Orly Nail Lacquer, Haute Red || Skin Deep: Cosmetic Safety Reviews

ORLY NAIL LACQUER, HAUTE RED

last updated: 03/15/09 brand: Orly by Orly International, Inc.

SCORE

high hazard (out of 10)

82%

data gap

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COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company does not test on animals.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes

Ingredients from packaging: Toluene, Butyl Acetate, Ethyl Acetate, Nitrocellulose, Tosylamide/Formaldehyde Resin, Isopropyl Alcohol, Trimethyl Pentanyl Diisobutyrate, Triphenyl Phosphate, Camphor, Stearalkonium Bentonite, Stearalkonium Hectorite, Benzophenone 1, May Contain:, Acrylates Copolymer, Adipic Acid/Neopentyl Glycol/Trimellitic Anhydride Copolymer, Alcohol Denat., Blue (CI 42090), Citric Acid, Dibutyl Adipate, Ethyl Tosylamide, Equisetum Arvense (Horsetail) Extract, Guanine (CI 75170), Panax Ginseng Root Extract, Phthalic Anhydride/Trimellitic Anhydride/Glycols Copolymer, Polyvinyl Butyral, Silica, Styrene/Acrylates, Copolymer, Sucrose Acetate Isobutyrate, Violet 2 (CI 60730), Mica (CI 77019), Black Iron Oxide (CI 77499), Ferric Ammonium Ferrocyanide (CI 77520), D&C Red 30 Lake (CI 73360), Polyethylene Teraphthalate

Directions from packaging: Shake well. Apply 2 coats.

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ingredients

	score	data gap	concerns
TOLUENE	10	54%	Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Neurotoxicity, Allergies/immunotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (BENZENE), Occupational hazards
SILICA	1	69%	Biochemical or cellular level changes
TRIPHENYL PHOSPHATE	7	64%	Developmental/reproductive toxicity, Neurotoxicity, Allergies/immunotoxicity, Occupational hazards
FERRIC AMMONIUM FERROCYANIDE	5	75%	Developmental/reproductive toxicity, Neurotoxicity, Endocrine disruption, Organ system toxicity (non-reproductive), Occupational hazards
EXT D&C VIOLET 2 VIOLET 2 (CI 60730)	5	73%	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity
BENZOPHENONE-1	5	79%	Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
ETHYL ACETATE	4	78%	Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
D&C RED 30 LAKE	4	72%	Developmental/reproductive toxicity, Neurotoxicity, Persistence and bioaccumulation
UNSPECIFIED COLOR BLUE (CI 42090)	4	100%	Miscellaneous
UNSPECIFIED POLYMER COPOLYMER	4	100%	Miscellaneous
SD ALCOHOL 1 ALCOHOL DENAT.	4	77%	Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Enhanced skin absorption
ISOPROPYL ALCOHOL	4	72%	Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
TOSYLAMIDE/ FORMALDEHYDE RESIN	4	72%	Allergies/immunotoxicity
CAMPHOR	4	69%	Violations, restrictions & warnings, Neurotoxicity, Organ system toxicity (non-reproductive), Occupational hazards
ACRYLATES COPOLYMER	3	75%	Contamination concerns (METHACRYLIC ACID, ACRYLIC ACID, 2-ETHYLHEXYL ACRYLATE)
MICA	3	75%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Occupational hazards
STYRENE/ ACRYLATES COPOLYMER	3	75%	Contamination concerns (METHACRYLIC ACID, ACRYLIC ACID, 2-ETHYLHEXYL ACRYLATE)
CI 77499	3	74%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Occupational hazards, Biochemical or cellular level changes
CITRIC ACID	2	72%	Violations, restrictions & warnings
TRIMETHYL PENTANYL DIISOBUTYRATE	2	93%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive)
SUCROSE ACETATE ISOBUTYRATE	1	86%	none identified
NITROCELLULOSE	1	94%	Organ system toxicity (non-reproductive)
POLYETHYLENE TEREPHTHALATE POLYETHYLENE TERAPHTHALATE	1	93%	Organ system toxicity (non-reproductive)
STEARALKONIUM HECTORITE	1	93%	Contamination concerns (NITROSAMINES, FREE AMINES)
PANAX GINSENG (GINSENG) ROOT EXTRACT PANAX GINSENG ROOT EXTRACT	1	91%	none identified
POLYVINYL BUTYRAL	0	89%	none identified
GUANINE	1	88%	none identified
DIBUTYL ADIPATE	1	83%	none identified
BUTYL ACETATE	1	78%	Irritation (skin, eyes, or lungs), Occupational hazards
EQUISETUM ARVENSE (HORSETAIL) EXTRACT	0	100%	none identified
PHTHALIC ANHYDRIDE/ TRIMELLITIC ANHYDRIDE/ GLYCOLS COPOLYMER	0	100%	none identified
STEARALKONIUM BENTONITE	0	100%	none identified
ADIPIC ACID/ NEOPENTYL GLYCOL/ TRIMELLITIC ANHYDRIDE COPOLYMER	0	94%	none identified
ETHYL TOSYLAMIDE	0	94%	none identified

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show tumor formation at moderate doses		POLYETHYLENE TEREPHTHALATE
One or more in vitro tests on mammalian cells show positive mutation results		DIBUTYL ADIPATE, GUANINE, ETHYL ACETATE, CAMPHOR
Cancer - limited evidence		SD ALCOHOL 1, EXT D&C VIOLET 2
Cancer - not classifiable/not likely to be human carcinogen		CI 77499, TOLUENE, ISOPROPYL ALCOHOL

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive effects at high doses		DIBUTYL ADIPATE
Limited evidence of developmental toxicity		ISOPROPYL ALCOHOL
Human nervous system toxicant - moderate evidence		TRIPHENYL PHOSPHATE, FERRIC AMMONIUM FERROCYANIDE, ETHYL ACETATE, D&C RED 30 LAKE
Limited evidence of reproductive toxicity		SD ALCOHOL 1
Possible human developmental toxicant		TOLUENE

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		STYRENE/ ACRYLATES COPOLYMER, TOLUENE, EXT D&C VIOLET 2, ACRYLATES COPOLYMER, D&C RED 30 LAKE
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel		EXT D&C VIOLET 2
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		CITRIC ACID, CAMPHOR
Violation of industry recommendations - Unsafe for use in cosmetics		TOLUENE

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study		SD ALCOHOL 1, BUTYL ACETATE
One or more animal studies show brain and nervous system effects at high doses		SUCROSE ACETATE ISOBUTYRATE
One or more animal studies show brain and nervous system effects at low doses		CAMPHOR
One or more animal studies show brain and nervous system effects at high doses		BENZOPHENONE-1
Strong evidence of human neurotoxicity		TOLUENE, TRIPHENYL PHOSPHATE, FERRIC AMMONIUM FERROCYANIDE, D&C RED 30 LAKE, ETHYL ACETATE, ISOPROPYL ALCOHOL

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Limited evidence of endocrine disruption		FERRIC AMMONIUM FERROCYANIDE
Human any disruptor - strong evidence		BENZOPHENONE-1

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show gastrointestinal effects at moderate doses		MICA
Limited evidence of immune system toxicity		TOLUENE
Human skin toxicant - strong evidence		EXT D&C VIOLET 2, BENZOPHENONE-1
Known human immune system toxicant		TRIPHENYL PHOSPHATE, TOSYLAMIDE/ FORMALDEHYDE RESIN

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not suspected to be bioaccumulative		TOLUENE, POLYETHYLENE TEREPHTHALATE, ISOPROPYL ALCOHOL
Persistent, bioaccumulative in wildlife		D&C RED 30 LAKE
Not suspected to be persistent		TRIMETHYL PENTANYL DIISOBUTYRATE
Persistent, bioaccumulative in wildlife and humans		MICA, CI 77499

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Classified as expected to be toxic or harmful		POLYETHYLENE TEREPHTHALATE, TRIMETHYL PENTANYL DIISOBUTYRATE
One or more animal studies show metabolic effects at high doses (low dose studies may be unavailable for this ingredient)		SILICA
Classified as expected to be toxic or harmful		NITROCELLULOSE
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient)		PANAX GINSENG (GINSENG) ROOT EXTRACT, SUCROSE ACETATE ISOBUTYRATE, DIBUTYL ADIPATE
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		TRIPHENYL PHOSPHATE
Limited evidence of sense organ toxicity		ISOPROPYL ALCOHOL
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		CITRIC ACID
Limited evidence of sense organ toxicity		ETHYL ACETATE, CI 77499, FERRIC AMMONIUM FERROCYANIDE, SD ALCOHOL 1
One or more animal studies show gastrointestinal effects at low doses		CAMPHOR, BENZOPHENONE-1
Possible human respiratory toxicant		MICA
Known human respiratory toxicant		TOLUENE

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Occupational hazards related to handling		SD ALCOHOL 1, TOLUENE, ETHYL ACETATE, ISOPROPYL ALCOHOL, BUTYL ACETATE
Ingredient not fully labeled - identity unknown		UNSPECIFIED POLYMER, UNSPECIFIED COLOR

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Designated as safe for general or specific, limited use in food		CI 77499, SUCROSE ACETATE ISOBUTYRATE, ISOPROPYL ALCOHOL, ETHYL ACETATE, CITRIC ACID, CAMPHOR, BUTYL ACETATE
Used in food or as an additive with limited or no toxicity information available		SD ALCOHOL 1

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Suspected to be an environmental toxin		TRIMETHYL PENTANYL DIISOBUTYRATE
Not suspected to be an environmental toxin		POLYETHYLENE TEREPHTHALATE, NITROCELLULOSE, ISOPROPYL ALCOHOL
Wildlife and environmental toxicity		TOLUENE

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show skin irritation at high doses		SUCROSE ACETATE ISOBUTYRATE
One or more animal studies show skin irritation at moderate doses		TRIMETHYL PENTANYL DIISOBUTYRATE, CITRIC ACID
Classified as skin irritant	products for use on skin	TOLUENE, BUTYL ACETATE
Classified as irritant		ISOPROPYL ALCOHOL, ETHYL ACETATE

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Considered safe based on assumption of low absorption		TOLUENE
Insufficient data to determine safety		TOLUENE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		DIBUTYL ADIPATE
Considered safe based on assumption of low absorption		ACRYLATES COPOLYMER, STYRENE/ ACRYLATES COPOLYMER
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		TOLUENE, STEARALKONIUM HECTORITE, ETHYL ACETATE, BUTYL ACETATE, BENZOPHENONE-1
Not assessed for safety in cosmetics by industry panel		UNSPECIFIED POLYMER, SD ALCOHOL 1, POLYVINYL BUTYRAL, CI 77499, UNSPECIFIED COLOR, TRIPHENYL PHOSPHATE, TRIMETHYL PENTANYL DIISOBUTYRATE, SUCROSE ACETATE ISOBUTYRATE, STEARALKONIUM BENTONITE, POLYETHYLENE TEREPHTHALATE, PHTHALIC ANHYDRIDE/ TRIMELLITIC ANHYDRIDE/ GLYCOLS COPOLYMER, PANAX GINSENG (GINSENG) ROOT EXTRACT, NITROCELLULOSE, ISOPROPYL ALCOHOL, GUANINE, FERRIC AMMONIUM FERROCYANIDE, ETHYL TOSYLAMIDE, EQUISETUM ARVENSE (HORSETAIL) EXTRACT, CITRIC ACID, CAMPHOR, ADIPIC ACID/ NEOPENTYL GLYCOL/ TRIMELLITIC ANHYDRIDE COPOLYMER

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to low doses		FERRIC AMMONIUM FERROCYANIDE
Allowed workplace exposures restricted to moderate doses		CAMPHOR
Allowed workplace exposures restricted to low doses		TRIPHENYL PHOSPHATE, MICA
Allowed workplace exposures restricted to moderate doses		CI 77499
Allowed workplace exposures restricted to high doses		BUTYL ACETATE, ETHYL ACETATE, ISOPROPYL ALCOHOL, TOLUENE

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood		SILICA
One or more animal studies show biochemical changes at low doses where the human health implications are not yet well understood		CI 77499
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		CITRIC ACID, PANAX GINSENG (GINSENG) ROOT EXTRACT