

Compact for Safe Cosmetics
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Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: |
Ingredients from packaging: rganic aloe barbadensis (aloe vera) leaf juice, sodium bicarbonate, organic citrus limonum (lemon) essential oil, non-gmo xanthan gum, sea salt, stevia rebaudiana extract, organic backhousia citriadora (lemon myrtle) essential oil
Directions from packaging: Apply with a toothbrush morning and night, after meals
| susanm | ![]() ![]() ![]() ![]() ![]() | "My favorite toothpaste. I look forward to brushing my teeth. Great flavor, clean mouth!!! ..." | Read more. | |
| HealthyChick | "Limonene and geraniol are ingredients of this Miessence toothpaste. They are listed on the toothpaste packaging itself but when you try to research th ..." | Read more. |
| score | data gap | concerns | |
| SODIUM BICARBONATE | 2 | 80% | none identified |
| ALOE BARBADENSIS (ALOE VERA) LEAF JUICE EXTRACT organic aloe barbadensis (aloe vera) leaf juice (ORGANIC) | 0 | 100% | none identified |
| CITRUS MEDICA LIMONUM (LEMON) ESSENTIAL OIL organic citrus limonum (lemon) essential oil (ORGANIC) | 0 | 100% | none identified |
| LEMON MYRTLE OIL organic backhousia citriadora (lemon myrtle) essential oil (ORGANIC) | 0 | 100% | none identified |
| STEVIA REBAUDIANA (SWEETLEAF) EXTRACT stevia rebaudiana extract | 0 | 100% | none identified |
| CINNAMOMUM ZEYLANICUM (CINNAMON) LEAF OIL organic cinnamomum zeylanicum (cinnamon) leaf essential oil (ORGANIC) | 0 | 100% | none identified |
| XANTHAN GUM (NON GMO) | 0 | 94% | none identified |
| SEA SALT | 0 | 0% | innocuous |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more in vitro tests on mammalian cells show positive mutation results | SODIUM BICARBONATE, SEA SALT |
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show reproductive effects at moderate doses | SODIUM BICARBONATE | |
| One or more animal studies show reproductive effects at low doses | SEA SALT |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show brain and nervous system effects at high doses | SODIUM BICARBONATE | |
| One or more animal studies show brain and nervous system effects at moderate doses | SEA SALT |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show cardiovascular effects at moderate doses (low dose studies may be unavailable for this ingredient) | SODIUM BICARBONATE | |
| One or more animal studies show cardiovascular effects at very low doses | SEA SALT |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show skin irritation at moderate doses | SODIUM BICARBONATE | |
| One or more animal studies show skin irritation at very low doses | SEA SALT |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | SODIUM BICARBONATE | |
| Not assessed for safety in cosmetics by industry panel | CINNAMOMUM ZEYLANICUM (CINNAMON) LEAF OIL, XANTHAN GUM, STEVIA REBAUDIANA (SWEETLEAF) EXTRACT, LEMON MYRTLE OIL, CITRUS MEDICA LIMONUM (LEMON) ESSENTIAL OIL, ALOE BARBADENSIS (ALOE VERA) LEAF JUICE EXTRACT |
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | SODIUM BICARBONATE | |
| One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood | SEA SALT |
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