

Compact for Safe Cosmetics
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Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards |
Ingredients from packaging: Butyl Acetate, Ethyl Acetate, Nitrocellulose, Tosylamide/Formaldehyde Resin, Trimethyl Pentanyl Diisobutyrate, SD Alcohol 3-A, Isopropyl Alcohol, Water, Etocrylene, Benzophenone-1, Panthenol, Nylon-12, Violet 2
Directions from packaging: Shake gentlyFirst, apply to clean, dry, bare nails as a base coat and let dryBrush on 1-2 coats of your favorite Sally Hansen protective nail color and let dryFinish with Double Duty as a shiny top coat
Warnings from packaging: FlammableKeep from heat and flame
| score | data gap | concerns | |
| BENZOPHENONE-1 | 5 | 79% | Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive) |
| ETHYL ACETATE | 4 | 78% | Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| D&C VIOLET 2 | 2 | 71% | Cancer, Organ system toxicity (non-reproductive) |
| SD ALCOHOL 3A | 4 | 77% | Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Enhanced skin absorption |
| ISOPROPYL ALCOHOL | 4 | 72% | Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| TOSYLAMIDE/ FORMALDEHYDE RESIN | 4 | 72% | Allergies/immunotoxicity |
| TRIMETHYL PENTANYL DIISOBUTYRATE | 2 | 93% | Persistence and bioaccumulation, Organ system toxicity (non-reproductive) |
| PANTHENOL | 2 | 88% | Multiple, additive exposure sources |
| NITROCELLULOSE | 1 | 94% | Organ system toxicity (non-reproductive) |
| ETOCRYLENE | 1 | 89% | Organ system toxicity (non-reproductive) |
| BUTYL ACETATE | 1 | 78% | Irritation (skin, eyes, or lungs), Occupational hazards |
| NYLON-12 | 0 | 94% | none identified |
| WATER | 0 | 0% | innocuous |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more in vitro tests on mammalian cells show positive mutation results | ETHYL ACETATE | |
| Cancer - limited evidence | SD ALCOHOL 3A, D&C VIOLET 2 | |
| Cancer - not classifiable/not likely to be human carcinogen | ISOPROPYL ALCOHOL |
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Limited evidence of reproductive toxicity | SD ALCOHOL 3A | |
| Human nervous system toxicant - moderate evidence | ETHYL ACETATE | |
| Limited evidence of developmental toxicity | ISOPROPYL ALCOHOL |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Strong evidence of human neurotoxicity | ISOPROPYL ALCOHOL, ETHYL ACETATE | |
| One or more animal studies show brain and nervous system effects at high doses | BENZOPHENONE-1 | |
| nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study | BUTYL ACETATE, SD ALCOHOL 3A |
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Human any disruptor - strong evidence | BENZOPHENONE-1 |
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Human skin toxicant - strong evidence | BENZOPHENONE-1 | |
| Known human immune system toxicant | TOSYLAMIDE/ FORMALDEHYDE RESIN |
*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not suspected to be bioaccumulative | ISOPROPYL ALCOHOL, D&C VIOLET 2 | |
| Not suspected to be persistent | TRIMETHYL PENTANYL DIISOBUTYRATE |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Classified as expected to be toxic or harmful | TRIMETHYL PENTANYL DIISOBUTYRATE, NITROCELLULOSE, D&C VIOLET 2 | |
| Limited evidence of gastrointestinal or liver toxicity | SD ALCOHOL 3A, ETHYL ACETATE, ISOPROPYL ALCOHOL | |
| One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient) | PANTHENOL | |
| One or more animal studies show broad systemic effects at low doses | ETOCRYLENE, BENZOPHENONE-1 |
*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Designated as safe for general or specific, limited use in food | ISOPROPYL ALCOHOL, ETHYL ACETATE, BUTYL ACETATE | |
| Used in food or as an additive with limited or no toxicity information available | SD ALCOHOL 3A, PANTHENOL |
*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Suspected to be an environmental toxin | TRIMETHYL PENTANYL DIISOBUTYRATE | |
| Not suspected to be an environmental toxin | ISOPROPYL ALCOHOL, NITROCELLULOSE, D&C VIOLET 2 |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show skin irritation at moderate doses | TRIMETHYL PENTANYL DIISOBUTYRATE | |
| Classified as skin irritant | products for use on skin | BUTYL ACETATE |
| Classified as irritant | ISOPROPYL ALCOHOL, ETHYL ACETATE |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | SD ALCOHOL 3A, ETHYL ACETATE, PANTHENOL, BUTYL ACETATE, BENZOPHENONE-1 | |
| Not assessed for safety in cosmetics by industry panel | TRIMETHYL PENTANYL DIISOBUTYRATE, NYLON-12, NITROCELLULOSE, ISOPROPYL ALCOHOL, ETOCRYLENE |
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to high doses | BUTYL ACETATE, ETHYL ACETATE, ISOPROPYL ALCOHOL |
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