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Compact for Safe Cosmetics
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Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards |
Ingredients from packaging: Water, Ethoxydiglycol, C11-15 Pareth-3, Vegetable Fatty Acid, Aminomethyl Propanol, Oleyl Alcohol, Fragrance, Sodium Sulfite, Erythorbic Acid, Trisodium EDTA, Polyquaternium-22, Panthenol, Tocopheryl Acetate, Aloe Vera Extract, Chamomile Extract, P-Phenylenediamine, M-Aminophenol, Resorcinol, 1-Naphthol, 4-Chlororesorcinol, M-Phenylenediamine, Phenyl Methyl Pyrazolone. Color Developer: Water, Hydrogen Peroxide.
Warnings from packaging: This product contains ingredients which may cause skin irritation on certain individuals and a preliminary test according to accompanying directions should first be made. This product must not be used for dyeing the eyelashes or eyebrows - to do so may cause blindness. Do not use if you have skin depigmentation problems such as white patches on your skin (a condition called Vitiligo), or if you have a family history of skin depigmentation problems, as an allergic reaction or skin irritation may cause loss of skin pigment.
| score | data gap | concerns | |
| P-PHENYLENEDIAMINE | 10 | 52% | Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| RESORCINOL | 10 | 52% | Cancer, Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| FRAGRANCE | 8 | 100% | Neurotoxicity, Allergies/immunotoxicity, Miscellaneous |
| M-PHENYLENEDIAMINE | 7 | 63% | Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (NITROSAMINES), Occupational hazards |
| 1-NAPHTHOL | 8 | 60% | Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| 4-CHLORORESORCINOL | 5 | 68% | Cancer, Violations, restrictions & warnings, Neurotoxicity, Allergies/immunotoxicity |
| HYDROGEN PEROXIDE | 3 | 65% | Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| M-AMINOPHENOL | 6 | 65% | Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Occupational hazards |
| PHENYL METHYL PYRAZOLONE | 5 | 68% | Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity |
| TOCOPHERYL ACETATE | 4 | 81% | Allergies/immunotoxicity, Contamination concerns (HYDROQUINONE) |
| VEGETABLE FATTY ACID | 4 | 72% | Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards |
| SODIUM SULFITE | 3 | 87% | Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive) |
| PANTHENOL | 2 | 88% | Multiple, additive exposure sources |
| ETHOXYDIGLYCOL | 2 | 82% | Organ system toxicity (non-reproductive) |
| AMINOMETHYL PROPANOL | 2 | 71% | Irritation (skin, eyes, or lungs), Contamination concerns (NITROSAMINES, OXAZOLIDINE) |
| C11-15 PARETH-3 | 1 | 88% | none identified |
| ERYTHORBIC ACID | 1 | 87% | none identified |
| OLEYL ALCOHOL | 1 | 87% | Irritation (skin, eyes, or lungs) |
| TRISODIUM EDTA | 1 | 86% | Enhanced skin absorption |
| ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT CHAMOMILE EXTRACT | 1 | 80% | Enhanced skin absorption |
| ALOE BARBADENSIS (ALOE VERA) LEAF EXTRACT ALOE VERA EXTRACT | 1 | 75% | none identified |
| POLYQUATERNIUM-22 | 0 | 100% | none identified |
| WATER | 0 | 0% | innocuous |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more in vitro tests non-mammalian cells show positive mutation results | ETHOXYDIGLYCOL | |
| One or more in vitro tests on mammalian cells show positive mutation results | TOCOPHERYL ACETATE, SODIUM SULFITE, ERYTHORBIC ACID | |
| Cancer - limited evidence | PHENYL METHYL PYRAZOLONE, M-AMINOPHENOL, 4-CHLORORESORCINOL, 1-NAPHTHOL | |
| Mutagen - limited evidence | M-PHENYLENEDIAMINE | |
| Cancer - not classifiable/not likely to be human carcinogen | RESORCINOL, P-PHENYLENEDIAMINE, HYDROGEN PEROXIDE |
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show reproductive effects at high doses | M-AMINOPHENOL, M-PHENYLENEDIAMINE, PHENYL METHYL PYRAZOLONE, ETHOXYDIGLYCOL, 4-CHLORORESORCINOL | |
| One or more animal studies show reproductive effects at moderate doses | 1-NAPHTHOL | |
| Human nervous system toxicant - moderate evidence | P-PHENYLENEDIAMINE |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | M-PHENYLENEDIAMINE, AMINOMETHYL PROPANOL, 4-CHLORORESORCINOL, RESORCINOL, ALOE BARBADENSIS (ALOE VERA) LEAF EXTRACT, PHENYL METHYL PYRAZOLONE, P-PHENYLENEDIAMINE, M-PHENYLENEDIAMINE, M-AMINOPHENOL | |
| Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel | PHENYL METHYL PYRAZOLONE, P-PHENYLENEDIAMINE | |
| Determined safe for use in cosmetics, subject to concentration or use limitations - any | 1-NAPHTHOL | |
| Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel | M-AMINOPHENOL, M-PHENYLENEDIAMINE | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | VEGETABLE FATTY ACID | |
| Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel | 4-CHLORORESORCINOL, 1-NAPHTHOL | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | P-PHENYLENEDIAMINE, RESORCINOL |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show brain and nervous system effects at high doses | 1-NAPHTHOL, PHENYL METHYL PYRAZOLONE, ETHOXYDIGLYCOL | |
| One or more animal studies show brain and nervous system effects at moderate doses | RESORCINOL, M-PHENYLENEDIAMINE, M-AMINOPHENOL, ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT | |
| One or more animal studies show brain and nervous system effects at low doses | SODIUM SULFITE | |
| One or more animal studies show brain and nervous system effects at moderate doses | AMINOMETHYL PROPANOL | |
| One or more animal studies show brain and nervous system effects at very low doses | HYDROGEN PEROXIDE | |
| One or more animal studies show brain and nervous system effects at low doses | 4-CHLORORESORCINOL | |
| Strong evidence of human neurotoxicity | P-PHENYLENEDIAMINE | |
| Moderate evidence of human neurotoxicity | FRAGRANCE |
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show endocrine system disruption at high doses | P-PHENYLENEDIAMINE, HYDROGEN PEROXIDE, ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT | |
| One or more animal studies show endocrine disruption at moderate doses | 1-NAPHTHOL | |
| Human any disruptor - strong evidence | RESORCINOL |
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Human immune system toxicant - moderate evidence | VEGETABLE FATTY ACID, SODIUM SULFITE | |
| Human skin toxicant - strong evidence | PHENYL METHYL PYRAZOLONE, TOCOPHERYL ACETATE, M-PHENYLENEDIAMINE, M-AMINOPHENOL, 4-CHLORORESORCINOL, 1-NAPHTHOL | |
| Known human immune system toxicant | P-PHENYLENEDIAMINE, RESORCINOL, FRAGRANCE |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient) | ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT, C11-15 PARETH-3, PANTHENOL, ERYTHORBIC ACID, AMINOMETHYL PROPANOL | |
| One or more animal studies show liver effects at moderate doses (low dose studies may be unavailable for this ingredient) | PHENYL METHYL PYRAZOLONE, TRISODIUM EDTA, TOCOPHERYL ACETATE | |
| Limited evidence of cardiovascular or blood toxicity | ETHOXYDIGLYCOL | |
| One or more animal studies show broad systemic effects at low doses | M-PHENYLENEDIAMINE, RESORCINOL | |
| One or more animal studies show gastrointestinal effects at very low doses | HYDROGEN PEROXIDE | |
| Possible human immune system toxicant | VEGETABLE FATTY ACID, SODIUM SULFITE | |
| Known human lung and skin toxicant | products that may be aerosolized (airborne); products for use on skin | 1-NAPHTHOL |
| Known human respiratory toxicant | P-PHENYLENEDIAMINE |
*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Occupational hazards related to handling | HYDROGEN PEROXIDE | |
| Ingredient not fully labeled - identity unknown | FRAGRANCE |
*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Designated as safe for general or specific, limited use in food | TOCOPHERYL ACETATE, SODIUM SULFITE, RESORCINOL, HYDROGEN PEROXIDE, ETHOXYDIGLYCOL, ERYTHORBIC ACID, ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT | |
| Used in food or as an additive with limited or no toxicity information available | PANTHENOL |
*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Wildlife and environmental toxicity | RESORCINOL, M-PHENYLENEDIAMINE, P-PHENYLENEDIAMINE, M-AMINOPHENOL, AMINOMETHYL PROPANOL |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show skin irritation at high doses | SODIUM SULFITE | |
| One or more animal studies show skin irritation at moderate doses | C11-15 PARETH-3, M-AMINOPHENOL, ETHOXYDIGLYCOL, 4-CHLORORESORCINOL, ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT | |
| Human skin irritant - moderate evidence | HYDROGEN PEROXIDE | |
| Human any irritant - strong evidence | products for use around the eyes, on the skin, or may be aerosolized (airborne) | OLEYL ALCOHOL |
| Classified as irritant | RESORCINOL, P-PHENYLENEDIAMINE, M-PHENYLENEDIAMINE, AMINOMETHYL PROPANOL, 1-NAPHTHOL |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Insufficient data to determine safety | PHENYL METHYL PYRAZOLONE | |
| Missing safety data noted by cosmetic industry review | PHENYL METHYL PYRAZOLONE | |
| Insufficient data to determine safety | 1-NAPHTHOL, M-AMINOPHENOL, M-PHENYLENEDIAMINE, P-PHENYLENEDIAMINE | |
| Missing safety data noted by cosmetic industry review | P-PHENYLENEDIAMINE, ALOE BARBADENSIS (ALOE VERA) LEAF EXTRACT, M-PHENYLENEDIAMINE, M-AMINOPHENOL | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | TRISODIUM EDTA | |
| Missing safety data noted by cosmetic industry review | 1-NAPHTHOL | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | SODIUM SULFITE, PANTHENOL, TOCOPHERYL ACETATE, RESORCINOL, PHENYL METHYL PYRAZOLONE, P-PHENYLENEDIAMINE, ETHOXYDIGLYCOL, M-AMINOPHENOL, ERYTHORBIC ACID | |
| Not assessed for safety in cosmetics by industry panel | POLYQUATERNIUM-22, VEGETABLE FATTY ACID, C11-15 PARETH-3 | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | 1-NAPHTHOL, 4-CHLORORESORCINOL, OLEYL ALCOHOL, ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT | |
| Not assessed for safety in cosmetics by industry panel | HYDROGEN PEROXIDE, FRAGRANCE, ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT |
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to moderate doses | VEGETABLE FATTY ACID | |
| Allowed workplace exposures restricted to low doses | HYDROGEN PEROXIDE, M-AMINOPHENOL, RESORCINOL | |
| Allowed workplace exposures restricted to very low doses | M-PHENYLENEDIAMINE, P-PHENYLENEDIAMINE | |
| Allowed workplace exposures restricted to low doses | 1-NAPHTHOL |
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | HYDROGEN PEROXIDE |
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