

Compact for Safe Cosmetics
|
Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes |
Ingredients from packaging: ACTIVE INGREDIENTS: SODIUM MONOFLUOROPHOSPHATE (0.15% W/V FLUORIDE ION). INACTIVE INGREDIENTS: CALCIUM CARBONATE, GLYCERIN, WATER, SODIUM BICARBONATE, CARRAGEENAN, XYLITOL, PEPPERMINT OILS, SODIUM LAURYL SULFATE.
Directions from packaging: Adults and children 2 years of age and older: Brush teeth thoroughly, preferably after each meal or at least twice a day, or as directed by a dentist or doctor. Instruct children under 6 years of age in good brushing and rinsing habits (to minimize swallowing). Supervise children as necessary until capable of using without supervision. Children under 2 years of age: Consult a dentist or doctor. Children under 6: Use a pea-sized amount.
Warnings from packaging: Keep out of reach of children under 6 years of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away. For eternal use only. Individual body chemistry varies. Please discontinue use if rash or irritation occurs.
| score | data gap | concerns | |
| SODIUM MONOFLUOROPHOSPHATE (Active Ingredient) | 6 | 69% | Developmental/reproductive toxicity, Violations, restrictions & warnings, Neurotoxicity, Organ system toxicity (non-reproductive), Occupational hazards |
| CARRAGEENAN | 2 | 75% | Organ system toxicity (non-reproductive), Contamination concerns (DEGRADED CARRAGEENAN), Biochemical or cellular level changes |
| MENTHA PIPERITA (PEPPERMINT) OIL PEPPERMINT OILS | 3 | 73% | Enhanced skin absorption, Contamination concerns (LIMONENE, MENTHOL, MENTHONE) |
| SODIUM LAURYL SULFATE | 3 | 68% | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| SODIUM BICARBONATE | 2 | 80% | none identified |
| GLYCERIN | 2 | 74% | Organ system toxicity (non-reproductive), Occupational hazards |
| XYLITOL | 1 | 88% | none identified |
| CALCIUM CARBONATE | 1 | 87% | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards |
| WATER | 0 | 0% | innocuous |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more in vitro tests on mammalian cells show positive mutation results | SODIUM BICARBONATE | |
| One or more in vitro tests non-mammalian cells show positive mutation results | MENTHA PIPERITA (PEPPERMINT) OIL | |
| One or more in vitro tests on mammalian cells show positive mutation results | SODIUM LAURYL SULFATE, SODIUM MONOFLUOROPHOSPHATE, GLYCERIN | |
| Not likely to be carcinogenic in humans | CARRAGEENAN |
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show reproductive effects at high doses | SODIUM LAURYL SULFATE | |
| One or more animal studies show reproductive effects at moderate doses | SODIUM BICARBONATE, GLYCERIN | |
| Human nervous system toxicant - moderate evidence | SODIUM MONOFLUOROPHOSPHATE |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | SODIUM LAURYL SULFATE, MENTHA PIPERITA (PEPPERMINT) OIL | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | SODIUM MONOFLUOROPHOSPHATE |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show brain and nervous system effects at high doses | XYLITOL, SODIUM BICARBONATE, GLYCERIN | |
| One or more animal studies show brain and nervous system effects at moderate doses | SODIUM LAURYL SULFATE, CARRAGEENAN, MENTHA PIPERITA (PEPPERMINT) OIL | |
| Strong evidence of human neurotoxicity | SODIUM MONOFLUOROPHOSPHATE |
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show endocrine system disruption at high doses | GLYCERIN, SODIUM LAURYL SULFATE |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient) | XYLITOL, MENTHA PIPERITA (PEPPERMINT) OIL | |
| One or more animal studies show broad systemic effects at low doses | SODIUM LAURYL SULFATE | |
| One or more animal studies show cardiovascular effects at moderate doses (low dose studies may be unavailable for this ingredient) | SODIUM BICARBONATE | |
| One or more animal studies show sense organ effects at very low doses | products for use around the eyes, mouth, or lips | CALCIUM CARBONATE |
| One or more animal studies show kidney or renal system effects at very low doses | GLYCERIN, CARRAGEENAN, SODIUM MONOFLUOROPHOSPHATE |
*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Suspected to be an environmental toxin | SODIUM LAURYL SULFATE |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show skin irritation at moderate doses | SODIUM BICARBONATE, GLYCERIN | |
| One or more animal studies show skin irritation at low doses | CALCIUM CARBONATE | |
| One or more animal studies show skin irritation at very low doses | SODIUM LAURYL SULFATE |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | SODIUM BICARBONATE | |
| Not assessed for safety in cosmetics by industry panel | XYLITOL, SODIUM MONOFLUOROPHOSPHATE, GLYCERIN, CARRAGEENAN, CALCIUM CARBONATE |
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to moderate doses | GLYCERIN, CALCIUM CARBONATE | |
| Allowed workplace exposures restricted to low doses | SODIUM MONOFLUOROPHOSPHATE |
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | SODIUM BICARBONATE, XYLITOL, GLYCERIN | |
| One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood | SODIUM LAURYL SULFATE | |
| One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood | CARRAGEENAN |
No items in basket.
Add this product
Looking for a product report that we don't have in Skin Deep? Sign up to enter it into the Skin Deep database and leave product reviews.
We always want Skin Deep to be free to the public, but delivering high-quality research costs time and money. Help by donating just the cost of a bar of soap or bottle of shampoo.
Stay informed with email updates on toxics in everyday products and how they can affect your health.
Find out more about the Campaign for Safe Cosmetics.