Clairol Herbal Essences 25 Beige Shimmer Medium Iridescent Blonde Hair Color by Clairol || Skin Deep: Cosmetic Safety Reviews

CLAIROL HERBAL ESSENCES 25 BEIGE SHIMMER MEDIUM IRIDESCENT BLONDE HAIR COLOR BY CLAIROL

last updated: 04/03/08 brand: Clairol by Procter & Gamble

SCORE

high hazard (out of 10)

81%

data gap

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99% of hair color and bleachings have lower concerns

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company conducts animal tests.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards

Ingredients from packaging: Permanent Color Gel: Water, Propylene Glycol, Ethanolamine, Hexylene Glycol, Soytrimonium Chloride, Ethoxydiglycol, C11-15 Pareth-9, Dilinoleic Acid, Fragrance, Cocamidopropyl Betaine, Oleic Acid, Ascorbic Acid, Aloe Barbadensis Flower Extract, Achillea Millefolium Extract, Anthemis Nobilis Flower Extract, Lonicera Japonica (Honeysuckle) Flower Extract, Bellis Perennis (Daisy) Flower Extract, Helianthus Annuus (Sunflower) Extract, Hydrolyzed Vegetable Protein, Oleamide MIPA, PEG-150/Stearyl/SMDI Copolymer, C12-15 Pareth-3, Oleth-2, Oleth-10, Sodium Sulfite, EDTA, Resorcinol, P-Phenylenediamine, P-Aminophenol, 4-Amino-2-Hydroxtoluene, N,N-BIS(2-Hydroxyethyl)-P-Phenylenediamine Sulfate, 1-Naphthol. Color Developing Creme: Water, Hydrogen Peroxide, Glyceryl Stearate, Cetearyl Alcohol, Emulsifying Wax, Stearamidopropyl Dimethylamine, PEG-75 Lanolin, Ceteareth-20, Oleth-10, Oleth-2, Etidronic Acid, Simethicone. Color Seal Conditioner: Water, Cetearyl Alcohol, Behentrimonium Chloride, Cyclomethicone, Trimethylsilylamodimethicone, Oleyl Alcohol, Sodium Cocoamphopropionate, Panthenol, Thymus Vulgaris (Thyme) Extract, Triticum Vulgare (Wheat) Germ Oil, Tocopherol, Fragrance, Citric Acid, Disodium EDTA, Propylene Glycol, DMDM Hydantoin, Iodopropynyl Butylcarbamate.

Warnings from packaging: This product contains ingredients which may cause skin irritation on certain individuals and a preliminary test according to accompanying directions should first be made. This product must not be used for dyeing the eyelashes or eyebrows; to do so may cause blindness.

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ingredients

	score	data gap	concerns
P-PHENYLENEDIAMINE	10	52%	Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
RESORCINOL	10	52%	Cancer, Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
DMDM HYDANTOIN	7	71%	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Contamination concerns (FORMALDEHYDE)
P-AMINOPHENOL	8	57%	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards
FRAGRANCE	8	100%	Neurotoxicity, Allergies/immunotoxicity, Miscellaneous
CETEARETH-20	5	71%	Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
1-NAPHTHOL	8	60%	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
ETHANOLAMINE	7	66%	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
PEG-150/ STEARYL ALCOHOL/ SMDI COPOLYMER PEG-150/STEARYL/SMDI COPOLYMER	4	76%	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
PEG-75 LANOLIN	4	75%	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
HYDROGEN PEROXIDE	3	65%	Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
IODOPROPYNYL BUTYLCARBAMATE	4	65%	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
4-AMINO-2-HYDROXYTOLUENE 4-AMINO-2-HYDROXTOLUENE	5	67%	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity
HEXYLENE GLYCOL	4	67%	Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
COCAMIDOPROPYL BETAINE	5	63%	Allergies/immunotoxicity, Contamination concerns (NITROSAMINES)
OLETH-10	3	87%	Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
OLETH-2	3	87%	Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
PROPYLENE GLYCOL	4	60%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
ACHILLEA MILLEFOLIUM (COMMON YARROW) EXTRACT ACHILLEA MILLEFOLIUM EXTRACT	3	89%	Allergies/immunotoxicity, Multiple, additive exposure sources
SODIUM SULFITE	3	87%	Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
DISODIUM EDTA	3	78%	Neurotoxicity, Organ system toxicity (non-reproductive), Enhanced skin absorption
EDTA	3	78%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
CITRIC ACID	2	72%	Violations, restrictions & warnings
N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE	3	69%	Cancer, Allergies/immunotoxicity
PANTHENOL	2	88%	Multiple, additive exposure sources
TOCOPHEROL	2	87%	Contamination concerns (HYDROQUINONE)
CYCLOMETHICONE	2	83%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive)
ETHOXYDIGLYCOL	2	82%	Organ system toxicity (non-reproductive)
OLEIC ACID	1	82%	Irritation (skin, eyes, or lungs)
ETIDRONIC ACID	2	79%	Endocrine disruption, Organ system toxicity (non-reproductive)
THYMUS VULGARIS (COMMON THYME) EXTRACT THYMUS VULGARIS (THYME) EXTRACT	1	100%	Multiple, additive exposure sources
BEHENTRIMONIUM CHLORIDE	0	94%	none identified
DILINOLEIC ACID	0	94%	none identified
OLEAMIDE MIPA	0	94%	none identified
STEARAMIDOPROPYL DIMETHYLAMINE	0	94%	none identified
SOYTRIMONIUM CHLORIDE	0	94%	none identified
CETEARYL ALCOHOL	0	93%	none identified
ASCORBIC ACID (VITAMIN C)	1	91%	none identified
TRITICUM VULGARE (WHEAT) GERM OIL	1	90%	none identified
GLYCERYL MONOSTEARATE GLYCERYL STEARATE	1	88%	none identified
C11-15 PARETH-9	1	88%	none identified
OLEYL ALCOHOL	1	87%	Irritation (skin, eyes, or lungs)
C12-15 PARETH-3	1	86%	Organ system toxicity (non-reproductive)
ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT ANTHEMIS NOBILIS FLOWER EXTRACT	1	80%	Enhanced skin absorption
ALOE BARBADENSIS (ALOE VERA) FLOWER EXTRACT ALOE BARBADENSIS FLOWER EXTRACT	1	73%	none identified
BELLIS PERENNIS (DAISY) FLOWER EXTRACT	0	100%	none identified
EMULSIFYING WAX	0	100%	none identified
HYDROLYZED VEGETABLE PROTEIN	0	100%	none identified
SIMETHICONE	0	100%	none identified
TRIMETHYLSILYLAMODIMETHICONE	0	100%	none identified
HELIANTHUS ANNUUS (SUNFLOWER) EXTRACT	0	100%	none identified
KINGINKA EKISU LONICERA JAPONICA (HONEYSUCKLE) FLOWER EXTRACT	0	100%	none identified
SODIUM COCOAMPHOPROPIONATE	0	99%	none identified
WATER	0	0%	innocuous

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more in vitro tests non-mammalian cells show positive mutation results		TRITICUM VULGARE (WHEAT) GERM OIL, ETHOXYDIGLYCOL
One or more in vitro tests on mammalian cells show positive mutation results		TOCOPHEROL, SODIUM SULFITE, PROPYLENE GLYCOL, OLEIC ACID, ETHANOLAMINE, EDTA, DISODIUM EDTA, ASCORBIC ACID (VITAMIN C)
Cancer - limited evidence		N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE, 4-AMINO-2-HYDROXYTOLUENE, 1-NAPHTHOL
Mutagen - limited evidence		P-AMINOPHENOL
Cancer - not classifiable/not likely to be human carcinogen		RESORCINOL, P-PHENYLENEDIAMINE, HYDROGEN PEROXIDE

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive effects at high doses		ETHOXYDIGLYCOL, EDTA, ETHANOLAMINE, DISODIUM EDTA
One or more animal studies show reproductive effects at moderate doses		PROPYLENE GLYCOL, P-AMINOPHENOL, ETIDRONIC ACID, 1-NAPHTHOL,
One or more animal studies show any effects at moderate doses		ALOE BARBADENSIS (ALOE VERA) FLOWER EXTRACT
Human nervous system toxicant - moderate evidence		P-PHENYLENEDIAMINE

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		PEG-150/ STEARYL ALCOHOL/ SMDI COPOLYMER, PEG-75 LANOLIN, PROPYLENE GLYCOL, IODOPROPYNYL BUTYLCARBAMATE, COCAMIDOPROPYL BETAINE, ETHANOLAMINE, CETEARETH-20, ALOE BARBADENSIS (ALOE VERA) FLOWER EXTRACT, RESORCINOL, P-AMINOPHENOL, P-PHENYLENEDIAMINE, N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE, 4-AMINO-2-HYDROXYTOLUENE, 1-NAPHTHOL
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel		P-PHENYLENEDIAMINE, 1-NAPHTHOL, 4-AMINO-2-HYDROXYTOLUENE, P-AMINOPHENOL
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		CITRIC ACID, P-PHENYLENEDIAMINE, IODOPROPYNYL BUTYLCARBAMATE, DMDM HYDANTOIN, RESORCINOL, IODOPROPYNYL BUTYLCARBAMATE, DMDM HYDANTOIN
Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Unsafe in products left on skin and not rinsed off	products that are intended to be left on the skin	ETHANOLAMINE

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study		HEXYLENE GLYCOL
One or more animal studies show brain and nervous system effects at moderate doses		OLEIC ACID
One or more animal studies show brain and nervous system effects at high doses		C12-15 PARETH-3, 4-AMINO-2-HYDROXYTOLUENE, ETHOXYDIGLYCOL, PROPYLENE GLYCOL
One or more animal studies show brain and nervous system effects at moderate doses		P-AMINOPHENOL, RESORCINOL
One or more animal studies show brain and nervous system effects at high doses		1-NAPHTHOL
One or more animal studies show brain and nervous system effects at moderate doses		CETEARETH-20, EDTA, ETHANOLAMINE, ETIDRONIC ACID, ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT
One or more animal studies show brain and nervous system effects at low doses		SODIUM SULFITE, DISODIUM EDTA
One or more animal studies show brain and nervous system effects at very low doses		HYDROGEN PEROXIDE
Moderate evidence of human neurotoxicity		FRAGRANCE
Strong evidence of human neurotoxicity		P-PHENYLENEDIAMINE

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show endocrine system disruption at high doses		P-PHENYLENEDIAMINE, N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE, HYDROGEN PEROXIDE, HEXYLENE GLYCOL, DISODIUM EDTA, ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT, 4-AMINO-2-HYDROXYTOLUENE
One or more animal studies show endocrine disruption at moderate doses		1-NAPHTHOL
One or more studies show endocrine system disruption at low doses		ETIDRONIC ACID
Human any disruptor - strong evidence		RESORCINOL

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Human immune system toxicant - moderate evidence		SODIUM SULFITE
Limited evidence of skin and immune system toxicity		PROPYLENE GLYCOL
Human skin toxicant - strong evidence		N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE, ETHANOLAMINE, ACHILLEA MILLEFOLIUM (COMMON YARROW) EXTRACT, 4-AMINO-2-HYDROXYTOLUENE, 1-NAPHTHOL, IODOPROPYNYL BUTYLCARBAMATE
Known human immune system toxicant		RESORCINOL, P-PHENYLENEDIAMINE, P-AMINOPHENOL, DMDM HYDANTOIN, HEXYLENE GLYCOL, FRAGRANCE, COCAMIDOPROPYL BETAINE

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Persistent, bioaccumulative in wildlife		CYCLOMETHICONE
Not suspected to be persistent		C12-15 PARETH-3
Not suspected to be bioaccumulative		EDTA

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show metabolic effects at high doses (low dose studies may be unavailable for this ingredient)		PROPYLENE GLYCOL
Classified as expected to be toxic or harmful		C12-15 PARETH-3
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient)		HEXYLENE GLYCOL, CYCLOMETHICONE, ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT, C11-15 PARETH-9
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		OLETH-2, CETEARETH-20
One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient)		PANTHENOL
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		OLETH-10, OLEIC ACID, GLYCERYL MONOSTEARATE, N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE, DMDM HYDANTOIN, CITRIC ACID, 4-AMINO-2-HYDROXYTOLUENE
Limited evidence of sense organ toxicity		PEG-150/ STEARYL ALCOHOL/ SMDI COPOLYMER, PEG-75 LANOLIN, IODOPROPYNYL BUTYLCARBAMATE
One or more animal studies show broad systemic effects at low doses		RESORCINOL
Limited evidence of cardiovascular or blood toxicity		ETHOXYDIGLYCOL
One or more animal studies show blood effects at low doses		ETIDRONIC ACID, DISODIUM EDTA, EDTA
One or more animal studies show gastrointestinal effects at very low doses		HYDROGEN PEROXIDE
Possible human immune system toxicant		SODIUM SULFITE, P-AMINOPHENOL, ETHANOLAMINE
Known human respiratory toxicant		P-PHENYLENEDIAMINE
Known human lung and skin toxicant	products that may be aerosolized (airborne); products for use on skin	1-NAPHTHOL

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Occupational hazards related to handling		HYDROGEN PEROXIDE, ETHANOLAMINE
Ingredient not fully labeled - identity unknown		FRAGRANCE

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Designated as safe for general or specific, limited use in food		PEG-75 LANOLIN, TOCOPHEROL, THYMUS VULGARIS (COMMON THYME) EXTRACT, SODIUM SULFITE, RESORCINOL, PROPYLENE GLYCOL, PEG-150/ STEARYL ALCOHOL/ SMDI COPOLYMER, OLEIC ACID, HYDROLYZED VEGETABLE PROTEIN, HYDROGEN PEROXIDE, GLYCERYL MONOSTEARATE, ETIDRONIC ACID, ETHOXYDIGLYCOL, ETHANOLAMINE, DISODIUM EDTA, CITRIC ACID, ASCORBIC ACID (VITAMIN C), ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT
Used in food or as an additive with limited or no toxicity information available		THYMUS VULGARIS (COMMON THYME) EXTRACT, PANTHENOL, ACHILLEA MILLEFOLIUM (COMMON YARROW) EXTRACT

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Suspected to be an environmental toxin		C12-15 PARETH-3, CYCLOMETHICONE
Not suspected to be an environmental toxin		EDTA
Wildlife and environmental toxicity		RESORCINOL, P-PHENYLENEDIAMINE, P-AMINOPHENOL

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show skin irritation at high doses		C12-15 PARETH-3, SODIUM SULFITE, IODOPROPYNYL BUTYLCARBAMATE, 4-AMINO-2-HYDROXYTOLUENE
One or more animal studies show skin irritation at moderate doses		C11-15 PARETH-9, TRITICUM VULGARE (WHEAT) GERM OIL, P-AMINOPHENOL, ETHOXYDIGLYCOL, CYCLOMETHICONE, CITRIC ACID, ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT
One or more animal studies show skin irritation at low doses		OLETH-2, OLETH-10, OLEIC ACID, CETEARETH-20
Human skin irritant - moderate evidence		HYDROGEN PEROXIDE, ETHANOLAMINE
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	OLEYL ALCOHOL, DMDM HYDANTOIN
Classified as skin irritant		PROPYLENE GLYCOL, RESORCINOL, P-PHENYLENEDIAMINE, HEXYLENE GLYCOL, EDTA, 1-NAPHTHOL

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Missing safety data noted by cosmetic industry review		1-NAPHTHOL
Safety assessment was based on related chemical		PEG-75 LANOLIN, OLETH-2
Insufficient data to determine safety		P-PHENYLENEDIAMINE
Safety assessment was based on related chemical		IODOPROPYNYL BUTYLCARBAMATE, SODIUM COCOAMPHOPROPIONATE, ASCORBIC ACID (VITAMIN C), OLETH-10
Missing safety data noted by cosmetic industry review		ALOE BARBADENSIS (ALOE VERA) FLOWER EXTRACT, P-AMINOPHENOL, P-PHENYLENEDIAMINE
Insufficient data to determine safety		1-NAPHTHOL, 4-AMINO-2-HYDROXYTOLUENE, ACHILLEA MILLEFOLIUM (COMMON YARROW) EXTRACT, P-AMINOPHENOL
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		TRITICUM VULGARE (WHEAT) GERM OIL, PEG-75 LANOLIN
Missing safety data noted by cosmetic industry review		4-AMINO-2-HYDROXYTOLUENE
Safety assessment was based on related chemical		PROPYLENE GLYCOL
Considered safe based on assumption of low absorption		4-AMINO-2-HYDROXYTOLUENE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		TOCOPHEROL, PANTHENOL, RESORCINOL, P-AMINOPHENOL, P-PHENYLENEDIAMINE, ETHOXYDIGLYCOL, OLETH-2, SODIUM SULFITE, OLEYL ALCOHOL, OLETH-10, DMDM HYDANTOIN, OLEIC ACID, HEXYLENE GLYCOL, GLYCERYL MONOSTEARATE, EDTA, DISODIUM EDTA, ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT, ASCORBIC ACID (VITAMIN C), N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE, CYCLOMETHICONE, CETEARYL ALCOHOL, 4-AMINO-2-HYDROXYTOLUENE, 1-NAPHTHOL
Not assessed for safety in cosmetics by industry panel		SOYTRIMONIUM CHLORIDE, KINGINKA EKISU, HELIANTHUS ANNUUS (SUNFLOWER) EXTRACT, C12-15 PARETH-3, C11-15 PARETH-9, TRIMETHYLSILYLAMODIMETHICONE, THYMUS VULGARIS (COMMON THYME) EXTRACT, STEARAMIDOPROPYL DIMETHYLAMINE, SIMETHICONE, PEG-150/ STEARYL ALCOHOL/ SMDI COPOLYMER, OLEAMIDE MIPA, HYDROLYZED VEGETABLE PROTEIN, HYDROGEN PEROXIDE, FRAGRANCE, ETIDRONIC ACID, EMULSIFYING WAX, DILINOLEIC ACID, CITRIC ACID, BELLIS PERENNIS (DAISY) FLOWER EXTRACT, BEHENTRIMONIUM CHLORIDE, ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to low doses		1-NAPHTHOL
Allowed workplace exposures restricted to very low doses		P-PHENYLENEDIAMINE
Allowed workplace exposures restricted to low doses		ETHANOLAMINE, HYDROGEN PEROXIDE, P-AMINOPHENOL, RESORCINOL

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		HYDROGEN PEROXIDE
One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood		P-AMINOPHENOL
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		CITRIC ACID, CYCLOMETHICONE, PROPYLENE GLYCOL
One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood		ETIDRONIC ACID