

Compact for Safe Cosmetics
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Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption |
Ingredients from packaging: Active Ingredients: Purified Water. Inactive Ingredients: Benzalkonium Chloride, Edetate Disodium, Sodium Chloride, Sodium Phosphate Dibasic, Sodium Phosphate Monobasic.
Directions from packaging: With nozzle applicator, without enclosed eye cup, Flush the affected eye as needed, controlling the rate of flow of solution by pressure on the bottle. Replace cap after using. With enclosed eye cup, Rinse cup with clean water immediately before each use. Avoid contamination of the rim and inside surfaces of the cup. Fill the cup half full and apply the cup to the affected eye(s), pressing tightly to prevent the escape of the liquid. Tilt the head backward. Open eyelids wide and rotate eyeball to ensure thorough bathing with the wash. Rinse cup with clean water after each use. Replace cap after using.
Warnings from packaging: Do not use, if solution changes color or becomes cloudy, with contact lenses. When using this product, avoid contamination-do not touch tip of container to any surface, replace cap after using, obtain immediate medical treatment for all open wounds in or near the eyes. Stop use and ask a doctor if, you experience eye pain, changes in vision, continued redness or irritation of the eye, condition worsens or persists for more than 72 hours. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
| score | data gap | concerns | |
| BENZALKONIUM CHLORIDE | 7 | 62% | Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| DISODIUM EDTA EDETATE DISODIUM | 3 | 78% | Neurotoxicity, Organ system toxicity (non-reproductive), Enhanced skin absorption |
| SODIUM PHOSPHATE | 1 | 89% | none identified |
| DISODIUM PHOSPHATE SODIUM PHOSPHATE DIBASIC | 1 | 86% | none identified |
| SODIUM CHLORIDE | 0 | 0% | innocuous |
| WATER (Active Ingredient) | 0 | 0% | innocuous |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more in vitro tests on mammalian cells show positive mutation results | BENZALKONIUM CHLORIDE, DISODIUM EDTA, SODIUM CHLORIDE |
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show reproductive effects at high doses | DISODIUM EDTA |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | BENZALKONIUM CHLORIDE | |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | BENZALKONIUM CHLORIDE | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit) | BENZALKONIUM CHLORIDE |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show brain and nervous system effects at moderate doses | DISODIUM PHOSPHATE | |
| One or more animal studies show brain and nervous system effects at low doses | DISODIUM EDTA |
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show endocrine system disruption at high doses | DISODIUM EDTA |
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Known human immune system toxicant | BENZALKONIUM CHLORIDE |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient) | SODIUM PHOSPHATE, DISODIUM PHOSPHATE | |
| One or more animal studies show sense organ effects at low doses | products for use around the eyes, mouth, or lips | SODIUM CHLORIDE |
| One or more animal studies show broad systemic effects at low doses | DISODIUM EDTA | |
| Possible human immune system toxicant | BENZALKONIUM CHLORIDE |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show skin irritation at moderate doses | DISODIUM PHOSPHATE, SODIUM CHLORIDE | |
| One or more animal studies show skin irritation at low doses | BENZALKONIUM CHLORIDE |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | DISODIUM EDTA | |
| Not assessed for safety in cosmetics by industry panel | DISODIUM PHOSPHATE, SODIUM PHOSPHATE |
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