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Compact for Safe Cosmetics
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Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes |
Ingredients from packaging: Active Ingredients: Pyrithione Zinc 0.1%, Other Ingredients: Water, Mineral Oil, Aloe Barbadensis Leaf Juice, Isopropyl Myistate, Stearyl Alcohol, Ceteareth-20 Carbomer, Simmondsia Chinensis Seed Oil Jojoba, Hydrolyzed Collagen, Propylene Glycol, Tocopheryl Acetate, Methylparaben, Propylparaben, Diazolidinyl Urea, Sodium Lauryl Sulfate, Panthenol, Triethanolamine, Fragrance
Directions from packaging: Apply to the affected area 1-4 times daily, or as directed by a doctor.
Warnings from packaging: For external use only.When using this product do not get into eyes.If contact occurs, rinse eyes thoroughly with water.Stop use and ask a doctor if condition worsens or does not improve after regular use.Keep out of reach of children.If swallowed, get medical help or call a poison control center at once.
| score | data gap | concerns | |
| METHYLPARABEN | 10 | 63% | Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes |
| FRAGRANCE | 8 | 100% | Neurotoxicity, Allergies/immunotoxicity, Miscellaneous |
| CETEARETH-20 | 5 | 71% | Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE) |
| DIAZOLIDINYL UREA | 6 | 59% | Allergies/immunotoxicity, Contamination concerns (FORMALDEHYDE) |
| TRIETHANOLAMINE | 6 | 58% | Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (NITROSAMINES), Occupational hazards |
| PROPYLPARABEN | 5 | 71% | Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive) |
| ZINC PYRITHIONE PYRITHIONE ZINC | 5 | 66% | Violations, restrictions & warnings, Allergies/immunotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive) |
| TOCOPHERYL ACETATE | 4 | 81% | Allergies/immunotoxicity, Contamination concerns (HYDROQUINONE) |
| MINERAL OIL | 2 | 73% | Organ system toxicity (non-reproductive), Occupational hazards |
| PROPYLENE GLYCOL | 4 | 60% | Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption |
| SODIUM LAURYL SULFATE | 3 | 68% | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| PANTHENOL | 2 | 88% | Multiple, additive exposure sources |
| HYDROLYZED COLLAGEN | 0 | 88% | none identified |
| SIMMONDSIA CHINENSIS (JOJOBA) SEED OIL SIMMONDSIA CHINENSIS SEED OIL JOJOBA | 1 | 87% | none identified |
| ISOPROPYL MYRISTATE ISOPROPYL MYISTATE | 1 | 86% | Irritation (skin, eyes, or lungs) |
| STEARYL ALCOHOL | 1 | 84% | Irritation (skin, eyes, or lungs) |
| ALOE BARBADENSIS (ALOE VERA) GEL ALOE BARBADENSIS LEAF JUICE | 1 | 72% | none identified |
| CARBOMER | 0 | 93% | none identified |
| WATER | 0 | 0% | innocuous |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show tumor formation at high doses | STEARYL ALCOHOL, MINERAL OIL | |
| One or more in vitro tests on mammalian cells show positive mutation results | TOCOPHERYL ACETATE, SODIUM LAURYL SULFATE, PROPYLPARABEN, PROPYLENE GLYCOL, METHYLPARABEN, DIAZOLIDINYL UREA | |
| Cancer - not classifiable/not likely to be human carcinogen | TRIETHANOLAMINE |
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show reproductive effects at high doses | SODIUM LAURYL SULFATE | |
| One or more animal studies show reproductive effects at moderate doses | ZINC PYRITHIONE, PROPYLENE GLYCOL, | |
| One or more animal studies show any effects at moderate doses | ALOE BARBADENSIS (ALOE VERA) GEL | |
| One or more animal studies show any effects at low doses | PROPYLPARABEN |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Violation of government restrictions - Banned or found unsafe for use in cosmetics | METHYLPARABEN | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit) | ZINC PYRITHIONE | |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | ALOE BARBADENSIS (ALOE VERA) GEL, CETEARETH-20, DIAZOLIDINYL UREA, PROPYLENE GLYCOL, SODIUM LAURYL SULFATE, TRIETHANOLAMINE |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Moderate evidence of human neurotoxicity | FRAGRANCE | |
| One or more animal studies show brain and nervous system effects at moderate doses | CETEARETH-20, METHYLPARABEN, SODIUM LAURYL SULFATE | |
| One or more animal studies show brain and nervous system effects at high doses | DIAZOLIDINYL UREA, PROPYLENE GLYCOL | |
| One or more animal studies show brain and nervous system effects at moderate doses | ZINC PYRITHIONE |
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show endocrine system disruption at high doses | TRIETHANOLAMINE, SODIUM LAURYL SULFATE | |
| Human any disruptor - strong evidence | METHYLPARABEN, PROPYLPARABEN | |
| One or more animal studies show endocrine system disruption at high doses | DIAZOLIDINYL UREA |
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Limited evidence of skin and immune system toxicity | PROPYLENE GLYCOL, ZINC PYRITHIONE | |
| Human skin toxicant - strong evidence | PROPYLPARABEN, TOCOPHERYL ACETATE | |
| Known human immune system toxicant | TRIETHANOLAMINE | |
| Human skin toxicant - strong evidence | METHYLPARABEN | |
| Known human immune system toxicant | DIAZOLIDINYL UREA, FRAGRANCE |
*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not suspected to be persistent | SODIUM LAURYL SULFATE | |
| Not suspected to be bioaccumulative | TRIETHANOLAMINE | |
| Persistent, bioaccumulative in wildlife | ZINC PYRITHIONE |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show metabolic effects at high doses (low dose studies may be unavailable for this ingredient) | PROPYLENE GLYCOL, SIMMONDSIA CHINENSIS (JOJOBA) SEED OIL, STEARYL ALCOHOL, PANTHENOL, MINERAL OIL, ISOPROPYL MYRISTATE, DIAZOLIDINYL UREA | |
| One or more animal studies show liver effects at moderate doses (low dose studies may be unavailable for this ingredient) | CETEARETH-20, TOCOPHERYL ACETATE, ALOE BARBADENSIS (ALOE VERA) GEL | |
| Limited evidence of sense organ toxicity | PROPYLPARABEN | |
| One or more animal studies show broad systemic effects at low doses | SODIUM LAURYL SULFATE, ZINC PYRITHIONE | |
| Known human any toxicant | METHYLPARABEN | |
| Possible human immune system toxicant | TRIETHANOLAMINE |
*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Ingredient not fully labeled - identity unknown | FRAGRANCE |
*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Designated as safe for general or specific, limited use in food | STEARYL ALCOHOL, TOCOPHERYL ACETATE, TRIETHANOLAMINE, SODIUM LAURYL SULFATE, PROPYLPARABEN, PROPYLENE GLYCOL, MINERAL OIL, METHYLPARABEN, ISOPROPYL MYRISTATE | |
| Used in food or as an additive with limited or no toxicity information available | PANTHENOL | |
| Designated as safe for general or specific, limited use in food | ALOE BARBADENSIS (ALOE VERA) GEL |
*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Wildlife and environmental toxicity | PROPYLPARABEN | |
| Not suspected to be an environmental toxin | TRIETHANOLAMINE | |
| Suspected to be an environmental toxin | SODIUM LAURYL SULFATE, ZINC PYRITHIONE |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show skin irritation at low doses | METHYLPARABEN | |
| One or more animal studies show skin irritation at moderate doses | MINERAL OIL | |
| One or more animal studies show skin irritation at low doses | CETEARETH-20 | |
| One or more animal studies show skin irritation at very low doses | TRIETHANOLAMINE | |
| Human any irritant - strong evidence | products for use around the eyes, on the skin, or may be aerosolized (airborne) | STEARYL ALCOHOL |
| Classified as skin irritant | PROPYLENE GLYCOL | |
| Human any irritant - strong evidence | products for use around the eyes, on the skin, or may be aerosolized (airborne) | ISOPROPYL MYRISTATE, SODIUM LAURYL SULFATE |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Safety assessment was based on related chemical | PROPYLENE GLYCOL | |
| Missing safety data noted by cosmetic industry review | ALOE BARBADENSIS (ALOE VERA) GEL | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | TOCOPHERYL ACETATE, STEARYL ALCOHOL, SIMMONDSIA CHINENSIS (JOJOBA) SEED OIL, PANTHENOL, PROPYLPARABEN, METHYLPARABEN, ISOPROPYL MYRISTATE, HYDROLYZED COLLAGEN, CARBOMER | |
| Not assessed for safety in cosmetics by industry panel | ZINC PYRITHIONE, FRAGRANCE, MINERAL OIL |
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to moderate doses | MINERAL OIL, TRIETHANOLAMINE |
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood | SODIUM LAURYL SULFATE | |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | SIMMONDSIA CHINENSIS (JOJOBA) SEED OIL, PROPYLENE GLYCOL | |
| Interferes with gene expresion | METHYLPARABEN |
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