

Compact for Safe Cosmetics
|
Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: Neurotoxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes |
Ingredients from packaging: Active Ingredient: Sodium Monofluorophosphate = 0.76% Other Ingredients: Vegetable Glycerin, Aqua (Purified Water), Silica, Sodium Cocoyl Glutamate, Xylitol, Mentha Piperita (Peppermint) Oil, Ubiquinone (Coenzyme Q10), Tocopheryl Acetate (Vit. E), Aloe Barbadensis (Aloe Vera) Leaf Gel*, Bambusa Arundinacea (Bamboo) Stem Powder, Perilla Ocmyoides (Perilla) Seed Extract, Cellulose Gum, Sodium Bicarbonate, Sodium Magnesium Silicate, Calcium Carbonate, Methylsulfonylmethane (MSM), Sea Salt, Stevioside, Citrus Grandis (Grapefruit) Seed Extract *Certified Organic
Directions from packaging: Adults and children 2 years of age and older. Brush teeth thoroughly, preferably after each meal or at least twice a day, or as directed by a dentist or doctor. Instruct children under 6 years of age in good brushing and rinsing habits (to avoid swallowing). Supervise children as necessary until capable of using without supervision. Children under 2 years of age, consult a dentist or doctor. Children under 6, consult a dentist or doctor.
| score | data gap | concerns | |
| SILICA | 1 | 69% | Biochemical or cellular level changes |
| SODIUM MONOFLUOROPHOSPHATE | 6 | 69% | Developmental/reproductive toxicity, Violations, restrictions & warnings, Neurotoxicity, Organ system toxicity (non-reproductive), Occupational hazards |
| CITRUS GRANDIS (GRAPEFRUIT) SEED EXTRACT | 4 | 100% | Multiple, additive exposure sources, Contamination concerns (BENZETHONIUM CHLORIDE, METHYLPARABEN, TRICLOSAN) |
| TOCOPHERYL ACETATE | 4 | 81% | Allergies/immunotoxicity, Contamination concerns (HYDROQUINONE) |
| MENTHA PIPERITA (PEPPERMINT) OIL | 3 | 73% | Enhanced skin absorption, Contamination concerns (LIMONENE, MENTHOL, MENTHONE) |
| STEVIOSIDE | 2 | 84% | Organ system toxicity (non-reproductive), Occupational hazards |
| SODIUM BICARBONATE | 2 | 80% | none identified |
| VEGETABLE GLYCERIN | 1 | 98% | Organ system toxicity (non-reproductive) |
| PERILLA OCYMOIDES (BEEFSTEAK PLANT) SEED EXTRACT PERILLA OCMYOIDES (PERILLA) SEED EXTRACT | 1 | 97% | none identified |
| DIMETHYL SULFONE METHYLSULFONYLMETHANE (MSM) | 1 | 88% | none identified |
| XYLITOL | 1 | 88% | none identified |
| CALCIUM CARBONATE | 1 | 87% | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards |
| UBIQUINONE | 1 | 84% | none identified |
| CELLULOSE GUM | 1 | 80% | none identified |
| ALOE BARBADENSIS (ALOE VERA) LEAF GEL (ORGANIC) | 1 | 73% | none identified |
| BAMBUSA ARUNDINACEA (BAMBOO) STEM POWDER | 0 | 100% | none identified |
| SODIUM COCOYL GLUTAMATE | 0 | 100% | none identified |
| SODIUM MAGNESIUM SILICATE | 0 | 99% | none identified |
| SEA SALT | 0 | 0% | innocuous |
| WATER | 0 | 0% | innocuous |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show tumor formation at high doses | CELLULOSE GUM | |
| One or more in vitro tests non-mammalian cells show positive mutation results | PERILLA OCYMOIDES (BEEFSTEAK PLANT) SEED EXTRACT, MENTHA PIPERITA (PEPPERMINT) OIL | |
| One or more in vitro tests on mammalian cells show positive mutation results | TOCOPHERYL ACETATE, STEVIOSIDE, SODIUM MONOFLUOROPHOSPHATE, SODIUM BICARBONATE, SEA SALT |
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show reproductive effects at high doses | DIMETHYL SULFONE | |
| One or more animal studies show reproductive effects at moderate doses | UBIQUINONE, SODIUM BICARBONATE, CELLULOSE GUM | |
| One or more animal studies show reproductive effects at low doses | SEA SALT | |
| One or more animal studies show any effects at moderate doses | ALOE BARBADENSIS (ALOE VERA) LEAF GEL | |
| Human nervous system toxicant - moderate evidence | SODIUM MONOFLUOROPHOSPHATE |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | MENTHA PIPERITA (PEPPERMINT) OIL, ALOE BARBADENSIS (ALOE VERA) LEAF GEL | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | SODIUM MONOFLUOROPHOSPHATE |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show brain and nervous system effects at high doses | XYLITOL, UBIQUINONE, SODIUM BICARBONATE | |
| One or more animal studies show brain and nervous system effects at moderate doses | SEA SALT, MENTHA PIPERITA (PEPPERMINT) OIL | |
| Strong evidence of human neurotoxicity | SODIUM MONOFLUOROPHOSPHATE |
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Human skin toxicant - strong evidence | TOCOPHERYL ACETATE |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show sense organ effects at moderate doses (low dose studies may be unavailable for this ingredient) | products for use around the eyes, mouth, or lips | SILICA |
| One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient) | CELLULOSE GUM, MENTHA PIPERITA (PEPPERMINT) OIL, XYLITOL | |
| One or more animal studies show cardiovascular effects at moderate doses (low dose studies may be unavailable for this ingredient) | SODIUM BICARBONATE, TOCOPHERYL ACETATE, UBIQUINONE | |
| Limited evidence of cardiovascular or blood toxicity | VEGETABLE GLYCERIN | |
| Classified as very toxic or harmful | products for use around the mouth; products for use on the lips; products that may be aerosolized (airborne); products for use on skin | STEVIOSIDE |
| One or more animal studies show sense organ effects at very low doses | products for use around the eyes, mouth, or lips | CALCIUM CARBONATE |
| One or more animal studies show cardiovascular effects at very low doses | SEA SALT, SODIUM MONOFLUOROPHOSPHATE |
*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Designated as safe for general or specific, limited use in food | TOCOPHERYL ACETATE, SODIUM BICARBONATE, VEGETABLE GLYCERIN, XYLITOL, SEA SALT, MENTHA PIPERITA (PEPPERMINT) OIL, CELLULOSE GUM | |
| Used in food or as an additive with limited or no toxicity information available | CITRUS GRANDIS (GRAPEFRUIT) SEED EXTRACT | |
| Designated as safe for general or specific, limited use in food | CALCIUM CARBONATE |
*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Wildlife and environmental toxicity | STEVIOSIDE |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show skin irritation at low doses | CALCIUM CARBONATE | |
| One or more animal studies show skin irritation at moderate doses | SODIUM BICARBONATE | |
| One or more animal studies show skin irritation at very low doses | SEA SALT |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Missing safety data noted by cosmetic industry review | ALOE BARBADENSIS (ALOE VERA) LEAF GEL | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | TOCOPHERYL ACETATE, SODIUM MAGNESIUM SILICATE, SODIUM BICARBONATE, CELLULOSE GUM | |
| Not assessed for safety in cosmetics by industry panel | VEGETABLE GLYCERIN, XYLITOL, UBIQUINONE, STEVIOSIDE, SODIUM COCOYL GLUTAMATE, SODIUM MONOFLUOROPHOSPHATE, PERILLA OCYMOIDES (BEEFSTEAK PLANT) SEED EXTRACT, BAMBUSA ARUNDINACEA (BAMBOO) STEM POWDER, CALCIUM CARBONATE, CITRUS GRANDIS (GRAPEFRUIT) SEED EXTRACT, DIMETHYL SULFONE |
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to moderate doses | CALCIUM CARBONATE | |
| Allowed workplace exposures restricted to low doses | SODIUM MONOFLUOROPHOSPHATE | |
| Allowed workplace exposures restricted to very low doses | STEVIOSIDE |
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | XYLITOL, SODIUM BICARBONATE, CELLULOSE GUM | |
| One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood | UBIQUINONE | |
| One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood | SILICA, SEA SALT |
No items in basket.
Add this product
Looking for a product report that we don't have in Skin Deep? Sign up to enter it into the Skin Deep database and leave product reviews.
We always want Skin Deep to be free to the public, but delivering high-quality research costs time and money. Help by donating just the cost of a bar of soap or bottle of shampoo.
Stay informed with email updates on toxics in everyday products and how they can affect your health.
Find out more about the Campaign for Safe Cosmetics.