Neutrogena Fresh Cooling Body Mist Sunblock, SPF 45 (old formulation) || Skin Deep: Cosmetic Safety Reviews

NEUTROGENA FRESH COOLING BODY MIST SUNBLOCK, SPF 45 (OLD FORMULATION)

last updated: 05/01/06 brand: Neutrogena by Johnson & Johnson

SCORE

	health hazard
	sun hazard

82%

data gap

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96% of sunscreen: SPF greater than 30s have lower concerns

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company conducts animal tests.

Sunscreen effectiveness* breakdown

0	UVB hazard/exposure score
5	UVA hazard/exposure score
1	sunscreen instability

*Note that the same active ingredient combination may score differently in two different products depending on the concentration of the ingredients and the mixture of inactive ingredients.

Active ingredient UV
blocking strength

Product total

AVOBENZONE (PARSOL 1789 | BUTYL METHOXYDIBENZOYLMETHANE) (3%)

HOMOSALATE (8%)

OCTISALATE (4%)

OCTOCRYLENE (2.35%)

OXYBENZONE (BENZOPHENONE-3) (5%)

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes

Note from EWG: Unlike many other kinds of personal care products, sunscreen can provide health benefits, protecting against the sun's cancer-causing UV radiation. More than one million cases of skin cancer are diagnosed in the U.S. every year. Health officials recommend wearing sunscreen as one of many important steps to minimize skin cancer risk. (more sun safety tips)

Ingredients from packaging: ACTIVE INGREDIENTS: AVOBENZONE 3.0%, HOMOSALATE 8.0%, OCTISALATE 4.0%, OCTOCRYLENE 2.35%, OXYBENZONE 5.0%. INACTIVE INGREDIENTS: SD-ALCOHOL 40-1 (67%), ISOBUTANE, DETHYLHEXYL 2, 6 - NAPTHALATE, TRISOLOXANE, DIMETHICONE, ACRYLATES/OCTYLACRYLACRYLAMIDE COPOLYMER, PPG - 5 - CETETH - 20, TOCOPHERYL ACETATE, ASCORBYL PALMITATE, RETINYL PALMITATE, CYCLOPENTASILOXANE, ACRYLATES/DIMETHICONE COPOLYMER, MENTHYL PCA, LAURYL PCA, PROPYLENE GLYCOL, ETHOXYDIGLYCOL, FRAGRANCE.

Directions from packaging: Apply 15-30 minutes before sun exposure. Hold can 6-8 inches away from body and apply liberally, ensuring complete coverage. Do not spray into face. Spray into hand and apply to the face. Use in well ventilated area. Reapply after swimming, excessive perspiration, towel drying, or extended sun exposure.

Warnings from packaging: For external use only. Not to be swallowed. Avoid contact with eyes. Do no spray directly on face. Discontinue use if sign of irritation or rash appear. Use on children under 6 months of age only with the advice of a physician. Keep this and all drugs our of the reach of children. In case of accidental ingestion, seek professional assistance or contact a Poison Control Care Center immediately. Caution: Flammable. Contents under pressure. Do not use near fire, heat or while smoking. Do not puncture or incinerate. Store at temperature below 120 degree F (48 degree C). Use only as directed. Intentional misuse by eliberately concentrating and inhaling the contents can be harmful or fatal.

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ingredients

	score	data gap	concerns
OXYBENZONE (BENZOPHENONE-3) (Active Ingredient)	9	55%	Developmental/reproductive toxicity, Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Enhanced skin absorption, Biochemical or cellular level changes
FRAGRANCE	8	100%	Neurotoxicity, Allergies/immunotoxicity, Miscellaneous
ISOBUTANE	6	79%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Contamination concerns (BUTADIENE), Occupational hazards
SD ALCOHOL 40	5	77%	Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Enhanced skin absorption, Contamination concerns (BRUCINE, T-BUTYL ALCOHOL, BRUCINE SULFATE, QUASSIN)
RETINYL PALMITATE	5	68%	Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
TOCOPHERYL ACETATE	4	81%	Allergies/immunotoxicity, Contamination concerns (HYDROQUINONE)
HOMOSALATE (Active Ingredient)	4	74%	Violations, restrictions & warnings, Enhanced skin absorption, Contamination concerns (SALICYLIC ACID, TRIMETHYLCYCLOHEXANOL)
OCTISALATE (Active Ingredient)	3	68%	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Enhanced skin absorption
PROPYLENE GLYCOL	4	60%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
PPG-5-CETETH-20	3	93%	Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
CYCLOPENTASILOXANE	2	79%	Persistence and bioaccumulation
DIMETHICONE	2	74%	Violations, restrictions & warnings
OCTOCRYLENE (Active Ingredient)	3	71%	Violations, restrictions & warnings, Biochemical or cellular level changes
TRISILOXANE TRISOLOXANE	1	89%	Persistence and bioaccumulation
ETHOXYDIGLYCOL	2	82%	Organ system toxicity (non-reproductive)
AVOBENZONE (PARSOL 1789 \| BUTYL METHOXYDIBENZOYLMETHANE) (Active Ingredient)	2	73%	Violations, restrictions & warnings, Contamination concerns (BENZOIC ACID, 4-T-BUTYLBENZOIC ACID, BENZALDEHYDE, P-ANISIC ACID, ACETOPHENONE, DIBENZOYLMETHANE)
ASCORBYL PALMITATE (VITAMIN C PALMITATE)	1	88%	none identified
ACRYLATES/ DIMETHICONE COPOLYMER	0	100%	none identified
ACRYLATES/ OCTYLACRYLAMIDE COPOLYMER ACRYLATES/OCTYLACRYLACRYLAMIDE COPOLYMER	0	100%	none identified
DIETHYLHEXYL 2,6-NAPHTHALATE DETHYLHEXYL-2,6-NAPTHALATE	0	100%	none identified
LAURYL PCA	0	100%	none identified
MENTHYL PCA	0	100%	none identified

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more in vitro tests non-mammalian cells show positive mutation results		OXYBENZONE (BENZOPHENONE-3), ETHOXYDIGLYCOL
One or more in vitro tests on mammalian cells show positive mutation results		TOCOPHERYL ACETATE
One or more animal studies show tumor formation at moderate doses		CYCLOPENTASILOXANE
One or more in vitro tests on mammalian cells show positive mutation results		PROPYLENE GLYCOL,
One or more in vitro tests on mammalian cells show positive mutation results		AVOBENZONE (PARSOL 1789 \| BUTYL METHOXYDIBENZOYLMETHANE)
Cancer - limited evidence		SD ALCOHOL 40, RETINYL PALMITATE

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive effects at high doses		ETHOXYDIGLYCOL
One or more animal studies show reproductive effects at moderate doses		PROPYLENE GLYCOL
Limited evidence of developmental toxicity		OXYBENZONE (BENZOPHENONE-3)
One or more animal studies show reproductive effects at low doses		RETINYL PALMITATE
Limited evidence of reproductive toxicity		SD ALCOHOL 40

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		PROPYLENE GLYCOL
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel		DIMETHICONE
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		RETINYL PALMITATE, OCTOCRYLENE, OCTISALATE, OXYBENZONE (BENZOPHENONE-3), HOMOSALATE, AVOBENZONE (PARSOL 1789 \| BUTYL METHOXYDIBENZOYLMETHANE)

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study		SD ALCOHOL 40
Moderate evidence of human neurotoxicity		FRAGRANCE
One or more animal studies show brain and nervous system effects at high doses		OXYBENZONE (BENZOPHENONE-3), PROPYLENE GLYCOL, RETINYL PALMITATE, ETHOXYDIGLYCOL
One or more animal studies show any effects at moderate doses		CYCLOPENTASILOXANE

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more studies show weak endocrine disruption		HOMOSALATE
One or more animal studies show endocrine disruption at moderate doses		CYCLOPENTASILOXANE
Human any disruptor - moderate evidence		OXYBENZONE (BENZOPHENONE-3)

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Limited evidence of skin and immune system toxicity		PROPYLENE GLYCOL
One or more human case studies show possible immune effects		OCTISALATE
Associated with immunotoxicity		AVOBENZONE (PARSOL 1789 \| BUTYL METHOXYDIBENZOYLMETHANE)
Human skin toxicant - strong evidence		TOCOPHERYL ACETATE, ISOBUTANE
Possible human photoallergenic toxicant		OXYBENZONE (BENZOPHENONE-3)
Known human immune system toxicant		FRAGRANCE

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not suspected to be bioaccumulative		ISOBUTANE
Ingredient is suspected or measured to accumulate in people		OXYBENZONE (BENZOPHENONE-3)
Persistent, bioaccumulative in wildlife		TRISILOXANE
Found to be persistent and bioaccumulative in wildlife		OCTOCRYLENE
Persistent, bioaccumulative in wildlife		CYCLOPENTASILOXANE

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient)		CYCLOPENTASILOXANE, OCTOCRYLENE
Classified as expected to be toxic or harmful		ISOBUTANE
One or more animal studies show cardiovascular effects at moderate doses (low dose studies may be unavailable for this ingredient)		OXYBENZONE (BENZOPHENONE-3)
One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient)		ASCORBYL PALMITATE (VITAMIN C PALMITATE)
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		OCTISALATE, TOCOPHERYL ACETATE
Limited evidence of skin toxicity		RETINYL PALMITATE, SD ALCOHOL 40, ETHOXYDIGLYCOL
Limited evidence of respiratory toxicity	products that may be aerosolized (airborne)	PROPYLENE GLYCOL

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Occupational hazards related to handling		SD ALCOHOL 40, ISOBUTANE
Ingredient not fully labeled - identity unknown		FRAGRANCE

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Designated as safe for general or specific, limited use in food		TOCOPHERYL ACETATE, RETINYL PALMITATE, DIMETHICONE, PROPYLENE GLYCOL, ISOBUTANE, ETHOXYDIGLYCOL, ASCORBYL PALMITATE (VITAMIN C PALMITATE)
Used in food or as an additive with limited or no toxicity information available		SD ALCOHOL 40, ISOBUTANE

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not suspected to be an environmental toxin		ISOBUTANE
Wildlife and environmental toxicity		OXYBENZONE (BENZOPHENONE-3), OCTOCRYLENE

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not likely to be a skin irritant in humans		OXYBENZONE (BENZOPHENONE-3)
One or more animal studies show skin irritation at moderate doses		ETHOXYDIGLYCOL, CYCLOPENTASILOXANE
One or more animal studies show skin irritation at low doses		OCTISALATE
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	ISOBUTANE
Classified as skin irritant		PROPYLENE GLYCOL

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Insufficient data to determine safety		SD ALCOHOL 40
Safety assessment was based on related chemical		PPG-5-CETETH-20, PROPYLENE GLYCOL
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		RETINYL PALMITATE, TOCOPHERYL ACETATE, ISOBUTANE, OXYBENZONE (BENZOPHENONE-3), DIMETHICONE, ETHOXYDIGLYCOL, ASCORBYL PALMITATE (VITAMIN C PALMITATE)
Not assessed for safety in cosmetics by industry panel		TRISILOXANE, PPG-5-CETETH-20, OCTOCRYLENE, OCTISALATE, MENTHYL PCA, LAURYL PCA, HOMOSALATE, FRAGRANCE, DIETHYLHEXYL 2,6-NAPHTHALATE, CYCLOPENTASILOXANE, AVOBENZONE (PARSOL 1789 \| BUTYL METHOXYDIBENZOYLMETHANE), ACRYLATES/ OCTYLACRYLAMIDE COPOLYMER, ACRYLATES/ DIMETHICONE COPOLYMER

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to high doses		ISOBUTANE

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Does not produces excess reactive oxygen species or other harmful biochemical changes.		OCTISALATE
Produces excess reactive oxygen species that can interfere with cellular signaling, cause mutations, lead to cell death and may be implicated in cardiovascular disease.		RETINYL PALMITATE, OCTOCRYLENE, OXYBENZONE (BENZOPHENONE-3)
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		CYCLOPENTASILOXANE, PROPYLENE GLYCOL