Garnier 100% Color Permanent Color, Deep Burgundy Brown || Skin Deep: Cosmetic Safety Reviews

GARNIER 100% COLOR PERMANENT COLOR, DEEP BURGUNDY BROWN

last updated: 04/01/08 brand: Garnier by L'Oréal

SCORE

high hazard (out of 10)

78%

data gap

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43% of hair color and bleachings have lower concerns

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company conducts animal tests.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes

Ingredients from packaging: Developer, Water - Aqua, Hydrogen Peroxide, Cetearyl Alcohol, Trideceth-2 Carboxamide MEA, Ceteareth-30, Glycerin, Pentasodium Pentetate, Sodium Stannate, Tetrasodium Pyrophosphate, Colorant, Water - Aqua, Deceth-3, Laureth-12, Oleth-30, Deceth-5, Trideceth-2 Carboxamide MEA, Ammonium Hydroxide, Glycerin, Oleic Acid, Hexadimethrine Chloride, Oleyl Alcohol, Polyquaternium-22, 2-Methyl-5-Hydroxyethylaminophenol, P-Phenylenediamine, Fragrance - Parfum, 4-Amino-2-Hydroxytoluene, 2-Amino-3-Hydroxypyridine, Ethanolamine, Ammonium Thiolactate, P-Aminophenol, Ascorbic Acid, EDTA, Polyquaternium-24, N-N-Bis-2-Hydroxyethyl-P-Phenylenediamine Sulfate, Hydroxypropyl Bis-N-Hydroxyethyl-P-Phenylenediamin, Alpha-Isomethyl Ionone, Resorcinol, Conditioner, Water - Aqua, Cetearyl Alcohol, Behentrimonium Chloride, PEG-180, Amodimethicone, Cetyl Esters, Fragrance - Parfum, Methylparaben, Hydroxyethylcellulose, Niacinamide - Vitamin B3, Pyridoxine HCl - Vitamin B6, Citric Acid, Trideceth-12, Linalool, Mica, Chlorhexidine Dihydrochloride, Limonene, Hexyl Cinnamal, Citronellol, Cetrimonium Chloride, Titanium Dioxide - CI 77891, Benzyl Salicylate, Butylphenyl Methylpropional

Directions from packaging: Read and follow the insert.Store between 50 and 80 degrees F.

Warnings from packaging: Haircolor can cause an allergic reaction which, in certain rare cases, can be severe.Therefore, you must follow these precautions.Do not use if:you have already had a reaction to a haircolor productyou have a sensitive, itchy or damaged scalp.If you have a tattoo, the risks of an allergic reaction may be increased.Perform a skin allergy test 48 hours before each use of this product - see insert.Remember to buy your product 2 days ahead of time.Avoid contact of this product with eyes and skin.If product gets into eyes, rinse immediately.Wear gloves provided in kit.Thoroughly rinse hair after application.Wait at least 14 days after bleaching, relaxing or perming before coloring.Do not use over compound henna or progressive color.Keep product out of the reach of children.Do not apply on children.This product contains ingredients which may cause skin irritation on certain individuals and a preliminary test according to accompanying directions should first be made.This product must not be used for dyeing the eyelashes or eyebrows; to do so may cause blindness.

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ingredients

	score	data gap	concerns
METHYLPARABEN	10	63%	Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes
P-PHENYLENEDIAMINE	10	52%	Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
RESORCINOL	10	52%	Cancer, Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
P-AMINOPHENOL	8	57%	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards
FRAGRANCE	8	100%	Neurotoxicity, Allergies/immunotoxicity, Miscellaneous
CETEARETH-30	5	71%	Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
PEG-180	5	69%	Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
ETHANOLAMINE	7	66%	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
HYDROGEN PEROXIDE	3	65%	Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
LILIAL BUTYLPHENYL METHYLPROPIONAL	5	64%	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
BENZYL SALICYLATE	6	62%	Violations, restrictions & warnings, Allergies/immunotoxicity
LIMONENE	6	56%	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
CHLORHEXIDINE DIHYDROCHLORIDE	4	73%	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
4-AMINO-2-HYDROXYTOLUENE	5	67%	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity
CITRONELLOL	4	65%	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
LINALOOL	5	65%	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
UNSPECIFIED COLOR COLORANT	4	100%	Miscellaneous
OLETH-30	3	87%	Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
TITANIUM DIOXIDE (NON-NANO) TITANIUM DIOXIDE - CI 77891	1	81%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards, Biochemical or cellular level changes
ALPHA-ISOMETHYL IONONE	4	68%	Violations, restrictions & warnings, Allergies/immunotoxicity
HEXYL CINNAMAL	4	65%	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
LAURETH-12	3	100%	Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
PYRIDOXINE HCL	3	79%	Developmental/reproductive toxicity, Neurotoxicity
EDTA	3	78%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
MICA	3	75%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Occupational hazards
2-METHYL-5-HYDROXYETHYLAMINOPHENOL	3	73%	Cancer, Allergies/immunotoxicity
CITRIC ACID	2	72%	Violations, restrictions & warnings
CETRIMONIUM CHLORIDE	3	71%	Allergies/immunotoxicity
N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE	3	69%	Cancer, Allergies/immunotoxicity
OLEIC ACID	1	82%	Irritation (skin, eyes, or lungs)
TETRASODIUM PYROPHOSPHATE	2	82%	Neurotoxicity, Organ system toxicity (non-reproductive), Occupational hazards
AMMONIUM HYDROXIDE	2	81%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
NIACINAMIDE	2	81%	Organ system toxicity (non-reproductive), Biochemical or cellular level changes
GLYCERIN	2	74%	Organ system toxicity (non-reproductive), Occupational hazards
BEHENTRIMONIUM CHLORIDE	0	94%	none identified
CETEARYL ALCOHOL	0	93%	none identified
ASCORBIC ACID (VITAMIN C)	1	91%	none identified
DECETH-5	1	88%	Irritation (skin, eyes, or lungs)
SODIUM STANNATE	1	88%	Occupational hazards
TRIDECETH-12	1	88%	Organ system toxicity (non-reproductive)
OLEYL ALCOHOL	1	87%	Irritation (skin, eyes, or lungs)
HYDROXYETHYLCELLULOSE	1	82%	none identified
2-AMINO-3-HYDROXYPYRIDINE	1	75%	Cancer
PENTASODIUM PENTETATE	0	74%	none identified
DECETH-3	0	100%	none identified
HEXADIMETHRINE CHLORIDE	0	100%	none identified
HYDROXYPROPYL BIS HCL HYDROXYPROPYL BIS-N-HYDROXYETHYL-P-PHENYLENEDIAMIN	0	100%	none identified
POLYQUATERNIUM-22	0	100%	none identified
TRIDECETH-2 CARBOXAMIDE MEA	0	100%	none identified
AMMONIUM THIOLACTATE	0	100%	none identified
AMODIMETHICONE	0	99%	none identified
POLYQUATERNIUM-24	0	94%	none identified
CETYL ESTERS	0	93%	none identified
WATER	0	0%	innocuous

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more in vitro tests non-mammalian cells show positive mutation results		LINALOOL, AMMONIUM HYDROXIDE
One or more in vitro tests on mammalian cells show positive mutation results		PEG-180, TITANIUM DIOXIDE (NON-NANO), PYRIDOXINE HCL, OLEIC ACID, NIACINAMIDE, METHYLPARABEN, GLYCERIN, ETHANOLAMINE, EDTA, CETRIMONIUM CHLORIDE, ASCORBIC ACID (VITAMIN C)
Cancer - limited evidence		N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE, 4-AMINO-2-HYDROXYTOLUENE, 2-METHYL-5-HYDROXYETHYLAMINOPHENOL, 2-AMINO-3-HYDROXYPYRIDINE
Mutagen - limited evidence		P-AMINOPHENOL
Cancer - not classifiable/not likely to be human carcinogen		RESORCINOL, P-PHENYLENEDIAMINE, HYDROGEN PEROXIDE, LIMONENE

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive effects at high doses		HYDROXYETHYLCELLULOSE, ETHANOLAMINE, EDTA, LILIAL,
One or more animal studies show developmental effects at high doses		LIMONENE
One or more animal studies show reproductive effects at moderate doses		P-AMINOPHENOL, GLYCERIN
One or more animal studies show reproductive effects at very low doses		PYRIDOXINE HCL, PEG-180
Human nervous system toxicant - moderate evidence		P-PHENYLENEDIAMINE

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		PEG-180, ETHANOLAMINE, CHLORHEXIDINE DIHYDROCHLORIDE, 4-AMINO-2-HYDROXYTOLUENE, N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE, P-AMINOPHENOL, P-PHENYLENEDIAMINE, RESORCINOL
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Fragrance subject to restrictions: safe only within recommended use or concentration limitsn)		LILIAL, CITRONELLOL, HEXYL CINNAMAL
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		CETRIMONIUM CHLORIDE, CETEARETH-30, 2-METHYL-5-HYDROXYETHYLAMINOPHENOL, 2-AMINO-3-HYDROXYPYRIDINE
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel		P-PHENYLENEDIAMINE, 4-AMINO-2-HYDROXYTOLUENE, BENZYL SALICYLATE, P-AMINOPHENOL, ALPHA-ISOMETHYL IONONE, LIMONENE, LINALOOL
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		CHLORHEXIDINE DIHYDROCHLORIDE, CITRIC ACID, P-PHENYLENEDIAMINE, RESORCINOL, CHLORHEXIDINE DIHYDROCHLORIDE
Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Unsafe in products left on skin and not rinsed off	products that are intended to be left on the skin	ETHANOLAMINE
Violation of government restrictions - Banned or found unsafe for use in cosmetics		METHYLPARABEN

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show brain and nervous system effects at high doses		NIACINAMIDE, HYDROXYETHYLCELLULOSE, HEXYL CINNAMAL, GLYCERIN
One or more animal studies show brain and nervous system effects at moderate doses		RESORCINOL
One or more animal studies show brain and nervous system effects at high doses		4-AMINO-2-HYDROXYTOLUENE
One or more animal studies show brain and nervous system effects at moderate doses		P-AMINOPHENOL, OLEIC ACID, METHYLPARABEN, EDTA, ETHANOLAMINE, LINALOOL
One or more animal studies show brain and nervous system effects at low doses		PYRIDOXINE HCL
One or more animal studies show brain and nervous system effects at moderate doses		LILIAL, CETEARETH-30, CITRONELLOL
One or more animal studies show brain and nervous system effects at low doses		TETRASODIUM PYROPHOSPHATE
Strong evidence of human neurotoxicity		P-PHENYLENEDIAMINE
Moderate evidence of human neurotoxicity		FRAGRANCE
One or more animal studies show brain and nervous system effects at very low doses		HYDROGEN PEROXIDE

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Associated with endocrine disruption		LILIAL, BENZYL SALICYLATE
One or more animal studies show endocrine system disruption at high doses		PYRIDOXINE HCL
Human any disruptor - strong evidence		METHYLPARABEN
One or more animal studies show endocrine system disruption at high doses		GLYCERIN, HYDROGEN PEROXIDE, P-PHENYLENEDIAMINE, N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE, 4-AMINO-2-HYDROXYTOLUENE
One or more animal studies show endocrine disruption at moderate doses		NIACINAMIDE
Human any disruptor - strong evidence		RESORCINOL

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show gastrointestinal effects at moderate doses		MICA
One or more animal studies show immune effects at low doses		TITANIUM DIOXIDE (NON-NANO)
Human immune system toxicant - moderate evidence		CHLORHEXIDINE DIHYDROCHLORIDE
Human skin toxicant - strong evidence		N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE, METHYLPARABEN, ETHANOLAMINE, CETRIMONIUM CHLORIDE, 4-AMINO-2-HYDROXYTOLUENE, 2-METHYL-5-HYDROXYETHYLAMINOPHENOL
Possible human immune system toxicant		LINALOOL, HEXYL CINNAMAL, CITRONELLOL, LILIAL, ALPHA-ISOMETHYL IONONE
Known human immune system toxicant		RESORCINOL, P-PHENYLENEDIAMINE, P-AMINOPHENOL, FRAGRANCE, LIMONENE, BENZYL SALICYLATE

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not suspected to be bioaccumulative		PEG-180, TITANIUM DIOXIDE (NON-NANO), EDTA, AMMONIUM HYDROXIDE
Not suspected to be persistent		TRIDECETH-12
Persistent, bioaccumulative in wildlife and humans		MICA

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient)		TRIDECETH-12, HYDROXYETHYLCELLULOSE, LINALOOL, HEXYL CINNAMAL, LIMONENE, CITRONELLOL, BENZYL SALICYLATE
One or more animal studies show liver effects at moderate doses (low dose studies may be unavailable for this ingredient)		PYRIDOXINE HCL, CETEARETH-30, OLETH-30, OLEIC ACID, N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE, CITRIC ACID, 2-METHYL-5-HYDROXYETHYLAMINOPHENOL, 4-AMINO-2-HYDROXYTOLUENE, CETRIMONIUM CHLORIDE
One or more animal studies show metabolic effects at low doses		TETRASODIUM PYROPHOSPHATE, RESORCINOL, EDTA, AMMONIUM HYDROXIDE
One or more animal studies show liver effects at very low doses		NIACINAMIDE, GLYCERIN, HYDROGEN PEROXIDE, TITANIUM DIOXIDE (NON-NANO)
Possible human immune system toxicant		ETHANOLAMINE, P-AMINOPHENOL, MICA
One or more animal studies show broad systemic effects at very low doses		PEG-180
Possible human immune system toxicant		CHLORHEXIDINE DIHYDROCHLORIDE
Known human respiratory toxicant		P-PHENYLENEDIAMINE, METHYLPARABEN

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Occupational hazards related to handling		HYDROGEN PEROXIDE, ETHANOLAMINE, LIMONENE, AMMONIUM HYDROXIDE
Ingredient not fully labeled - identity unknown		UNSPECIFIED COLOR, FRAGRANCE

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Suspected to be an environmental toxin		TRIDECETH-12
Not suspected to be an environmental toxin		EDTA, TITANIUM DIOXIDE (NON-NANO), PEG-180
Wildlife and environmental toxicity		RESORCINOL, P-PHENYLENEDIAMINE, P-AMINOPHENOL, AMMONIUM HYDROXIDE, LIMONENE

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show skin irritation at high doses		4-AMINO-2-HYDROXYTOLUENE
One or more animal studies show skin irritation at moderate doses		TRIDECETH-12, PEG-180, TITANIUM DIOXIDE (NON-NANO), P-AMINOPHENOL, GLYCERIN, CITRIC ACID
One or more animal studies show skin irritation at low doses		OLETH-30, OLEIC ACID, METHYLPARABEN, DECETH-5, CETEARETH-30, LILIAL
One or more animal studies show skin irritation at very low doses		LINALOOL
Human skin irritant - moderate evidence		ETHANOLAMINE, HYDROGEN PEROXIDE
One or more animal studies show skin irritation at very low doses		HEXYL CINNAMAL, CITRONELLOL
Classified as irritant		LIMONENE
Human skin irritant - moderate evidence		CHLORHEXIDINE DIHYDROCHLORIDE, AMMONIUM HYDROXIDE
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	OLEYL ALCOHOL
Classified as irritant		RESORCINOL, P-PHENYLENEDIAMINE, EDTA

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Safety assessment was based on related chemical		AMODIMETHICONE, ASCORBIC ACID (VITAMIN C), CETYL ESTERS, OLETH-30, PENTASODIUM PENTETATE
Missing safety data noted by cosmetic industry review		P-AMINOPHENOL, P-PHENYLENEDIAMINE, PENTASODIUM PENTETATE
Insufficient data to determine safety		4-AMINO-2-HYDROXYTOLUENE, P-AMINOPHENOL, P-PHENYLENEDIAMINE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		OLETH-30
Safety assessment was based on related chemical		OLETH-30
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		RESORCINOL
Missing safety data noted by cosmetic industry review		4-AMINO-2-HYDROXYTOLUENE
Considered safe based on assumption of low absorption		4-AMINO-2-HYDROXYTOLUENE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		NIACINAMIDE, OLEIC ACID, OLEYL ALCOHOL, PENTASODIUM PENTETATE, P-AMINOPHENOL, P-PHENYLENEDIAMINE, METHYLPARABEN, N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE, HYDROXYETHYLCELLULOSE, EDTA, CETYL ESTERS, CETEARYL ALCOHOL
Not assessed for safety in cosmetics by industry panel		HYDROXYPROPYL BIS HCL, LAURETH-12, LINALOOL, POLYQUATERNIUM-22, POLYQUATERNIUM-24, PYRIDOXINE HCL, SODIUM STANNATE, TETRASODIUM PYROPHOSPHATE, TITANIUM DIOXIDE (NON-NANO), TRIDECETH-2 CARBOXAMIDE MEA, UNSPECIFIED COLOR, AMMONIUM THIOLACTATE, PEG-180, TRIDECETH-12
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		4-AMINO-2-HYDROXYTOLUENE, AMODIMETHICONE, ASCORBIC ACID (VITAMIN C)
Not assessed for safety in cosmetics by industry panel		HYDROGEN PEROXIDE, HEXYL CINNAMAL, HEXADIMETHRINE CHLORIDE, GLYCERIN, FRAGRANCE, LIMONENE, DECETH-5, DECETH-3, CITRONELLOL, CITRIC ACID, LILIAL, BENZYL SALICYLATE, BEHENTRIMONIUM CHLORIDE, AMMONIUM HYDROXIDE, ALPHA-ISOMETHYL IONONE

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to low doses		MICA
Allowed workplace exposures restricted to moderate doses		TETRASODIUM PYROPHOSPHATE
Allowed workplace exposures restricted to low doses		SODIUM STANNATE
Allowed workplace exposures restricted to moderate doses		GLYCERIN
Allowed workplace exposures restricted to very low doses		P-PHENYLENEDIAMINE
Allowed workplace exposures restricted to low doses		TITANIUM DIOXIDE (NON-NANO), ETHANOLAMINE, HYDROGEN PEROXIDE, P-AMINOPHENOL, RESORCINOL

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood		TITANIUM DIOXIDE (NON-NANO)
One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood		P-AMINOPHENOL, PYRIDOXINE HCL
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		CITRIC ACID, GLYCERIN, HYDROGEN PEROXIDE
Interferes with gene expresion		METHYLPARABEN
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood		NIACINAMIDE