Clairol Nice 'n Easy Root Touch-Up One Application Permanent Hair Color, Dark Brown 4 || Skin Deep: Cosmetic Safety Reviews

CLAIROL NICE 'N EASY ROOT TOUCH-UP ONE APPLICATION PERMANENT HAIR COLOR, DARK BROWN 4

last updated: 03/15/09 brand: Clairol by Procter & Gamble

SCORE

high hazard (out of 10)

79%

data gap

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74% of hair color and bleachings have lower concerns

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company conducts animal tests.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes

Ingredients from packaging: Water, C12-15 Pareth-3, Cocamide MEA, Oleth-10, Dilinoleic Acid, Linoleamido-Propyl Dimethylamine Dimer Dilinoleate, Steareth-21, Ammonium Hydroxide, Behentrimonium Chloride, Polyquaternium-22, Fragrance, Sodium Sulfate, Erythorbic Acid, Sodium Sulfite, Sodium Metasilicate, EDTA, Algae Extract, Sorbitol, P-Phenylenediamine, N-N-Bis-2-Hydroxyethyl-P-Phenylenediamine Sulfate, 1-Naphthol, Resorcinol, Caramel, Mica, Iron Oxides, M-Aminophenol, P-Aminophenol, Titanium Dioxide, Water, Hydrogen Peroxide, Cetearyl Alcohol, Laureth-23, Steareth-21, Ceteareth-20, Polyquaternium-37, Propylene Glycol Dicaprylate/Dicaprate, Styrene/VP Copolymer, PPG-1 Trideceth-6, Etidronic Acid

Directions from packaging: Important:Hair color products may cause allergic reactions which in rare instances can be serious.Do not color if you have had a previous reaction or if scalp is irritated or injured.To help minimize your risk, perform the skin allergy test 48 hours before coloring.Follow enclosed directions.

Warnings from packaging: This product contains ingredients which may cause skin irritation on certain individuals and a preliminary test according to accompanying directions should first be made.This product must not be used for dyeing the eyelashes or eyebrows - to do so may cause blindness.Keep out of the reach of children.

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ingredients

	score	data gap	concerns
P-PHENYLENEDIAMINE	10	52%	Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
RESORCINOL	10	52%	Cancer, Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
P-AMINOPHENOL	8	57%	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards
FRAGRANCE	8	100%	Neurotoxicity, Allergies/immunotoxicity, Miscellaneous
CETEARETH-20	5	71%	Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
1-NAPHTHOL	8	60%	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
HYDROGEN PEROXIDE	3	65%	Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
M-AMINOPHENOL	6	65%	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Occupational hazards
LAURETH-23	5	83%	Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
OLETH-10	3	87%	Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
TITANIUM DIOXIDE (NON-NANO)	1	81%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards, Biochemical or cellular level changes
COCAMIDE MEA	2	75%	Contamination concerns (NITROSAMINES)
SODIUM METASILICATE	4	64%	Developmental/reproductive toxicity, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
SODIUM SULFITE	3	87%	Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
EDTA	3	78%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
MICA	3	75%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Occupational hazards
N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE	3	69%	Cancer, Allergies/immunotoxicity
IRON OXIDES	2	85%	Persistence and bioaccumulation, Enhanced skin absorption
AMMONIUM HYDROXIDE	2	81%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
ETIDRONIC ACID	2	79%	Endocrine disruption, Organ system toxicity (non-reproductive)
BEHENTRIMONIUM CHLORIDE	0	94%	none identified
DILINOLEIC ACID	0	94%	none identified
POLYQUATERNIUM-37	0	94%	none identified
CETEARYL ALCOHOL	0	93%	none identified
CARAMEL	1	92%	none identified
PROPYLENE GLYCOL DICAPRYLATE/DICAPRATE	0	90%	Enhanced skin absorption
STEARETH-21	1	89%	none identified
SORBITOL	1	88%	none identified
ERYTHORBIC ACID	1	87%	none identified
C12-15 PARETH-3	1	86%	Organ system toxicity (non-reproductive)
SODIUM SULFATE	1	73%	none identified
LINOLEAMIDOPROPYL DIMETHYLAMINE DIMER DILINOLEATE	0	100%	none identified
POLYQUATERNIUM-22	0	100%	none identified
PPG-1 TRIDECETH-6	0	100%	none identified
ALGAE EXTRACT	0	94%	none identified
STYRENE/ PVP COPOLYMER STYRENE/VP COPOLYMER	0	94%	none identified
WATER	0	0%	innocuous

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Cancer - limited evidence		N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE
One or more in vitro tests on mammalian cells show positive mutation results		CARAMEL, EDTA, ERYTHORBIC ACID, SODIUM SULFITE, SORBITOL, TITANIUM DIOXIDE (NON-NANO)
One or more in vitro tests non-mammalian cells show positive mutation results		AMMONIUM HYDROXIDE, LAURETH-23
Cancer - limited evidence		M-AMINOPHENOL, 1-NAPHTHOL
Mutagen - limited evidence		P-AMINOPHENOL
Cancer - not classifiable/not likely to be human carcinogen		RESORCINOL, P-PHENYLENEDIAMINE, HYDROGEN PEROXIDE

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive effects at high doses		M-AMINOPHENOL, EDTA
One or more animal studies show reproductive effects at moderate doses		P-AMINOPHENOL, ETIDRONIC ACID, 1-NAPHTHOL
One or more animal studies show reproductive effects at low doses		SODIUM METASILICATE
Human nervous system toxicant - moderate evidence		P-PHENYLENEDIAMINE

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		SODIUM SULFATE, SODIUM METASILICATE, COCAMIDE MEA, CETEARETH-20, RESORCINOL, P-PHENYLENEDIAMINE, N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE, P-AMINOPHENOL, M-AMINOPHENOL, 1-NAPHTHOL
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel		P-AMINOPHENOL, P-PHENYLENEDIAMINE, M-AMINOPHENOL, 1-NAPHTHOL
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		P-PHENYLENEDIAMINE, RESORCINOL

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show brain and nervous system effects at moderate doses		EDTA, ETIDRONIC ACID
One or more animal studies show brain and nervous system effects at high doses		C12-15 PARETH-3, 1-NAPHTHOL
One or more animal studies show brain and nervous system effects at moderate doses		RESORCINOL, P-AMINOPHENOL, M-AMINOPHENOL, CETEARETH-20
One or more animal studies show brain and nervous system effects at low doses		SODIUM SULFITE, LAURETH-23
One or more animal studies show brain and nervous system effects at very low doses		HYDROGEN PEROXIDE
Moderate evidence of human neurotoxicity		FRAGRANCE
Strong evidence of human neurotoxicity		P-PHENYLENEDIAMINE

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show endocrine system disruption at high doses		P-PHENYLENEDIAMINE, N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE, HYDROGEN PEROXIDE
One or more animal studies show endocrine disruption at moderate doses		1-NAPHTHOL
One or more studies show endocrine system disruption at low doses		ETIDRONIC ACID
Human any disruptor - strong evidence		RESORCINOL

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Human skin toxicant - strong evidence		SODIUM METASILICATE
Human immune system toxicant - moderate evidence		SODIUM SULFITE
One or more animal studies show gastrointestinal effects at moderate doses		MICA
One or more animal studies show immune effects at low doses		TITANIUM DIOXIDE (NON-NANO)
Human skin toxicant - strong evidence		N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE, 1-NAPHTHOL
Known human immune system toxicant		RESORCINOL
Human skin toxicant - strong evidence		M-AMINOPHENOL
Known human immune system toxicant		P-PHENYLENEDIAMINE, P-AMINOPHENOL, FRAGRANCE

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not suspected to be bioaccumulative		TITANIUM DIOXIDE (NON-NANO), EDTA, AMMONIUM HYDROXIDE
Persistent, bioaccumulative in wildlife and humans		MICA, IRON OXIDES
Not suspected to be persistent		LAURETH-23, C12-15 PARETH-3

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show gastrointestinal effects at moderate doses (low dose studies may be unavailable for this ingredient)		SODIUM METASILICATE, CETEARETH-20
One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient)		ERYTHORBIC ACID, SORBITOL
Classified as expected to be toxic or harmful		C12-15 PARETH-3
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE, OLETH-10, STEARETH-21,
One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient)		SODIUM SULFATE
One or more animal studies show broad systemic effects at low doses		RESORCINOL, LAURETH-23, EDTA, AMMONIUM HYDROXIDE, ETIDRONIC ACID
One or more animal studies show gastrointestinal effects at very low doses		HYDROGEN PEROXIDE, TITANIUM DIOXIDE (NON-NANO)
Possible human respiratory toxicant		MICA, SODIUM SULFITE, P-AMINOPHENOL
Known human respiratory toxicant		P-PHENYLENEDIAMINE
Known human lung and skin toxicant	products that may be aerosolized (airborne); products for use on skin	1-NAPHTHOL

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Ingredient not fully labeled - identity unknown		FRAGRANCE
Occupational hazards related to handling		AMMONIUM HYDROXIDE, HYDROGEN PEROXIDE, SODIUM METASILICATE

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Suspected to be an environmental toxin		LAURETH-23, C12-15 PARETH-3
Wildlife and environmental toxicity		P-PHENYLENEDIAMINE, RESORCINOL
Not suspected to be an environmental toxin		EDTA, TITANIUM DIOXIDE (NON-NANO)
Wildlife and environmental toxicity		AMMONIUM HYDROXIDE, M-AMINOPHENOL, P-AMINOPHENOL

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show skin irritation at high doses		SODIUM SULFITE, C12-15 PARETH-3
One or more animal studies show skin irritation at low doses		CETEARETH-20, OLETH-10
One or more animal studies show skin irritation at moderate doses		M-AMINOPHENOL, P-AMINOPHENOL, TITANIUM DIOXIDE (NON-NANO)
Classified as irritant		RESORCINOL, SODIUM METASILICATE
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	LAURETH-23
Human skin irritant - moderate evidence		AMMONIUM HYDROXIDE, HYDROGEN PEROXIDE
Classified as irritant		1-NAPHTHOL, EDTA, P-PHENYLENEDIAMINE

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Safety assessment was based on related chemical		PROPYLENE GLYCOL DICAPRYLATE/DICAPRATE, OLETH-10, SODIUM METASILICATE, LAURETH-23
Insufficient data to determine safety		P-PHENYLENEDIAMINE, P-AMINOPHENOL, M-AMINOPHENOL, 1-NAPHTHOL
Missing safety data noted by cosmetic industry review		P-PHENYLENEDIAMINE, P-AMINOPHENOL, M-AMINOPHENOL, 1-NAPHTHOL
Considered safe based on assumption of low absorption		SODIUM METASILICATE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		RESORCINOL, PROPYLENE GLYCOL DICAPRYLATE/DICAPRATE, P-PHENYLENEDIAMINE, SODIUM SULFITE, SODIUM METASILICATE, P-AMINOPHENOL, M-AMINOPHENOL, OLETH-10, N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE, EDTA, CETEARYL ALCOHOL, LAURETH-23, ERYTHORBIC ACID, 1-NAPHTHOL
Not assessed for safety in cosmetics by industry panel		STEARETH-21, POLYQUATERNIUM-37, PPG-1 TRIDECETH-6, SORBITOL, STYRENE/ PVP COPOLYMER, TITANIUM DIOXIDE (NON-NANO), C12-15 PARETH-3, DILINOLEIC ACID, ETIDRONIC ACID, FRAGRANCE, HYDROGEN PEROXIDE, LINOLEAMIDOPROPYL DIMETHYLAMINE DIMER DILINOLEATE, POLYQUATERNIUM-22, ALGAE EXTRACT, AMMONIUM HYDROXIDE, BEHENTRIMONIUM CHLORIDE, CARAMEL

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to low doses		MICA,
Allowed workplace exposures restricted to low doses		RESORCINOL, P-AMINOPHENOL, HYDROGEN PEROXIDE, M-AMINOPHENOL, 1-NAPHTHOL
Allowed workplace exposures restricted to very low doses		P-PHENYLENEDIAMINE
Allowed workplace exposures restricted to low doses		TITANIUM DIOXIDE (NON-NANO)

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		HYDROGEN PEROXIDE
One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood		P-AMINOPHENOL, LAURETH-23, ETIDRONIC ACID
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood		TITANIUM DIOXIDE (NON-NANO)