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66% of breath fresheners have lower concerns
55% of tooth whitenings have lower concerns
61% of toothpastes have lower concerns




Compact for Safe Cosmetics
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Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes |
Ingredients from packaging: Active Ingredients: Sodium Flouride (0.24%). Inactive Ingredients: Sodium Bicarbonate (Baking Soda), Water, Sorbitol Glycerin, Hydrated Silica, Tetrasodium Pyrophosphate, Flavor, Sodium Lauroyl Sulfate, Sodium Saccharin, Sodium Lauroyl Sarcosinate, Cellulose Gum, Sodium Hydroxide, Mica, Titaniuim Dioxide, Blue 1, Yellow #5.
Directions from packaging: Do not swallow. Supervise children as necessary until capable of using without supervision. Adults and children 2 years and older: brush teeth thoroughly after meals or at least twice a day, or use as directed by a dentist or physician. Children under 6 years: instruct in good brushing and rinsing habits (to minimize swallowing). Children under 2 years: ask a dentist or physician.
Warnings from packaging: Keep out of reach of children under 6 years of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away. Image and Description may vary from actual product due to Continuous manufacturer Product updates. Information we provide is for your reference only.
| score | data gap | concerns | |
| SODIUM FLUORIDE SODIUM FLOURIDE (Active Ingredient) | 9 | 63% | Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Neurotoxicity, Endocrine disruption, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Occupational hazards, Biochemical or cellular level changes |
| FLAVOR | 4 | 100% | Miscellaneous |
| TITANIUM DIOXIDE (NON-NANO) TITANIUIM DIOXIDE | 1 | 81% | Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards, Biochemical or cellular level changes |
| SODIUM LAUROYL SARCOSINATE | 4 | 73% | Violations, restrictions & warnings, Enhanced skin absorption, Contamination concerns (NITROSAMINES) |
| FD&C YELLOW 5 | 2 | 82% | Neurotoxicity, Organ system toxicity (non-reproductive) |
| SODIUM HYDROXIDE | 3 | 77% | Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| MICA | 3 | 75% | Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Occupational hazards |
| SODIUM LAURYL SULFATE SODIUM LAUROYL SULFATE | 3 | 68% | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| FD&C BLUE 1 | 1 | 83% | none identified |
| TETRASODIUM PYROPHOSPHATE | 2 | 82% | Neurotoxicity, Organ system toxicity (non-reproductive), Occupational hazards |
| SODIUM BICARBONATE | 2 | 80% | none identified |
| SODIUM SACCHARIN | 2 | 80% | Neurotoxicity |
| HYDRATED SILICA | 2 | 79% | Persistence and bioaccumulation |
| GLYCERIN | 2 | 74% | Organ system toxicity (non-reproductive), Occupational hazards |
| SORBITOL | 1 | 88% | none identified |
| CELLULOSE GUM | 1 | 80% | none identified |
| WATER | 0 | 0% | innocuous |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show tumor formation at high doses | CELLULOSE GUM | |
| One or more in vitro tests on mammalian cells show positive mutation results | TITANIUM DIOXIDE (NON-NANO), SORBITOL, SODIUM SACCHARIN, SODIUM LAURYL SULFATE, SODIUM HYDROXIDE, SODIUM BICARBONATE, GLYCERIN, FD&C YELLOW 5 | |
| One or more animal studies show tumor formation at low doses | SODIUM FLUORIDE | |
| Cancer - not classifiable/not likely to be human carcinogen | HYDRATED SILICA, FD&C BLUE 1 |
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show reproductive effects at high doses | SODIUM SACCHARIN, SODIUM LAURYL SULFATE, FD&C YELLOW 5 | |
| One or more animal studies show reproductive effects at moderate doses | SODIUM BICARBONATE, GLYCERIN, CELLULOSE GUM | |
| Human nervous system toxicant - moderate evidence | SODIUM FLUORIDE |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | SODIUM LAURYL SULFATE | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | SODIUM FLUORIDE | |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | SODIUM LAUROYL SARCOSINATE | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit) | SODIUM LAUROYL SARCOSINATE, SODIUM LAUROYL SARCOSINATE |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show brain and nervous system effects at high doses | SODIUM BICARBONATE, FD&C BLUE 1, GLYCERIN | |
| One or more animal studies show brain and nervous system effects at moderate doses | SODIUM LAURYL SULFATE | |
| One or more animal studies show brain and nervous system effects at very low doses | SODIUM SACCHARIN | |
| One or more animal studies show brain and nervous system effects at low doses | TETRASODIUM PYROPHOSPHATE | |
| One or more animal studies show brain and nervous system effects at very low doses | FD&C YELLOW 5, SODIUM HYDROXIDE | |
| Strong evidence of human neurotoxicity | SODIUM FLUORIDE |
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show endocrine system disruption at high doses | SODIUM LAURYL SULFATE, GLYCERIN | |
| One or more studies show endocrine system disruption at low doses | SODIUM FLUORIDE |
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show immune effects at low doses | TITANIUM DIOXIDE (NON-NANO) | |
| One or more animal studies show gastrointestinal effects at moderate doses | MICA |
*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not suspected to be bioaccumulative | TITANIUM DIOXIDE (NON-NANO), SODIUM HYDROXIDE | |
| Not suspected to be persistent | SODIUM LAURYL SULFATE | |
| Persistent, bioaccumulative in wildlife and humans | HYDRATED SILICA, MICA |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show gastrointestinal effects at high doses (low dose studies may be unavailable for this ingredient) | SORBITOL, SODIUM SACCHARIN, CELLULOSE GUM | |
| One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient) | FD&C BLUE 1 | |
| One or more animal studies show cardiovascular effects at moderate doses (low dose studies may be unavailable for this ingredient) | SODIUM BICARBONATE | |
| One or more animal studies show metabolic effects at low doses | TETRASODIUM PYROPHOSPHATE, SODIUM LAURYL SULFATE | |
| One or more animal studies show musculoskeletal effects at very low doses | FD&C YELLOW 5, SODIUM HYDROXIDE, GLYCERIN, SODIUM FLUORIDE, TITANIUM DIOXIDE (NON-NANO) | |
| Possible human respiratory toxicant | MICA |
*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Occupational hazards related to handling | SODIUM HYDROXIDE, SODIUM FLUORIDE | |
| Ingredient not fully labeled - identity unknown | FLAVOR |
*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Designated as safe for general or specific, limited use in food | TITANIUM DIOXIDE (NON-NANO), TETRASODIUM PYROPHOSPHATE, SORBITOL, SODIUM SACCHARIN, SODIUM LAURYL SULFATE, SODIUM HYDROXIDE, SODIUM FLUORIDE, SODIUM BICARBONATE, GLYCERIN, FD&C YELLOW 5, FD&C BLUE 1, CELLULOSE GUM | |
| Used in food or as an additive with limited or no toxicity information available | SODIUM FLUORIDE |
*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Suspected to be an environmental toxin | SODIUM LAURYL SULFATE | |
| Not suspected to be an environmental toxin | TITANIUM DIOXIDE (NON-NANO), SODIUM HYDROXIDE |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show skin irritation at moderate doses | TITANIUM DIOXIDE (NON-NANO), SODIUM BICARBONATE, GLYCERIN | |
| One or more animal studies show skin irritation at very low doses | SODIUM LAURYL SULFATE, SODIUM HYDROXIDE |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | CELLULOSE GUM, SODIUM BICARBONATE | |
| Not assessed for safety in cosmetics by industry panel | HYDRATED SILICA, FLAVOR, TITANIUM DIOXIDE (NON-NANO), TETRASODIUM PYROPHOSPHATE, SORBITOL, SODIUM SACCHARIN, SODIUM HYDROXIDE, GLYCERIN |
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to low doses | MICA | |
| Allowed workplace exposures restricted to moderate doses | GLYCERIN, TETRASODIUM PYROPHOSPHATE | |
| Allowed workplace exposures restricted to very low doses | SODIUM FLUORIDE | |
| No workplace limits set | SODIUM HYDROXIDE | |
| Allowed workplace exposures restricted to low doses | TITANIUM DIOXIDE (NON-NANO) |
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood | SODIUM LAURYL SULFATE | |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | CELLULOSE GUM, GLYCERIN, SODIUM BICARBONATE | |
| One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood | TITANIUM DIOXIDE (NON-NANO), SODIUM FLUORIDE |
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