

Compact for Safe Cosmetics
|
Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes |
Ingredients from packaging: Active Ingredients: Salicylic Acid (2%) (Acne Treatment)Inactive Ingredients: Allantoin, Aloe Vera, Burdock Extract, Calendula Extract, Capryloyl Glycine, Chamomile Extract, Cinnamon Extract, Coneflower Extract, Water (Deionized), Diazolidinyl Urea, Fragrance, Methylglycine, Methylparaben, Propylene Glycol, Propylparaben, SD Alcohol 40, Sodium Citrate, Tocopheryl Acetate (Vitamin E), Triethanolamine, Willow Bark Extract, Witch Hazel
Directions from packaging: Cleanse skin thoroughly before applying. Spray the entire affected area with a thin layer 1 to 3 times daily. Because excessive drying of the skin may occur, gradually increase to 2 or 3 times daily if needed or as directed by a doctor. Leave on all day or night. If bothersome dryness or peeling occurs, reduce usage to once a day or every other day. To use on face, spray onto cotton ball and brush onto skin.
Warnings from packaging: WarningsFor external use only. When using this product Using other topical acne drugs at the same time or right after use of this product may increase dryness or irritation of the skin. If this occurs, only one drug should be used unless directed by a doctor. Do not spray directly on or near face. Avoid contact with eyes, lips and mouth. Keep out of reach of children.If swallowed, get medical help or contact a Poison Control Center right away.
| score | data gap | concerns | |
| METHYLPARABEN | 10 | 63% | Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes |
| FRAGRANCE | 8 | 100% | Neurotoxicity, Allergies/immunotoxicity, Miscellaneous |
| SALICYLIC ACID (Active Ingredient) | 7 | 66% | Violations, restrictions & warnings, Neurotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Enhanced skin absorption |
| DIAZOLIDINYL UREA | 6 | 59% | Allergies/immunotoxicity, Contamination concerns (FORMALDEHYDE) |
| TRIETHANOLAMINE | 6 | 58% | Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (NITROSAMINES), Occupational hazards |
| SD ALCOHOL 40 | 5 | 77% | Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Enhanced skin absorption, Contamination concerns (BRUCINE, T-BUTYL ALCOHOL, BRUCINE SULFATE, QUASSIN) |
| PROPYLPARABEN | 5 | 71% | Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive) |
| TOCOPHERYL ACETATE | 4 | 81% | Allergies/immunotoxicity, Contamination concerns (HYDROQUINONE) |
| PROPYLENE GLYCOL | 4 | 60% | Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption |
| HAMAMELIS VIRGINIANA (WITCH HAZEL) | 1 | 97% | none identified |
| SALIX ALBA (WHITE WILLOW) BARK EXTRACT | 1 | 93% | Organ system toxicity (non-reproductive) |
| CALENDULA OFFICINALIS (POT MARIGOLD) FLOWER EXTRACT CALENDULA EXTRACT | 1 | 91% | none identified |
| ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT CHAMOMILE EXTRACT | 1 | 80% | Enhanced skin absorption |
| ALOE BARBADENSIS (ALOE VERA) | 1 | 72% | none identified |
| ARCTIUM MINUS (BURDOCK) EXTRACT | 0 | 100% | none identified |
| CAPRYLOYL GLYCINE | 0 | 100% | none identified |
| CINNAMONUM CASSIA (CINNAMON) BARK EXTRACT CINNAMON EXTRACT | 0 | 100% | none identified |
| CONE FLOWER EXTRACT | 0 | 100% | none identified |
| ALLANTOIN | 0 | 94% | none identified |
| SARCOSINE METHYLGLYCINE | 0 | 94% | none identified |
| SODIUM CITRATE | 0 | 94% | none identified |
| WATER | 0 | 0% | innocuous |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more in vitro tests non-mammalian cells show positive mutation results | HAMAMELIS VIRGINIANA (WITCH HAZEL), CALENDULA OFFICINALIS (POT MARIGOLD) FLOWER EXTRACT, ALOE BARBADENSIS (ALOE VERA) | |
| One or more in vitro tests on mammalian cells show positive mutation results | TOCOPHERYL ACETATE, PROPYLPARABEN, PROPYLENE GLYCOL, METHYLPARABEN, DIAZOLIDINYL UREA | |
| Cancer - not classifiable/not likely to be human carcinogen | SALICYLIC ACID | |
| Cancer - limited evidence | SD ALCOHOL 40 | |
| Cancer - not classifiable/not likely to be human carcinogen | TRIETHANOLAMINE |
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show reproductive effects at moderate doses | ALOE BARBADENSIS (ALOE VERA) | |
| One or more animal studies show reproductive effects at moderate doses | SALICYLIC ACID, PROPYLENE GLYCOL | |
| One or more animal studies show any effects at low doses | PROPYLPARABEN | |
| Limited evidence of reproductive toxicity | SD ALCOHOL 40 |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | TRIETHANOLAMINE, SALICYLIC ACID, PROPYLENE GLYCOL, DIAZOLIDINYL UREA | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | SALICYLIC ACID | |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | ALOE BARBADENSIS (ALOE VERA) | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in cosmetics (concentration limit) | SALICYLIC ACID | |
| Violation of government restrictions - Banned or found unsafe for use in cosmetics | METHYLPARABEN |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Moderate evidence of human neurotoxicity | FRAGRANCE | |
| One or more animal studies show brain and nervous system effects at low doses | SALICYLIC ACID | |
| One or more animal studies show brain and nervous system effects at moderate doses | ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT, METHYLPARABEN | |
| One or more animal studies show brain and nervous system effects at high doses | DIAZOLIDINYL UREA, PROPYLENE GLYCOL | |
| nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study | SD ALCOHOL 40 |
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Human any disruptor - strong evidence | METHYLPARABEN, PROPYLPARABEN | |
| One or more animal studies show endocrine system disruption at high doses | ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT, DIAZOLIDINYL UREA, TRIETHANOLAMINE |
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Limited evidence of skin and immune system toxicity | PROPYLENE GLYCOL | |
| Human skin toxicant - strong evidence | TOCOPHERYL ACETATE | |
| Known human immune system toxicant | TRIETHANOLAMINE | |
| Human skin toxicant - strong evidence | METHYLPARABEN, PROPYLPARABEN | |
| Known human immune system toxicant | FRAGRANCE, DIAZOLIDINYL UREA |
*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not suspected to be bioaccumulative | TRIETHANOLAMINE | |
| Persistent, bioaccumulative in wildlife | SALICYLIC ACID |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient) | DIAZOLIDINYL UREA | |
| One or more animal studies show respiratory effects at moderate doses (low dose studies may be unavailable for this ingredient) | products that may be aerosolized (airborne) | ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT |
| One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient) | TOCOPHERYL ACETATE | |
| Limited evidence of sense organ toxicity | PROPYLPARABEN | |
| One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient) | CALENDULA OFFICINALIS (POT MARIGOLD) FLOWER EXTRACT | |
| Limited evidence of gastrointestinal or liver toxicity | SD ALCOHOL 40 | |
| One or more animal studies show metabolic effects at low doses | SALICYLIC ACID | |
| Possible human immune system toxicant | TRIETHANOLAMINE | |
| Limited evidence of respiratory toxicity | products that may be aerosolized (airborne) | PROPYLENE GLYCOL |
| Known human any toxicant | METHYLPARABEN | |
| Limited evidence of any toxicity | SALIX ALBA (WHITE WILLOW) BARK EXTRACT |
*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Occupational hazards related to handling | SD ALCOHOL 40 | |
| Ingredient not fully labeled - identity unknown | FRAGRANCE |
*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Designated as safe for general or specific, limited use in food | SALICYLIC ACID, SODIUM CITRATE, TOCOPHERYL ACETATE, TRIETHANOLAMINE, PROPYLPARABEN, METHYLPARABEN, PROPYLENE GLYCOL, ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT, ALOE BARBADENSIS (ALOE VERA) | |
| Used in food or as an additive with limited or no toxicity information available | SD ALCOHOL 40, SALICYLIC ACID |
*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not suspected to be an environmental toxin | TRIETHANOLAMINE | |
| Wildlife and environmental toxicity | PROPYLPARABEN |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show skin irritation at moderate doses | SALICYLIC ACID, ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT | |
| One or more animal studies show skin irritation at low doses | METHYLPARABEN | |
| One or more animal studies show skin irritation at very low doses | TRIETHANOLAMINE | |
| Classified as skin irritant | PROPYLENE GLYCOL |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Safety assessment was based on related chemical | PROPYLENE GLYCOL | |
| Insufficient data to determine safety | CALENDULA OFFICINALIS (POT MARIGOLD) FLOWER EXTRACT, SD ALCOHOL 40 | |
| Missing safety data noted by cosmetic industry review | ALOE BARBADENSIS (ALOE VERA) | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | TOCOPHERYL ACETATE, PROPYLPARABEN, METHYLPARABEN, ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT | |
| Not assessed for safety in cosmetics by industry panel | CONE FLOWER EXTRACT, SODIUM CITRATE, SARCOSINE, HAMAMELIS VIRGINIANA (WITCH HAZEL), FRAGRANCE, CINNAMONUM CASSIA (CINNAMON) BARK EXTRACT, CAPRYLOYL GLYCINE, ARCTIUM MINUS (BURDOCK) EXTRACT, ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT, SALIX ALBA (WHITE WILLOW) BARK EXTRACT, ALLANTOIN |
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to moderate doses | TRIETHANOLAMINE |
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show blood sugar changes at high doses where the human health implications are not yet well understood | PROPYLENE GLYCOL | |
| Interferes with gene expresion | METHYLPARABEN |
No items in basket.
Add this product
Looking for a product report that we don't have in Skin Deep? Sign up to enter it into the Skin Deep database and leave product reviews.
We always want Skin Deep to be free to the public, but delivering high-quality research costs time and money. Help by donating just the cost of a bar of soap or bottle of shampoo.
Stay informed with email updates on toxics in everyday products and how they can affect your health.
'I just wanted to let you know how much Skin Deep has changed my daughter's (and my) life.'
—Melissa M., Michigan