Neutrogena T-Gel Overnight, Dandruff Treatment (2006 formulation) || Skin Deep: Cosmetic Safety Reviews

NEUTROGENA T-GEL OVERNIGHT, DANDRUFF TREATMENT (2006 FORMULATION)

last updated: 05/01/06 brand: Neutrogena by Johnson & Johnson

SCORE

high hazard (out of 10)

75%

data gap

BUY ONLINE/BETTER PRODUCTS

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80% of dandruff/scalp treatments have lower concerns

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company conducts animal tests.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes

Ingredients from packaging: ACTIVE INGREDIENTS: SALICYLIC ACID 2.0%. INACTIVE INGREDIENTS: WATER, SD ALCOHOL 40 (20%), PEG-8, SODIUM LAURETH-13 CARBOXYLATE, TRIDECETH-9, PEG-5 ETHYLHEXANOATE, UNDECYLENOYL GLYCINE, BHT, BISABOLOL, SODIUM HYDROXIDE, BENZOPHENONE-4, PEG-8/SMDI COPOLYMER, POLYSORBATE 20, FRAGRANCE.

Directions from packaging: For best results, use atleast twice a week or as directed by a doctor. Before bed, spray directly on scalp (hair can be wet or dry), fully covering problem area. Using fingertips, gently massage into scalp. Shampoo the next morning.

Warnings from packaging: For external use only. Ask a doctor before use if you have a condition that covers a large area of the body. When using this product avoid contact with eyes. If contact occurs, rinse eyes thoroughly with water. Stop use and ask a doctor if condition worsens or does not improve after regular use of this product as directed. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away. flammable - Keep away from open fire or flame.

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ingredients

	score	data gap	concerns
FRAGRANCE	8	100%	Neurotoxicity, Allergies/immunotoxicity, Miscellaneous
SALICYLIC ACID (Active Ingredient)	7	66%	Violations, restrictions & warnings, Neurotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Enhanced skin absorption
PEG-5 ETHYLHEXANOATE	4	76%	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
PEG-8	4	76%	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
PEG-8/ SMDI COPOLYMER	4	76%	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
BHT	6	61%	Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards, Biochemical or cellular level changes
SD ALCOHOL 40	5	77%	Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Enhanced skin absorption, Contamination concerns (BRUCINE, T-BUTYL ALCOHOL, BRUCINE SULFATE, QUASSIN)
SULISOBENZONE (BENZOPHENONE-4) (Active Ingredient)	3	66%	Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Enhanced skin absorption
SODIUM LAURETH-13 CARBOXYLATE	3	100%	Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
SODIUM HYDROXIDE	3	77%	Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
TRIDECETH-9	1	88%	Organ system toxicity (non-reproductive)
POLYSORBATE-20	1	84%	none identified
BISABOLOL	1	80%	Enhanced skin absorption
UNDECYLENOYL GLYCINE	0	100%	none identified
WATER	0	0%	innocuous

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not likely to be mutagenic in humans		SULISOBENZONE (BENZOPHENONE-4)
One or more in vitro tests on mammalian cells show positive mutation results		SODIUM HYDROXIDE
Cancer - not classifiable/not likely to be human carcinogen		SALICYLIC ACID
Cancer - limited evidence		SD ALCOHOL 40
Cancer - not classifiable/not likely to be human carcinogen		BHT

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive effects at high doses		POLYSORBATE-20
One or more animal studies show reproductive effects at moderate doses		SALICYLIC ACID
One or more animal studies show reproductive effects at high doses		BHT
Limited evidence of reproductive toxicity		SD ALCOHOL 40

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		SALICYLIC ACID, PEG-8/ SMDI COPOLYMER
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		SALICYLIC ACID
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		PEG-5 ETHYLHEXANOATE, PEG-8
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in cosmetics (concentration limit)		SALICYLIC ACID

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study		SD ALCOHOL 40
One or more animal studies show brain and nervous system effects at moderate doses		BISABOLOL
One or more animal studies show brain and nervous system effects at low doses		SALICYLIC ACID, BHT
Moderate evidence of human neurotoxicity		FRAGRANCE
One or more animal studies show brain and nervous system effects at very low doses		SODIUM HYDROXIDE

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Associated with endocrine disruption		SULISOBENZONE (BENZOPHENONE-4)
One or more animal studies show endocrine system disruption at high doses		BISABOLOL, BHT

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Human skin toxicant - strong evidence		SULISOBENZONE (BENZOPHENONE-4)
Known human immune system toxicant		FRAGRANCE, BHT

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not suspected to be bioaccumulative		SODIUM HYDROXIDE
Not suspected to be persistent		TRIDECETH-9
Persistent, bioaccumulative in wildlife		SALICYLIC ACID

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient)		TRIDECETH-9, BISABOLOL, POLYSORBATE-20
One or more animal studies show sense effects at moderate doses (low dose studies may be unavailable for this ingredient)		SULISOBENZONE (BENZOPHENONE-4)
Limited evidence of sense organ toxicity		PEG-8/ SMDI COPOLYMER, PEG-5 ETHYLHEXANOATE, PEG-8, SD ALCOHOL 40
One or more animal studies show metabolic effects at low doses		SALICYLIC ACID, BHT
One or more animal studies show metabolic effects at very low doses		SODIUM HYDROXIDE

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Occupational hazards related to handling		SODIUM HYDROXIDE, SD ALCOHOL 40
Ingredient not fully labeled - identity unknown		FRAGRANCE

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Designated as safe for general or specific, limited use in food		SODIUM HYDROXIDE, SALICYLIC ACID, POLYSORBATE-20, PEG-8/ SMDI COPOLYMER, PEG-8, PEG-5 ETHYLHEXANOATE, BHT
Used in food or as an additive with limited or no toxicity information available		SD ALCOHOL 40, SALICYLIC ACID

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Suspected to be an environmental toxin		TRIDECETH-9
Not suspected to be an environmental toxin		SODIUM HYDROXIDE

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show skin irritation at moderate doses		TRIDECETH-9, SALICYLIC ACID, POLYSORBATE-20, BISABOLOL
One or more animal studies show skin irritation at low doses		BHT
One or more animal studies show skin irritation at very low doses		SODIUM HYDROXIDE
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	SULISOBENZONE (BENZOPHENONE-4)

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Insufficient data to determine safety		SD ALCOHOL 40
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		BHT, SULISOBENZONE (BENZOPHENONE-4), POLYSORBATE-20
Not assessed for safety in cosmetics by industry panel		SODIUM LAURETH-13 CARBOXYLATE, TRIDECETH-9, UNDECYLENOYL GLYCINE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		BISABOLOL
Not assessed for safety in cosmetics by industry panel		SODIUM HYDROXIDE, PEG-8/ SMDI COPOLYMER, PEG-5 ETHYLHEXANOATE, FRAGRANCE

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to low doses		BHT
No workplace limits set		SODIUM HYDROXIDE

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show biochemical changes at low doses where the human health implications are not yet well understood		BHT