L'Oréal Couleur Experte Muti-Tonal Color System, Darkest Mahogany Brown/Warmer 3.5 || Skin Deep: Cosmetic Safety Reviews

L'ORéAL COULEUR EXPERTE MUTI-TONAL COLOR SYSTEM, DARKEST MAHOGANY BROWN/WARMER 3.5

last updated: 03/15/09 brand: L'Oréal by L'Oréal

SCORE

high hazard (out of 10)

78%

data gap

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71% of hair color and bleachings have lower concerns

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company conducts animal tests.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes

Ingredients from packaging: Aqua Water, Deceth-3, Laureth-12, Oleth-30, Deceth-5, Trideceth-2 Carboxamide MEA, Ammonium Hydroxide, Glycerin, Oleic Acid, Hexadimethrine Chloride, Oleyl Alcohol, Polyquaternium-6, Parfum Fragrance, 2-Methyl-5-Hydroxyethylaminophenol, 4-Amino-2-Hydroxytoluene, P-Phenylenediamine, 2-Amino-3-Hydroxypyridine, Ethanolamine, Ammonium Thiolactate, P-Aminophenol, Limonene, Geraniol, Resorcinol, Citronellol, Potassium Persulfate, Sodium Silicate, Sodium Persulfate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Urea, Kaolin, Magnesium Stearate, Ammonium Chloride, Diethylhexyl Sodium Sulfosuccinate, VP/VA Copolymer, Polydecene, Sodium Metasilicate, Magnesium Peroxide, EDTA, Titanium Dioxide CI 77891, Cyamopsis Tetragonoloba Guar Gum, Sodium Carboxymethyl Starch, Sodium Benzoate, Aqua Water, Hydrogen Peroxide, Cetearyl Alcohol, Trideceth-2 Carboxamide MEA, Ceteareth-30, Glycerin, Pentasodium Pentetate, Sodium Stannate, Tetrasodium Pyrophosphate, Aqua Water, Cetearyl Alcohol, Glycerin, Behentrimonium Chloride, Candelilla Cera Candelilla Wax, Amodimethicone, Cetyl Esters, Isopropyl Alcohol, Trideceth-12, Chlorhexidine Dihydrochloride, Methylparaben, Cetrimonium Chloride, Prunus Armeniaca Apricot Kernel Oil, Parfum Fragrance

Directions from packaging: Read and follow the insertStore between 50 - 80 degrees F

Warnings from packaging: Haircolor can cause an allergic reaction which, in certain rare cases, can be seriousTherefore, you must follow these precautionsDo not use ifyou have already had a reaction to a haircolor or hair lightening productyou have a sensitive, itchy or damaged scalpPerform a skin allergy test 48 hours before each use of this product (see insert)Remember to buy your product 2 days ahead of timeAvoid contact of this product with eyes and skinIf product gets into eyes, rinse immediatelyWear gloves provided in kitThoroughly rinse hair after applicationDo not use on relaxed hair or after bleaching your hairDo not use over compound henna or progressive colorDo not inhale or ingestKeep product out of the reach of childrenDo not apply on childrenThis product contains ingredients which may cause skin irritation on certain individuals and a preliminary test according to accompanying directions should first be madeThis product must not be used for dyeing the eyelashes or eyebrows; to do so may cause blindnessThis product contains persulfates and other ingredients which may cause serious irritant, respiratory and/or allergic reactionsPrepare and use only in a well-ventilated areaInsert contains important health and safety information

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ingredients

	score	data gap	concerns
METHYLPARABEN	10	63%	Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes
P-PHENYLENEDIAMINE	10	52%	Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
RESORCINOL	10	52%	Cancer, Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
P-AMINOPHENOL	8	57%	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards
FRAGRANCE	8	100%	Neurotoxicity, Allergies/immunotoxicity, Miscellaneous
CETEARETH-30	5	71%	Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
ETHANOLAMINE	7	66%	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
POTASSIUM PERSULFATE	6	66%	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Occupational hazards
SODIUM PERSULFATE	6	69%	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards
HYDROGEN PEROXIDE	3	65%	Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
GERANIOL	6	61%	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
LIMONENE	6	56%	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
CHLORHEXIDINE DIHYDROCHLORIDE	4	73%	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
4-AMINO-2-HYDROXYTOLUENE	5	67%	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity
CITRONELLOL	4	65%	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
OLETH-30	3	87%	Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
TITANIUM DIOXIDE (NON-NANO) TITANIUM DIOXIDE CI 77891	1	81%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards, Biochemical or cellular level changes
ISOPROPYL ALCOHOL	4	72%	Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
UREA	4	67%	Violations, restrictions & warnings, Irritation (skin, eyes, or lungs), Enhanced skin absorption
SODIUM METASILICATE	4	64%	Developmental/reproductive toxicity, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
LAURETH-12	3	100%	Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
CYAMOPSIS TETRAGONOLOBA (GUAR) GUM	1	79%	none identified
EDTA	3	78%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
AMMONIUM CHLORIDE	3	77%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
2-METHYL-5-HYDROXYETHYLAMINOPHENOL	3	73%	Cancer, Allergies/immunotoxicity
CETRIMONIUM CHLORIDE	3	71%	Allergies/immunotoxicity
SODIUM SILICATE	3	70%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
POLYQUATERNIUM-6	2	87%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive)
OLEIC ACID	1	82%	Irritation (skin, eyes, or lungs)
TETRASODIUM PYROPHOSPHATE	2	82%	Neurotoxicity, Organ system toxicity (non-reproductive), Occupational hazards
AMMONIUM HYDROXIDE	2	81%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
DIOCTYL SODIUM SULFOSUCCINATE DIETHYLHEXYL SODIUM SULFOSUCCINATE	2	81%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
KAOLIN	1	79%	Occupational hazards
MAGNESIUM PEROXIDE	0	76%	none identified
GLYCERIN	2	74%	Organ system toxicity (non-reproductive), Occupational hazards
SODIUM BENZOATE	2	69%	Organ system toxicity (non-reproductive)
BEHENTRIMONIUM CHLORIDE	0	94%	none identified
SODIUM CARBOXYMETHYL STARCH	0	94%	none identified
CETEARYL ALCOHOL	0	93%	none identified
VP/ VA COPOLYMER	1	89%	none identified
DECETH-5	1	88%	Irritation (skin, eyes, or lungs)
SODIUM STANNATE	1	88%	Occupational hazards
TRIDECETH-12	1	88%	Organ system toxicity (non-reproductive)
OLEYL ALCOHOL	1	87%	Irritation (skin, eyes, or lungs)
MAGNESIUM STEARATE	1	83%	Occupational hazards
2-AMINO-3-HYDROXYPYRIDINE	1	75%	Cancer
PENTASODIUM PENTETATE	0	74%	none identified
ACRYLATES/ C10-30 ALKYL ACRYLATE CROSSPOLYMER	0	100%	none identified
DECETH-3	0	100%	none identified
HEXADIMETHRINE CHLORIDE	0	100%	none identified
POLYDECENE	0	100%	none identified
TRIDECETH-2 CARBOXAMIDE MEA	0	100%	none identified
AMMONIUM THIOLACTATE	0	100%	none identified
AMODIMETHICONE	0	99%	none identified
PRUNUS ARMENIACA (APRICOT) KERNEL OIL	0	94%	none identified
EUPHORBIA CERIFERA (CANDELILLA) WAX CANDELILLA CERA CANDELILLA WAX	0	93%	none identified
CETYL ESTERS	0	93%	none identified
WATER	0	0%	innocuous

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show tumor formation at high doses		CYAMOPSIS TETRAGONOLOBA (GUAR) GUM
One or more in vitro tests non-mammalian cells show positive mutation results		AMMONIUM HYDROXIDE
One or more in vitro tests on mammalian cells show positive mutation results		UREA, TITANIUM DIOXIDE (NON-NANO), OLEIC ACID, SODIUM BENZOATE, METHYLPARABEN, GLYCERIN, GERANIOL, ETHANOLAMINE, EDTA, CETRIMONIUM CHLORIDE, AMMONIUM CHLORIDE
Cancer - limited evidence		4-AMINO-2-HYDROXYTOLUENE, 2-METHYL-5-HYDROXYETHYLAMINOPHENOL, 2-AMINO-3-HYDROXYPYRIDINE
Mutagen - limited evidence		P-AMINOPHENOL
Cancer - not classifiable/not likely to be human carcinogen		RESORCINOL, P-PHENYLENEDIAMINE, ISOPROPYL ALCOHOL, HYDROGEN PEROXIDE, LIMONENE

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive effects at high doses		UREA, SODIUM BENZOATE, KAOLIN, ETHANOLAMINE, DIOCTYL SODIUM SULFOSUCCINATE, EDTA,
One or more animal studies show developmental effects at high doses		LIMONENE
One or more animal studies show reproductive effects at moderate doses		P-AMINOPHENOL, GLYCERIN
Limited evidence of developmental toxicity		ISOPROPYL ALCOHOL
One or more animal studies show reproductive effects at low doses		SODIUM METASILICATE
Human nervous system toxicant - moderate evidence		P-PHENYLENEDIAMINE

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		SODIUM SILICATE, SODIUM METASILICATE, SODIUM PERSULFATE, SODIUM BENZOATE, CHLORHEXIDINE DIHYDROCHLORIDE, POTASSIUM PERSULFATE, P-AMINOPHENOL, ETHANOLAMINE, CETRIMONIUM CHLORIDE, CETEARETH-30
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel		POTASSIUM PERSULFATE
Determined safe for use in cosmetics, subject to concentration or use limitations - any		RESORCINOL, P-PHENYLENEDIAMINE, 4-AMINO-2-HYDROXYTOLUENE, 2-METHYL-5-HYDROXYETHYLAMINOPHENOL
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel		SODIUM PERSULFATE
Determined safe for use in cosmetics, subject to concentration or use limitations - any		2-AMINO-3-HYDROXYPYRIDINE
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel		P-PHENYLENEDIAMINE, GERANIOL, P-AMINOPHENOL, 4-AMINO-2-HYDROXYTOLUENE, LIMONENE, CITRONELLOL
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		UREA, P-PHENYLENEDIAMINE, CHLORHEXIDINE DIHYDROCHLORIDE, CHLORHEXIDINE DIHYDROCHLORIDE, RESORCINOL
Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Unsafe in products left on skin and not rinsed off	products that are intended to be left on the skin	ETHANOLAMINE, SODIUM PERSULFATE, POTASSIUM PERSULFATE
Violation of government restrictions - Banned or found unsafe for use in cosmetics		METHYLPARABEN

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show brain and nervous system effects at high doses		GLYCERIN, 4-AMINO-2-HYDROXYTOLUENE
One or more animal studies show brain and nervous system effects at moderate doses		UREA, SODIUM BENZOATE, RESORCINOL, P-AMINOPHENOL, POLYQUATERNIUM-6, OLEIC ACID, METHYLPARABEN, KAOLIN, GERANIOL, ETHANOLAMINE, EDTA, DIOCTYL SODIUM SULFOSUCCINATE, CITRONELLOL
One or more animal studies show brain and nervous system effects at low doses		TETRASODIUM PYROPHOSPHATE
One or more animal studies show brain and nervous system effects at moderate doses		CETEARETH-30, AMMONIUM CHLORIDE
Moderate evidence of human neurotoxicity		FRAGRANCE
One or more animal studies show brain and nervous system effects at very low doses		HYDROGEN PEROXIDE
Strong evidence of human neurotoxicity		P-PHENYLENEDIAMINE, ISOPROPYL ALCOHOL

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show endocrine system disruption at high doses		P-PHENYLENEDIAMINE, HYDROGEN PEROXIDE, GLYCERIN, CYAMOPSIS TETRAGONOLOBA (GUAR) GUM, AMMONIUM CHLORIDE, 4-AMINO-2-HYDROXYTOLUENE
Human any disruptor - strong evidence		RESORCINOL, METHYLPARABEN

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show immune effects at low doses		TITANIUM DIOXIDE (NON-NANO)
Human immune system toxicant - moderate evidence		CHLORHEXIDINE DIHYDROCHLORIDE
Human skin toxicant - strong evidence		SODIUM SILICATE, SODIUM PERSULFATE, SODIUM METASILICATE, POTASSIUM PERSULFATE, METHYLPARABEN, ETHANOLAMINE, CETRIMONIUM CHLORIDE
Known human immune system toxicant		RESORCINOL
Possible human immune system toxicant		CITRONELLOL
Human skin toxicant - strong evidence		2-METHYL-5-HYDROXYETHYLAMINOPHENOL, 4-AMINO-2-HYDROXYTOLUENE
Known human immune system toxicant		P-PHENYLENEDIAMINE, P-AMINOPHENOL, GERANIOL, FRAGRANCE, LIMONENE

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not suspected to be bioaccumulative		TITANIUM DIOXIDE (NON-NANO), SODIUM SILICATE, POLYQUATERNIUM-6, ISOPROPYL ALCOHOL, EDTA, AMMONIUM HYDROXIDE, AMMONIUM CHLORIDE
Not suspected to be persistent		TRIDECETH-12

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Classified as expected to be toxic or harmful		SODIUM SILICATE
One or more animal studies show metabolic effects at high doses (low dose studies may be unavailable for this ingredient)		VP/ VA COPOLYMER, TRIDECETH-12, POLYQUATERNIUM-6, MAGNESIUM STEARATE, LIMONENE, CYAMOPSIS TETRAGONOLOBA (GUAR) GUM, CITRONELLOL
One or more animal studies show liver effects at moderate doses (low dose studies may be unavailable for this ingredient)		CETEARETH-30, SODIUM METASILICATE, OLETH-30, POTASSIUM PERSULFATE, OLEIC ACID, CETRIMONIUM CHLORIDE, 4-AMINO-2-HYDROXYTOLUENE, 2-METHYL-5-HYDROXYETHYLAMINOPHENOL, UREA
Limited evidence of sense organ toxicity		ISOPROPYL ALCOHOL
One or more animal studies show metabolic effects at low doses		TETRASODIUM PYROPHOSPHATE, SODIUM BENZOATE, SODIUM PERSULFATE, EDTA, GERANIOL, RESORCINOL, DIOCTYL SODIUM SULFOSUCCINATE, AMMONIUM HYDROXIDE
One or more animal studies show kidney or renal system effects at very low doses		GLYCERIN, HYDROGEN PEROXIDE, TITANIUM DIOXIDE (NON-NANO), AMMONIUM CHLORIDE
Possible human immune system toxicant		P-AMINOPHENOL, ETHANOLAMINE, CHLORHEXIDINE DIHYDROCHLORIDE
Known human respiratory toxicant		P-PHENYLENEDIAMINE, METHYLPARABEN

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Occupational hazards related to handling		SODIUM METASILICATE, POTASSIUM PERSULFATE, HYDROGEN PEROXIDE, ISOPROPYL ALCOHOL, ETHANOLAMINE, LIMONENE, AMMONIUM HYDROXIDE
Ingredient not fully labeled - identity unknown		FRAGRANCE

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Suspected to be an environmental toxin		TRIDECETH-12, POLYQUATERNIUM-6, AMMONIUM CHLORIDE
Not suspected to be an environmental toxin		TITANIUM DIOXIDE (NON-NANO), SODIUM SILICATE, ISOPROPYL ALCOHOL
Wildlife and environmental toxicity		RESORCINOL
Not suspected to be an environmental toxin		EDTA
Wildlife and environmental toxicity		P-PHENYLENEDIAMINE, P-AMINOPHENOL, LIMONENE, AMMONIUM HYDROXIDE

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show skin irritation at high doses		SODIUM BENZOATE, 4-AMINO-2-HYDROXYTOLUENE
One or more animal studies show skin irritation at moderate doses		TRIDECETH-12, TITANIUM DIOXIDE (NON-NANO), P-AMINOPHENOL, GLYCERIN
One or more animal studies show skin irritation at low doses		OLETH-30, UREA, OLEIC ACID, METHYLPARABEN, DIOCTYL SODIUM SULFOSUCCINATE, DECETH-5, CETEARETH-30
One or more animal studies show skin irritation at very low doses		GERANIOL, CITRONELLOL
Human skin irritant - moderate evidence		HYDROGEN PEROXIDE, ETHANOLAMINE, AMMONIUM HYDROXIDE, CHLORHEXIDINE DIHYDROCHLORIDE
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	SODIUM SILICATE, OLEYL ALCOHOL
Classified as irritant		SODIUM METASILICATE, RESORCINOL, POTASSIUM PERSULFATE, P-PHENYLENEDIAMINE, ISOPROPYL ALCOHOL, EDTA, LIMONENE, AMMONIUM CHLORIDE

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Safety assessment was based on related chemical		OLETH-30, AMODIMETHICONE, CETYL ESTERS, MAGNESIUM STEARATE, OLETH-30, PENTASODIUM PENTETATE, SODIUM METASILICATE
Insufficient data to determine safety		4-AMINO-2-HYDROXYTOLUENE, P-AMINOPHENOL, P-PHENYLENEDIAMINE
Missing safety data noted by cosmetic industry review		PENTASODIUM PENTETATE, P-PHENYLENEDIAMINE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		CETYL ESTERS
Missing safety data noted by cosmetic industry review		4-AMINO-2-HYDROXYTOLUENE, P-AMINOPHENOL
Considered safe based on assumption of low absorption		4-AMINO-2-HYDROXYTOLUENE, SODIUM METASILICATE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		OLETH-30
Considered safe based on assumption of low absorption		SODIUM SILICATE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		RESORCINOL, SODIUM METASILICATE, UREA, SODIUM SILICATE, PENTASODIUM PENTETATE, P-PHENYLENEDIAMINE, OLEYL ALCOHOL, P-AMINOPHENOL, OLEIC ACID, METHYLPARABEN, MAGNESIUM STEARATE, CETEARYL ALCOHOL, EDTA, DIOCTYL SODIUM SULFOSUCCINATE, AMODIMETHICONE, EUPHORBIA CERIFERA (CANDELILLA) WAX, 4-AMINO-2-HYDROXYTOLUENE
Not assessed for safety in cosmetics by industry panel		TRIDECETH-12, AMMONIUM THIOLACTATE, VP/ VA COPOLYMER, TRIDECETH-2 CARBOXAMIDE MEA, TITANIUM DIOXIDE (NON-NANO), TETRASODIUM PYROPHOSPHATE, SODIUM STANNATE, SODIUM CARBOXYMETHYL STARCH, PRUNUS ARMENIACA (APRICOT) KERNEL OIL, POLYQUATERNIUM-6, POLYDECENE, MAGNESIUM PEROXIDE, LAURETH-12, ISOPROPYL ALCOHOL, HYDROGEN PEROXIDE, HEXADIMETHRINE CHLORIDE, GLYCERIN, GERANIOL, FRAGRANCE, LIMONENE, DECETH-5, DECETH-3, CYAMOPSIS TETRAGONOLOBA (GUAR) GUM, CITRONELLOL, BEHENTRIMONIUM CHLORIDE, AMMONIUM HYDROXIDE, AMMONIUM CHLORIDE, ACRYLATES/ C10-30 ALKYL ACRYLATE CROSSPOLYMER

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to moderate doses		MAGNESIUM STEARATE, TETRASODIUM PYROPHOSPHATE
Allowed workplace exposures restricted to high doses		ISOPROPYL ALCOHOL
Allowed workplace exposures restricted to moderate doses		GLYCERIN
Allowed workplace exposures restricted to low doses		SODIUM STANNATE,
Allowed workplace exposures restricted to low doses		P-AMINOPHENOL, RESORCINOL
Allowed workplace exposures restricted to low doses		KAOLIN
Allowed workplace exposures restricted to very low doses		P-PHENYLENEDIAMINE, POTASSIUM PERSULFATE, SODIUM PERSULFATE
Allowed workplace exposures restricted to low doses		TITANIUM DIOXIDE (NON-NANO), AMMONIUM CHLORIDE, ETHANOLAMINE, HYDROGEN PEROXIDE

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood		TITANIUM DIOXIDE (NON-NANO)
One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood		P-AMINOPHENOL
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		DIOCTYL SODIUM SULFOSUCCINATE, GLYCERIN, HYDROGEN PEROXIDE, SODIUM BENZOATE
Interferes with gene expresion		METHYLPARABEN