAZOLINONE, METHYLCHLOROISOTHIAZOLINONE, CHLORPHENESIN, TRICLOSAN, PHENOXYETHANOL, METHYLCHLOROISOTHIAZOLINONE, CHLORPHENESIN, METHYLISOTHIAZOLINONE, METHYLCHLOROISOTHIAZOLINONE
Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Color additive not approved by FDA for cosmetics used around eyes	products for use around the eyes	FD&C YELLOW 6
Violation of government restrictions - Banned or found unsafe for use in cosmetics		METHYLPARABEN

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show brain and nervous system effects at high doses		GLYCERIN, GLYCINE, POLYACRYLAMIDE, POTASSIUM SORBATE, PROPYLENE GLYCOL, SODIUM DEHYDROACETATE
One or more in vitro tests on mammalian cells demonstrate neurotoxicity		METHYLISOTHIAZOLINONE
One or more animal studies show brain and nervous system effects at high doses		FD&C YELLOW 6, DIPROPYLENE GLYCOL, BUTYLENE GLYCOL, DEXTRAN
One or more animal studies show brain and nervous system effects at moderate doses		PHENOXYETHANOL, METHYLPARABEN, LINALOOL, LECITHIN, GERANIOL, CITRONELLOL, CHLORPHENESIN, LILIAL, BISABOLOL
One or more animal studies show brain and nervous system effects at low doses		DISODIUM EDTA, BHT
One or more animal studies show brain and nervous system effects at very low doses		SODIUM HYDROXIDE, CAFFEINE, ARGININE
Moderate evidence of human neurotoxicity		FRAGRANCE
Strong evidence of human neurotoxicity		ALUMINUM STARCH OCTENYLSUCCINATE

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Associated with endocrine disruption		LILIAL, BENZYL SALICYLATE
One or more animal studies show endocrine system disruption at high doses		SODIUM PCA, METHIONINE, GLYCINE, GLYCERIN, DISODIUM EDTA, CAFFEINE, BUTYLENE GLYCOL, BISABOLOL, BHT
One or more animal studies show endocrine disruption at moderate doses		ISOBUTYLPARABEN, ARGININE
Human any disruptor - strong evidence		METHYLPARABEN, PROPYLPARABEN
One or more studies show endocrine disruption at very low doses		TRICLOSAN
Limited evidence of endocrine disruption		DIETHYLHEXYL ADIPATE
Human any disruptor - strong evidence		ETHYLPARABEN, BUTYLPARABEN, BENZOPHENONE-2

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Limited evidence of skin and immune system toxicity		PHENOXYETHANOL
One or more human case studies show possible skin allergy effects		HYDROLYZED WHEAT PROTEIN
One or more animal studies show immune effects at low doses		TITANIUM DIOXIDE (NON-NANO)
Limited evidence of skin and immune system toxicity		PROPYLENE GLYCOL
Human skin toxicant - strong evidence		TOCOPHERYL ACETATE, SORBIC ACID, PROPYLPARABEN, METHYLPARABEN, ISOBUTYLPARABEN
Possible human immune system toxicant		LINALOOL
Human skin toxicant - strong evidence		BENZOPHENONE-2, BUTYLPARABEN, ETHYLPARABEN
Possible human immune system toxicant		LILIAL, CITRONELLOL
Known human immune system toxicant		METHYLISOTHIAZOLINONE, METHYLCHLOROISOTHIAZOLINONE, GERANIOL, LIMONENE, FRAGRANCE, BHT, COCAMIDOPROPYL BETAINE, BENZYL SALICYLATE

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not suspected to be bioaccumulative		SODIUM POLYACRYLATE, TITANIUM DIOXIDE (NON-NANO), SODIUM HYDROXIDE, POLYACRYLAMIDE
Not suspected to be persistent		DIETHYLHEXYL ADIPATE, CETYL ALCOHOL
Persistent, bioaccumulative in wildlife		TRICLOSAN, CYCLOMETHICONE, CAFFEINE

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient)		PANAX GINSENG (GINSENG) ROOT EXTRACT, BISABOLOL, FD&C YELLOW 6, SODIUM PCA, PHENOXYISOPROPANOL, GLYCINE, LIMONENE, CELLULOSE GUM, BENZYL SALICYLATE
One or more animal studies show sense organ effects at moderate doses (low dose studies may be unavailable for this ingredient)	products for use around the eyes, mouth, or lips	TRITICUM VULGARE (WHEAT) GERM OIL, STEARYL ALCOHOL, SILICA, PROPYLENE GLYCOL, OCTYLDODECANOL, DIPROPYLENE GLYCOL, CYCLOMETHICONE, CETYL ALCOHOL, BUTYLENE GLYCOL
One or more animal studies show liver effects at moderate doses (low dose studies may be unavailable for this ingredient)		POLYACRYLAMIDE, STEARETH-20, TOCOPHERYL ACETATE, SODIUM DEHYDROACETATE, POTASSIUM SORBATE, METHIONINE, GLYCERYL MONOSTEARATE,
One or more animal studies show any effects at moderate doses (low dose studies may be unavailable for this ingredient)		C13-14 ISOPARAFFIN
Limited evidence of sense organ toxicity		PEG-100 STEARATE, SORBIC ACID, PROPYLPARABEN, PEG-8, PEG-40 HYDROGENATED CASTOR OIL, ALUMINUM STARCH OCTENYLSUCCINATE, ISOBUTYLPARABEN, ETHYLPARABEN, BUTYLPARABEN
One or more animal studies show sense organ effects at low doses	products for use around the eyes, mouth, or lips	SODIUM POLYACRYLATE, SODIUM CHLORIDE, MINERAL OIL, LINALOOL
One or more animal studies show kidney or renal system effects at very low doses		GLYCERIN, SODIUM HYDROXIDE,
One or more animal studies show sense organ effects at very low doses	products for use around the eyes, mouth, or lips	PHENOXYETHANOL
One or more animal studies show sense organ effects at low doses	products for use around the eyes, mouth, or lips	CITRONELLOL, BENZOPHENONE-2
One or more animal studies show classified as toxic effects at low doses		DIETHYLHEXYL ADIPATE
One or more animal studies show broad systemic effects at low doses		TRICLOSAN, GERANIOL, DISODIUM EDTA, BHT
One or more animal studies show sense organ effects at very low doses	products for use around the eyes, mouth, or lips	SODIUM LAURETH SULFATE
One or more animal studies show cardiovascular effects at very low doses		TITANIUM DIOXIDE (NON-NANO), DEXTRAN, CAFFEINE, ARGININE
Possible human immune system toxicant		METHYLCHLOROISOTHIAZOLINONE
Limited evidence of eye toxicity	products for use around the eyes	TETRASODIUM EDTA, ETHYLHEXYLGLYCERIN
Known human any toxicant		METHYLPARABEN

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Occupational hazards related to handling		SODIUM HYDROXIDE, LIMONENE
Ingredient not fully labeled - identity unknown		FRAGRANCE

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Designated as safe for general or specific, limited use in food		XANTHAN GUM, PEG-100 STEARATE, SORBIC ACID, STEARYL ALCOHOL, TETRASODIUM EDTA, TITANIUM DIOXIDE (NON-NANO), TOCOPHEROL, TOCOPHERYL ACETATE, SODIUM POLYACRYLATE, SODIUM HYDROXIDE, SODIUM DEHYDROACETATE, SODIUM CHLORIDE, PSIDIUM GUAJAVA (GUAVA) FRUIT EXTRACT, PROPYLPARABEN, PROPYLENE GLYCOL, POTASSIUM SORBATE, POLYACRYLAMIDE, PEG-8, PEG-40 HYDROGENATED CASTOR OIL, MINERAL OIL, METHYLPARABEN, METHIONINE, LINALOOL, LECITHIN, HUMULUS LUPULUS (HOPS) EXTRACT, GLYCINE, GLYCERYL MONOSTEARATE, GLYCERIN, GERANIOL, FD&C YELLOW 6, DISODIUM EDTA, LIMONENE, DIMETHICONE, DEXTRAN, CITRONELLOL, CETYL ALCOHOL, CELLULOSE GUM, CAMELLIA SINENSIS (GREEN TEA) LEAF EXTRACT, CAFFEINE, BUTYLPARABEN, BUTYLENE GLYCOL, BHT, BENZYL SALICYLATE, ARGININE, ALUMINUM STARCH OCTENYLSUCCINATE
Used in food or as an additive with limited or no toxicity information available		SODIUM POLYACRYLATE, LECITHIN, GLYCOL DISTEARATE

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Wildlife and environmental toxicity		PROPYLPARABEN
Suspected to be an environmental toxin		POLYACRYLAMIDE, CYCLOMETHICONE, CETYL ALCOHOL
Not suspected to be an environmental toxin		TITANIUM DIOXIDE (NON-NANO), SODIUM POLYACRYLATE, SODIUM HYDROXIDE
Wildlife and environmental toxicity		TRICLOSAN, LIMONENE, DIETHYLHEXYL ADIPATE

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show skin irritation at very low doses		SORBIC ACID, PEG-100 STEARATE, SODIUM HYDROXIDE, CETYL ALCOHOL, CITRONELLOL, DEXTRAN, GERANIOL, LINALOOL
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	STEARYL ALCOHOL, OCTYLDODECANOL, SODIUM LAURETH SULFATE, DIPROPYLENE GLYCOL, GLYCERYL MYRISTATE
Classified as skin irritant		PROPYLENE GLYCOL
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	BUTYLENE GLYCOL
Classified as irritant		LIMONENE, ETHYLHEXYLGLYCERIN, PHENOXYETHANOL, TRICLOSAN
One or more animal studies show skin irritation at moderate doses		TITANIUM DIOXIDE (NON-NANO), TRITICUM VULGARE (WHEAT) GERM OIL, GLYCERIN, MINERAL OIL, SODIUM CHLORIDE
One or more animal studies show skin irritation at low doses		TETRASODIUM EDTA
One or more animal studies show skin irritation at moderate doses		BISABOLOL, BUTYLPARABEN, CAFFEINE, CYCLOMETHICONE
One or more animal studies show skin irritation at low doses		ROSA CENTIFOLIA (CABBAGE ROSE) FLOWER EXTRACT, SQUALANE, METHYLPARABEN, LILIAL, BHT

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		SODIUM DEHYDROACETATE
Safety assessment was based on related chemical		STEARETH-20, PROPYLENE GLYCOL, PEG-100 STEARATE, ISOBUTYLPARABEN, GLYCERYL MYRISTATE
Insufficient data to determine safety		CORYLUS AVELLANA (HAZEL) SEED OIL
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		DIETHYLHEXYL ADIPATE, DIMETHICONE, DIPROPYLENE GLYCOL, DISODIUM EDTA, ETHYLPARABEN, GLYCERYL MONOSTEARATE, TETRASODIUM EDTA, TOCOPHEROL, TOCOPHERYL ACETATE
Considered safe based on assumption of low absorption		POLYACRYLAMIDE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		STEARETH-20, PEG-100 STEARATE
Considered safe based on assumption of low absorption		SODIUM POLYACRYLATE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		TRITICUM VULGARE (WHEAT) GERM OIL, STEARYL ALCOHOL, SORBIC ACID, SODIUM LAURETH SULFATE, CETEARYL ETHYLHEXANOATE, CETYL ALCOHOL, PROPYLPARABEN, POTASSIUM SORBATE, METHYLPARABEN, OCTYLDODECANOL, PHENOXYETHANOL, GLYCERYL MYRISTATE, GLYCOL DISTEARATE, CYCLOMETHICONE, CETEARYL ALCOHOL, BUTYLPARABEN, CARBOMER, CELLULOSE GUM, BUTYLENE GLYCOL, BISABOLOL
Not assessed for safety in cosmetics by industry panel		EUGLENA GRACILIS EXTRACT
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		BENZOPHENONE-2, BHT
Not assessed for safety in cosmetics by industry panel		HIBISCUS ESCULENTUS SEED EXTRACT, HYDROLYZED HAZELNUT PROTEIN, PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) FRUIT EXTRACT, SEQUOIADENDRON GIGANTEA STEM EXTRACT, GLYCERYL ACRYLATE/ACRYLIC ACID COPOLYMER, LAPSANA COMMUNIS EXTRACT, ALTHAEA OFFICINALIS ROOT EXTRACT, BIOSACCHARIDE GUM-1, CITRUS AURANTIUM DULCIS (ORANGE) FRUIT WATER, CORYLUS AVELLANA (HAZEL) LEAF WATER, HELIANTHUS ANNUUS (SUNFLOWER) EXTRACT, MUSHROOM EXTRACT, PANAX GINSENG (GINSENG) ROOT EXTRACT, PHENOXYISOPROPANOL, POTASSIUM CETYL PHOSPHATE, PSIDIUM GUAJAVA (GUAVA) FRUIT EXTRACT, ROSA CENTIFOLIA (CABBAGE ROSE) FLOWER EXTRACT, SILOXANETRIOL ALGINATE, SODIUM HYDROXIDE, SPIRAEA ULMARIA (MEADOWSWEET) EXTRACT, SQUALANE, TEA COCOYL GLUTAMATE, TITANIUM DIOXIDE (NON-NANO), TRICLOSAN, TRITICUM VULGARE (WHEAT) PROTEIN, XANTHAN GUM, ACETYL TETRAPEPTIDE-2, HUMULUS LUPULUS (HOPS) EXTRACT, HYDROGENATED COCO-GLYCERIDES, HYDROLYZED GLYCINE SOJA (SOY) PROTEIN, HYDROLYZED WHEAT PROTEIN, ISONONYL ISONONANOATE, LAURAMIDE MIPA, LAURETH-7, LINALOOL, LINUM USITATISSIMUM (FLAX) SEED EXTRACT, METHIONINE, MINERAL OIL, MORINGA PTERYGOSPERMA (MORINGA OLEIFERA) SEED EXTRACT, ETHYLHEXYLGLYCERIN, FRAGRANCE, GERANIOL, GLYCERIN, GLYCINE, HELIANTHUS ANNUUS (SUNFLOWER) OIL, BENZYL SALICYLATE, BIOSACCHARIDE GUM, LILIAL, BUTYROSPERMUM PARKII (SHEA BUTTER) FRUIT, C13-14 ISOPARAFFIN, CAFFEINE, CAMELLIA SINENSIS (GREEN TEA) LEAF EXTRACT, CAPRYLIC/ CAPRIC TRIGLYCERIDE, CAPRYLYL GLYCOL, CETEARYL GLUCOSIDE, CHLORPHENESIN, CITRONELLOL, DEXTRAN, LIMONENE, EQUISETUM ARVENSE (HORSETAIL) EXTRACT, ACRYLATES/ C10-30 ALKYL ACRYLATE CROSSPOLYMER, AGRIMONIA EUPATORIA (AGRIMONY) LEAF EXTRACT, ARGININE

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to moderate doses		MINERAL OIL
No workplace limits set		SODIUM HYDROXIDE
Allowed workplace exposures restricted to moderate doses		GLYCERIN, CELLULOSE
Allowed workplace exposures restricted to low doses		BHT,
Allowed workplace exposures restricted to low doses		TETRASODIUM EDTA, SODIUM DEHYDROACETATE, PHENOXYETHANOL, TITANIUM DIOXIDE (NON-NANO)

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Interferes with gene expresion		METHYLPARABEN
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		PANAX GINSENG (GINSENG) ROOT EXTRACT, POLYACRYLAMIDE, PROPYLENE GLYCOL
Interferes with gene expresion		BUTYLPARABEN
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		CYCLOMETHICONE, DIETHYLHEXYL ADIPATE, GLYCERIN, GLYCINE
One or more animal studies show biochemical changes at low doses where the human health implications are not yet well understood		BHT
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		ARGININE, BENZOPHENONE-2, CELLULOSE GUM
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood		TITANIUM DIOXIDE (NON-NANO), SILICA, CAFFEINE